scholarly journals Intolerance of uncertainty predicts fear of healthcare settings but not desire for testing during the novel coronavirus pandemic

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Milen L. Radell ◽  
Brian M. McGuire
Keyword(s):  
Medical Information ◽  
Health Anxiety ◽  
Intolerance Of Uncertainty ◽  
Healthcare Setting ◽  
The United States ◽  
General Tendency ◽  
The Novel ◽  
Healthcare Settings ◽  
Novel Coronavirus ◽  
The Cost

AbstractThe novel coronavirus (COVID-19) pandemic has caused unprecedented uncertainty, and differences in how people cope with this uncertainty will influence the cost of viral pandemics to both individuals and society. The personality trait of intolerance of uncertainty (IU), defined as a dispositional fear of the unknown, has been linked to higher health anxiety and fear of the virus. Although IU may increase the desire for medical information and treatment, during pandemics, this might be weighed against the risk of becoming infected while in a healthcare setting. We examined whether people with higher IU report greater fear of healthcare settings, and show more desire to be tested for the virus. Residents of the United States (n = 149) were surveyed in early May 2020, while most states had active stay-at-home orders. Higher prospective but not inhibitory IU predicted more fear of healthcare settings. The largest effect size, however, was for fear of leaving the home, indicating a general tendency toward fear and avoidance. Fear of leaving the home, perceiving the virus as dangerous, access to testing, and having symptoms were significant predictors of desire for testing.

scholarly journals Belonging in the Coronaverse: Will There Be Time?

2021 ◽  
Vol 1 (1) ◽  
pp. 100-115
Author(s):  
Kate Fischer ◽  
Malika Rakhmonova ◽  
Mike Tran
Keyword(s):  
College Experience ◽  
The United States ◽  
Limited Time ◽  
The Novel ◽  
Residential University ◽  
To Come ◽  
Novel Coronavirus ◽  
University Experience ◽  
The U.S ◽  
Older Siblings

Abstract Since the spring of 2020 SARS-CoV-2, the novel coronavirus, has upended lives and caused a rethinking of nearly all social behaviors in the United States. This paper examines the ways in which the pandemic, shutdown, and gradual move towards “normal” have laid bare and obfuscated societal pressures regarding running out of time as it pertains to the residential university experience. Promised by movies, television, and older siblings and friends as a limited-time offer, the “typical” college experience is baked into the U.S. imaginary, reinforcing a host of notions of who “belongs” on campus along lines of race, class, and age. Fed a vision of what their whole lives “should be”, students who enter a residential four-year college are already imbued with a nostalgia for what is yet to come, hailed, in Althusser’s (2006[1977]) sense, as university subjects even before their first class. The upheaval of that subjecthood during the pandemic has raised important questions about the purpose of the college experience as well as how to belong to a place that is no longer there.

scholarly journals Covid-19 and food security: Jeopardy management and posterity deliberations

2021 ◽  
Vol 10 (2) ◽  
pp. 01-05
Author(s):  
Augustine Owusu-Addo ◽  
Atianashie Miracle A ◽  
Chukwuma Chinaza Adaobi ◽  
Larissa Agbemelo-Tsomafo
Keyword(s):  
Food Processing ◽  
Respiratory Illness ◽  
The United States ◽  
The Novel ◽  
Food Handling ◽  
Global Pandemic ◽  
Food Borne ◽  
Novel Coronavirus ◽  
Food Borne Infections ◽  
Safety Guidelines

COVID-19, also known as the ‘novel coronavirus disease 2019’, is a respiratory illness and the causative pathogen is officially named as ‘SARS-CoV-2’. Infections with SARS-CoV-2 have now been amplified to a global pandemic – as of April 3, 2020, nearly 1,018,000 cases have been confirmed in more than 195 countries, including more than 300,000 cases within the United States. Public safety guidelines are followed worldwide to stop the spread of COVID-19 and stay healthy. Despite COVID-19 is a respiratory illness with mode of invasion through the respiratory tract, not the gastrointestinal tract, an average food consumer is anxious and concerned about the food safety. Could an individual catch the deadly contagious COVID-19 from groceries brought home from the supermarket – or from the next restaurant takeout order? This brief review elucidates the epidemiology and pathobiological mechanism(s) of SARS-CoV-2 and its implications in food-borne infections, transmission via food surfaces, food processing and food handling.

