scholarly journals An untranslated insertion variant in the uncoupling protein 2 gene is not related to body mass index and changes in body weight during a 26-year follow-up in Danish Caucasian men

Diabetologia ◽  
1999 ◽  
Vol 42 (12) ◽  
pp. 1413-1416 ◽  
Author(s):  
L. T. Dalgaard ◽  
T. I. A. Sørensen ◽  
T. Andersen ◽  
T. Hansen ◽  
O. Pedersen
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Body Mass ◽  
Uncoupling Protein ◽  
Uncoupling Protein 2 ◽  
Caucasian Men

P0708ASSOCIATION OF OBESITY WITH KIDNEY CYST GROWTH IN PATIENTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE; RESULTS FROM KNOW-CKD COHORT DATA

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Chang Seong Kim ◽  
Hong Sang Choi ◽  
Eun hui Bae ◽  
Seong Kwon Ma ◽  
Soo Wan Kim
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Body Mass ◽  
Autosomal Dominant ◽  
Obese Patients ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney

Abstract Background and Aims Overweight or obese patients with autosomal dominant polycystic kidney disease (ADPKD) are associated with the decline of glomerular filtration rate. However, little is known about the annual rate of change in total kidney volume (TKV) in patients with ADPKD according to the body mass index (BMI) corrected by TKV and total liver volume (TLV). Method We analyzed 364 patients with ADPKD from the KoreaN Cohort Study for Outcomes in Patients with Chronic Kidney Disease. We compared the changes in TKV in less than 1-year, 2-years and 4-year follow-up from patients by dividing baseline body mass index (BMI) by 18.5 to 22.9 (normal), 23 to 24.9 (overweight), and > 25 kg/m2 (obesity). Results During the 4-year follow-up period, TKV tended to increase statistically with increasing BMI (P = 0.032). Similarly, higher BMI group showed higher TKV than lower BMI group (P = 0.016). Conventional BMI is affected by TKV and TLV in advanced ADPKD patients. Therefore, we reclassified patients by corrected BMI using the adjusted body weight (body weight – TKV – TLV). Although the statistical significances between absolute value of TKV and corrected BMI groups were disappeared during the follow-up, TKV% change/year showed significantly higher in ADPKD patients with obesity among corrected BMI groups (normal; 20.2%, overweight; 17.6% and obesity; 30.6%, P for trend = 0.022) Conclusion Even after correcting the TKV and TVL, obese patients showed a high of TKV% change/year compared to non-obese patients with ADPKD.

scholarly journals Body Weight and Body Mass Index Influence Bone Mineral Density in Late Adolescence in a Two‐Year Follow‐Up Study. The Tromsø Study: Fit Futures

JBMR Plus ◽  
2019 ◽  
Vol 3 (9) ◽  
Author(s):  
Ole Andreas Nilsen ◽  
Luai Awad Ahmed ◽  
Anne Winther ◽  
Tore Christoffersen ◽  
Gyrd Thrane ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Body Mass Index ◽  
Body Weight ◽  
Body Mass ◽  
Bone Mineral ◽  
Late Adolescence ◽  
Mineral Density ◽  
Follow Up Study

scholarly journals Effects of “Bacuri” Seed Butter (Platonia insignis Mart.) on Metabolic Parameters in Hamsters with Diet-Induced Hypercholesterolemia

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Geovanni de Morais Lima ◽  
Ana Karolinne da Silva Brito ◽  
Luciana Melo de Farias ◽  
Lays Arnaud Rosal Lopes Rodrigues ◽  
Cristian Francisco de Carvalho Pereira ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Liver Function ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Body Mass ◽  
Risk Index ◽  
Atherogenic Index ◽  
Weight Growth

