The body weight loss of young rats caused by hepatic branch vagotomy is influenced by environmental temperature

1988 ◽  
Vol 43 (5) ◽  
pp. 673-675 ◽  
Author(s):  
Takeo Sakaguchi ◽  
Makoto Tamaki
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Environmental Temperature ◽  
Body Weight Loss ◽  
The Body ◽  
Young Rats ◽  
Hepatic Branch

Effect of environmental temperature on hamster body fat composition

1964 ◽  
Vol 19 (5) ◽  
pp. 863-867 ◽  
Author(s):  
Arthur M. Kodama ◽  
Nello Pace
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Body Weight ◽  
Body Fat ◽  
Environmental Temperature ◽  
Caloric Intake ◽  
Body Weight Loss ◽  
Fat Content ◽  
The Body ◽  
Body Fat Content

Body fat content and the melting point and fatty acid composition of body fat of hamsters exposed to 35, 27, 20, 15, 10, and 6 C for 2 weeks were determined. The relationship between exposure temperature and body fat content and composition resembled that between environmental temperature and metabolic rate. Below the critical temperature, there was a progressive decrease in total body fat content and melting point accompanied by a decrease in the mole fraction of palmitic acid and an increase in the mole fraction of oleic acid. The softening of body fat in cold-exposed animals appears to be the result of an increased mobilization of depot fat in response to a higher metabolic rate in the cold, a mobilization which is at least partially selective with respect to individual fatty acids or triglycerides. Examination of changes in whole body composition revealed that 72% of the loss in body weight of hamsters exposed to 6 C was due to a decrease in body fat content. In contrast, the decrease in body fat content accounted for only 28% of the body weight loss of pair-fed hamsters kept at 27 C on reduced caloric intake to match the body weight loss experienced by cold-exposed animals. It appears, therefore, that cold exposure induces a more effective fat depot mobilization than does reduced caloric intake. heat exposure; cold exposure; body composition Submitted on February 3, 1964

scholarly journals Liraglutide, a GLP-1 Receptor Agonist, Which Decreases Hypothalamic 5-HT2A Receptor Expression, Reduces Appetite and Body Weight Independently of Serotonin Synthesis in Mice

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Katsunori Nonogaki ◽  
Takao Kaji
Keyword(s):  
Gene Expression ◽  
Weight Loss ◽  
Body Weight ◽  
Receptor Agonist ◽  
Tryptophan Hydroxylase ◽  
Intraperitoneal Administration ◽  
Body Weight Loss ◽  
Receptor Activation ◽  
The Body ◽  
Receptor Expression

A recent report suggested that brain-derived serotonin (5-HT) is critical for maintaining weight loss induced by glucagon-like peptide-1 (GLP-1) receptor activation in rats and that 5-HT2A receptors mediate the feeding suppression and weight loss induced by GLP-1 receptor activation. Here, we show that changes in daily food intake and body weight induced by intraperitoneal administration of liraglutide, a GLP-1 receptor agonist, over 4 days did not differ between mice treated with the tryptophan hydroxylase (Tph) inhibitor p-chlorophenylalanine (PCPA) for 3 days and mice without PCPA treatment. Treatment with PCPA did not affect hypothalamic 5-HT2A receptor expression. Despite the anorexic effect of liraglutide disappearing after the first day of treatment, the body weight loss induced by liraglutide persisted for 4 days in mice treated with or without PCPA. Intraperitoneal administration of liraglutide significantly decreased the gene expression of hypothalamic 5-HT2A receptors 1 h after injection. Moreover, the acute anorexic effects of liraglutide were blunted in mice treated with the high-affinity 5-HT2A agonist (4-bromo-3,6-dimethoxybenzocyclobuten-1-yl) methylamine hydrobromide 14 h or 24 h before liraglutide injection. These findings suggest that liraglutide reduces appetite and body weight independently of 5-HT synthesis in mice, whereas GLP-1 receptor activation downregulates the gene expression of hypothalamic 5-HT2A receptors.

scholarly journals Some results of winter keeping of paddlefish young-of-the-year (Polyodon spathula (Walbaum, 1792)) in ponds of the Forest-Steppe and Polesye of Ukraine

2020 ◽  
pp. 59-67
Author(s):  
B. Hankevych ◽  
◽  
O. Tretiak ◽  
O. Kolos ◽  
◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Environmental Conditions ◽  
Body Weight Loss ◽  
Fish Farming ◽  
The Body ◽  
Average Weight ◽  
Forest Steppe ◽  
Study Results ◽  
Young Of The Year

