scholarly journals Age-specific trends in cardiovascular mortality rates in the Netherlands between 1980 and 2009

2011 ◽  
Vol 26 (5) ◽  
pp. 369-373 ◽  
Author(s):  
Anna Peeters ◽  
Wilma J. Nusselder ◽  
Christopher Stevenson ◽  
Edward J. Boyko ◽  
Lynelle Moon ◽  
...  
Keyword(s):  
The Netherlands ◽  
Cardiovascular Mortality ◽  
Mortality Rates

scholarly journals Attributable mortality of vancomycin resistance in ampicillin-resistant Enterococcus faecium bacteremia in Denmark and the Netherlands: A matched cohort study

2021 ◽  
pp. 1-9
Author(s):  
Wouter C. Rottier ◽  
Mette Pinholt ◽  
Akke K. van der Bij ◽  
Magnus Arpi ◽  
Sybrandus N. Blank ◽  
...  
Keyword(s):  
Cohort Study ◽  
The Netherlands ◽  
Antibiotic Therapy ◽  
Enterococcus Faecium ◽  
Mortality Rates ◽  
Vancomycin Resistance ◽  
Attributable Mortality ◽  
Matched Cohort ◽  
Matched Cohort Study ◽  
The Impact

Abstract Objective: To study whether replacement of nosocomial ampicillin-resistant Enterococcus faecium (ARE) clones by vancomycin-resistant E. faecium (VRE), belonging to the same genetic lineages, increases mortality in patients with E. faecium bacteremia, and to evaluate whether any such increase is mediated by a delay in appropriate antibiotic therapy. Design: Retrospective, matched-cohort study. Setting: The study included 20 Dutch and Danish hospitals from 2009 to 2014. Patients: Within the study period, 63 patients with VRE bacteremia (36 Dutch and 27 Danish) were identified and subsequently matched to 234 patients with ARE bacteremia (130 Dutch and 104 Danish) for hospital, ward, length of hospital stay prior to bacteremia, and age. For all patients, 30-day mortality after bacteremia onset was assessed. Methods: The risk ratio (RR) reflecting the impact of vancomycin resistance on 30-day mortality was estimated using Cox regression with further analytic control for confounding factors. Results: The 30-day mortality rates were 27% and 38% for ARE in the Netherlands and Denmark, respectively, and the 30-day mortality rates were 33% and 48% for VRE in these respective countries. The adjusted RR for 30-day mortality for VRE was 1.54 (95% confidence interval, 1.06–2.25). Although appropriate antibiotic therapy was initiated later for VRE than for ARE bacteremia, further analysis did not reveal mediation of the increased mortality risk. Conclusions: Compared to ARE bacteremia, VRE bacteremia was associated with higher 30-day mortality. One explanation for this association would be increased virulence of VRE, although both phenotypes belong to the same well-characterized core genomic lineage. Alternatively, it may be the result of unmeasured confounding.

scholarly journals The Hardness of Drinking Water Negatively while Socio-Economic Deprivation Positively Correlate with the Age-Adjusted Mortality Rates due to Cardiovascular Diseases in Hungarian Wine Regions

2019 ◽  
Vol 16 (18) ◽  
pp. 3437 ◽  
Author(s):  
Nagy ◽  
Sipka ◽  
SipkaJr ◽  
Kocsis ◽  
Horváth
Keyword(s):  
Drinking Water ◽  
Cardiovascular Diseases ◽  
Cardiovascular Mortality ◽  
Mortality Rates ◽  
Total Hardness ◽  
Red Wines ◽  
Economic Deprivation ◽  
White Wines ◽  
Economic State ◽  
Wine Region

