Acute Effects of Training Loads on Muscle Damage Markers and Performance in Semi-elite and Elite Athletes: A Systematic Review and Meta-analysis

2021 ◽  
Author(s):  
Ryan Simmons ◽  
Kenji Doma ◽  
Wade Sinclair ◽  
Jonathan Connor ◽  
Anthony Leicht
Keyword(s):  
Systematic Review ◽  
Muscle Damage ◽  
Elite Athletes ◽  
Meta Analysis ◽  
Acute Effects ◽  
And Performance ◽  
Muscle Damage Markers

scholarly journals The effect of branched-chain amino acid on muscle damage markers and performance following strenuous exercise: a systematic review and meta-analysis

2021 ◽  
pp. 1-11
Author(s):  
Kenji Doma ◽  
Utkarsh Singh ◽  
Daniel Boullosa ◽  
Jonathan Douglas Connor
Keyword(s):  
Systematic Review ◽  
Muscle Damage ◽  
Muscle Soreness ◽  
Meta Analysis ◽  
Muscle Performance ◽  
Strenuous Exercise ◽  
Post Exercise ◽  
Branched Chain ◽  
And Performance ◽  
Muscle Damage Markers

This systematic review and meta-analysis determined whether the ergogenic effects of branched-chain amino acids (BCAA) ameliorated markers of muscle damage and performance following strenuous exercise. In total, 25 studies were included, consisting of 479 participants (age 24.3 ± 8.3 years, height 1.73 ± 0.06 m, body mass 70.8 ± 9.5 kg, females 26.3%). These studies were rated as fair to excellent following the PEDro scale. The outcome measures were compared between the BCAA and placebo conditions at 24 and 48 hours following muscle-damaging exercises, using standardised mean differences and associated p-values via forest plots. Our meta-analysis demonstrated significantly lower levels of indirect muscle damage markers (creatine kinase, lactate dehydrogenase and myoglobin) at 48 hours post-exercise (standardised mean difference [SMD] = −0.41; p < 0.05) for the BCAA than placebo conditions, whilst muscle soreness was significant at 24 hours post-exercise (SMD = −0.28 ≤ d ≤ −0.61; p < 0.05) and 48 hours post-exercise (SMD = −0.41 ≤ d≤ −0.92; p < 0.01). However, no significant differences were identified between the BCAA and placebo conditions for muscle performance at 24 or 48 hours post-exercise (SMD = 0.08 ≤ d ≤ 0.21; p > 0.05). Overall, BCAA reduced the level of muscle damage biomarkers and muscle soreness following muscle-damaging exercises. However, the potential benefits of BCAA for muscle performance recovery is questionable and warrants further investigation to determine the practicality of BCAA for ameliorating muscle damage symptoms in diverse populations. PROSPERO registration number: CRD42020191248. Novelty: BCAA reduces the level of creatine kinase and muscle soreness following strenuous exercise with a dose–response relationship. BCAA does not accelerate recovery for muscle performance.

scholarly journals Does exercising at a certain time-of-day affect athletes skeletal muscle damage markers? A systematic review and meta-analysis

2019 ◽  
Vol 5 (1) ◽  
pp. 1670529 ◽  
Author(s):  
Efrem Kentiba ◽  
Argachew Adane ◽  
Mezgebe Mena ◽  
Zerihun Zekarias ◽  
Zenebech Abera ◽  
...  
Keyword(s):  
Systematic Review ◽  
Skeletal Muscle ◽  
Muscle Damage ◽  
Meta Analysis ◽  
Time Of Day ◽  
Skeletal Muscle Damage ◽  
Muscle Damage Markers

scholarly journals Impact of eating disorders on paid or unpaid work participation and performance: a systematic review and meta-analysis protocol

2022 ◽  
Vol 10 (1) ◽  
Author(s):  
Fatima Safi ◽  
Anna M. Aniserowicz ◽  
Heather Colquhoun ◽  
Jill Stier ◽  
Behdin Nowrouzi-Kia
Keyword(s):  
Systematic Review ◽  
Eating Disorders ◽  
Meta Analysis ◽  
Experimental Studies ◽  
Work Participation ◽  
Unpaid Work ◽  
Cochrane Library ◽  
And Performance ◽  
The Impact

Abstract Background Eating disorders (ED) can reduce quality of life by limiting participation and performance in social and occupational roles, including paid or unpaid work. The association between ED pathologies and work participation and performance must be well understood to strengthen vocational rehabilitation programmes and prevent occupational disruptions in the ED population. The aims of this study are: (1) to examine the degree of association between ED pathologies and work participation and performance in 15-year-olds and older; (2) to highlight the specific ED symptoms that are most correlated with changes in work performance and participation; (3) to compile the most common metrics and assessments used to measure work participation and performance with ED. Methods Medline, Embase, CINAHL, Web of Science, PsycINFO, and Cochrane Library will be searched for observational and experimental studies that meet the following criteria: (1) a clinical sample of typical or atypical ED; (2) paid or unpaid employment or training; (3) an association between ED pathologies and work participation or performance. Unpublished data will also be examined. Title and abstract, and full-text screening will be conducted in duplicate. Risk of bias and quality of evidence assessments will be completed. A random-effect meta-analysis will be performed. Discussion This synthesis can clarify knowledge and gaps around the impact of ED on work functioning, thereby allowing better evaluation, improvements and development of current workplace assessments, interventions, and policies. Trial registration The registration number for this systematic review on PROSPERO is CRD42021255055.