Purpose. Assessing the results of winter keeping of paddlefish young-of-the-year in ponds of the Forest-steppe and Polesye of Ukraine. Methodology. The study was carried out using 0.05-1.0 ha ponds intended for winter keeping of carps. The stocking density of paddlefish young-of-the-year with an average weight of 94.2-147.2 g in wintering ponds was 4.10-16.63 thousand fish/ha. The study of the physicochemical parameters of the aquatic environment was carried out according to the methods generally accepted in hydrochemistry and fish farming. The main piscicultural-biological parameters during the wintering period of fish were assessed using methods commonly used in ichthyology and fish farming according to the level of survival and body weight loss of paddlefish. Findings. The environmental conditions in the ponds during most of the wintering period of fish met the biological requirements of the studied object of cultivation. The water temperature varied within 0.9-6.50C. The dissolved oxygen content in water did not fall below 3.6-3.8 mgO2/dm3 and was mainly at the level of 3.9-7.9 3.9-7.2 mgO2/dm3. Other hydrochemical parameters were within acceptable values ​​for wintering fish in pond conditions. As a result, the survival rate of paddlefish young-of-the-year during the wintering period was 81.5-89.7%. The body weight loss of fish during the winter keeping was on average in the range of 6.41-8.17%. A conclusion was made on the need to conduct additional studies of physiological and biochemical parameters of paddlefish during the wintering period. Originality. New data were obtained on the peculiarities of wintering of paddlefish seeds in ponds of the Forest-steppe and Polesye of Ukraine. Practical value. The study results are part of the database for the development of improved technologies for sturgeon breeding in Ukraine. Key words: paddlefish, fish seeds, pond aquaculture, fish wintering, environmental conditions, piscicultural parameters.

scholarly journals Therapy of obesity by sibutramin: polymorphisms of TPH2 and GNB3 genes and decrease of body weight

2018 ◽  
Vol 15 (2) ◽  
pp. 40-45
Author(s):  
Marina O. Galieva ◽  
Ekaterina A. Troshina ◽  
Nataliya V. Mazurina ◽  
Anna P. Volynkina ◽  
Andrey V. Artiushin ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Weight Loss ◽  
Body Weight ◽  
Genetic Factors ◽  
Research Study ◽  
Body Weight Loss ◽  
The Body ◽  
Tph2 Gene

Aims. To study of the polymorphisms of the TPN2 and GNB3 genes in obese patients and their effect on weight loss in patients on sibutramine therapy. Materials and methods. The research study included 118 patients with exogenous-constitutional obesity who received Reduxin (sibutramine + CMC) at the dose of 10 mg. Term follow-up was 3 months. A genetic study was performed to assess ТРН2 and GNB3 gene polymorphisms. The response to the therapy was evaluated after 3 months by the dynamics of body weight. Results. In the study the G703T polymorphism of the GNB3 gene showed that during 3 months of observation, carriers of the TT genotype had a greater decrease in body weight in comparison with carriers of the allele C -8 kg (-12; -5) vs. -5 kg (-8; -3), p = 0.018. In carriers of different variants of the genotype of the TPH2 gene (polymorphism C825T), there was no difference in body weight dynamics with sibutramine therapy. There was no correlation between the foresaid polymorphisms of the TPH2 and GNB3 genes with the indices of blood pressure and heart rate. Conclusions. 1. The result of sibutramin therapy may depend on genetic factors: in carriers of the TT-genotype C825T of the GNB3 gene the body weight loss was higher than among the carriers of the C allele. 2. Changes in blood pressure and heart rate did not show any statistically significant relationship with polymorphisms of the TPH2 and GNB3 genes.

The Body Weight Loss And Core Temperature Regulation During And After Ultramarathon Running

2009 ◽  
Vol 41 ◽  
pp. 491
Author(s):  
Fong Chou Kuo ◽  
Kai Yang Tseng ◽  
Jin Jong Chen ◽  
Shun Ping Lin ◽  
Wei Fong Kao ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Core Temperature ◽  
Temperature Regulation ◽  
Body Weight Loss ◽  
The Body

Some factors associated with the behaviour and survival of newly shorn sheep

1969 ◽  
Vol 20 (3) ◽  
pp. 513 ◽  
Author(s):  
KJ Hutchinson ◽  
BH McRae
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Body Condition ◽  
Management Practices ◽  
Body Weight Loss ◽  
The Body ◽  
High Rate ◽  
Zona Fasciculata ◽  
Mortality Level ◽  
Factors Associated

Sheep deaths in the 12-day period following shearing were related to a high rate of body weight loss during the 4 weeks before shearing. The body weight or body condition of sheep at shearing was unimportant. Mortality level was not influenced by the amount of herbage available after shearing although the grazing activities of the survivors increased. Mortality was associated with a massive infiltration of lipid into the zona fasciculata of the adrenal cortex.The shorn sheep spent more time standing and less time grazing during the night. These results are discussed in relation to possible management practices to reduce sheep losses.

