Development of simvastatin electrospun fibers: a novel approach for sustained drug delivery

:Increasing research interest has been focused on controlled as well as sustained drug delivery using natural and biocompatible constituents in recent years. Many of them herbal constituents are avoided due to pharmacokinetic and pharmacodynamic issues of herbal constituents. There are many new technological ways and comparisons have been studied to upgrade the herbal discoveries in pharmaceutical market. This review will focus on the nanogel for herbal medicines with high delivery rate, patient compliance and efficiency. A nanoparticles contained hydrogel with cross linked polymer networks called as ‘Nanogel’. Nanogel preferred for herbal medicines due to stability and for the ease. Nanogels in terms of herbal drugs are promising and novel approach which also can be called as future generation drug delivery systems owing to high drug encapsulation capacity, uniformity, minimum toxicity, greater stability.

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Knitted Silk Fibroin-Reinforced Bead-on-String Electrospun Fibers for Sustained Drug Delivery Against Colon Cancer

Macromolecular Materials and Engineering ◽

10.1002/mame.201700666 ◽

2018 ◽

Vol 303 (5) ◽

pp. 1700666 ◽

Cited By ~ 2

Author(s):

Panpan Ma ◽

Shuangquan Gou ◽

Min Wang ◽

Jiucun Chen ◽

Wei Hu ◽

...

Keyword(s):

Drug Delivery ◽

Colon Cancer ◽

Silk Fibroin ◽

Electrospun Fibers ◽

Sustained Drug Delivery

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Combination of Low and High Molecular Weight Chitosans for the Preparation of Nanoparticles: A Novel Approach Towards Sustained Drug Delivery

Journal of Nanopharmaceutics and Drug Delivery ◽

10.1166/jnd.2013.1031 ◽

2013 ◽

Vol 1 (4) ◽

pp. 376-387 ◽

Cited By ~ 2

Author(s):

Yogesh Choudhari ◽

Sushant Kulthe ◽

Nazma Inamdar ◽

Seema Shirolikar ◽

Lalit Borde ◽

...

Keyword(s):

Drug Delivery ◽

Molecular Weight ◽

High Molecular Weight ◽

Sustained Drug Delivery ◽

Novel Approach

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HPMC Polymeric System: Structural Contribution in Controlling Drug Release in Sustained Drug Delivery System

International Journal of Pharmaceutical Research ◽

10.31838/ijpr/2021.13.01.325 ◽

2020 ◽

Vol 13 (01) ◽

Keyword(s):

Drug Delivery ◽

Drug Release ◽

Drug Delivery System ◽

Delivery System ◽

Polymeric System ◽

Sustained Drug Delivery ◽

Structural Contribution

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Plantago Ovata and Locust Bean Gum as a Natural Polymer in Hydrodynamically Balanced Systems: A Review

Journal of Biomedical and Allied Research ◽

10.37191/mapsci-2582-4937-2(1)-015 ◽

2020 ◽

Author(s):

Ghildiyal s

Keyword(s):

Drug Delivery ◽

Locust Bean Gum ◽

Main Role ◽

Natural Polymer ◽

Release Formulation ◽

Sustained Drug Delivery ◽

Modern Drug ◽

Buccal Drug Delivery ◽

Locust Bean ◽

Ceratonia Siliqua L

Hydrodynamically Balanced systems have wide development as they have achieved the parameters of modern drug delivery system, it is a type of system which owes very tremendous and curative benefits for the delivery of oral controlled release dosage forms and have wide properties in many aspects such as its main role is to maintain the effective concentration in the system for longer period of time. To reduce the gastric mucosal irritation due to the presence of synthetic polymers, being a natural polymer incorporation of Plantago ovate (Psyllium Husk) could ease out the mucosal irritation in the gastric region. Due to its properties such as a rate-controlling polymer possessing a very good quality of swelling and good gelling nature, and also incorporated as a matrix-forming agent basically in the modified release formulation. Locust bean gum can be used as sustained-release carriers and release modifiers for the delivery of drugs. It is a neutral plant galactomannan extracted from the seeds (kernels) of the carob tree Ceratonia siliqua L fabaceae. Nowadays it is focussing polymer and a lot of researchers are focussing on exploring the potential in topical drug delivery, colonic drug delivery, oral sustained drug delivery, ocular drug delivery, buccal drug delivery.

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Carbon Nanotubes, Quantum Dots and Dendrimers as Potential Nanodevices for Nanotechnology Drug Delivery Systems

International Journal of Pharmaceutical Sciences and Nanotechnology ◽

10.37285/ijpsn.2013.6.3.2 ◽

2013 ◽

Vol 6 (3) ◽

pp. 2113-2124

Author(s):

Prashant Malik ◽

Neha Gulati ◽

Raj Kaur Malik ◽

Upendra Nagaich

Keyword(s):

Carbon Nanotubes ◽

Drug Delivery ◽

Quantum Dots ◽

Self Assembly ◽

Drug Delivery Systems ◽

Delivery Systems ◽

Atomic Scale ◽

Sustained Drug Delivery ◽

Pharmaceutical Nanotechnology ◽

Conventional Device

Nanotechnology deal with the particle size in nanometers. Nanotechnology is ranging from extensions of conventional device physics to completely new approaches based upon molecular self assembly, from developing new materials with dimensions on the nanoscale to direct control of matter on the atomic scale. In nanotechnology mainly three types of nanodevices are described: carbon nanotubes, quantum dots and dendrimers. It is a recent technique used as small size particles to treat many diseases like cancer, gene therapy and used as diagnostics. Nanotechnology used to formulate targeted, controlled and sustained drug delivery systems. Pharmaceutical nanotechnology embraces applications of nanoscience to pharmacy as nanomaterials and as devices like drug delivery, diagnostic, imaging and biosensor materials. Pharmaceutical nanotechnology has provided more fine tuned diagnosis and focused treatment of disease at a molecular level.

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