Monounsaturated and polyunsaturated fatty acids: structure, food sources, biological functions, and their preventive role against noncommunicable diseases

2022 ◽  
pp. 185-210
Author(s):  
Miguel Ángel Rincón-Cervera ◽  
Roberto Bravo-Sagua ◽  
Rosana Aparecida Manólio Soares Freitas ◽  
Sandra López-Arana ◽  
Adriano Costa de Camargo
Lipids ◽  
2006 ◽  
Vol 41 (5) ◽  
pp. 415-422 ◽  
Author(s):  
Isabelle A. Sioen ◽  
Hse Pynaert ◽  
Christophe matthys ◽  
Guy De Backer ◽  
John Van Camp ◽  
...  

Lipids ◽  
2013 ◽  
Vol 48 (7) ◽  
pp. 729-738 ◽  
Author(s):  
Isabelle Sioen ◽  
Krishna Vyncke ◽  
Mieke De Maeyer ◽  
Monique Gerichhausen ◽  
Stefaan De Henauw

2018 ◽  
Vol 59 (12) ◽  
pp. 1937-1948 ◽  
Author(s):  
GianLuca Colussi ◽  
Cristiana Catena ◽  
Valentina Fagotto ◽  
Daniele Darsiè ◽  
Gabriele Brosolo ◽  
...  

2021 ◽  
Author(s):  
Paulo Cartaxana ◽  
Felisa Rey ◽  
Charlotte Lekieffre ◽  
Diana Lopes ◽  
Cedric Hubas ◽  
...  

Some sea slugs are able to steal functional chloroplasts (kleptoplasts) from their algal food sources, but the role and relevance of photosynthesis to the animal host remain controversial. While some researchers claim that kleptoplasts are slowly digestible snacks, others advocate that they enhance the overall fitness of sea slugs much more profoundly. Our analysis show light-dependent incorporation of 13C and 15N in the albumen gland and gonadal follicles of the sea slug Elysia timida, representing translocation of photosynthates to kleptoplast-free reproductive organs. Long-chain polyunsaturated fatty acids with reported roles in reproduction were produced in the sea slug cells using labelled precursors translocated from the kleptoplasts. Finally, we report reduced fecundity of E. timida by suppressing kleptoplast photosynthesis. The present study provides the first thorough experimental evidence that photosynthesis enhances the reproductive fitness of kleptoplast-bearing sea slugs, confirming the biological relevance of this remarkable association between a metazoan and an algal-derived organelle.


Author(s):  
Marinka Steur ◽  
Laura Johnson ◽  
Stephen J. Sharp ◽  
Fumiaki Imamura ◽  
Ivonne Sluijs ◽  
...  

Background There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids [SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically, the relevance of food sources of SFAs to CHD associations is uncertain. Methods and Results We conducted a case‐cohort study involving 10 529 incident CHD cases and a random subcohort of 16 730 adults selected from a cohort of 385 747 participants in 9 countries of the EPIC (European Prospective Investigation into Cancer and Nutrition) study. We estimated multivariable adjusted country‐specific hazard ratios (HRs) and 95% CIs per 5% of energy intake from dietary fatty acids, with and without isocaloric macronutrient substitutions, using Prentice‐weighted Cox regression models and pooled results using random‐effects meta‐analysis. We found no evidence for associations of the consumption of total or fatty acid classes with CHD, regardless of macronutrient substitutions. In analyses considering food sources, CHD incidence was lower per 1% higher energy intake of SFAs from yogurt (HR, 0.93 [95% CI, 0.88–0.99]), cheese (HR, 0.98 [95% CI, 0.96–1.00]), and fish (HR, 0.87 [95% CI, 0.75–1.00]), but higher for SFAs from red meat (HR, 1.07 [95% CI, 1.02–1.12]) and butter (HR, 1.02 [95% CI, 1.00–1.04]). Conclusions This observational study found no strong associations of total fatty acids, SFAs, monounsaturated fatty acids, and polyunsaturated fatty acids, with incident CHD. By contrast, we found associations of SFAs with CHD in opposite directions dependent on the food source. These findings should be further confirmed, but support public health recommendations to consider food sources alongside the macronutrients they contain, and suggest the importance of the overall food matrix.


Author(s):  
Antonio Molino ◽  
Angela Iovine ◽  
Patrizia Casella ◽  
Sanjeet Mehariya ◽  
Simeone Chianese ◽  
...  