This study aimed to evaluate the effects of the treatment with bacuri seed butter (BB) on body weight, growth, body mass index, lipid profile, atherosclerotic indices, and liver function in dyslipidemic hamsters. Freshly weaned, male hamsters were divided into four groups: (1) normal group (NG)—maintained with standard chow (AIN-93G); (2) dyslipidemia group (DG)—maintained with hyperlipidemic chow (AIN-93G modified) throughout the follow-up period; (3) bacuri seed butter 25 mg/kg/day (BB-25); and (4) bacuri seed butter 50 mg/kg/day (BB-50). BB groups (25 and 50 mg/kg/day) were also maintained with hyperlipidemic chow throughout the follow-up period, and the treatment started after 21 days receiving a hyperlipidemic diet to induce hypercholesterolemia and maintained for 28 days. No significant differences in triglycerides and total cholesterol were observed for BB-25 and BB-50 groups when compared with NG and DG groups. On the contrary, BB-25 and BB-50 induced both increase of HDL-c (51.40 ± 1.69 and 51.00 ± 2.34, respectively) and decrease of LDL-c (103.80 ± 6.87 and 100.50 ± 3.95, respectively) when compared with DG (41.00 ± 2.94 and 132.70 ± 9.41, respectively). In addition, BB promoted a reduction in the risk of atherosclerotic disease by decreasing p < 0.05 the atherogenic index, coronary artery risk index, and LDL/CT ratio p < 0.05 and increasing HDL/CT ratio. On the contrary, no changes were observed in total cholesterol and triglyceride levels or in body weight, growth, body mass index, or liver function parameters. Thus, bacuri seed butter at doses of 25 and 50 mg/kg/day has positive repercussions on the lipid profile, more precisely on plasma HDL-c and LDL-c, and additionally promotes reduction in the risk of atherosclerosis in hamsters.

scholarly journals An uncoupling protein 2 gene variant is associated with a raised body mass index but not Type II diabetes

Diabetologia ◽  
1999 ◽  
Vol 42 (6) ◽  
pp. 688-692 ◽  
Author(s):  
P. G. Cassell ◽  
M. Neverova ◽  
S. Janmohamed ◽  
N. Uwakwe ◽  
A. Qureshi ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Type Ii Diabetes ◽  
Uncoupling Protein ◽  
Uncoupling Protein 2 ◽  
Type Ii ◽  
Gene Variant

scholarly journals Body Mass Index in Young Women and Risk of Cardiomyopathy

Circulation ◽  
2020 ◽  
Vol 141 (7) ◽  
pp. 520-529 ◽  
Author(s):  
Josefina Robertson ◽  
Martin Lindgren ◽  
Maria Schaufelberger ◽  
Martin Adiels ◽  
Lena Björck ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Dilated Cardiomyopathy ◽  
Body Mass ◽  
Young Women ◽  
Childbearing Age ◽  
Medical Birth Register ◽  
Increased Risk ◽  
Increase In Risk

Background: Incidence rates of cardiomyopathies, which are a common cause of heart failure in young people, have increased during the last decades. An association between body weight in adolescence and future cardiomyopathy among men was recently identified. Whether or not this holds true also for women is unknown. The aim was therefore to determine whether for young women being overweight or obese is associated with a higher risk of developing cardiomyopathy. Methods: This was a registry-based national prospective cohort study with data collected from the Swedish Medical Birth Register, 1982 to 2014, with up to 33 years of follow-up. Included women were of childbearing age (18–45 years) during the initial antenatal visit in their first or second pregnancy (n=1 393 346). We obtained baseline data on body mass index (BMI), smoking, education, and previous disorders. After exclusions, mainly because of previous disorders, the final sample was composed of 1 388 571 women. Cardiomyopathy cases were identified by linking the Medical Birth Register to the National Patient and Cause of Death registers. Results: In total, we identified 1699 cases of cardiomyopathy (mean age at diagnosis, 46.2 [SD 9.1] years) during the follow-up with an incidence rate of 5.9 per 100 000 observation years. Of these, 481 were diagnosed with dilated cardiomyopathy, 246 had hypertrophic cardiomyopathy, 61 had alcohol/drug-induced cardiomyopathy, and 509 had other forms. The lowest risk for being diagnosed with a cardiomyopathy was detected at a BMI of 21 kg/m 2 , with a gradual increase in risk with higher BMI, particularly for dilated cardiomyopathy, where a hazard ratio of 4.71 (95% CI, 2.81–7.89) was found for severely obese subjects (BMI ≥35 kg/m 2 ), as compared with BMI 20 to <22.5. Conclusions: Elevated BMI among young women was associated with an increased risk of being diagnosed with a subsequent cardiomyopathy, especially dilated cardiomyopathy, starting already at mildly elevated body weight, whereas severe obesity entailed an almost 5-fold increase in risk. With the increasing numbers of persons who are overweight or obese, higher rates of cardiomyopathy can be expected in the future, along with an altered disease burden related to adiposity.

