Anti-inflammatory activity in the venom of Apis mellifera (the common European honey bee)

Toxicon ◽  
1983 ◽  
Vol 21 ◽  
pp. 29-32 ◽  
Author(s):  
Barbara EC Banks ◽  
Christopher E Dempsey ◽  
E. Barboni
Antibiotics ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1514
Author(s):  
Iouraouine El Mehdi ◽  
Soraia I. Falcão ◽  
Mustapha Harandou ◽  
Saïd Boujraf ◽  
Ricardo C. Calhelha ◽  
...  

The venom from Apis mellifera intermissa, the main honey bee prevailing in Morocco, has been scarcely studied, despite its known potential for pharmacological applications. In the present work, we investigated the composition, the anti-inflammatory activity, and the venom’s cytotoxic properties from fifteen honey bee venom (HBV) samples collected in three regions: northeast, central, and southern Morocco. The chemical assessment of honey bee venom was performed using LC-DAD/ESI/MSn, NIR spectroscopy and AAS spectroscopy. The antiproliferative effect was evaluated using human tumor cell lines, including breast adenocarcinoma, non-small cell lung carcinoma, cervical carcinoma, hepatocellular carcinoma, and malignant melanoma. Likewise, we assessed the anti-inflammatory activity using the murine macrophage cell line. The study provides information on the honey bee venom subspecies’ main components, such as melittin, apamin, and phospholipase A2, with compositional variation depending on the region of collection. Contents of toxic elements such as cadmium, chromium, and plumb were detected at a concentration below 5 ppm, which can be regarded as safe for pharmaceutical use. The data presented contribute to the first study in HBV from Apis mellifera intermissa and highlight the remarkable antiproliferative and anti-inflammatory effects of HBV, suggesting it to be a candidate natural medicine to explore.


2018 ◽  
Vol 16 (S1) ◽  
pp. S143-S148
Author(s):  
M. Touaibia

This study was designed to evaluate the chemical composition and anti-inflammatory activity of the common myrtle (Myrtus communisL.) essential oil. The composition ofMyrtus communisL. essential oil, extracted by steam distillation, was characterized by a high fraction (80.9%) of oxygenated monoterpenes. The major components were myrtenyl acetate (38.7%), eucalyptol (12.7%), α-pinene (13.7%), and linalool (7.00%). The chemical profile of this essential oil allows us to classify it as myrtényle acétate/α- pinène chemotype, but with atypical proportions, related to the harvesting area. In the carrageenan-induced paw edema, five different groups were established and the essential oil was administered orally in three different doses. The common myrtle essential oil (100 mg/kg) was able to reduce the paw edema, with a comparable effect to that observed with diclofenac (positive control). This is the first report to demonstrate a significant anti-inflammatory activity of Algerian common myrtle essential oil.


2019 ◽  
Vol 18 (3-4) ◽  
pp. 156-161
Author(s):  
M. Touaibia

This study was designed to evaluate the chemical composition and anti-inflammatory activity of the common myrtle essential oil (Myrtus communis L.). The essential oil composition of Myrtus communis L. extracted by steam distillation was characterized by a high oxygenated monoterpene fraction (80.9%). The major components were myrtenyl acetate (38.7%), eucalyptol (12.7%), α-pinene (13.7%), and linalool (7.00%). The chemical profile of this essential oil allows us to classify it as myrtényle acétate/α-pinène chemotype, but with atypical proportions, related to the harvesting area. In the carrageenan-induced paw edema, five different groups were established and the essential oil was administered orally in three different doses. The common myrtle essential oil (100 mg/kg) was able to reduce the paw edema, with a comparable effect to that observed with Diclofenac (positive control). This is the first report to demonstrate a significant anti-inflammatory activity of Algerian common myrtle essential oil.


Author(s):  
Sumesh Shah ◽  
Amit Gupta ◽  
Shweta P Karne ◽  
Sanjay Kamble ◽  
Bharat Shinde

2013 ◽  
pp. 59-63
Author(s):  
Erika Zakar ◽  
Edit Zajácz ◽  
Tímea Rácz ◽  
János Oláh ◽  
András Jávor ◽  
...  

The honey bees are essential for the pollination of agricultural plants. The Pannonian honey bee, Apis mellifera pannonica, is native to Hungary, only these subspecies are being bread in our country. The parameters have been separated the pannon and italian honey bee subspecies, the colour of tergit, the cubital index and proboscis length. The morphometric analisys is of special importance because this, on the one hand, shows correlation with honey bee production and on the other hand, the pure morphometric charactersitics is the basis of any potential honey bee export. Mitochondrial DNA and microsatellites are the common methods to define genetic diversity and the separation of subspecies.


1952 ◽  
Vol 29 (3) ◽  
pp. 372-386
Author(s):  
G. D. GLYNNE JONES

1. This paper is concerned, first, with the development of a technique for maintaining a population of honey-bees (Apis mellifera) under conditions where it does not have access to naturally secreted nectar, but is allowed free flying conditions, and secondly with the application of this technique to the study of the chemotropic responses of bees to repellent chemicals. 2. Two types of stimuli are considered: (a) The effect of the addition of the repellent to an attractant (sucrose solution). (b) The effect of the repellent in the vapour phase in the vicinity of the attractant. In (a) techniques are described for measuring the response with the standard attractant alternating in time and space. 3. Data collected on the rejection thresholds of acetic acid and phenol showed that whilst little variation in response occurred at the higher concentrations of the repellent, the offering of the standard attractant alternating in time as opposed to space greatly modified the response. Tests were carried out to determine the reproducibility of the results. 4. It would appear that for a repellent chemical to be capable of effectively reducing the number of visits to a source of food, it must be capable of irritating the common chemical senses of the bee.


2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
C. S. Henne ◽  
E. Rodriguez ◽  
J. J. Adamczyk

Using a combination of flower traps and visual observations, we surveyed three watermelon (Citrullus lanatus(Thunb.) Matsum. & Nakai) fields in the Lower Rio Grande Valley to determine what bees inhabit this crop in this region. No managed honey bee (Apis melliferaL.) hives were in any of the fields; however, two contained managed hives of the common eastern bumble bee,Bombus impatiens(Cresson). A total of 15 species were collected or observed from all three fields combined. Of these species, only four were found to be very abundant:Agapostemon angelicusCockerell/texanusCresson,A. mellifera,Lasioglossum coactum(Cresson), andMelissodes thelypodiiCockerell.Apis melliferacomprised 46% of all bees collected from all three fields combined and was highly abundant in two of the three fields. In the third field, however,A. melliferaandAgapostemon angelicus/texanuswere equally abundant. Surprisingly,B. impatienscomprised only 1% of the total bees surveyed in all three fields combined, despite two of the fields having several managed hives each. AsB. impatiensis not native to this region, it was not surprising that none were collected or observed in the field with no managed hives.


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