Curating the Evidence About COVID-19 for Frontline Public Health and Clinical Care: The Novel Coronavirus Research Compendium

2021 ◽  
pp. 003335492110587
Author(s):  
Andrew D. Redd ◽  
Lauren S. Peetluk ◽  
Brooke A. Jarrett ◽  
Colleen Hanrahan ◽  
Sheree Schwartz ◽  
...  
Keyword(s):  
Public Health ◽  
Clinical Care ◽  
The United States ◽  
The Novel ◽  
Health Crisis ◽  
The Public ◽  
Successful Model ◽  
Medical Response ◽  
Public Consumption ◽  
Novel Coronavirus

The public health crisis created by the COVID-19 pandemic has spurred a deluge of scientific research aimed at informing the public health and medical response to the pandemic. However, early in the pandemic, those working in frontline public health and clinical care had insufficient time to parse the rapidly evolving evidence and use it for decision-making. Academics in public health and medicine were well-placed to translate the evidence for use by frontline clinicians and public health practitioners. The Novel Coronavirus Research Compendium (NCRC), a group of >60 faculty and trainees across the United States, formed in March 2020 with the goal to quickly triage and review the large volume of preprints and peer-reviewed publications on SARS-CoV-2 and COVID-19 and summarize the most important, novel evidence to inform pandemic response. From April 6 through December 31, 2020, NCRC teams screened 54 192 peer-reviewed articles and preprints, of which 527 were selected for review and uploaded to the NCRC website for public consumption. Most articles were peer-reviewed publications (n = 395, 75.0%), published in 102 journals; 25.1% (n = 132) of articles reviewed were preprints. The NCRC is a successful model of how academics translate scientific knowledge for practitioners and help build capacity for this work among students. This approach could be used for health problems beyond COVID-19, but the effort is resource intensive and may not be sustainable in the long term.

scholarly journals Novel Coronavirus, Old Partisanship: COVID-19 Attitudes and Behaviours in the United States and Canada

2020 ◽  
Vol 53 (2) ◽  
pp. 357-364 ◽  
Author(s):  
Mark Pickup ◽  
Dominik Stecula ◽  
Clifton van der Linden
Keyword(s):  
United States ◽  
Early Response ◽  
The United States ◽  
Political Elites ◽  
The Novel ◽  
The Us ◽  
Media Reports ◽  
American Case ◽  
Conservative Media ◽  
Novel Coronavirus

The novel coronavirus reached the United States and Canada almost at the same time. The first reported American case was January 20, 2020, and in Canada it was January 15, 2020 (Canada, 2020; Holshue et al., 2020). Yet, the response to this crisis has been different in the two countries. In the US, President Donald Trump, prominent Republicans, and conservative media initially dismissed the dangers of COVID-19 (Stecula, 2020). The pandemic became politicized from the early days, and even though Trump and Republicans have walked back many of their initial claims, there continue to be media reports of partisan differences in public opinion shaped by that early response. At the same time, the response in Canada has been mostly characterized by across-the-board partisan consensus among political elites (Merkley et al., 2020).

scholarly journals Citation Network Analysis of the Novel Coronavirus Disease 2019 (COVID-19)

2020 ◽  
Vol 17 (20) ◽  
pp. 7690 ◽  
Author(s):  
Clara Martinez-Perez ◽  
Cristina Alvarez-Peregrina ◽  
Cesar Villa-Collar ◽  
Miguel Ángel Sánchez-Tena
Keyword(s):  
Web Of Science ◽  
Citation Network ◽  
The United States ◽  
Disease Spread ◽  
The Novel ◽  
Research Areas ◽  
Citation Network Analysis ◽  
Number Of Publications ◽  
Novel Coronavirus ◽  
The Relationship

Background: The first outbreaks of the new coronavirus disease, named COVID-19, occurred at the end of December 2019. This disease spread quickly around the world, with the United States, Brazil and Mexico being the countries the most severely affected. This study aims to analyze the relationship between different publications and their authors through citation networks, as well as to identify the research areas and determine which publication has been the most cited. Methods: The search for publications was carried out through the Web of Science database using terms such as “COVID-19” and “SARS-CoV-2” for the period between January and July 2020. The Citation Network Explorer software was used for publication analysis. Results: A total of 14,335 publications were found with 42,374 citations generated in the network, with June being the month with the largest number of publications. The most cited publication was “Clinical Characteristics of Coronavirus Disease 2019 in China” by Guan et al., published in April 2020. Nine groups comprising different research areas in this field, including clinical course, psychology, treatment and epidemiology, were found using the clustering functionality. Conclusions: The citation network offers an objective and comprehensive analysis of the main papers on COVID-19 and SARS-CoV-2.

Who Counts? Old Age in COVID Times

2020 ◽  
Vol 92 (4) ◽  
pp. 745-757
Author(s):  
Jane F. Thrailkill
Keyword(s):  
United States ◽  
Old Age ◽  
Risk Group ◽  
The United States ◽  
The Novel ◽  
Novel Coronavirus ◽  
Congregate Care ◽  
Structural Inequalities

Abstract People over sixty-five have been singled out as a uniquely vulnerable risk group for the novel coronavirus. Yet the discourse of risk obscures (and exacerbates) socially created dangers of congregate care in the United States: poorly paid workers holding down multiple jobs and the endemic “plagues” of loneliness, boredom, and hopelessness. Humorous memes about who counts as old point out structural inequalities, while millions of able-bodied “shut-ins” (due to lockdowns and job losses) may experience forced empathy: fuel for new imaginings about how to care for—and value—elders moving forward.

