Symptoms and Type of Symptom Onset in Acute Coronary Syndrome in Relation to ST Elevation, Sex, Age, and a History of Diabetes

2005 ◽  
Vol 14 (12) ◽  
pp. 4
Author(s):  
M. Thuresson ◽  
M. Berglin Jarlöv ◽  
B. Lindahl ◽  
L. Svensson ◽  
C. Zedigh ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Symptom Onset ◽  
Coronary Syndrome ◽  
History Of ◽  
St Elevation

Symptoms and type of symptom onset in acute coronary syndrome in relation to ST elevation, sex, age, and a history of diabetes

2005 ◽  
Vol 150 (2) ◽  
pp. 234-242 ◽  
Author(s):  
Marie Thuresson ◽  
Marianne Berglin Jarlöv ◽  
Bertil Lindahl ◽  
Leif Svensson ◽  
Crister Zedigh ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Symptom Onset ◽  
Coronary Syndrome ◽  
History Of ◽  
St Elevation

scholarly journals Epidemiology and risk factors of patients with types of acute coronary syndrome presenting to a tertiary care hospital in Sri Lanka

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Udaya Ralapanawa ◽  
Pallegoda Vithanage Ranjith Kumarasiri ◽  
Kushalee Poornima Jayawickreme ◽  
Prabashini Kumarihamy ◽  
Yapa Wijeratne ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Sri Lanka ◽  
Unstable Angina ◽  
Stable Angina ◽  
Strong Association ◽  
Coronary Syndrome ◽  
History Of ◽  
St Elevation

Abstract Background Acute Coronary Syndrome (ACS) is one of the leading causes of death worldwide and studies have shown higher mortality rates and premature death in South Asian countries. The occurrence and effect of risk factors differ by type ofACS.Epidemiological studies in the Sri Lankan population are limited. Methods This is a cross sectional descriptive study conducted at the Teaching Hospital Peradeniya, Sri Lanka among patients presenting with ACS. Data was collected by an interviewer administered structured questionnaire and epidemiological patterns and risk factors were analyzed. Results The sample of 300 patients had a mean age of 61.3+/− 12.6 and male sex showed higher association with all three type of ACS compared to female with a P value of 0.001. This study showed higher mean age of 62.2 ± 11.4 years amongst unstable angina (UA) patients and 61.9 ± 14.5 years amongst non ST elevation myocardial infarction (NSTEMI) patients compared to 59.2 ± 11.2 years for ST elevation myocardial infarction (STEMI) patients with no significant statistical difference (P = 0.246). Approximately 55.8% STEMI patients, 39.8% UA and 35.5% NSTEMI patients were smokers indicating a significant association between smoking and STEMI (P = 0.017). Nearly 54.5% STEMI, 35.4% UA and 32.7% NSTEMI patients consumed alcohol and there was a very strong association between alcohol consumption and STEMI (P = 0.006). Almost 51.8% NSTEMI patients, 47.8% UA patients and 29.9% STEMI patients had hypertension(HT) (P = 0.008) indicating significant association of HT with UA and NSTEMI. About 33.6% UA patients and 30.0% NSTEMI patients had DM whilst only 22.1% of STEMI patients had DM of no significance (p = 0.225). Around 15.0% patients with UA, 25.5% with NSTEMI and 11.7% with STEMI had dyslipidemia (P = 0.032). There was a very strong association between a past history of ACS or stable angina with NSTEMI and UA (P = 0.001). Conclusion Smoking and alcohol abuse are significantly associated with STEMI.Patients with NSTEMI or Unstable Angina had higher rates of hypertension and were more likely to have a history of ACS or stable angina than STEMI patients. Patients with NSTEMI were more likely than patients with STEMI or UA to have dyslipidemia.

scholarly journals TCTAP C-019 The Clinical History of a 88 Year-old Female with Acute Coronary Syndrome with ST Elevation and Frederick’s Syndrome

2017 ◽  
Vol 69 (16) ◽  
pp. S108-S109
Author(s):  
Alexey Biryukov ◽  
Ekaterina Leonidovna Zaslavskaya ◽  
Kirill Alexeevich Smirnov ◽  
Andrei Aleksandrovich Voronkov ◽  
Dmitriy Vladimirovich Ovcharenko
Keyword(s):  
Acute Coronary Syndrome ◽  
Clinical History ◽  
Coronary Syndrome ◽  
History Of ◽  
St Elevation

Breast cancer patients have lower in-hospital mortality after acute coronary syndrome, a 5 year nationwide analysis

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
C Huang Lucas ◽  
B Yue ◽  
X Wei ◽  
L Wu ◽  
R Abed ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Acute Coronary Syndrome ◽  
Hospital Mortality ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Female Population ◽  
Female Patients ◽  
Coronary Syndrome ◽  
History Of ◽  
St Elevation

