Chemical Composition and Tyrosinase Inhibitory Activity of the Essential Oil of Rhodamnia cinerea

Abstract The objective of the present paper was the assessment of the chemical composition of the essential oils from four Asteraceae species with a considerable food, medicinal, and agricultural value, collected in Egypt, together with their in vitro inhibitory activity against molds and yeasts. The essential oil of Launaea cornuta flowers was also evaluated for the first time, but because of its very low yield (<0.01%), no antifungal test was performed.

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Chemical composition and α-amylase inhibitory activity of the essential oil from Sabina chinensis cv. Kaizuca leaves

Natural Product Research ◽

10.1080/14786419.2017.1332612 ◽

2017 ◽

Vol 32 (6) ◽

pp. 711-713 ◽

Cited By ~ 6

Author(s):

Dongyu Gu ◽

Chen Fang ◽

Jiao Yang ◽

Minjing Li ◽

Hengming Liu ◽

...

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Inhibitory Activity

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Chemical Composition andα-Glucosidase Inhibitory Activity of VietnameseCitrusPeels Essential Oils

Journal of Chemistry ◽

10.1155/2016/6787952 ◽

2016 ◽

Vol 2016 ◽

pp. 1-5 ◽

Cited By ~ 4

Author(s):

Nguyen Hai Dang ◽

Pham Huong Nhung ◽

Bui Thi Mai Anh ◽

Dinh Thi Thu Thuy ◽

Chau Van Minh ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Chemical Composition ◽

Essential Oil ◽

Essential Oils ◽

Inhibitory Activity ◽

Inhibitory Effect ◽

Potential Use

Background. Inhibition ofα-glucosidase is an important factor to control postprandial hyperglycemia in type 2 diabetes mellitus.Citrusessential oils (CEO) are among the most widely used essential oils, and some of them exhibited promising antidiabetic effect. However, theα-glucosidase inhibition of CEO has not been investigated so far. The present work aims to evaluate theα-glucosidase inhibition of essential oils from six VietnameseCitruspeels.Methods. The chemical composition of essential oils obtained by hydrodistillation from sixCitruspeels was analyzed by GC-MS. All essential oils were tested for their inhibitory activity onα-glucosidase usingp-nitrophenyl-α-D-glucopyranoside as substrate.Results. In Buddha’s hand and lime peels, the major components were limonene (59.0–61.31%) andγ-terpinene (13.98–23.84%) while limonene (90.95–95.74%) was most abundant in pomelo, orange, tangerine, and calamondin peels. Among the essential oils, the Buddha’s hand oil showed the most significantα-glucosidase inhibitory effect with the IC50value of 412.2 μg/mL. The combination of the Buddha’s hand essential oil and the antidiabetic drug acarbose increased the inhibitory effect.Conclusions. The results suggested the potential use of Buddha’s hand essential oil as an alternative in treatment of type 2 diabetes mellitus.

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Camellia japonica Essential Oil Inhibits α-MSH-Induced Melanin Production and Tyrosinase Activity in B16F10 Melanoma Cells

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2021/6328767 ◽

2021 ◽

Vol 2021 ◽

pp. 1-8

Author(s):

Si Young Ha ◽

Ji Young Jung ◽

Jae-Kyung Yang

Keyword(s):