The exploration of new food sources and natural products is the result of the increase in world population as well as the need for a healthier diet; in this context, microalgae are undoubtedly an interesting solution. With the intent to enhance their value in new commercial applications, this paper aims to characterize microalgae that have already been recognized as safe or authorized as additives for humans and animals (Chlorella vulgaris, Arthrospira platensis, Haematococcus pluvialis, Dunaliella salina) as well as those that have not yet been marketed (Scenedesmus almeriensis and Nannocholoropsis sp.). In this scope, the content of proteins, carbohydrates, lipids, total dietary fiber, humidity, ash, and carotenoids has been measured via standard methods. In addition, individual carotenoids (beta-carotene, astaxanthin, and lutein) as well as individual saturated, monounsaturated, and polyunsaturated fatty acids have been identified and quantified chromatographically. The results confirm the prerogative of some species to produce certain products such as carotenoids, polyunsaturated fatty acids, and proteins, but also show how their cellular content is rich and diverse. H. pluvialis green and red phases, and Nannochloropsis sp., in addition to producing astaxanthin and omega-3, contain about 25–33% w/w proteins on a dry basis. D. salina is rich in beta-carotene (3.45% w/w on a dry basis), S. Almeriensis is a source of lutein (0.30% w/w on a dry basis), and the C. vulgaris species is a protein-based microalgae (45% w/w on a dry basis). All, however, can also produce important fatty acids such as palmitic acid, γ-linolenic acid, and oleic acid. Considering their varied composition, these microalgae can find applications in multiple sectors. This is true for microalgae already on the market as well as for promising new sources of bioproducts such as S. almeriensis and Nannochloropsis sp.


2021 ◽  
pp. 1-28
Author(s):  
G Buckland ◽  
S de Silva Johnson ◽  
L Johnson ◽  
C Taylor ◽  
LR Jones ◽  
...  

Abstract An adequate intake of polyunsaturated fatty acids (PUFAs) plays a vital role in human health. Therefore, it is important to assess PUFA intakes in different populations and validate them with biomarkers, but only a few small studies are in paediatric populations. We calculated the dietary intake of PUFAs and their main food sources in children and assessed associations between reported PUFA intakes and plasma proportions. Dietary intakes of 7-year-old children (n=8,242) enrolled in the Avon Longitudinal Study of Parents and Children were calculated from parental-completed food frequency questionnaire. Plasma PUFAs were measured in 5,571 children 8 months later and 4,380 children had complete dietary and plasma data. The association between dietary and plasma PUFAs proportions were estimated using Spearman’s correlation coefficients, quintile cross-classification and Cohen’s kappa coefficients. Mean total PUFA intake was 13.2g/day (sd4.2), contributing 6.5% of total energy intake; n-6 PUFA contributed 5.2% and n-3 PUFA 0.7%. The n-6:n-3 ratio was 7.9:1. Mean intakes of eicosapentaenoic acid and docosahexaenoic acid (DHA) were 35.7mg/day and 49.7mg/day, respectively. Most n-3 and n-6 PUFA intakes were weakly correlated with their respective plasma lipids (0.07≤ r ≤0.16, p<0.001). The correlation between dietary and plasma DHA was stronger though (r=0.34, p<0.001), supported by a modest level of agreement between quintiles (k=0.32). The results indicate that the FFQ was able to reasonably rank the long-chain PUFA, DHA, in this paediatric population. Public health initiatives need to address the suboptimal ratio of n-6:n-3 PUFAs and very low n-3 long-chain PUFA intakes in school-aged children in the UK.


Lipids ◽  
2003 ◽  
Vol 38 (4) ◽  
pp. 391-398 ◽  
Author(s):  
Barbara J. Meyer ◽  
Neil J. Mann ◽  
Janine L. Lewis ◽  
Greg C. Milligan ◽  
Andrew J. Sinclair ◽  
...  

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
María Susana Feliu ◽  
◽  
Inés Fernández ◽  
Nora Slobodianik

Omega 3 fatty acids are polyunsaturated fatty acids, essential since the human body does not produce them and they are obtained mainly from the diet. They confer flexibility, fluidity and selective permeability to the membranes, which favors cardiovascular health, reduces the risk of deficiencies in vision and neural development in infants and children, and dementia in older adults; some of them are precursors in the synthesis of prostaglandins. Some effects have also been seen in the prevention and treatment of coronary heart disease, hypertension, diabetes, arthritis, inflammation, autoimmune disorders, and cancer. These effects can be explained through the specific actions of each of them. Dietary fat influences the modulation of immune functions and inflammatory processes; most of the impact is attributed to long-chain polyunsaturated fatty acids (LCPUFA). The EPA exerts: hypotriglyceridemic effect at LDL and VLDL level; hypocholesterolemic effect due to increase in bile efflux and reverse cholesterol transport; antithrombotic effect due to the formation of Series 3 eicosanoids. DHA: increases the fluidity of neuronal, glial, and cone and rod membranes; decreases neuronal apoptosis; facilitates the recycling of neurotransmitters; regulates the expression of enzymes involved in lipid metabolism as a ligand for PPARs; inhibits insulin resistance to muscle and fat tissues. The intake recommendations are: 6 polyunsaturated fatty acids: 2.5-9% of energy intake/daily, and ω3 polyunsaturated fatty acids: 0.6-2.0% of energy intake/daily. Key words: omega-3 fatty acids; food sources; immune system; pathologies.


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