Abstract Background Breast cancer and cardiovascular disease (CVD) share common risk factors, and breast cancer therapies are well known to cause cardiotoxicity. Prior studies highlighted the higher burden coronary artery disease and the importance to further assess its consequences on breast cancer patients. Purpose We sought to evaluate the revascularization rate and in-hospital short-term outcomes of breast cancer patients following acute coronary syndrome (ACS) compared to the general female population. Methods We reviewed the Nationwide Inpatient Sample from 2010 to 2014 to identify female patients with principal diagnosis of ACS (ST-elevation and non ST-elevation myocardial infarction, and unstable angina). Two subgroups were identified, women with a history of breast cancer and women without, and were propensity matched. Multivariate regression analyses were performed to evaluate the impact of breast cancer on primary outcome (in-hospital mortality) and secondary outcomes: occurrence of shock, acute kidney injury (AKI), mechanical ventilation (MV), and length of stay (LOS). We also compared the rate of cardiac procedures. Statistical significance of odd ratios (OR) is defined with p-value<0.05 and reported 95% confidence intervals (CI). Results We identified a total of 245,563 female patients with primary diagnosis of ACS, among them 10,625 (4.3%) had a history of breast cancer. The comorbidity of breast cancer was associated with statistically significant lower rates of mortality (OR 0.83, CI 0.74–0.94), shock (OR 0.87, CI 0.77–0.99), AKI (OR 0.90, CI 0.82–0.98), MV (OR 0.81, CI 0.71–0.92) and relative 5.4% decrease in LOS (CI: −7.8%, −3.0%). The cardiac procedural rates were similar for left heart catheterization (OR 0.96, CI 0.90–1.02), for percutaneous coronary intervention (OR 0.95, CI 0.89–1.02) and for CABG (OR 0.88, CI 0.78–1.00) compared to control group. Conclusion Breast cancer patients received a comparable catheterization and revascularization procedure rate and exhibited a statistically significant lower morbidity and mortality rates during hospitalization after an ACS event compared to the general female population. Funding Acknowledgement Type of funding source: None

scholarly journals NON-ST-ELEVATION ACUTE CORONARY SYNDROME DUE TO A TOTALLY OCCLUDED CORONARY ARTERY: A HISTORY OF TWO TWIN BROTHERS

2020 ◽  
Vol 73 (1) ◽  
pp. 201-202
Author(s):  
Adam Kern ◽  
Krystian Bojko ◽  
Ewa Sienkiewicz ◽  
Artur Zarzecki ◽  
Jacek Bil
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Coronary Intervention ◽  
The Other ◽  
Coronary Syndrome ◽  
Percutaneous Coronary ◽  
History Of ◽  
St Elevation ◽  
Elevation Acute Coronary Syndrome

We present the image of two twin brothers aged 53. Within 18 months they both underwent acute coronary syndrome treated with percutaneous coronary intervention (PCI). This story shows that both twins had similar comorbidities (hypercholesterolemia and hypothyroidism) as well as the course of the acute coronary syndrome. Although in both cases the coronary artery was totally occluded (in one case – fresh occlusion, in the other – CTO), no STEMI presentation was observed. Therefore, thorough investigation is warranted in twins after the acute coronary syndrome in of them, even in case of no evident ischemia symptoms.

scholarly journals Risk Factors and Trends for Incidence of Acute Coronary Syndrome after Hematopoietic Stem Cell Transplant - a 15-Year Experience with National Inpatient Sample

Blood ◽  
2019 ◽  
Vol 134 (Supplement_1) ◽  
pp. 4564-4564
Author(s):  
Jasdeep Singh Sidhu ◽  
Jeevanjot Kaur Virk ◽  
Shivani Handa ◽  
Amrendra Mandal ◽  
Sridevi Rajeeve
Keyword(s):  
Acute Coronary Syndrome ◽  
Logistic Regression ◽  
Demographic Factors ◽  
Cell Transplant ◽  
National Inpatient Sample ◽  
Hematopoietic Stem ◽  
Coronary Syndrome ◽  
Increased Risk ◽  
History Of ◽  
St Elevation