Diet and body weight loss in the rat during calorie restriction

1968 ◽  
Vol 46 (1) ◽  
pp. 101-107
Author(s):  
Peter B. Karch ◽  
John R. Beaton
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Body Fat ◽  
Resting Metabolic Rate ◽  
Urine Volume ◽  
Body Weight Loss ◽  
The Body ◽  
Male Rats ◽  
Calorie Intake ◽  
Isocaloric Diets

With adult male rats, experiments were carried out to ascertain the different effects, if any, of isocaloric diets high in carbohydrate, fat, or protein fed in restricted amounts of 9 g per rat per day on body weight loss and composition. It was observed that the nature of the diet did not alter rate, amount, or composition of body weight loss when fed in restricted amount for a period of 12 days. Further, the nature of the diet did not alter significantly the following parameters during restriction: water intake, urine volume, resting metabolic rate, spontaneous activity, urine and feces calorie values. In an experiment with hypothalamic-obese rats, the body weight loss and composition were not significantly different among the dietary-restricted groups. An important observation in this experiment was that as body fat decreased markedly owing to restricted feeding, body water increased markedly and counterbalanced approximately 60% of the potential weight loss due to the decrease in body fat. Our reported observations do not support the hypothesis that the composition of the diet may determine the rate and amount of body weight loss as a consequence of restricted food intake. They do support the hypothesis that the calorie intake, not the nature of the source of calories, determines the rate and amount of weight loss, at least for relatively short periods of food restriction.

scholarly journals Changes in skeletal muscle cellularity in starved and refed young rats

1980 ◽  
Vol 44 (2) ◽  
pp. 123-127 ◽  
Author(s):  
P. V. J. Hegarty ◽  
K. O. Kim
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Fibre Diameter ◽  
Body Weight Loss ◽  
The Body ◽  
Muscle Fibres ◽  
Stock Diet ◽  
Epididymal Fat ◽  
Kidney Liver ◽  
Fat Pads

1. All food was withdrawn from male weanling rats until a 40% loss of body-weight was attained. Another group of animals was treated similarly and then refed a stock diet until the original body-weight was attained.2. The body-weight loss caused a significant reduction in the weight of the heart, kidney, liver and epididymal fat pads. Refeeding produced a return to the control weight of the heart and kidney, an increase in the weight of the liver and a deficit in the weight of the epididymal fat pads.3. Body-weight loss caused a decrease in the weight of the three different muscles studied, and in the number and diameter of the fibres in each muscle. Refeeding restored the weight and cellularity of two of the three muscles to that of the control animals. The soleus muscle was heavier in the refed animals when compared to controls due to an increased fibre diameter.4. It is concluded that the decrease in the number and diameter of muscle fibres during starvation in the rat can be restored on refeeding a stock diet.

Randomized controlled trial comparing Billroth-I and Roux-en-Y reconstruction in distal gastrectomy for gastric cancer.

2011 ◽  
Vol 29 (4_suppl) ◽  
pp. 65-65 ◽  
Author(s):  
J. Fujita ◽  
H. Imamura ◽  
S. Takiguchi ◽  
K. Fujitani ◽  
I. Miyashiro ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Weight Loss ◽  
Body Weight ◽  
Postoperative Morbidity ◽  
Distal Gastrectomy ◽  
Controlled Trial ◽  
Body Weight Loss ◽  
The Body ◽  
Billroth I ◽  
Randomized Controlled

65 Background: In distal subtotal gastrectomy for gastric cancer, Billroth-I (B-I) reconstruction has been performed predominantly in Japan, while increasing number of surgeons chose Roux-en-Y (R-Y) reconstruction recently. To evaluate the safety and superiority of R-Y we conducted a multi-institutional prospective randomized controlled trial. Methods: Gastric cancer patients who underwent distal gastrectomy were randomized to B-I or R-Y intraoperatively. The primary endpoint was the ratio of body weight loss 1 year after surgery, the secondary endpoints were the incidence of delayed gastric emptying (DGE) and postoperative morbidity. Results: Between Aug 2005 and Dec 2008, a total of 332 patients were enrolled and 163 patients were assigned to B-I and 169 patients to R- Y. The patient's characteristics were well balanced between the two groups. The operation time was significantly longer in R-Y than B-I (median 180 min in B-I vs 214 min in R-Y, p < 0.0001). The postoperative morbidity was 14 patients (8.6%) in B-I and 23 (13.6%) in R-Y (p = 0.14), the incidence of DGE was 7 (4.3%) in B-I vs 16 (9.5%) in R-Y (p = 0.06), and the hospital stay after surgery was 14.1days in B-I vs 16.4 days in R-Y (p = 0.02). There was no hospital death in the two groups. The body weight loss at 1 year after surgery compared to preoperation was -5.4kg (-9.1%) in B-I vs -6.2kg (-9.8%) in R-Y (p = 0.11). Conclusions: The advantage of R- Y reconstruction compared to B-I was not proved in terms of postoperative morbidity either the body weight loss 1 year after surgery. No significant financial relationships to disclose.

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