scholarly journals Objective Evaluation of Olfactory and Taste Dysfunction Among COVID-19 Patients: A Cross Sectional Study from Tribal India

Author(s):  
Izhar Khan ◽  
Vikas Gupta ◽  
Sanjay Kumar Shukla
2021 ◽  
Vol 10 (1) ◽  
pp. 17-23
Author(s):  
Maryam Mirmotalebi ◽  
◽  
Behshid Garrusi ◽  
Mina Danaei

Background and Objective: Evaluation of the severity of pain in children can help the medical team diagnose the type of disease. In this study, anxiety and pain intensity in children were examined based on self-report. Materials and Methods: This cross-sectional study was performed in 2018 on 300 children aged 3 to 12 years, referring to outpatient treatment centres in Kerman. To measure the severity of pain felt by children, FPS-R was used. The level declared by children was evaluated by the pain intensity estimated by parents and doctors using a visual analogue scale (VAS) and the standard FLACC (Face, Legs, Activity, Cry, Consolability scale) for correlation. The data were analysed using SPSS software version 25. Results: The pain reported by children was obtained by VAS (4.16 ± 3.49), and the estimated pain by the doctor was obtained by FPS-R (2.87±1.68). The pain severity estimated by the doctor using FLACC had the highest correlation with the pain estimated by the doctor using VAS and the lowest correlation with the pain estimated by the mother using VAS. Conclusion: The results of this study showed that FPS-R could be used as a suitable self-report tool in children and, along with the standard FLACC, can help the medical team recognize the severity of children's pain.


e-GIGI ◽  
2013 ◽  
Vol 1 (2) ◽  
Author(s):  
Made Ary Prawira

Pasien yang menjalani kemoterapi seringkali mengalami masalah pada rongga mulutnya. Hal ini bisa disebabkan karena agen kemoterapi pada umumnya menyebabkan efek destruktif langsung pada jaringan sekitar rongga mulut dan juga secara tidak langsung dengan menginduksi myelosupresi dan imunosupresi. Komplikasi oral yang banyak dijumpai pada pasien yang menjalani kemoterapi ialah mukositis oral, kandidiasis, xerostomia, gangguan pengecapan dan perdarahan. Tujuan dari penelitian ini yaitu untuk mengetahui gambaran komplikasi oral yang terjadi pada pasien yang menjalani kemoterapi di Badan Layanan Umum RSUP Prof. Dr. R. D. Kandou Manado serta angka kejadian dari komplikasi oral tersebut berdasarkan umur, jenis kelamin, jenis kemoterapi, lama kemoterapi serta jenis kanker yang dialami oleh pasien tersebut. Jenis penelitian ini ialah penelitian deskriptif dengan desain cross sectional study. Pengambilan sampel dilakukan dengan teknik purposive sampling dengan jumlah sampel 64 yang didapat berdasarkan rumus Cochran. Hasil penelitian menunjukkan bahwa xerostomia dan mukositis oral merupakan komplikasi oral yang paling banyak dialami pasien setelah menjalani kemoterapi dengan angka kejadian lebih dari 60%. Sedangkan komplikasi oral lain seperti kandidiasis, gangguan pengecapan dan perdarahan memiliki angka kejadian lebih dari 25%. Dari hasil penelitian, disarankan kepada para klinisi harus lebih memperhatikan berbagai macam komplikasi oral yang timbul pada pasien yang menjalani kemoterapi. Kerja sama yang baik antara pasien, dokter gigi dan oncologist sangat penting dilakukan untuk meminimalisir angka kejadian komplikasi oral yang ditimbulkan akibat perawatan kemoterapi.Kata kunci: Pasien yang menjalani kemoterapi, komplikasi oralABSTRACTPatients undergoing chemotherapy often experience problems in oral cavity. This could be happen because the chemotherapy agents cause direct destructive effect on surrounding tissues of the oral cavity, also indirectly by inducing myelosuppression and immunosuppression. Oral complications are often found in patients undergoing chemotherapy is an oral mucositis, candidiasis, xerostomia, taste dysfunction and hemorrhage. The purpose of this research is to describe the oral complications that occur in patients who are undergoing chemotherapy at BLU RSUP Prof Dr. Dr. R. D. Kandou Manado as well as the incidence of oral complications by age, gender, type of chemotherapy, duration of chemotherapy and other types of cancer experienced by these patients. The type of this research is descriptive with cross sectional study. Sampling was done by using purposive sampling with 64 samples were obtained by Cochran formula. The result showed that oral mucositis and xerostomia are the most oral complications experienced by patients after undergoing chemotherapy with an incidence of more than 60%. While other oral complications such as candidiasis, taste dysfunction and hemorrhage had an incidence of more than 25%. From the research, it is recommended to clinicians should pay more attention to a variety of oral complications arising in patients undergoing chemotherapy. Good cooperation between the patient, dentist and oncologist is very important to minimize the incidence of oral complications caused by chemotherapy treatment. Keywords: Patients undergoing chemotherapy, oral complications


2020 ◽  
Vol 30 (5) ◽  
pp. 346-357 ◽  
Author(s):  
A Izquierdo-Domínguez ◽  
MJ Rojas-Lechuga ◽  
C Chiesa-Estomba ◽  
C Calvo-Henríquez ◽  
E Ninchritz-Becerra ◽  
...  

