Carotid intima media thickness and other cardiovascular risk factors in children with congenital adrenal hyperplasia

2014 ◽  
Vol 37 (10) ◽  
pp. 1001-1008 ◽  
Author(s):  
N. H. Amr ◽  
A. Y. Ahmed ◽  
Y. A. Ibrahim
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Congenital Adrenal Hyperplasia ◽  
Cardiovascular Risk Factors ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Adrenal Hyperplasia ◽  
Media Thickness

scholarly journals Cardiovascular risk factors and increased carotid intima-media thickness in young patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency

2015 ◽  
Vol 59 (6) ◽  
pp. 541-547 ◽  
Author(s):  
Tânia Maria Barreto Rodrigues ◽  
Cristina Botelho Barra ◽  
Jovita Lane Soares Santos ◽  
Eugênio Marcos Andrade Goulart ◽  
Adaliene Versiani Matos Ferreira ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Congenital Adrenal Hyperplasia ◽  
Cardiovascular Risk Factors ◽  
Young Patients ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Adrenal Hyperplasia ◽  
Hydroxylase Deficiency ◽  
21 Hydroxylase Deficiency

scholarly journals Meta-analysis of epigenome-wide association studies of carotid intima-media thickness

2021 ◽  
Author(s):  
Eliana Portilla-Fernández ◽  
Shih-Jen Hwang ◽  
Rory Wilson ◽  
Jane Maddock ◽  
W. David Hill ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Dna Methylation ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Association Studies ◽  
Subclinical Atherosclerosis ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness

AbstractCommon carotid intima-media thickness (cIMT) is an index of subclinical atherosclerosis that is associated with ischemic stroke and coronary artery disease (CAD). We undertook a cross-sectional epigenome-wide association study (EWAS) of measures of cIMT in 6400 individuals. Mendelian randomization analysis was applied to investigate the potential causal role of DNA methylation in the link between atherosclerotic cardiovascular risk factors and cIMT or clinical cardiovascular disease. The CpG site cg05575921 was associated with cIMT (beta = −0.0264, p value = 3.5 × 10–8) in the discovery panel and was replicated in replication panel (beta = −0.07, p value = 0.005). This CpG is located at chr5:81649347 in the intron 3 of the aryl hydrocarbon receptor repressor gene (AHRR). Our results indicate that DNA methylation at cg05575921 might be in the pathway between smoking, cIMT and stroke. Moreover, in a region-based analysis, 34 differentially methylated regions (DMRs) were identified of which a DMR upstream of ALOX12 showed the strongest association with cIMT (p value = 1.4 × 10–13). In conclusion, our study suggests that DNA methylation may play a role in the link between cardiovascular risk factors, cIMT and clinical cardiovascular disease.

scholarly journals Association Between Carotid Intima Media Thickness, Age, and Cardiovascular Risk Factors in Children and Adolescents

2018 ◽  
Vol 16 (3) ◽  
pp. 122-126 ◽  
Author(s):  
Vasu D. Gooty ◽  
Alan R. Sinaiko ◽  
Justin R. Ryder ◽  
Donald R. Dengel ◽  
David R. Jacobs ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Children And Adolescents ◽  
Cardiovascular Risk Factors ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness

Arterial stiffness changes in patients with cardiovascular risk factors but normal carotid intima–media thickness

2013 ◽  
Vol 14 (9) ◽  
pp. 622-628 ◽  
Author(s):  
Moemen Mohammed ◽  
Concetta Zito ◽  
Maurizio Cusmà-Piccione ◽  
Gianluca Di Bella ◽  
Francesco Antonini-Canterin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Arterial Stiffness ◽  
Cardiovascular Risk Factors ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness

scholarly journals Childbearing, Child-Rearing, Cardiovascular Risk Factors, and Progression of Carotid Intima-Media Thickness

Stroke ◽  
2010 ◽  
Vol 41 (7) ◽  
pp. 1332-1337 ◽  
Author(s):  
Michael R. Skilton ◽  
Fabrice Bonnet ◽  
Lisa M. Begg ◽  
Markus Juonala ◽  
Mika Kähönen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Child Rearing ◽  
Media Thickness
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