scholarly journals Consensus on the principles of physical development monitoring in children, possible or not?

2020 ◽  
Vol 16 (3) ◽  
pp. 268-274
Author(s):  
Anna Świąder-Leśniak ◽  
◽  
Anna Majcher ◽  
Beata Pyrżak ◽  
Piotr Dziechciarz ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Body Mass ◽  
Negative Impact ◽  
Well Being ◽  
Anthropometric Measurements ◽  
World Health ◽  
Health Organization

Regular, long-term anthropometric follow-up is one of the fundamental methods of assessing the child’s health and well-being. However, there is still a lot of inconsistency in anthropometric practices and standards that may have a negative impact on clinical practice (e.g. delay in diagnosing children with growth or feeding disorders, genetic and metabolic syndromes). The paper discusses the principles of basic measurements: length/height, body weight, circumferences: head, chest and arm. Attention was also paid to the use of professional anthropometric equipment. Appropriately performed measurements allow the calculation of weight-height indices, which define nutrition disturbances (overweight, obesity and malnutrition), and also constitute the basis for conducting specialised diagnostics. In 2011, a group of experts recommended standards of body length/height, body weight, head circumference and body mass index developed by the World Health Organization for children up to 5 years of age. In 2013, nationwide reference values for weight, height and body mass index for children aged from 3 to 6 years were published and accepted as valid (OLA project). They complemented previously developed percentile charts for children aged 7–18 years (OLAF project). The paper proposes to adopt uniform standards of anthropometric measurements and to initiate a discussion in the paediatric community on the acceptance of common growth charts for the basic anthropometric measurements.

Abstract P208: Changes in metabolic profiles among evacuees after the Great East Japan Earthquake: the Fukushima Health Management Survey

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Tetsuya Ohira ◽  
Mitsuaki Hosoya ◽  
Seiji Yasumura ◽  
Hiroaki Sato ◽  
Hitoshi Suzuki ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Body Mass Index ◽  
Body Weight ◽  
Body Mass ◽  
Great East Japan Earthquake ◽  
Metabolic Profiles ◽  
Before And After ◽  
Prevalence Of Obesity ◽  
Obesity Hypertension

