Effect of different levels of dietary nitrogen supplementation on the relative blood urea nitrogen concentration of beef cows

Acetaminophen also called paracetamol is commonly used as analgesic and antipyretic agent which in high doses causes liver and kidney damage in man and animals. Nigella sativa oil have antioxidant properties. Thirty adult male rats were used and randomly divided into three equal groups. Group (A) untreated and served as control group; Group (B) rats were orally intubated (by gavages needle) acetaminophen suspension (150mg/kg B.W). Group (C) rats were given orally acetaminophen suspension (150mg/kg) plus 1ml/kg B.W of Nigella sativa oil for 42 days in both treated group. Fasting blood samples were collected at 21 and 42 days of experiment to study the following parameters: Serum creatinine concentration and blood urea nitrogen concentration. The results revealed a significant increase of acetaminophen group in serum creatinine and blood urea nitrogen concentrations as compression with GA. Animals treated with Nigella sativa oil plus acetaminophen (C) showed a significant decline in serum creatinine and blood urea nitrogen concentrations. In conclusion, the acetaminophen was effective in induction of oxidative stress and change in some biological markers related to kidney disease. Also it seems that Nigella sativa oil exerts protective actions against the damaging effect of acetaminophen

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Pemberian Minuman dan Cookies Galohgor Terhadap Kadar Blood Urea Nitrogen (Bun) dan Kreatinin Plasma Penderita Diabetes Melitus Tipe 2

JURNAL GIZI DAN KESEHATAN ◽

10.35473/jgk.v12i1.75 ◽

2020 ◽

Vol 12 (1) ◽

pp. 1-10

Author(s):

Laeli Nur hasanah ◽

Katrin Roosita ◽

Rimbawan

Keyword(s):

Blood Urea Nitrogen ◽

Randomized Control Trial ◽

Control Group ◽

Post Intervention ◽

Urea Nitrogen ◽

Randomized Control ◽

Single Blind ◽

Type 2 Diabetic ◽

Different Levels

The aim of this research was to analyze the effect of drinks and cookies contained Galohgor extract on Blood Urea Nitrogen (BUN) and creatinine plasma in type 2 diabetic subjects. This study used single blind Randomized Control Trial (RCT) with cross-over design applied on 11 type 2 diabetic subjects in Cikarawang, Babakan and Balumbang Jaya Village-Dramaga, Bogor District, West Java. Each subject received powdered drinks and cookies contained Galohgor extract 2 grams/day (1 gram of Galohgor extract in the form of drink 8 grams and 1 gram of Galohgor extract in the form of cookies 24 grams) and without Galohgor extract (control) for 38 days treatment with four wash-out period between treatment periods. BUN and creatinine levels were conducted by plasma blood sample at pre and post intervention. The result showed that the different levels of BUN between post and pre intervention for Galohgor group compared to control group were -4,9±11,2 mg/dL and -9,6±12,5 mg/dL (p>0,05). The different levels of creatinine between post and pre intervention for Galohgor group compared to control group were -0,1±0,2 mg/dL and -0,1±0,2 mg/dL (p>0,05). Therefore, drinks and cookies contained Galohgor extract 2 gram/day does not affect the BUN and creatinine level of type 2 diabetic subjects. Abstrak : Penelitian ini bertujuan untuk menganalisis pengaruh minuman dan cookies Galohgor terhadap kadar Blood Urea Nitrogen (BUN) dan kadar kreatinin plasma penderita DM tipe 2. Jenis penelitian ini adalah single blind Randomized Control Trial (RCT) dengan desain cross-over pada 11 subjek DM tipe 2 yang dilakukan di desa Cikarawang, Babakan dan Balumbang Jaya, Kecamatan Dramaga, Kabupaten Bogor, Jawa Barat. Masing-masing subjek mendapatkan minuman dan cookies yang mengandung ekstrak Galohgor sebesar 2 gram/hari (1 gram ekstrak Galohgor dalam bentuk 8 gram minuman serbuk dan 1 gram ekstrak Galohgor dalam bentuk 24 gram cookies) dan minuman serbuk dan cookies tanpa ekstrak Galohgor (kontrol) selama 38 hari dengan empat bulan periode wash-out antar perlakuan. Kadar BUN dan kreatinin dikumpulkan dari sampel plasma darah pada sebelum dan setelah intervensi. Hasil penelitian menunjukkan rata-rata selisih kadar BUN pada kelompok Galohgor dibandingkan dengan kelompok kontrol yaitu -4,9±11,2 mg/dL dan -9,6±12,5 mg/dL (p>0,05). Kadar kreatinin pada kelompok Galohgor dibandingkan dengan kelompok Galohgor yaitu -0,1±0,2 mg/dL dan -0,1±0,2 mg/dL (p>0,05). Oleh karena itu, pemberian minuman dan cookies yang mengandung ekstrak Galohgor 2 gram/hari tidak berpengaruh terhadap kadar ureum dan kreatinin penderita DM tipe 2.

