Identification of determinants of referral and follow-up body mass index of adolescent patients with anorexia nervosa: evidence for the role of premorbid body weight

Abstract Background and Aims Overweight or obese patients with autosomal dominant polycystic kidney disease (ADPKD) are associated with the decline of glomerular filtration rate. However, little is known about the annual rate of change in total kidney volume (TKV) in patients with ADPKD according to the body mass index (BMI) corrected by TKV and total liver volume (TLV). Method We analyzed 364 patients with ADPKD from the KoreaN Cohort Study for Outcomes in Patients with Chronic Kidney Disease. We compared the changes in TKV in less than 1-year, 2-years and 4-year follow-up from patients by dividing baseline body mass index (BMI) by 18.5 to 22.9 (normal), 23 to 24.9 (overweight), and > 25 kg/m2 (obesity). Results During the 4-year follow-up period, TKV tended to increase statistically with increasing BMI (P = 0.032). Similarly, higher BMI group showed higher TKV than lower BMI group (P = 0.016). Conventional BMI is affected by TKV and TLV in advanced ADPKD patients. Therefore, we reclassified patients by corrected BMI using the adjusted body weight (body weight – TKV – TLV). Although the statistical significances between absolute value of TKV and corrected BMI groups were disappeared during the follow-up, TKV% change/year showed significantly higher in ADPKD patients with obesity among corrected BMI groups (normal; 20.2%, overweight; 17.6% and obesity; 30.6%, P for trend = 0.022) Conclusion Even after correcting the TKV and TVL, obese patients showed a high of TKV% change/year compared to non-obese patients with ADPKD.

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An untranslated insertion variant in the uncoupling protein 2 gene is not related to body mass index and changes in body weight during a 26-year follow-up in Danish Caucasian men

Diabetologia ◽

10.1007/s001250051312 ◽

1999 ◽

Vol 42 (12) ◽

pp. 1413-1416 ◽

Cited By ~ 28

Author(s):

L. T. Dalgaard ◽

T. I. A. Sørensen ◽

T. Andersen ◽

T. Hansen ◽

O. Pedersen

Keyword(s):

Body Mass Index ◽

Body Weight ◽

Body Mass ◽

Uncoupling Protein ◽

Uncoupling Protein 2 ◽

Caucasian Men

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Discharge Body Mass Index, Not Illness Chronicity, Predicts 6-Month Weight Outcome in Patients Hospitalized With Anorexia Nervosa

Frontiers in Psychiatry ◽

10.3389/fpsyt.2021.641861 ◽

2021 ◽

Vol 12 ◽

Author(s):

Graham W. Redgrave ◽

Colleen C. Schreyer ◽

Janelle W. Coughlin ◽

Laura K. Fischer ◽

Allisyn Pletch ◽

...

Keyword(s):

Body Mass Index ◽

Anorexia Nervosa ◽

Body Mass ◽

Adult Women ◽

Short Term ◽

Illness Duration ◽

Weight Restoration ◽

The Impact

Proposed treatments for severe and enduring anorexia nervosa (SE-AN) focus on quality of life, and psychological and social functioning. By de-emphasizing weight restoration as a priority, however, premature diagnosis of SE-AN may reduce potential for recovery. The present study assessed the effect of weight restoration, illness duration, and severity on treatment outcome 6 months after discharge from an intensive, meal-based behavioral treatment program. Participants included hospitalized adult women (N = 191) with AN or underweight other specified feeding and eating disorder (OSFED). Participants were characterized as short-term (ill <7 years; n = 74) or long-term ill (ill ≥ 7 years; n = 117). Compared with short-term ill, long-term ill patients were older, had lower lifetime body mass index (BMI), more prior admissions, and exhibited greater depression and neuroticism. Long-term vs. short-term ill patients gained weight at the same rate (~2 kg/wk) and were equally likely to be weight restored by discharge (>75% reached BMI ≥ 19 kg/m2 in both groups). At 6-month follow-up (n = 99), both groups had equivalent self-reported BMI, and depression, drive for thinness, body dissatisfaction, and bulimia scores. The only predictor of BMI ≥ 19 kg/m2 at follow-up was discharge BMI. The likelihood of a BMI ≥ 19 kg/m2 at follow-up was 5-fold higher for those with discharge BMI ≥ 19 kg/m2. Few studies of long-term ill inpatients with AN have examined the impact of full weight restoration on short-term outcomes. This study supports the therapeutically optimistic stance that, regardless of illness duration, hospitalized patients with AN benefit from gaining weight to a BMI ≥ 19 kg/m2.