Essential Oil ◽

Inhibitory Activity ◽

Treated Group ◽

Inhibitory Effect ◽

Positive Control ◽

Tyrosinase Activity ◽

Gas Chromatography Mass Spectrometry ◽

Camellia Japonica ◽

Tyrosinase Inhibitory Activity ◽

Natural Substances

Essential oils are aromatic oils extracted from the leaves, stems, peels, petals, and roots of aromatic plants grown in nature or grown in organic methods and have various medical effects as natural substances. The essential oil extracted from Camellia japonica seeds exhibits various functional properties; however, its tyrosinase inhibitory activity has not been investigated extensively. This study is performed to investigate the chemical composition and tyrosinase inhibitory activity of Camellia japonica seed essential oil (CJS-EO). Hexamethylcyclotrisiloxane (42.36%) and octamethylcyclotetrasiloxane (23.28%) are the two primary components of CJS-EO, as identified via gas chromatography-mass spectrometry. The inhibitory activities of CJS-EO and positive control arbutin are further evaluated against mushroom tyrosinase. The results show that CJS-EO and arbutin inhibit tyrosinase activity. Moreover, CJS-EO significantly inhibits melanogenesis in the α-melanocyte-stimulating hormone-treated group, and a significant amount of melanin is suppressed. To ascertain the cause of the CJS-EO tyrosinase inhibitory effect and melanin reduction effect, genetic and protein analyses are performed. Based on our results, we tentatively conclude that CJS-EO can inhibit melanocytes from harmful factors such as tyrosinase-related protein. These results demonstrate that CJS-EO possesses potent antityrosinase activity and may be a good skin-whitening agent.

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Chemical composition and in vitro anticholinesterase inhibitory activity of Citrus medica L. cv. Diamante essential oil

Planta Medica ◽

10.1055/s-0029-1234808 ◽

2009 ◽

Vol 75 (09) ◽

Author(s):

F Menichini ◽

R Tundis ◽

MR Loizzo ◽

M Bonesi ◽

F Conforti ◽

...

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Inhibitory Activity ◽

Citrus Medica

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Chemical Composition and Anticholinesterase Activity of the Essential Oil of Leaves and Flowers from the Ecuadorian Plant Lepechinia paniculata (Kunth) Epling

Molecules ◽

10.3390/molecules26113198 ◽

2021 ◽

Vol 26 (11) ◽

pp. 3198

Author(s):

María Fernanda Panamito ◽

Nicole Bec ◽

Valeria Valdivieso ◽

Melissa Salinas ◽

James Calva ◽

...

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Inhibitory Activity ◽

Steam Distillation ◽

Ionization Detector ◽

Flame Ionization ◽

Enantiomeric Analysis ◽

Aerial Parts ◽

Cholinesterase Inhibitory Activity ◽

Ic50 Values

This work aimed to study the chemical composition, cholinesterase inhibitory activity, and enantiomeric analysis of the essential oil from the aerial parts (leaves and flowers) of the plant Lepechinia paniculata (Kunth) Epling from Ecuador. The essential oil (EO) was obtained through steam distillation. The chemical composition of the oil was evaluated by gas chromatography, coupled to mass spectrometry (GC–MS) and a flame ionization detector (GC-FID). The analyses led to the identification of 69 compounds in total, of which 40 were found in the leaves and 29 were found in the flowers of the plant. The major components found in the oil were 1,8-Cineole, β-Pinene, δ-3-Carene, α-Pinene, (E)-Caryophyllene, Guaiol, and β-Phellandrene. Flower essential oil showed interesting selective inhibitory activity against both enzymes AChE (28.2 ± 1.8 2 µg/mL) and BuChE (28.8 ± 1.5 µg/mL). By contrast, the EO of the leaves showed moderate mean inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with IC50 values of 38.2 ± 2.9 µg/mL and 47.4 ± 2.3 µg/mL, respectively.

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Chemical composition and acetylcholinesterase inhibitory activity of essential oil from rhizomes of Distichochlamys benenica

HUE UNIVERSITY JOURNAL OF SCIENCE NATURAL SCIENCE ◽

10.26459/hueunijns.v129i1d.5804 ◽

2021 ◽

Vol 129 (1D) ◽

pp. 43-49

Author(s):

Hanh Thi Nhu Hoang ◽

Thanh Thu Thi Dinh ◽

Ty Viet Pham ◽

Hien Bich Thi Le ◽

Duc Viet Ho

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Inhibitory Activity ◽

Acetylcholinesterase Activity ◽

Acetylcholinesterase Inhibitory Activity ◽

Ic50 Value

Twenty-seven constituents were identified by using GC/MS, representing 99.57% of the rhizome oil of Distichochlamys benenica. The major constituents of the essential oil are 1,8-cineole (54.39%), β-pinene (7.50%), (E)-citral (7.26%), and (Z)-citral (6.79%). The rhizome essential oil has anti-acetylcholinesterase activity with an IC50 value of 136.63 ± 2.70 mg/mL.