We compared the age-adjusted death rates (AADR) for cardiovascular diseases (CVD) among 206,159 inhabitants analyzed between 2000 and 2010 in four wine territories of Hungary: Tokaj (white wines), Eger (mostly red wines), Balaton (mostly white wines), Szekszárd-Villány (mostly red wines) and Hódmezővásárhely (HMV) (not a wine region). The mortality rates were also assessed from the aspects of total hardness of drinking water and index of socio-economic deprivation (ID). We found the highest cardiovascular mortality in the Tokaj region and HMV. On the other hand, lower numbers of CVD were observed in Szekszárd-Villány, Balaton and Eger. These findings on cardiovascular mortality correlated negatively and significantly with the values of total hardness of drinking waters, which were low in Tokaj and HMV. They were higher in Szekszárd-Villány, Balaton and Eger. Additionally, and surprisingly, the mortality of CVD correlated positively and significantly with the ID values despite of the small numeric differences. The hardness of drinking water and the level of socio-economic state seem to have a greater impact on the mortality rate of CVD than the consumption of “red” or “white” dominant types of wines at a region. This study shows data on a population larger than 200,000 persons.

scholarly journals Dairy consumption and 10-y total and cardiovascular mortality: a prospective cohort study in the Netherlands

2011 ◽  
Vol 93 (3) ◽  
pp. 615-627 ◽  
Author(s):  
R. A. Goldbohm ◽  
A. M. Chorus ◽  
F. Galindo Garre ◽  
L. J. Schouten ◽  
P. A. van den Brandt
Keyword(s):  
Cohort Study ◽  
The Netherlands ◽  
Prospective Cohort Study ◽  
Cardiovascular Mortality ◽  
Prospective Cohort ◽  
Dairy Consumption

scholarly journals Beverage-Specific Alcohol Sale and Cardiovascular Mortality in Russia

2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Y. E. Razvodovsky
Keyword(s):  
Cardiovascular Mortality ◽  
Alcoholic Beverage ◽  
Mortality Rates ◽  
Alcoholic Beverages ◽  
Mortality Data ◽  
Male And Female ◽  
Distilled Spirits ◽  
Russian State ◽  
Female Rate ◽  
Cvd Mortality

Objective. Recent research evidence suggests that the consumption of different types of alcoholic beverage may have a differential effect on cardiovascular diseases (CVD) mortality rates. The aim of this study was to examine the relation between the consumption of different beverage types and CVD mortality rates in Russia across the later-Soviet and post-Soviet periods.Method. Age-standardized male and female CVD mortality data for the period 1970–2005 and data on beverage-specific alcohol sales were obtained Russian State Statistical Committee (Rosstat). Time-series analytical modeling techniques (ARIMA) were used to examine the relation between the sales of different alcoholic beverages and CVD mortality rates.Results. Vodka consumption as measured by sales was significantly associated with both male and female CVD mortality rates: a 1 liter increase in vodka sales would result in a 5.3% increase in the male CVD mortality rate and a 3.7% increase in the female rate. The consumption of beer and wine were not associated with CVD mortality rates.Conclusions. The findings from this study suggest that public health efforts should focus on both reducing overall consumption and changing beverage preference away from distilled spirits in order to reduce cardiovascular mortality rates in Russia.

scholarly journals Incidence, Prevalence, and Geographical Clustering of Motor Neuron Disease in the Netherlands

Neurology ◽  
2021 ◽  
Vol 96 (8) ◽  
pp. e1227-e1236
Author(s):  
Adriaan D. de Jongh ◽  
Ruben P.A. van Eijk ◽  
Susan M. Peters ◽  
Michael A. van Es ◽  
Anja M.C. Horemans ◽  
...  
Keyword(s):  
The Netherlands ◽  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Time Trends ◽  
Neuromuscular Diseases ◽  
Mortality Rates ◽  
Demographic Risk ◽  
Demographic Risk Factors ◽  
Age And Sex ◽  
Incidence Prevalence

