Estimating the future clinical and economic benefits of improving osteoporosis diagnosis and treatment among women in Japan: a simulation projection model from 2020 to 2040

Aim of this letter is to attract the attention of journal readers to the study of exosomes as an important direction in the development of Oncology, in particular, in the diagnosis and treatment of prostate cancer. Exosomes are produced by tumor cells and regulate proliferation, metastasis, and the development of chemoresistance. Their extraction from biological fluids allows further use of these vesicles as potential biomarkers of prostate cancer. In the future, exosomes can be successfully used in the delivery of drugs and other anti-tumor substances to cancer cells.

Download Full-text

Characteristics of Asian Mosquito Saliva Allergens for Specific Diagnoses and Effective Therapies

Current Protein and Peptide Science ◽

10.2174/1389203720666190729122614 ◽

2020 ◽

Vol 21 (2) ◽

pp. 153-158 ◽

Cited By ~ 1

Author(s):

Soung-Hoo Jeon

Keyword(s):

Allergic Reaction ◽

East Asia ◽

East Asian ◽

Diagnosis And Treatment ◽

Recombinant Allergens ◽

Systemic Reactions ◽

The Future ◽

Mosquito Saliva ◽

The Difference ◽

Future Direction

An allergic reaction to mosquitoes can result in severe or abnormal local or systemic reactions such as anaphylaxis, angioedema, and general urticarial or wheezing. The aim of this review is to provide information on mosquito saliva allergens that can support the production of highly specific recombinant saliva allergens. In particular, candidate allergens of mosquitoes that are well suited to the ecology of mosquitoes that occur mainly in East Asia will be identified and introduced. By doing so, the diagnosis and treatment of patients with severe sensitivity to mosquito allergy will be improved by predicting the characteristics of East Asian mosquito allergy, presenting the future direction of production of recombinant allergens, and understanding the difference between East and West.

Download Full-text

The Market Valuation of Environmental Capital Expenditures by Pulp and Paper Companies

The Accounting Review ◽

10.2308/accr.2004.79.2.329 ◽

2004 ◽

Vol 79 (2) ◽

pp. 329-353 ◽

Cited By ~ 233

Author(s):

Peter M. Clarkson ◽

Yue Li ◽

Gordon D. Richardson

Keyword(s):

Environmental Performance ◽

Capital Expenditure ◽

Paper Industry ◽

Pulp And Paper Industry ◽

Economic Benefits ◽

Pulp And Paper ◽

Market Valuation ◽

The Future ◽

Environmental Capital ◽

Polluting Firms

The objective of this study is to examine the market valuation of environmental capital expenditure investment related to pollution abatement in the pulp and paper industry. The total environmental capital expenditure of $8.7 billion by our sample firms during 1989–2000 supports the focus on this industry. In order to be capitalized, an asset should be associated with future economic benefits. The existing environmental literature suggests that investors condition their evaluation of the future economic benefits arising from environmental capital expenditure on an assessment of the firms' environmental performance. This literature predicts the emergence of two environmental stereotypes: low-polluting firms that overcomply with existing environmental regulations, and high-polluting firms that just meet minimal environmental requirements. Our valuation evidence indicates that there are incremental economic benefits associated with environmental capital expenditure investment by low-polluting firms but not high-polluting firms. We also find that investors use environmental performance information to assess unbooked environmental liabilities, which we interpret to represent the future abatement spending obligations of high-polluting firms in the pulp and paper industry. We estimate average unbooked liabilities of $560 million for high-polluting firms, or 16.6 percent of market capitalization.

Download Full-text

Exploring The Viability of Dams is Key to Malaysian Water Resources Development of the Future

The Journal of The Institution of Engineers, Malaysia ◽

10.54552/v76i1.40 ◽

2015 ◽

Vol 76 (1) ◽

Author(s):

Dato’ Ir. Syed Muhammad Shahabudin

Keyword(s):

Water Resources ◽

Flood Control ◽

River Flow ◽

Economic Benefits ◽

Conservation Strategies ◽

Water Resources Development ◽

The Public ◽

The Future ◽

Control Water ◽

Resources Development

It is said tluit civilization began and prospered when humans could control water; and that same civilization declined and vanished when that control is lost. Dams and other river flow barriers were built to harness and control water in the early days of civilisation in order to secure the benefits for human basic needs and comfort. Centuries later, more dams were built to cater for increasing population, especially in arid and semi-arid areas. But it is really in the past two centuries that many large-sized dams have been built to satisfy a wider range of development demands — hydropower, treated water supply, irrigation, flood control and environmental needs.Towards the second half of the last century, society came to realise that dams can cause significant negative social and environmental impacts that could outweigh the original economic benefits. Opponents of dams protest vehemently world-wide against the development of more dams whilst proponents are convinced tluit the y are a necessary feature to support growth and prosperity. It is these contradicting beliefs in mind tluit the public must be engaged to facilitate a better understanding of the views of both the proponents and the opponents of dam development before deciding on a long-term strateg y. In the meantime, more effort may have to be made for water and energ y conservation strategies and to realize the potential applications of low impact and non-structural solutions that complement existing dams and defer new dam development to as far into the future as possible.This paper aims to provoke a critical debate amongst engineers and the public to look at the longer term future ofdams in water resources development that could possibl y reduce the fundamental demand for services that dam provides. In other words, to try and answer the question “Why should a country rich in water, as Malaysia is, need to construct dams and even plan for more?”

Download Full-text

Regulation of Lifelong in Education and İts Economic, Social Benefits

Turkish Journal of Computer and Mathematics Education (TURCOMAT) ◽

10.17762/turcomat.v12i6.2470 ◽

2021 ◽

Vol 12 (6) ◽

pp. 1298-1310

Author(s):

Allahyar Muradov Et al.

Keyword(s):

Human Capital ◽

Social Problems ◽

Labour Productivity ◽

Economic Benefits ◽

Social Benefits ◽

Development Economic ◽

Knowledge Based ◽

The Future ◽

The Impact

Sustainability in education is important in ensuring knowledge-based and innovation-driven development and human capital reproduction. Sustainability is particular important for the prevention of some economic and social problems that may arise in the future and raising the competitiveness of the country. Sustainability - the prevention as some of economic and social problems that may arise in the future is of particular importance in raising the country's competitiveness. The aim of the research is to estimate the economic-social benefits of regulation of sustainability in education and to give the suggestions in the direction of the improvement of the effectiveness of the regulation. The impact of continuity in education on the formation and development of human capital, knowledge-based society building, labour intelligence, competitiveness and the improvement of welfare are assessed cross-country in the article. In particular, in recent years, researches and politicians have analysed the ‘4th industry’ revolution (‘Industry 4.0’) ‘the benefits and losses in the medium and long-term perspective and its interaction with the sustainability of education. Here are two issues: 1) socioeconomic disadvantages of ensuring sustainability in education, 2) socioeconomic advantages of ensuring sustainability in education. Firstly, it is analysed the impacts of increased unemployment, reduction of employment income, declining social security and welfare that will be resulted as problems on economic development. Secondly, it is analysed (ensuring in sustainability condition) the distinguished factors of rapid technological innovation, labour productivity, repatriation of human capital, raising competitiveness on the international level, innovation-based development, economic benefits of knowledge and skills.

Download Full-text