Author(s):  
Daniel Hornuss ◽  
Berit Lange ◽  
Nils Schröter ◽  
Siegbert Rieg ◽  
Winfried V. Kern ◽  
...  

AbstractObjectivesCoronaviruses (CoVs) have a neuroinvasive propensity, and the frequently reported symptoms of smelling and taste dysfunction in many COVID-19 patients may be related to the respective capability of SARS-CoV2, the cause of the current pandemic. In this study we objectified and quantified the magnitude and underreporting of the smelling dysfunction caused by COVID-19 using a standardized test.MethodsWe conducted a prospective cross-sectional study comparing the proportion of anosmia using Sniffin-sticks in those reporting a loss of smell, in those who did not as well as in uninfected controls. The outcome of anosmic versus not anosmic patients were recorded during hospital stay and at day 15 on a six-category ordinal scale. The study was approved by the institutional review board, all participants consented to the study.Results40% of 45 consecutive hospitalized COVID-19 patients and 0% of 45 uninfected controls consenting were diagnosed with anosmia. 44% of anosmic and 50% of hyposmic patients did not report having smelling problems. Anosmia or hyposmia was not predictive of a severe COVID-19 manifestation.ConclusionsThe majority of COVID-19 patients have an objective anosmia and hyposmia, which often occurs unnoticed. These symptoms may be related to the neuroinvasive propensity of SARS-COV-2 and the unusual presentation of COVID-19 disease manifestations.


Author(s):  
Thua Nguyen Tran

Objective: Evaluation the relation between age at the time of diabetes diagnosis and glutamic acid decarboxylase (GAD) antibody in non- overweight, obese diabetic individuals. Method: A cross-sectional study on 284 non overweight- obesity diabetic patients at Hue Central hospital from August 2017 to August 2019. All patients were measured autoantibodies glutamic acid decarboxylase (anti-GAD). GAD antibody- positive was determined when autoantibodies to GAD concentration was higher than 5 IU/mL. Clinical data (age, sex, weight, hight) were obtained. Age at the time of diabetes diagnosis was interviewed. Data were analysed by SPSS version 16.0 and Medcalc software. Results: The risk of glutamic acid decarboxylase (GAD) antibody- positive in non- overweight, obese diabetic individuals increased 2.7 time when aged at the time of diabetes diagnosis 50 and older. The cut-off of age at the time of diabetes diagnosis for detecting risk of glutamic acid decarboxylase (GAD) antibody- positive in non- overweight, obese diabetic individuals was 57. Conclusion: This study showed non- overweight, obese diabetic individuals should be screened for glutamic acid decarboxylase (GAD) antibody at aged 50 and older


Author(s):  
A Jain ◽  
L Kumar ◽  
J Kaur ◽  
T Baisla ◽  
P Goyal ◽  
...  

Abstract Objectives To evaluate the occurrence, clinical course and outcomes of olfactory and gustatory dysfunction in patients with laboratory confirmed coronavirus disease 2019 infection. Methods This is a prospective cross-sectional study of patients diagnosed with coronavirus disease 2019 infection by reverse transcription polymerase chain reaction over two months. The epidemiological and clinical outcomes studied were: age, sex, general symptoms, and olfactory and taste dysfunction. Results A total of 410 coronavirus disease 2019 infected patients were included in the study, with 262 males (63.9 per cent) and 148 females (36.1 per cent). Ninety-nine patients (24.1 per cent) reported chemosensory dysfunction, of which 85 patients (20.7 per cent) reported both olfactory and taste dysfunction. Olfactory and taste dysfunction were proportionally more common in females. The mean duration of olfactory and taste dysfunction was 4.9 days, with a range of 2–15 days. Conclusion Olfactory and taste dysfunction are prevalent symptoms in coronavirus disease 2019 patients. In this study, they were more common in females than males. The occurrence of such dysfunctions is lower in the Indian population than in the European population.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Mehryar Mehrkash ◽  
Seyed-javad Golestaneh ◽  
Yahya Madihi ◽  
Fatemeh Paknazar ◽  
Mahdi Hadian ◽  
...  

Objective. Evaluation of the pruritus features in children with end-stage renal disease (ESRD) who underwent dialysis at an academic tertiary pediatric dialysis center. Methods. This cross-sectional study was conducted at an academic tertiary pediatric dialysis center, Isfahan, Iran. The reviewed medical records of the children included their characteristics, dialysis properties, and laboratory parameters. The 4-item itch questionnaire was utilized to assess distribution, severity, frequency, and associated sleeping disorders. Results. Thirty ESRD patients with pruritus, including 23 males (76.7%) with a mean age of 11.7 ± 3.64 years, were recruited. The most common cause of CKD was nephronophthisis (23.3%). The median total score of pruritus was 5 (range: 3-15). The distribution score of pruritus was directly correlated with the age (Spearman’s rho = 0 .42, P = 0.02 ) and serum level of parathyroid hormone (PTH) (Spearman’s rho = 0.42 , P = 0.04 ). In the reduced multiple logistic regression model, the increasing level of serum calcium was associated with increased odds of having total   pruritus   score ≥ 5 (OR (odds ratio): 4.5; 95% CI 1.12 to 18.05). In addition, an increase in age for one year was found to be associated with 50% higher odds of having total   pruritus   score ≥ 5 (OR: 1.5; 95% CI 1.03 to 2.18). Conclusion. Increased level of serum Ca and higher age were associated with increased odds of having more severe pruritus score in children.


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