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Body Weight and Body Mass Index Influence Bone Mineral Density in Late Adolescence in a Two‐Year Follow‐Up Study. The Tromsø Study: Fit Futures

JBMR Plus ◽

10.1002/jbm4.10195 ◽

2019 ◽

Vol 3 (9) ◽

Author(s):

Ole Andreas Nilsen ◽

Luai Awad Ahmed ◽

Anne Winther ◽

Tore Christoffersen ◽

Gyrd Thrane ◽

...

Keyword(s):

Bone Mineral Density ◽

Body Mass Index ◽

Body Weight ◽

Body Mass ◽

Bone Mineral ◽

Late Adolescence ◽

Mineral Density ◽

Follow Up Study

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The Gender-specific Role of Body Weight for Health, Earnings and Life Satisfaction in Piecewise and Simultaneous Equations Models

Jahrbücher für Nationalökonomie und Statistik ◽

10.1515/jbnst-2019-0002 ◽

2020 ◽

Vol 240 (5) ◽

pp. 653-676

Author(s):

Olaf Hübler

Keyword(s):

Body Mass Index ◽

Life Satisfaction ◽

Body Weight ◽

Body Mass ◽

Simultaneous Equations ◽

Overweight Women ◽

Overweight People ◽

Simultaneous Equations Models ◽

Gender Specific

AbstractBased on the German Socio-Economic Panel, the correlation between the body mass index, health, earnings and life satisfaction is analysed by gender. The previous literature has found no consistent results. This might have several reasons. The purpose of this paper is to analyse the gender-specific role of weight in single equation, piecewise and simultaneous equations models. We ask whether this distinction is important for the degree of association between health, earnings, satisfaction and body weight. In our context, piecewise modelling means a separate inspection of weight coefficients for under- and overweight people, allowing the detection of non-linear influences. As a benchmark, we begin our estimations under the assumption that the association between health, earnings, satisfaction, and weight is the same for under- and overweight people, and that there are no jointly dependent influences between our three outcome variables. The basic results are: health worsens, income declines and satisfaction is poorer with higher body mass index. If the association with weight is separately determined for over- and underweight people, the estimates show striking differences between overweight men and women. Underweight women earn more and overweight less than others. For normal-weight men the income is on average higher than for over- and underweight men but this difference is insignificant. When matching and instrumental variables procedures are applied, the health outcome for overweight people matches that of independent and unmatched estimates. Stronger positive effects on health are found for underweight women. No clear-cut advantages in income of overweight women can be found. Underweight women and especially underweight men tend to be less happy. For overweight men this influence is ambiguous but more speaks in favour of a lesser level of satisfaction. Overweight women seem to be happier.

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Serum Omentin Levels in Adolescent Girls With Anorexia Nervosa and Obesity

Physiological Research ◽

10.33549/physiolres.932841 ◽

2015 ◽

pp. 701-709 ◽

Cited By ~ 12

Author(s):

J. OŚWIĘCIMSKA ◽

A. SUWAŁA ◽

E. ŚWIĘTOCHOWSKA ◽

Z. OSTROWSKA ◽

P. GORCZYCA ◽

...