Background:Significant improvement has been noted in the outcome of patients with advanced hematologic malignancies with the advances in hematopoietic cell transplantation (HCT) techniques. However, it has been observed that patients receiving HCT have increased risk of cardiovascular disease (CVD) over time with increased risk of cardiovascular mortality. Materials and Methods:This was a retrospective observational analysis. We queried the National Inpatient Sample database from 1998 to 2012 for patients aged ≥18 years who had received HCTin the past and were admitted for non-ST-elevation acute coronary syndrome (NSTE-ACS) or ST-elevation myocardial infarction (STEMI). We performed univariate logistic regression followed by multivariate logistic regression analysis to study various demographic factors and comorbiditiesand temporal trends of ACS in these patients. Results:A total of 150,072 patients with prior history of HCT were identified, out of which 952 hospitalizations were for ACS.47.16% of these patients underwent Percutaneous CoronaryIntervention.Mean age for ACS patients was 56.98 years and 71.75% patients were male. The demographic factors found to significantly affect the incidence of ACS were increasing Age (OR 1.02, p=0.01) and Insurance(Medicare as reference)[Medicaid(OR 0.3, p=0.04), private(OR 1.66, p=0.01). Charlson Comorbidity Index (CCI) had significant correlation with incidence of ACS (CCI=1 as reference) [CCI=2(OR 0.12, p=0.00), CCI³3(OR 0.60, p=0.01)]. The Medical comorbidities found to significantly affect the outcome were Congestive Heart Failure (OR 1.53, p=0.04), COPD(OR 0.54, p=0.02), smoking(OR 2.96, p=0.00), underlying CAD (OR 39.65, p=0.00) and Pulmonary Hypertension (OR 4.01, p=0.00). A trend analysis for Incidence of ACS in patients with History of HCT showed overall decline in ACS incidence which was found to be statistically significant. (Trend p-Value 0.003). Conclusion:Our study identifiedvarious factors affecting incidence of ACS in HCT patients. We also discoveredan overall downward trend in incidence of ACSin HCT patients.Further studies need to be conducted to confirm these findings. Disclosures Rajeeve: ASH-HONORS Grant: Research Funding.

scholarly journals How to Manage a Patient with Haemophilia and ACS Requiring PCI: A Battle between Bleeding and Thrombosis

Medicina ◽  
2021 ◽  
Vol 57 (4) ◽  
pp. 352
Author(s):  
Konstantinos C. Theodoropoulos ◽  
Sofia Vakalopoulou ◽  
Maria Oikonomou ◽  
George Stavropoulos ◽  
Antonios Ziakas ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Acute Coronary Syndrome ◽  
Coronary Intervention ◽  
Management Plan ◽  
Clotting Factor ◽  
Coronary Syndrome ◽  
Percutaneous Coronary ◽  
History Of ◽  
St Elevation

We present the case of a 70-year-old man with a history of haemophilia B, who presented to our hospital with a non-ST-elevation myocardial infarction. The patient, following consultation by a haemophilia expert, was revascularized with percutaneous coronary intervention (PCI) under adequate clotting factor administration. Patients with haemophilia and acute coronary syndrome, are susceptible to periprocedural bleeding and thrombotic events during PCI, and therefore a balanced management plan should always be implemented by a multidisciplinary team.

scholarly journals A comprehensive secondary prevention benchmark (2PBM) score identifying differences in secondary prevention care in patients after acute coronary syndrome

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
Y Liu ◽  
M Haegele ◽  
S Frey ◽  
I Strebel ◽  
F Jordan ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Secondary Prevention ◽  
Patient Characteristics ◽  
St Elevation Myocardial Infarction ◽  
Internal Quality ◽  
Multivariable Logistic Regression Analysis ◽  
Coronary Syndrome ◽  
History Of ◽  
St Elevation

Abstract Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): Unrestricted grands from AstraZeneca, Boehringer Ingelheim and Sanofi Background Reaching secondary prevention targets improves long-term prognosis in patients after acute coronary syndrome (ACS). Although prevention targets are defined by guidelines, their achievement rates are insufficiently documented. Suitable benchmarking tools are lacking. Purpose  We aimed to determine the degree of secondary prevention care by creating a secondary prevention benchmark score (2PBM) and using it in patients undergoing ambulatory cardiac rehabilitation (CR) after an acute coronary syndrome.  Methods In this observational cohort study, 472 consecutive ACS patients who completed the local ambulatory CR programme between 2017-2019 were included. Benchmarks for secondary prevention medication, clinical and lifestyle targets were predefined and combined in the complete 2PBM with maximum 10 points. The association of patient characteristics and achievement rates of individual components and the complete 2PBM were assessed using multivariable logistic regression analysis.  Results Patients were on average 62 ± 11 years old and predominantly male (n = 406; 86%). Type of ACS was ST-elevation myocardial infarction (STEMI) in 241 patients (51%) and non-ST-elevation myocardial infarction in 216 patients (46%). Achievement rates for individual components of the 2PBM were 71% for medication, 35% for clinical and 61% for lifestyle benchmarks. Achievement of medication benchmark was associated with younger age [odds ratio (OR): 0.979, 95% confidence interval (CI) 0.959-0.996, p = 0.021] and history of STEMI [OR: 2.05, 95% CI 1.35-3.12, p = 0.001]. Achievement of clinical benchmark was associated with medication benchmark [OR: 1.66, 95% CI 1.03-2.71, p = 0.042]. The complete 2PBM was achieved by 74 patients (16%), while 362 patients (77%) reached ≥8 points. Achievement of complete 2PBM was independently associated with a history of STEMI [OR: 1.79, 95 CI 1.06-3.08 p = 0.032].  Conclusion Benchmarking with 2PBM identifies gaps and achievements in secondary prevention care. A history of STEMI was associated with the highest 2PBM score, suggesting best secondary prevention care in patients after STEMI. 2PBM may be used for internal quality control, comparison of cohorts and future correlation studies between CR targets and outcomes. Abstract Figure.

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