scholarly journals An alginate–PHMB–AgNPs based wound dressing polyamide nanocomposite with improved antibacterial and hemostatic properties

2021 ◽  
Vol 32 (1) ◽  
Author(s):  
Laleh Asadi ◽  
Javad Mokhtari ◽  
Marjan Abbasi
Keyword(s):  
Water Uptake ◽  
Wound Dressing ◽  
Culture Media ◽  
Substrate Surface ◽  
Antibacterial Properties ◽  
Wound Dressings ◽  
Diffusion Method ◽  
Potential Candidate ◽  
Uptake Capacity ◽  
Water Uptake Capacity

AbstractWound dressing should be impenetrable against microorganisms and it should keep the wound wet. Gauze and polyamide (PA) substrate were treated with various concentrations of AgNPs (25, 50, 75, and 100 ppm), PHMB (0.2, 0.4, 0.6, 0.8, and 1% w/v), and constant concentration of alginate (0.5% W/V) using a simple dipping method. Prepared samples were characterized by various techniques including Fourier transform infrared spectroscopy and scanning electron microscopy. The results indicated that the particles were successfully applied onto both substrates with an average diameter of particle size of 78 nm on gauze and 172 nm on the PA substrate surface (based on 50 nanoparticles). Antibacterial activity of the prepared nanocomposite against Staphylococcus aureus (gram-positive) bacteria on PA substrate and gauze were evaluated using the disc diffusion method. The results indicated that the prepared nanocomposites offer favorable antibacterial properties and bacteria would not grow in culture media. The water uptake capacity test of the treated samples was assessed and the data demonstrated that the water absorption rate significantly increases on both treated substrates (gauze and PA substrate) due to the presence of alginate polymer. Also, observing the results of the coagulation test showed that treated samples caused blood clots on the dressing. This is due to the presence of alginate polymer. The present work demonstrates that the prepared samples offer excellent antibacterial properties and good water uptake capacity that capable of being a potential candidate for wound dressings. Due to the results, the produced PA substrate could be an appropriate replacement for the cotton gauze as a wound dressing.

Fabrication of bioactive glass-introduced nanofibrous membranes with multifunctions for potential wound dressing

RSC Advances ◽  
2014 ◽  
Vol 4 (104) ◽  
pp. 60114-60122 ◽  
Author(s):  
Weibin Ma ◽  
Xianyan Yang ◽  
Liang Ma ◽  
Xingang Wang ◽  
Lei Zhang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Bioactive Glass ◽  
Water Uptake ◽  
Wound Dressing ◽  
Chronic Wound ◽  
Uptake Capacity ◽  
Water Uptake Capacity ◽  
Nanofibrous Membranes

Bioactive glass-introduced gelatin/chitosan nanofibrous dressings were developedviaelectrospinning to endow improved antibacterial activity, adjustable bioactivity and water uptake capacity for enhancing chronic wound healing.

scholarly journals Strengthening of Porcine Plasma Protein Superabsorbent Materials through a Solubilization-Freeze-Drying Process

Polymers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 772
Author(s):  
Estefanía Álvarez-Castillo ◽  
Carlos Bengoechea ◽  
Antonio Guerrero
Keyword(s):  
Water Uptake ◽  
Plasma Protein ◽  
Freeze Drying ◽  
Meat Industry ◽  
Drying Process ◽  
Uptake Capacity ◽  
Water Uptake Capacity ◽  
Protein Flour ◽  
Hydrophilic Materials ◽  
By Products

The replacement of common acrylic derivatives by biodegradable materials in the formulation of superabsorbent materials would lessen the associated environmental impact. Moreover, the use of by-products or biowastes from the food industry that are usually discarded would promote a desired circular economy. The present study deals with the development of superabsorbent materials based on a by-product from the meat industry, namely plasma protein, focusing on the effects of a freeze-drying stage before blending with glycerol and eventual injection molding. More specifically, this freeze-drying stage is carried out either directly on the protein flour or after its solubilization in deionized water (10% w/w). Superabsorbent materials obtained after this solubilization-freeze-drying process display higher Young’s modulus and tensile strength values, without affecting their water uptake capacity. As greater water uptake is commonly related to poorer mechanical properties, the proposed solubilization-freeze-drying process is a useful strategy for producing strengthened hydrophilic materials.