Post Endoscopy Barrett’s Neoplasia (PEBN) After A Negative Index Endoscopy: A Systematic Review & Proposal For Definitions and Performance Measures in Endoscopy

Endoscopy ◽  
2022 ◽  
Author(s):  
Madhav Desai ◽  
David A Lieberman ◽  
Sachin Srinivasan ◽  
Venkat Nutalapati ◽  
Abhishek Challa ◽  
...  
Keyword(s):  
Systematic Review ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Meta Analysis ◽  
Incidence Rates ◽  
High Rate ◽  
Negative Index ◽  
Inclusion Criteria ◽  
Surveillance Interval ◽  
And Performance

Background and aims: A high rate of neoplasia (high grade dysplasia; HGD and esophageal adenocarcinoma; EAC) has been reported in Barrett’s Esophagus at index endoscopy but precise rates of post endoscopy Barrett’s neoplasia (PEBN) are unknown. Methods: Systematic review and meta-analysis was performed examining electronic databases (inception to October 2021) for studies reporting PEBN. Consistent with definitions of Post Colonoscopy Colorectal Cancer as proposed by the World Endoscopy Organization, we defined neoplasia(HGD/EAC) detected at index endoscopy and/or within 6 months of a negative index endoscopy as “prevalent” neoplasia; those detected after 6 months of a negative index endoscopy and prior to next surveillance interval(i.e. 3 years) as PEBN or “interval” neoplasia, and those detected after 36 months of a negative index endoscopy as “incident” neoplasia. Pooled incidence rates and proportion relative to total neoplasia were analyzed. Results: 11 studies (n=59,795, age:62.3±3.3 years, 61%males) met inclusion criteria. The pooled incidence rates were: prevalent neoplasia 4.5% (95%confidence interval: 2.2-8.9) at baseline and additional 0.3%(0.1-0.7) within first 6 months, PEBN 0.52%(0.48-0.58) and incident neoplasia: 1.41%(0.93-2.14). At 3 years from index endoscopy, PEBN accounted for 3% while prevalent neoplasia accounted for 97% of total Barrett’s neoplasia. Conclusion: Neoplasia detected at or within 6 months of index endoscopy account for most of the Barrett’s neoplasia(>90%). Post-Endoscopy Barrett’s Neoplasia account for ~3% of cases and can be used for validation in future. This highlights the importance of a high-quality index endoscopy in Barrett’s Esophagus and the need to establish quality benchmarks to measure endoscopists’ performance.

scholarly journals Determinants of anxiety in elite athletes: a systematic review and meta-analysis

2019 ◽  
Vol 53 (11) ◽  
pp. 722-730 ◽  
Author(s):  
Simon M Rice ◽  
Kate Gwyther ◽  
Olga Santesteban-Echarri ◽  
David Baron ◽  
Paul Gorczynski ◽  
...  
Keyword(s):  
Systematic Review ◽  
Life Events ◽  
Female Athletes ◽  
Elite Athletes ◽  
Meta Analysis ◽  
Adverse Life Events ◽  
Eligibility Criteria ◽  
Quantitative Studies ◽  
Online Databases ◽  
Symptom Level

ObjectiveTo identify and quantify determinants of anxiety symptoms and disorders experienced by elite athletes.DesignSystematic review and meta-analysis.Data sourcesFive online databases (PubMed, SportDiscus, PsycINFO, Scopus and Cochrane) were searched up to November 2018 to identify eligible citations.Eligibility criteria for selecting studiesArticles were included if they were published in English, were quantitative studies and measured a symptom-level anxiety outcome in competing or retired athletes at the professional (including professional youth), Olympic or collegiate/university levels.Results and summaryWe screened 1163 articles; 61 studies were included in the systematic review and 27 of them were suitable for meta-analysis. Overall risk of bias for included studies was low. Athletes and non-athletes had no differences in anxiety profiles (d=−0.11, p=0.28). Pooled effect sizes, demonstrating moderate effects, were identified for (1) career dissatisfaction (d=0.45; higher anxiety in dissatisfied athletes), (2) gender (d=0.38; higher anxiety in female athletes), (3) age (d=−0.34; higher anxiety for younger athletes) and (4) musculoskeletal injury (d=0.31; higher anxiety for injured athletes). A small pooled effect was found for recent adverse life events (d=0.26)—higher anxiety in athletes who had experienced one or more recent adverse life events.ConclusionDeterminants of anxiety in elite populations broadly reflect those experienced by the general population. Clinicians should be aware of these general and athlete-specific determinants of anxiety among elite athletes.

scholarly journals Acute effects of caffeine intake on athletic performance: A systematic review and meta-analysis

2017 ◽  
Vol 44 (3) ◽  
pp. 283-283 ◽  
Author(s):  
Beatriz Gonçalves Ribeiro ◽  
Anderson Pontes Morales ◽  
Felipe Sampaio-Jorge ◽  
Felipe de Souza Tinoco ◽  
Alessandra Alegre de Matos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Athletic Performance ◽  
Meta Analysis ◽  
Caffeine Intake ◽  
Acute Effects
Sign in / Sign up

Export Citation Format

Share Document