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Chemical composition and anticholinesterase inhibitory activity of Pavetta graciliflora Wall. ex Ridl. essential oil

Zeitschrift für Naturforschung C ◽

10.1515/znc-2020-0075 ◽

2020 ◽

Vol 75 (11-12) ◽

pp. 467-471

Author(s):

Wan Mohd Nuzul Hakimi Wan Salleh ◽

Shamsul Khamis

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Chemical Composition ◽

Essential Oil ◽

Inhibitory Activity ◽

Anticholinesterase Activity ◽

Gas Chromatography Mass Spectrometry ◽

Caryophyllene Oxide ◽

Total Oil ◽

First Time

AbstractChemical composition and anticholinesterase activity of the essential oil of Pavetta graciliflora Wall. ex Ridl. (Rubiaceae) was examined for the first time. The essential oil was obtained by hydrodistillation and was fully characterized by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of 20 components were identified in the essential oil, which made up 92.85% of the total oil. The essential oil is composed mainly of β-caryophyllene (42.52%), caryophyllene oxide (25.33%), β-pinene (8.67%), and α-pinene (6.52%). The essential oil showed weak inhibitory activity against acetylcholinesterase (AChE) (I%: 62.5%) and butyrylcholinesterase (BChE) (I%: 65.4%) assays. Our findings were shown to be very useful for the characterization, pharmaceutical, and therapeutic applications of the essential oil from P. graciliflora.

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Chemical Composition and Inhibitory Activity of Essential Oil from Decaying Leaves of Eucalyptus citriodora

Zeitschrift für Naturforschung C ◽

10.1515/znc-2006-1-210 ◽

2006 ◽

Vol 61 (1-2) ◽

pp. 52-56 ◽

Cited By ~ 24

Author(s):

Daizy R. Batish ◽

Harminder Pal Singh ◽

Nidhi Setia ◽

Shalinder Kaur ◽

Ravinder K. Kohli

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Weed Management ◽

Inhibitory Activity ◽

Root Length ◽

Root Elongation ◽

Volatile Oil ◽

Eucalyptus Citriodora ◽

Cassia Occidentalis ◽

Leaf Oil

Abstract A study was undertaken to explore the content and composition of volatile oil from decaying leaves of lemon-scented eucalypt (Eucalyptus citriodora Hook.) not analyzed earlier. GC and GC-MS analysis of the oil (yield 0.6%) revealed the monoterpenoid nature with citronellal (52.2%), citronellol (12.3%) and isoisopulegol (11.9%) as the major constituents. Overall, 17 components were identified that accounted for over 94% of the decaying leaf oil. Surprisingly, the decaying leaf oil contained nearly 1.8% of trans-rose oxide, which is generally absent in eucalypt essential oil. Decaying leaf oil and its major 2 components (citronellal and citronellol) inhibited the germination and root elongation of two weeds D Cassia occidentalis (broad-leaved) and Echinochloa crus-galli (grassy weed). Based on the dose-response studies, I50 values were determined for decaying leaf oil and the effect was more on germination only of broad-leaved weed (C. occidentalis), whereas that of citronellal and citronellol were on germination as well as root length of E. crus-galli (grassy weed). Based on I50 values it was observed that citronellal was more phytotoxic and germination inhibiting in nature, whereas citronellol was a more potent root inhibitor, thereby indicating a possible different mode of action. The study concludes that decaying leaf oil hold a good commercial value for exploitation as weed management agent

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