Synthesis and characterization of poly(glycerol sebacate)-based elastomeric copolyesters for tissue engineering applications

2016 ◽  
Vol 7 (14) ◽  
pp. 2553-2564 ◽  
Author(s):  
Yating Jia ◽  
Weizhong Wang ◽  
Xiaojun Zhou ◽  
Wei Nie ◽  
Liang Chen ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Water Uptake ◽  
Synthesis And Characterization ◽  
Uptake Capacity ◽  
Engineering Applications ◽  
Water Uptake Capacity

A poly(glycerol sebacate)-based elastomeric copolyesters with improved mechanical properties and higher water uptake capacity.

scholarly journals Antibacterial-Integrated Collagen Wound Dressing for Diabetes-Related Foot Ulcers: An Evidence-Based Review of Clinical Studies

Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2168
Author(s):  
Ibrahim N. Amirrah ◽  
Mohd Farhanulhakim Mohd Razip Wee ◽  
Yasuhiko Tabata ◽  
Ruszymah Bt Hj Idrus ◽  
Abid Nordin ◽  
...  
Keyword(s):  
Wound Healing ◽  
Clinical Trials ◽  
Clinical Studies ◽  
Wound Dressing ◽  
Chronic Wounds ◽  
Gentian Violet ◽  
Antibacterial Properties ◽  
Small Sample ◽  
Wound Dressings ◽  
Sample Sizes

Diabetic foot ulcer (DFU) is a chronic wound frequently delayed from severe infection. Wound dressing provides an essential barrier between the ulcer and the external environment. This review aimed to analyse the effectiveness of antibacterial collagen-based dressing for DFU treatment in a clinical setting. An electronic search in four databases, namely, Scopus, PubMed, Ovid MEDLINE(R), and ISI Web of Science, was performed to obtain relevant articles published within the last ten years. The published studies were included if they reported evidence of (1) collagen-based antibacterial dressing or (2) wound healing for diabetic ulcers, and (3) were written in English. Both randomised and non-randomised clinical trials were included. The search for relevant clinical studies (n) identified eight related references discussing the effectiveness of collagen-based antibacterial wound dressings for DFU comprising collagen impregnated with polyhexamethylene biguanide (n = 2), gentamicin (n = 3), combined-cellulose and silver (n = 1), gentian violet/methylene blue mixed (n = 1), and silver (n = 1). The clinical data were limited by small sample sizes and multiple aetiologies of chronic wounds. The evidence was not robust enough for a conclusive statement, although most of the studies reported positive outcomes for the use of collagen dressings loaded with antibacterial properties for DFU wound healing. This study emphasises the importance of having standardised clinical trials, larger sample sizes, and accurate reporting for reliable statistical evidence confirming DFU treatment efficiency.

Fabrication and optimization of PCL/PVP nanofibers with Lawsonia inermis for antibacterial wound dressings

2021 ◽  
Vol 29 (9_suppl) ◽  
pp. S1403-S1413
Author(s):  
Mehdi Varsei ◽  
Nadia Rahimi Tanha ◽  
Mohsen Gorji ◽  
Saeedeh Mazinani
Keyword(s):  
Wound Dressing ◽  
Mechanical Performance ◽  
Polymer Concentration ◽  
Antibacterial Properties ◽  
Wound Dressings ◽  
Gram Negative Bacteria ◽  
Lawsonia Inermis ◽  
Accelerate Wound Healing ◽  
Hydrophobic Polymer ◽  
Surface Method

Anti-infection ability and desirable air permeability (AP) are the important aspects of wound dressings that should be regulated with regard to primary polymers and antibacterial agents. This study aims to fabricate and optimize a wound dressing with antibacterial properties. For this purpose, polycaprolactone (PCL) as a hydrophobic polymer and polyvinylpyrrolidone (PVP) as a hydrophilic polymer were electrospun with Lawsonia inermis (Henna) extract as an antibacterial component based on the experiments proposed by Design-Expert software. The morphology and properties of the wound dressing were studied by scanning electron microscopy, Fourier transform infrared, and AP. The response surface method (RSM) was used to determine the optimal fiber diameter and AP of the samples as a function of the polymer concentration and feed rate. The optimal PCL/PVL/Henna wound dressing has antibacterial properties against Gram-positive and Gram-negative bacteria while being biocompatible according to the MTT assay. These fibrous structures can be used as a wound dressing to prevent infection and accelerate wound healing; thanks to proper Henna release, breathability, swelling ratio, and mechanical performance.

