N-terminal sequences affect expression of triterpene biosynthesis enzymes in Chlamydomonas chloroplasts

2019 ◽  
Vol 44 ◽  
pp. 101662
Author(s):  
Shih-Chi Hsu ◽  
Daniel R. Browne ◽  
Mehmet Tatli ◽  
Timothy P. Devarenne ◽  
David B. Stern
Keyword(s):  
Affect Expression ◽  
Triterpene Biosynthesis

scholarly journals Chemical Phenotypes of the hmg1 and hmg2 Mutants of Arabidopsis Demonstrate the In-planta Role of HMG-CoA Reductase in Triterpene Biosynthesis

2007 ◽  
Vol 55 (10) ◽  
pp. 1518-1521 ◽  
Author(s):  
Kiyoshi Ohyama ◽  
Masashi Suzuki ◽  
Kazuo Masuda ◽  
Shigeo Yoshida ◽  
Toshiya Muranaka
Keyword(s):  
In Planta ◽  
Hmg Coa Reductase ◽  
Coa Reductase ◽  
Triterpene Biosynthesis

scholarly journals Age, segment, and horn disease affect expression of cytokines, growth factors, and receptors in the epidermis and dermis of the bovine claw

2009 ◽  
Vol 92 (12) ◽  
pp. 5977-5987 ◽  
Author(s):  
J.A. Mills ◽  
D.S. Zarlenga ◽  
P.L. Habecker ◽  
R.M. Dyer
Keyword(s):  
Growth Factors ◽  
Affect Expression

Adult Antisocial Behavior and Affect Regulation Among Primary Crack/Cocaine-Using Women

2003 ◽  
Vol 27 (2) ◽  
pp. 143-152 ◽  
Author(s):  
Lisa Caren Litt ◽  
Denise A. Hien ◽  
Deborah Levin
Keyword(s):  
Inner City ◽  
Antisocial Behavior ◽  
Affect Regulation ◽  
Crack Cocaine ◽  
Rating Scale ◽  
Emotional Experience ◽  
Primary Crack ◽  
Affect Expression ◽  
Primary Caretakers ◽  
The Relationship

The relationship between deficits in affect regulation and Adult Antisocial Behavior (ASB) in primary crack/cocaine-using women was explored in a sample of 80 inner-city women. Narrative early memories were coded for two components of affect regulation, Affect Tolerance and Affect Expression, using the Epigenetic Assessment Rating Scale (EARS; Wilson, Passik, & Kuras, 1989 ). ASB was measured by the adult criteria of Antisocial Personality Disorder on the SCID-SAC ( Spitzer, Williams, Gibbon, & First, 1993 ). Analyses compared primary crack/cocaine-using women with and without ASB on the affect regulation measures. Findings using memories of primary caretakers revealed that women with ASB had significantly poorer capacity for Affect Tolerance and Affect Expression than women without ASB, suggesting that ASB is significantly associated with differences in the capacity to regulate emotional experience among primary crack/cocaine-using women.

Non-syndromic oligodontia in siblings: A spectrum of experience

Dental Update ◽  
2021 ◽  
Vol 48 (2) ◽  
pp. 135-139
Author(s):  
Claudia Heggie ◽  
L Gartshore
Keyword(s):  
Family History ◽  
Preventive Care ◽  
Dental Care ◽  
Multidisciplinary Team ◽  
Dental Students ◽  
Permanent Teeth ◽  
Tooth Surface ◽  
Affect Expression ◽  
Relevant Family History

Non-syndromic oligodontia, the agenesis of six or more teeth, has a prevalence of 0.14–0.25%. Genetic, epigenetic and environmental influences affect expression. Three brothers presented with agenesis of 14, 21 and 23 permanent teeth, respectively. They were medically well, with no relevant family history. Each case presented with caries, microdontia and attritive tooth surface loss. Comprehensive care was delivered in each case by undergraduate dental students. Individualized prevention and stabilization were completed before referral for multidisciplinary long-term planning. Primary dental care practitioners are instrumental in delivering preventive care and stabilizing the dentition in cases of dental anomaly, while sharing care with specialist teams. CPD/Clinical Relevance: An unusual presentation of non-syndromic oligodontia relevant to primary dental care practitioners who are likely to provide the first clinical contact and referral to the wider multidisciplinary team.

Abstract 191: NF-?B p65 Methylation by Protein Arginine Methyltransferase 5 (PRMT5) is Necessary for the Transcriptional Induction of CXCL10 by TNF-a

2013 ◽  
Vol 33 (suppl_1) ◽  
Author(s):  
Daniel P Harris
Keyword(s):  
Endothelial Cells ◽  
Mrna Expression ◽  
Chromatin Immunoprecipitation ◽  
Proximal Promoter ◽  
Protein Arginine Methyltransferase ◽  
Arginine Methyltransferase ◽  
Expression Of Genes ◽  
Tnf Α ◽  
Affect Expression ◽  
Transcriptional Induction

TNF-α initiates the expression of genes involved in the recruitment, adhesion, and transmigration of leukocytes to sites of inflammation. Here, we report that the protein arginine methyltransferase PRMT5 is required for the transcriptional induction of the pro-inflammatory chemokine CXCL10 (IP-10) in endothelial cells. Depletion of PRMT5 by siRNA results in significantly diminished TNF-α-induced CXCL10 mRNA expression, but does not affect expression of other chemokines, such as MCP-1 or IL-8. Chromatin immunoprecipitation experiments of the CXCL10 proximal promoter show the presence of symmetrical dimethylated arginine (sDMA)-containing proteins upon exposure to TNF-α. This methylation is completely lost when PRMT5 is removed from cells by siRNA. Using immunoprecipitation, we show that PRMT5 enhances CXCL10 expression by methylating the RelA (p65) subunit of NF-κB. In summary, we have identified that PRMT5 is a novel regulator of CXCL10 expression. Further, we have discovered that PRMT5 methylates NF-κB, a finding which may further knowledge of the post-translational code governing NF-κB regulation and target specificity.

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