Keyword(s):

Insulin Resistance ◽

Body Mass Index ◽

Body Weight ◽

Anorexia Nervosa ◽

Body Mass ◽

Standard Deviation Score ◽

Cross Sectional Study ◽

Serum Concentrations ◽

Cross Sectional ◽

Wide Range

It is believed that omentin is secreted by stromal cells of adipose tissue and modulates insulin sensitivity. Data from a few studies have shown lower serum omentin in obese children and higher in anorexia nervosa. However, to date, there is lack of research on serum omentin concentrations in adolescent patients in a wide range of body mass index (BMI) and insulin resistance. In this cross-sectional study omentin-1 serum concentrations were evaluated using commercially available ELISA kit in 47 Polish girls with restrictive anorexia nervosa (AN), 50 with simple obesity (OB) and 39 healthy controls (C). The mean serum omentin-1 concentration in girls with AN was statistically significantly higher than that of C and OB girls. Statistically significant (P<0.0001) negative correlations between the serum concentrations of omentin-1 and body weight (r=−0.73), BMI (r=−0.75), standard deviation score for body mass index (BMI-SDS) (r=−0.75), insulin (r=−0.81) and HOMA-IR index (r=−0.82) were seen in the entire examined population. We conclude, that omentin-1 is the nutritional marker reflecting body weight and insulin resistance. Our findings support the hypothesized role of omentin in maintenance of body weight and regulation of appetite and suggest the adaptation of its secretion to body weight and glucose metabolism.

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Effects of “Bacuri” Seed Butter (Platonia insignis Mart.) on Metabolic Parameters in Hamsters with Diet-Induced Hypercholesterolemia

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2021/5584965 ◽

2021 ◽

Vol 2021 ◽

pp. 1-8

Author(s):

Geovanni de Morais Lima ◽

Ana Karolinne da Silva Brito ◽

Luciana Melo de Farias ◽

Lays Arnaud Rosal Lopes Rodrigues ◽

Cristian Francisco de Carvalho Pereira ◽

...

Keyword(s):

Body Mass Index ◽

Body Weight ◽

Liver Function ◽

Lipid Profile ◽

Total Cholesterol ◽

Body Mass ◽

Risk Index ◽

Atherogenic Index ◽

Weight Growth

This study aimed to evaluate the effects of the treatment with bacuri seed butter (BB) on body weight, growth, body mass index, lipid profile, atherosclerotic indices, and liver function in dyslipidemic hamsters. Freshly weaned, male hamsters were divided into four groups: (1) normal group (NG)—maintained with standard chow (AIN-93G); (2) dyslipidemia group (DG)—maintained with hyperlipidemic chow (AIN-93G modified) throughout the follow-up period; (3) bacuri seed butter 25 mg/kg/day (BB-25); and (4) bacuri seed butter 50 mg/kg/day (BB-50). BB groups (25 and 50 mg/kg/day) were also maintained with hyperlipidemic chow throughout the follow-up period, and the treatment started after 21 days receiving a hyperlipidemic diet to induce hypercholesterolemia and maintained for 28 days. No significant differences in triglycerides and total cholesterol were observed for BB-25 and BB-50 groups when compared with NG and DG groups. On the contrary, BB-25 and BB-50 induced both increase of HDL-c (51.40 ± 1.69 and 51.00 ± 2.34, respectively) and decrease of LDL-c (103.80 ± 6.87 and 100.50 ± 3.95, respectively) when compared with DG (41.00 ± 2.94 and 132.70 ± 9.41, respectively). In addition, BB promoted a reduction in the risk of atherosclerotic disease by decreasing p < 0.05 the atherogenic index, coronary artery risk index, and LDL/CT ratio p < 0.05 and increasing HDL/CT ratio. On the contrary, no changes were observed in total cholesterol and triglyceride levels or in body weight, growth, body mass index, or liver function parameters. Thus, bacuri seed butter at doses of 25 and 50 mg/kg/day has positive repercussions on the lipid profile, more precisely on plasma HDL-c and LDL-c, and additionally promotes reduction in the risk of atherosclerosis in hamsters.

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