ObjectiveTo assess time trends in motor neuron disease (MND) incidence, prevalence, and mortality and to investigate geographic clustering of MND cases in the Netherlands from 1998 to 2017, we analyzed data from the Netherlands Personal Records database, the Netherlands MND Center, and the Netherlands Patient Association of Neuromuscular Diseases.MethodsIn this prospective cohort study, Poisson regression was used to assess time trends in MND risk. We calculated age- and sex-standardized, observed, and expected cases for 1,694 areas. Bayesian smoothed risk mapping was used to investigate geographic MND risk.ResultsWe identified 7,992 MND cases, reflecting an incidence of 2.64 (95% confidence interval [CI] 2.62–2.67) per 100,000 person-years and a prevalence of 9.5 (95% CI 9.1–10.0) per 100,000 persons. Highest age-standardized prevalence and mortality rates occurred at a later age in men than in women (p < 0.001). Unadjusted mortality rates increased by 53.2% from 2.57 per 100,000 person-years in 1998 to 3.86 per 100,000 person-years in 2017. After adjustment for age and sex, an increase in MND mortality rate of 14.1% (95% CI 5.7%–23.2%, p < 0.001) remained. MND relative risk ranged from 0.78 to 1.43 between geographic areas; multiple urban and rural high-risk areas were identified.ConclusionsWe found a significant national increase in MND mortality from 1998 through 2017, explained only partly by an aging Dutch population, and a geographic variability in MND risk, suggesting a role for environmental or demographic risk factors.

scholarly journals Age-specific trends in cardiovascular mortality rates in Croatia between 1998 and 2012

2014 ◽  
Vol 9 (9-10) ◽  
pp. 417-417
Author(s):  
Verica Kralj ◽  
Mario Sekerija ◽  
Davor Plazanin
Keyword(s):  
Cardiovascular Mortality ◽  
Mortality Rates

scholarly journals Incidence, Survival, and Mortality Trends of Cancers Diagnosed in Adolescents and Young Adults (15–39 Years): A Population-Based Study in The Netherlands 1990–2016

Cancers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3421
Author(s):  
Daniël J. van der Meer ◽  
Henrike E. Karim-Kos ◽  
Marianne van der Mark ◽  
Katja K. H. Aben ◽  
Rhodé M. Bijlsma ◽  
...  
Keyword(s):  
The Netherlands ◽  
Cancer Patients ◽  
Cancer Incidence ◽  
Relative Survival ◽  
Mortality Rates ◽  
Adolescent And Young Adult ◽  
Mortality Trends ◽  
Netherlands Cancer Registry ◽  
Incidence And Mortality ◽  
Cancer Types

Adolescent and young adult (AYA) cancer patients, aged 15–39 years at primary cancer diagnosis, form a distinct, understudied, and underserved group in cancer care. This study aimed to assess long-term trends in incidence, survival, and mortality of AYA cancer patients within the Netherlands. Data on all malignant AYA tumours diagnosed between 1990–2016 (n = 95,228) were obtained from the Netherlands Cancer Registry. European age-standardised incidence and mortality rates with average annual percentage change (AAPC) statistics and five-year relative survival rates were calculated. The overall cancer incidence increased from 54.6 to 70.3 per 100,000 person-years (AAPC: +1.37%) between 1990–2016, and increased for both sexes individually and for most cancer types. Five-year relative survival overall improved from 73.7% in 1990–1999 to 86.4% in 2010–2016 and improved for both sexes and most cancer types. Survival remained poor (<60%) for rhabdomyosarcoma, lung, stomach, liver, bladder, and pancreatic carcinomas, among others. Mortality rates among male AYAs overall declined from 10.8 to 6.6 (AAPC: −1.64%) and from 14.4 to 10.1 per 100,000 person-years (AAPC: −1.81%) for female AYAs since 1990. Mortality rates remained unchanged for male AYAs aged 20–24 and 25–29 years. In conclusion, over the past three decades, there has been a considerable increase in cancer incidence among AYAs in the Netherlands. Meanwhile, the survival improved and the mortality overall declined. Survival at five-years now well exceeds above 80%, but did not do so for all cancer types.

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