scholarly journals The IMPDH inhibitor merimepodib provided in combination with the adenosine analogue remdesivir reduces SARS-CoV-2 replication to undetectable levels in vitro

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 361
Author(s):  
Natalya Bukreyeva ◽  
Rachel A. Sattler ◽  
Emily K. Mantlo ◽  
Timothy Wanninger ◽  
John T. Manning ◽  
...  
Keyword(s):  
Disease Burden ◽  
Vero Cells ◽  
The United States ◽  
The Novel ◽  
Infectious Titer ◽  
Adenosine Analogue ◽  
Pre Treatment ◽  
Novel Coronavirus ◽  
Dose Dependent

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the novel coronavirus responsible for the ongoing COVID-19 pandemic, which has resulted in over 2.5 million confirmed cases and 170,000 deaths worldwide as of late April 2020. The pandemic currently presents major public health and economic burdens worldwide. No vaccines or therapeutics have been approved for use to treat COVID-19 cases in the United States despite the growing disease burden, thus creating an urgent need for effective treatments. The adenosine analogue remdesivir (REM) has recently been investigated as a potential treatment option, and has shown some activity in limiting SARS-CoV-2 replication. We previously reported that the IMPDH inhibitor merimepodib (MMPD) provides a dose-dependent suppression of SARS-CoV-2 replication in vitro. Here, we report that a 4-hour pre-treatment of Vero cells with 2.5µM MMPD reduces the infectious titer of SARS-CoV-2 more effectively than REM at the same concentration. Additionally, pre-treatment of Vero cells with both REM and MMPD in combination reduces the infectious titer of SARS-CoV-2 to values below the detectable limit of our TCID50 assay. This result was achieved with concentrations as small as 1.25 µM MMPD and 2.5 µM REM. At concentrations of each agent as low as 0.31 µM, significant reduction of viral production occurred. This study provides evidence that REM and MMPD administered in combination might be an effective treatment for COVID-19 cases.

scholarly journals COVID-19 in Africa: The cost of perceived low incidence rates

2021 ◽  
Vol 2 (1) ◽  
pp. 050-054
Author(s):  
David Olufemi Adesanya ◽  
Precious Chidozie Azubuike
Keyword(s):  
Viral Disease ◽  
Information Management System ◽  
Incidence Rates ◽  
The Novel ◽  
African Countries ◽  
Care Workers ◽  
Low Incidence ◽  
Novel Coronavirus ◽  
The Cost ◽  
The Impact

COVID-19 is a viral disease caused by the novel coronavirus and has hit many countries of the world heavily. The impact of COVID-19 in Africa, is contrary to the experts and professional predictions. Most African have very poor healthcare systems, water supply, sanitary environment and other factors that are requisite to combating the spread of the virus. Reports on COVID-19 incidence from Africa may not be a true reflection of the actual situation. The poor health information management system predominant in most African countries and the inability to carry out effective testing for cases could be responsible for this reported low incidence rates. The implications of perceived low incidence constitute a burden to governments of nations, health care workers, educational and other institutions, communities, women and girls; as well as members of the population. As the virus spreads across Africa, there is a need to improve active case finding and report same to enable effective planning and resource mobilization towards containing the spread of the virus.

scholarly journals Protective Immunity against COVID-19

2021 ◽  
Author(s):  
Anjali Priyadarshini ◽  
Archana Gupta ◽  
Manoj Kumar Yadav ◽  
Arpana Vibhuti ◽  
Ramendra Pati Pandey ◽  
...  
Keyword(s):  
United States ◽  
Immune Responses ◽  
Drug Administration ◽  
United States Of America ◽  
Protective Immunity ◽  
The United States ◽  
The Novel ◽  
Infectious Agents ◽  
Novel Coronavirus ◽  
Target Effects

Tuberculosis and Covid-19 infection measure two quite different diseases- TB is caused by a sort of bacterium whereas Covid-19 is caused by a virus. However, the BCG immunizing agent would possibly facilitate individuals build immune responses to things aside from TB, inflicting "off-target effects," In different words, in run format, individuals started learning positive in obtaining the immunizing agent that had nothing to try and do with TB, several studies showed however the BCG immunizing agent affects individuals with kind one although the precise mechanism for these off-target effects of the BCG immunizing agent is not clear, it's believed that the immunizing agent will cause a nonspecific boost of the reaction. There is presently no immunizing agent or treatments approved by the United States of America Food and Drug Administration for the novel coronavirus. BCG is usually innocuous with the most facet impact the event of inflammation at the positioning of injection. Supported by these observations BCG so emerges as a possible candidate for the development of innate and adjustive reactions which can be non-specifically taking care of mycobacterium and different infectious agents against that vaccine remains not on the market.

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