Effect of ethanol on prostaglandin E2 receptor in rat submandibular salivary glands

1992 ◽  
Vol 37 (11) ◽  
pp. 869-873 ◽  
Author(s):  
C.Y. Wu-Wang ◽  
S.-L. Wang ◽  
C. Lim ◽  
A. Slomiany ◽  
B.L. Slomiany
Keyword(s):  
Prostaglandin E2 ◽  
Salivary Glands ◽  
Submandibular Salivary Glands ◽  
Prostaglandin E2 Receptor

Prostaglandin E2 receptor of rat submandibular salivary glands

1991 ◽  
Vol 36 (9) ◽  
pp. 637-640 ◽  
Author(s):  
C.Y. Wu-Wang ◽  
S.-L. Wang ◽  
P. Yao ◽  
A. Slomiany ◽  
B.L. Slomiany
Keyword(s):  
Prostaglandin E2 ◽  
Salivary Glands ◽  
Submandibular Salivary Glands ◽  
Prostaglandin E2 Receptor

scholarly journals Qualitative ultrastructural analysis of the submandibular salivary glands after administration of khat: in vivo study

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Gamilah Al-Qadhi ◽  
Rabab Mubarak
Keyword(s):  
Salivary Glands ◽  
Arabian Peninsula ◽  
Submandibular Salivary Gland ◽  
Catha Edulis ◽  
Ductal Cells ◽  
Cytoplasmic Vacuoles ◽  
Transmission Electron ◽  
Salivary Gland Cells ◽  
Submandibular Salivary Glands

Abstract Objective Khat (Catha edulis Forssk) plant has been widely chewed for its psychostimulatory effects in the African and Arabian Peninsula, particularly in Yemen. Considering the khat leaves are gradually chewed without swallowing, while its active constituents are extracted into saliva, studying the effect of khat on salivary glands is necessary. This work is an extension of the previously published work that studied the effect of khat extract on the rats' submandibular salivary glands in terms of histological and immunohistochemical evaluations. The current research note aimed to better understand this effect on the ultrastructure of submandibular salivary gland cells by using transmission electron microscope. Results Oral administration of khat extract produced degenerative changes in the secretory and ductal cells of rats' submandibular salivary glands. These changes involved irregular boundaries of variable sized-nuclei, dilated RER, cytoplasmic vacuoles as well as swollen and degenerated mitochondria.

Localization of Chromogranins, Non-neuron-specific Enolase, and Different Forms of Somatostatins in the Submandibular Salivary Glands of Mice

1990 ◽  
Vol 69 (8) ◽  
pp. 1494-1499 ◽  
Author(s):  
A. Letić-Gavrilović ◽  
K. Abe
Keyword(s):  
Growth Factor ◽  
Salivary Glands ◽  
Chromogranin A ◽  
Neuron Specific Enolase ◽  
Biologically Active ◽  
Detection Methods ◽  
Duct System ◽  
Male Mice ◽  
Chromogranin B ◽  
Submandibular Salivary Glands

The localizations of chromogranins A, B, and C, neuron-specific enolase (NSE, γγ-type) and non-NSE (αα-type), and different forms of somatostatins were immunocytochemically identified. The localizations were compared with those of epidermal growth factor (EGF) and nerve growth factor (NGF) in the submandibular salivary glands (SMG) of male mice at five to six weeks of age, with use of a variety of antibodies and the peroxidase-antiperoxidase (PAP) and avidin-biotin complex (ABC) detection methods. In the SMG of male mice, the major chromogranin present was chromogranin A, whereas chromogranins B and C were not detected at these ages by either method. Chromogranin Alike immunoreactivity was located in the granular convoluted tubule (GCT) cells of the SMG, whereas non-NSE immunoreactivity was observed throughout the duct system and in some acinar-associated cells. NSE was not detected in any part of the SMG. The distribution of chromogranin A and somatostatins in the GCT cells was similar to that of EGF and NGF. Our results strongly suggest that chromogranin A and somatostatins, but not chromogranin B or C, may be useful as a means of differentiation of the cells in the duct system of the SMG responsible for the production of biologically-active factors.

scholarly journals Syntenin-1 promotes colorectal cancer stem cell expansion and chemoresistance by regulating prostaglandin E2 receptor

2020 ◽  
Vol 123 (6) ◽  
pp. 955-964
Author(s):  
Kazuya Iwamoto ◽  
Hidekazu Takahashi ◽  
Daisuke Okuzaki ◽  
Hideo Osawa ◽  
Takayuki Ogino ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Prostaglandin E2 ◽  
Cell Expansion ◽  
Stem Cell Expansion ◽  
Prostaglandin E2 Receptor
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