Background: The Great East Japan Earthquake occurred on 11 March 2011 in Japan. To this day, over 140,000 people have been forced to evacuate their homes due to a nuclear accident, which occurred at the Fukushima Daiichi Nuclear Power Plant. Hypothesis: We assessed the hypothesis that prevalence of obesity, hypertension, dyslipidemia, and diabetes mellitus was increased among evacuees after the disaster, compared with that before the disaster. Methods: A prospective study of Japanese subjects aged 40-90 years was undertaken using data collected from 32,949 participants (14,963 men and 17,986 women) in general health checkups conducted in 12 communities, including the evacuation zone specified by the government, between 2008 and 2010. Height, body weight, blood pressure, and blood test such as glucose, hemoglobin A1c (HbA1c), and lipid panel were examined. Follow-up examination was conducted between 2011 and 2012 (at least of 6-month after the disaster). The participants were divided into two groups: evacuees and non-evacuees. Changes in metabolic profiles among the evacuees and non-evacuees were compared between before and after the disaster. Results: 22,117 participants (10,170 men and 11,947 women, follow-up rate: 67%) received follow-up examination after the disaster, and an average follow up was 1.5-years. Mean levels of body weight were significantly increased in the both evacuee and non-evacuee groups after the disaster, and changes in body weight and body mass index were greater in the evacuee group than those in the non-evacuee group; +1.3kg versus +0.3kg, p<0.001, and +0.60kg/m 2 versus +0.13kg/m 2 , p<0.001. In the evacuee group, prevalence of obesity, hypertension, dyslipidemia, and diabetes mellitus was increased after the disaster. Respective prevalence before and after the disaster were 31.8% and 39.4% for obesity (body mass index>=25.0kg/m 2 ), 54.2% and 60.2% for hypertension, 41.2% and 53.9% for dyslipidemia, and 10.2% and 11.9% for diabetes mellitus, while, in the non-evacuee group, those were 28.3% and 30.3%, 54.7% and 60.0%, 42.6% and 49.4%, and 8.5% and 9.9%. Conclusions: Prevalence of obesity, hypertension, dyslipidemia, and diabetes mellitus may be increased among residents, especially evacuees, in the evacuation zone of Fukushima prefecture after the Great East Japan Earthquake.

scholarly journals Impact of the Duration and Degree of Hypertension and Body Weight on New-Onset Atrial Fibrillation

Hypertension ◽  
2019 ◽  
Vol 74 (5) ◽  
Author(s):  
Yun Gi Kim ◽  
Kyung-Do Han ◽  
Jong-Il Choi ◽  
Ki Yung Boo ◽  
Do Young Kim ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Body Mass Index ◽  
Body Weight ◽  
Waist Circumference ◽  
Body Mass ◽  
Weight Status ◽  
Obese People ◽  
Body Weight Status ◽  
New Onset

Hypertension and obesity are known risk factors for atrial fibrillation (AF). However, it is unclear whether uncontrolled, long-standing hypertension has a particularly profound effect on AF. Because they have a similar underlying pathophysiology, hypertension and obesity could act synergistically in the context of AF. We evaluated how various stages of hypertension and body weight status affect new-onset AF. We analyzed a total of 9 797 418 participants who underwent a national health checkup. Hypertension was classified into 5 stages: nonhypertension, prehypertension, hypertension without medication, hypertension with medication <5 years, and hypertension with medication ≥5 years. The participants were also stratified based on body mass index and waist circumference. During the 80 130 161 person×years follow-up, a total of 196 136 new-onset AF cases occurred. The incidence of new-onset AF gradually increased among the 5 stages of hypertension: the adjusted hazard ratio for each group was 1 (reference), 1.145, 1.390, 1.853, and 2.344 for each stage of hypertension. A graded escalation in the risk of new-onset AF was also observed in response to increased systolic and diastolic blood pressure. The incidence of new-onset AF correlated with body mass index and waist circumference, with obese people having a higher risk than others. Hypertension and obesity acted synergistically: obese people with hypertension on medication ≥5 years had the highest risk of AF. In conclusion, the degree and duration of hypertension, as well as the presence of hypertension, were important factors for new-onset AF. Body weight status was significantly associated with new-onset AF and acted synergistically with hypertension.

Body weight in acute anorexia nervosa and at follow-up assessed with percentiles for the body mass index: Implications of a low body weight at referral

1996 ◽  
Vol 19 (4) ◽  
pp. 347-357 ◽  
Author(s):  
Johannes Hebebrand ◽  
G�nther W. Himmelmann ◽  
Christoph Wewetzer ◽  
Cornelius Gutenbrunner ◽  
Helmut Heseker ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Anorexia Nervosa ◽  
Body Mass ◽  
The Body
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