l-Tryptophan production from anthranilic acid by amino acid auxotrophic mutants of Candida utilis

1994 ◽  
Vol 29 (7) ◽  
pp. 521-527 ◽  
Author(s):  
A. Möller
Chemoecology ◽  
2003 ◽  
Vol 13 (2) ◽  
pp. 75-80 ◽  
Author(s):  
Hiroe Yasui ◽  
Sadao Wakamura ◽  
Norio Arakaki ◽  
Mitsunobu Kishita ◽  
Yasutsune Sadoyama

1990 ◽  
Vol 45 (2) ◽  
pp. 258-266 ◽  
Author(s):  
Martin Feigel ◽  
Gerhard Lugert ◽  
Javier Manero ◽  
Matthias Bremer

Starting from tert-Butyloxycarbonyl(BOC)-Anthranilic-Acid(Abz) (1), BOC-Abz-Proline-Methyl-Ester (2) is synthesized. The crystal structure of both compounds are discussed. The conformational features of the crystal structures of 2 are compared with the conformation in solution. The whole conformational area (Φ and Ψ) of the amino acid part of 2 was investigated with the semi-empirical quantummechanical method AM 1, in order to check the general availability of the influence of ester functions to depsipeptide conformations. Cyclo-anthranoyl-prolinyl (3), which had already been described in the literature, forms crystals with a high density. Two independent molecules are found in the crystal structure; these molecules have very similar conformations.


1978 ◽  
Vol 42 (6) ◽  
pp. 1207-1211 ◽  
Author(s):  
Masaru IIZUKA ◽  
Hiroshi CHIURA ◽  
Takehiko YAMAMOTO

1979 ◽  
Vol 25 (4) ◽  
pp. 486-490 ◽  
Author(s):  
J. M. Delgado ◽  
L. S. Herrera ◽  
C. Pérez ◽  
R. López

The determination of the best conditions for the application of the snail enzyme digestion method in the enrichment of auxotrophic mutants in Candida utilis was carried out following Box and Wilson's mathematical method. The selection procedure proposed was tested in the enrichment of auxotrophic mutants from a mutagenized culture of a wild-type strain. Mutant frequency was increased 46-fold by treatment with snail enzyme. The method also proved useful in the selection of additional auxotrophic mutations from single auxotrophs.


1966 ◽  
Vol 12 (4) ◽  
pp. 775-785 ◽  
Author(s):  
P. S. S. Dawson ◽  
B. M. Craig

Total lipids were extracted from cells of Candida utilis grown in batch, chemostat, and phased culture. Thin-layer chromatography of the extracts showed qualitative changes in the different lipid classes with growth. Gas–liquid chromatography was used to follow quantitative changes in the fatty acid constituents. Changes were found to be analogous to those previously reported for the amino acid pool, i.e., characteristic of the medium, of growth rate, and of the environment. The significance of the changes, and of the methods used to detect them, are discussed in relation to the growth and metabolism of the cell and of the culture.


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