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The Synergistic Effect of Microwave Radiation and Hypergravity on Rats and the Intervention Effect of Rana Sylvatica Le Conte Oil

Dose-Response ◽

10.1177/1559325817711511 ◽

2017 ◽

Vol 15 (2) ◽

pp. 155932581771151 ◽

Cited By ~ 1

Author(s):

Wei Sun ◽

Yudan Yang ◽

Hongmei Yu ◽

Luowei Wang ◽

Su Pan

Keyword(s):

Synergistic Effect ◽

Antioxidant Capacity ◽

Microwave Radiation ◽

Blood Urea Nitrogen ◽

Total Antioxidant Capacity ◽

Nitrogen Concentration ◽

Rana Sylvatica ◽

Urea Nitrogen ◽

Choline Acetyl Transferase ◽

Total Antioxidant

Aim: The phenomena of hypergravity and microwave radiation are widespread, which cause more and more concern for the hazards to human health. The aim of this study was to investigate the synergistic effect of microwave radiation and hypergravity on rats and observe the protective effect of Rana sylvatica Le conte oil. Methods: Rats were exposed to microwave radiation and hypergravity, and the rat weight, the climbing pole height, serum enzyme activities, blood urea nitrogen concentration, and total antioxidant capacity were detected. Results: The climbing pole height, the activities of choline acetyl transferase and cholinesterase, and the total antioxidant capacity decreased, whereas the activities of alanine aminotransferase, aspartate aminotransferase, areatine kinase, isocitric dehydrogenase, hydroxybutyrate dehydrogenase, and the blood urea nitrogen concentration increased in the hypergravity irradiation group as compared with the others. Conclusion: These results imply that the motion and nervous system of rats might be affected critically by the synergistic effect of microwave radiation and hypergravity, and it causes damage to most rat organs, such as the bone, skeletal muscle, liver, heart, and kidney, and the antioxidant effect is also damaged, while the injury resulted from it could be protected by Rana sylvatica Le conte oil.

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PSXVI-36 Factors influencing blood urea nitrogen concentration in Angus cattle.

Journal of Animal Science ◽

10.1093/jas/sky404.842 ◽

2018 ◽

Vol 96 (suppl_3) ◽

pp. 384-384

Author(s):

S Speidel ◽

M Culbertson ◽

M Sanchez-Castro ◽

K Sellins ◽

T Engle ◽

...

Keyword(s):

Blood Urea Nitrogen ◽

Nitrogen Concentration ◽

Urea Nitrogen ◽

Angus Cattle ◽

Factors Influencing

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The effect of dietary content of plant protein on the utilization of urea in the bovine rumen

British Journal Of Nutrition ◽

10.1079/bjn19710031 ◽

1971 ◽

Vol 26 (2) ◽

pp. 237-247 ◽

Cited By ~ 4

Author(s):

J. Anna Nikolić ◽

M. Jovanović ◽

D. Stošić ◽

A. Pavličević

Keyword(s):

Nitrogen Concentration ◽

Latin Square ◽

High Protein ◽

Urea Nitrogen ◽

Plant Nitrogen ◽

Dietary Nitrogen ◽

Rumen Ph ◽

Total Nitrogen Concentration ◽

Negative Effect ◽

True Protein

1. Four young Friesian bulls with rumen fistulas were given four isocaloric all-concentrate diets containing different amounts and sources of nitrogen in a Latin square arrangement. Diet HP (high-protein) contained 2·31% plant nitrogen; diet MPU (medium-protein with urea) 1·67% plant nitrogen and 0·69% urea nitrogen (total 2·36%); diet LPU (low-protein with urea) 0·95% plant nitrogen and 0·69% urea nitrogen (total 1·65%); diet HPU (high-protein with urea) 2·28% plant nitrogen and 0·69% urea nitrogen (total 2·97%), calculated on an air-dry basis.2. The rumen pH varied between 5·8 and 6·1 with diets HP, MPU and HPU, but was significantly lower with diet LPU with values between 5·4 and 5·8.3. The results showed no differences between the isonitrogenous diets HP and MPU except that replacement of plant nitrogen with urea was followed by an increase in the concentration of ammonia in the rumen. With the diets containing urea, the concentrations of rumen ammonia varied inversely with the amount of dietary plant nitrogen supplied, indicating a negative effect of plant nitrogen on urea utilization.4. Concentrations of alkali-labile nitrogen (amide) were not increased with diets containing urea except with diet HPU, which produced the highest concentrations of ammonia in the rumen.5. The concentration of true protein in the rumen and the amino acid distribution were similar with all four diets, indicating the ability of the microflora to adapt to qualitative and quantitative differences in dietary nitrogen intake.6. Ration acceptability was lower with diets LPU and HPU than with diets HP and MPU.7. Large differences between individual animals in rumen pH, percentage of dry matter and total nitrogen concentration in the rumen were noted.

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