An exhaustive yet simple virtual screening campaign against Sortase A from multiple drug resistant Staphylococcus aureus

2014 ◽  
Vol 41 (8) ◽  
pp. 5167-5175
Author(s):  
Reaz Uddin ◽  
Kiran Saeed
Keyword(s):  
Staphylococcus Aureus ◽  
Virtual Screening ◽  
Multiple Drug ◽  
Sortase A ◽  
Drug Resistant ◽  
Multiple Drug Resistant

scholarly journals Studies on the effects of 3-acetyl-4"-isovaleryltylosin against multiple-drug resistant strains of Staphylococcus aureus.

1981 ◽  
Vol 34 (3) ◽  
pp. 305-312 ◽  
Author(s):  
MASAMI TSUCHIYA ◽  
KAYOKO SUZUKAKE ◽  
MAKOTO HORI ◽  
TSUTOMU SAWA ◽  
TOMIO TAKEUCHI ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Multiple Drug ◽  
Drug Resistant ◽  
Multiple Drug Resistant ◽  
Resistant Strains ◽  
Drug Resistant Strains

An Antibacterial Nanorobotic Approach for the Specific Targeting and Removal of Multiple Drug‐Resistant Staphylococcus aureus

Small ◽  
2021 ◽  
pp. 2100257
Author(s):  
Nayab Batool ◽  
Seokyoung Yoon ◽  
Saba Imdad ◽  
Minsuk Kong ◽  
Hun Kim ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Multiple Drug ◽  
Drug Resistant ◽  
Specific Targeting ◽  
Multiple Drug Resistant

In vitro evaluation of antibacterial potential of Andrographis paniculata against resistant bacterial pathogens methicillin resistant Staphylococcus aureus (MRSA) and multiple drug resistant Escherichia coli (MDR E. coli)

2016 ◽  
Vol 5 (03) ◽  
pp. 4879
Author(s):  
Srikala Ganapathy* ◽  
Karpagam S.
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Antibacterial Agents ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Ethanolic Extract ◽  
Multiple Drug ◽  
Drug Resistant ◽  
E Coli ◽  
Multiple Drug Resistant

Rise of antibiotic resistant pathogenic bacteria namely Methicillin Resistant Staphylococcus aureus (MRSA) and Multiple drug resistant Escherichia coli (MDR E. coli results in reduced efficacy of currently used antibacterial agents. Medicinal plants serve as potential targets for biologically effective antibacterial agents. The present study determined the phytochemical and invitro antibacterial activity of ethanol, chloroform, hexane and water extracts of whole plant of Andrographis paniculata against MRSA and MDR Escherichia coli. Zone of inhibition diameters were measured. Compared to all the extracts, ethanolic extract showed highest activity. The antibacterial activity was absent in hexane and water extracts. Chloroform extracts showed moderately good activity. The antibacterial compounds found in ethanolic extract were flavanoids, saponins and alkaloids.

scholarly journals Multiple drug resistant Staphylococcus aureus strains isolated from a fish market and from fish handlers

2007 ◽  
Vol 38 (1) ◽  
pp. 131-134 ◽  
Author(s):  
W.F. Albuquerque ◽  
A. Macrae ◽  
O.V. Sousa ◽  
G.H.F. Vieira ◽  
R.H.S.F. Vieira
Keyword(s):  
Staphylococcus Aureus ◽  
Multiple Drug ◽  
Drug Resistant ◽  
Fish Market ◽  
Multiple Drug Resistant

Highly Virulent Pathogens - a Post Antibiotic Era?

1998 ◽  
Vol 8 (2) ◽  
pp. 14-18 ◽  
Author(s):  
Michael A Domin
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Resistance ◽  
Infection Control ◽  
Multiple Drug Resistance ◽  
Infection Prevention And Control ◽  
Multiple Drug ◽  
Drug Resistant ◽  
Multiple Drug Resistant ◽  
Resistant Strains ◽  
Vancomycin Resistant

The spectrum of infectious diseases is changing rapidly. Emerging infectious agents present an intriguing constellation of nosocomial challenges. Antimicrobial resistance results in increased morbidity, mortality and costs of health care. Resistance to antimicrobial agents has been recorded since 1940 with penicillin resistant Escherichia coli (E coli) (Abraham and Chain 1940). A similar pencillin resistance was reported in 1944 in Staphylococus aureus (S. aureus) (Kirby 1944) Even before the widespread global use of penicillin, resistance had already been detected in both grampositive and gram-negative organisms. The 1990s herald the era of multiple drug resistance. To grasp further the enormity and complexity of our modern antimicrobial resistance problem, one only needs to think about how many - how fast -and in how many settings (hospitals, clinics, outpatients nursing and long term facilities, etc), these pathogens have developed antimicrobial resistance: Multiple drug-resistant Mycobacterium tuberculosis, penicillin-resistant Streptococcus pneumonia, fluconzole-resistant Candida, methicillin-resistant S. aureus (MRSA), vancomycin-resistant Enterococci (VRE) and now S. aureus with reduced susceptibility to vancomycin. Given the dramatic increase in the incidence of multiple drug-resistant organisms - and now - the mounting evidence of resistance transfer from one organism to another, we will certainly witness a combined growth of nosocomial pathogens, for which there are no antibiotic solutions. Appropriate infection control measures for such resistant strains depend, in part, on the mechanisms of genetic information exchanged among micro-organisms. Clearly we need to strengthen the basic tenets of infection prevention and control; hygiene, engineering and microbial barriers, to prevent transinfection. We need to control horizontal nosocomial transmission of organisms. Contaminated environmental surfaces are a reservoir for resistant organisms such as MRSA (Boyce et al 1997) and VRE (Karanfil et al 1992). Stringent infection control policies need to be developed and implemented. A comprehensively applied infection control programme will reduce the dissemination of resistant strains. Each patient care setting must examine its current practices and review the outcome efficacy. A consensus development conference to develop centres for disease control (CDC) formal guidelines against vancomycin intermediate-level resistant staphylococcus aureus (VISA) and vancomycin-resistant staphylococcus aureus (VRSA) may take a year or more to convene. This paper will examine the basic considerations currently offered by the CDC which may be valuable starting points for the enhancement of current infection control practices. Perspectives of the Society for Healthcare Epidemiology of America (SHEA) will also be included.

scholarly journals High Prevalence of Multiple Drug Resistant and Biofilm Forming Staphylococcus aureus among HIV-Infected Patients with Suspected Pneumonia

2018 ◽  
Vol 12 (4) ◽  
pp. 1905-1912
Author(s):  
Ravish Katiyar ◽  
Shilpa Kaistha ◽  
Neena Srivastava ◽  
Sandeep Chowdhary ◽  
Atul Garg ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Multiple Drug ◽  
Drug Resistant ◽  
Multiple Drug Resistant ◽  
High Prevalence ◽  
Suspected Pneumonia
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