Enhanced stability and water solubilizing capacity of water-in-oil microemulsions based on protic ionic liquids

2017 ◽  
Vol 19 (38) ◽  
pp. 26132-26144 ◽  
Author(s):  
Akhil Pratap Singh ◽  
Kaushik Kundu ◽  
Vikram Singh ◽  
Ramesh L. Gardas ◽  
Sanjib Senapati
Keyword(s):  
Thermal Stability ◽  
Ionic Liquids ◽  
Water Uptake ◽  
Protic Ionic Liquids ◽  
Uptake Capacity ◽  
Water Uptake Capacity ◽  
Solubilizing Capacity ◽  
Thermal Stability Of ◽  
Enhanced Stability

In view of this limited research on pILs in microemulsions, here we study the formation and characterization of a series of pIL–water/oil microemulsions with specific questions on the effect of pILs on water uptake capacity and thermal stability of W/O microemulsions.

Termination of swelling capacity of smectites by Cutrien exchange

Clay Minerals ◽  
2011 ◽  
Vol 46 (3) ◽  
pp. 411-420 ◽  
Author(s):  
S. Kaufhold ◽  
R. Dohrmann ◽  
K. Ufer ◽  
R. Kleeberg ◽  
H. Stanjek
Keyword(s):  
Water Uptake ◽  
X Ray Diffraction ◽  
Interlayer Water ◽  
Uptake Capacity ◽  
Fe Content ◽  
Water Uptake Capacity ◽  
Swelling Capacity ◽  
Adsorption Processes ◽  
Interlayer Region

AbstractThe Cu-triethylenetetramine-complex (Cutrien) is one of the commonly used index cations for CEC determination in clay science. Cutrien-exchanged smectites show basal spacings between 13.0 and 13.5 Å after correction for the Lorentz and polarization factors. The full width at half maximum (FWHM) of the d001 reflection is today related to the percentage of tetrahedral charge (beidellitic character) and/or to the Fe content of the smectites. The structural Fe content and the tetrahedral charge correlate, so their individual influence on d001 cannot be resolved. Nevertheless, the FWHM of Cutrien smectites should depend on the charge distribution rather than the Fe content.X-ray diffraction (XRD) and water uptake capacity measurements showed that the interlayer of Cutrien-exchanged smectites does not swell any more, but can take up a few water molecules. Accordingly, the water uptake capacity of the external surface area can be determined independently from the interlayer water uptake capacity. Adjusting the pH of Cutrien-bentonite dispersion to different values allows for the determination of the variable charge.In conclusion, Cutrien exchange of smectites appears to be suitable for the study of external surfaces area related phenomena (e.g. edge adsorption processes) without any influence of the interlayer region.

A significant enhancement of water vapour uptake at low pressure by amine-functionalization of UiO-67

2015 ◽  
Vol 44 (5) ◽  
pp. 2047-2051 ◽  
Author(s):  
Nakeun Ko ◽  
Jisu Hong ◽  
Siyoung Sung ◽  
Kyle E. Cordova ◽  
Hye Jeong Park ◽  
...  
Keyword(s):  
Water Vapour ◽  
Water Uptake ◽  
Metal Organic Framework ◽  
Significant Enhancement ◽  
Relative Pressure ◽  
Amine Functionalization ◽  
Uptake Capacity ◽  
Water Uptake Capacity ◽  
Metal Organic ◽  
Water Vapour Uptake

The functionalization of the metal–organic framework, UiO-67, with –NH2 groups is proven effective for increasing the water uptake capacity at low relative pressure at 298 K.

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