318 Comparision of the Initial Glasgow Coma Scale and Serum Cholinesterase Level to the ICU Stay in Acute Organophosporus Poisoning Presenting to a Tertiary Care Hospital in Madurai, India

Background: The objective of the study was to compare clinical patterns of head injuries in reference to the Glasgow coma scale including neurological examination and also to determine morbidity and mortality in head injury patients admitted to a nodal tertiary care hospital and a rural community hospital.Methods: This prospective study was done at the emergency department of Kasturba Hospital attached to Mahatma Gandhi Institute of Medical Sciences and Sushrut Hospital, Maharashtra on a total of 1000 cases during one-year study duration. The severity of the head injury was analysed using a Glasgow coma scale and outcome in terms of management and death was assessed.Results: Out of 1000 cases with head injuries, 900 cases were admitted in tertiary care hospital and 100 cases in a rural hospital. A significant difference was observed in terms of age group (p=0.01), mode of trauma (p=0.04) and symptoms (p=0.03) among the patients admitted with head injuries in both hospitals. The mortality rate was 1% and 3% in tertiary care and rural hospitals respectively.Conclusions: Head injuries are predominantly affecting the male population and most of them are due to road traffic accidents. Early assistance of medical aid and emergency room care results in good outcomes with minimal deaths.

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Abstract TP330: Insular Cortex Lesions are Associated With Early Mortality in Patients With Intracerebral Hemorrhage

Stroke ◽

10.1161/str.48.suppl_1.tp330 ◽

2017 ◽

Vol 48 (suppl_1) ◽

Author(s):

Luis Prats-Sánchez ◽

Fernando Fayos ◽

Elba Pascual-Goñi ◽

Celia Painous ◽

Pol Camps-Renom ◽

...

Keyword(s):

Glasgow Coma Scale ◽

Intracerebral Hemorrhage ◽

Independent Predictor ◽

Tertiary Care ◽

Insular Cortex ◽

Brain Atlas ◽

Lesion Volume ◽

Care Hospital ◽

Cox Regression Analysis ◽

Coma Scale

Introduction: Insular lesions have been described as an independent predictor of death in acute ischemic stroke. This study was undertaken to determine the influence of insular damage on the mortality of patients with intracerebral hemorrhage (ICH). Hypothesis: Insular cortex lesions are an independent predictor of death in acute ICH. Methods: This is an observational study of consecutive patients with spontaneous acute ICH who were admitted to a tertiary care hospital. The following data were collected prospectively: age, sex, traditional vascular risk factors, vital signs, CT findings (secondary intraventricular hemorrhage, hematoma volume), Glasgow Coma Scale score, time and cause of death within hospitalization. The insular cortex damage (right, left or any) was assessed by a blind evaluator using an interactive brain atlas. The association between insular lesions and mortality was investigated by use of logistic regression and Cox proportional hazards models. Results: We included 276 patients whose mean age was 77±14.3 years; 52.7% of them were men. During a median of 7 days (interquartile range 2-15) of hospitalization, 91 (32.9%) deaths were recorded. We observed 72 (26%) patients with insular cortex lesions (right insula=34, left insula=38). Cox regression analysis showed that age (adjusted hazard ratio [aHR] 1.02, 95% CI 1.00-1.04; p<0.001), Glasgow Coma Scale (aHR 0.84, 95% CI 0.80-0.89; p<0.001), lesion volume (aHR 1.10, 95% CI 1.06-1.15; p<0.001) and any insular damage (aHR 2.19, 95% CI 1.40-3.42, p=0.002) were significant predictors of death within hospitalization. Conclusions: In conclusion, insular cortex lesions adversely influence survival after spontaneous ICH. This finding was observed even after adjustment for other well-known predictors of ICH mortality.

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Demographic and clinical profile with early outcome of critically ill COVID-19 patients admitted in an ICU of a tertiary care hospital in Dhaka, Bangladesh

BIRDEM Medical Journal ◽

10.3329/birdem.v10i0.50981 ◽

2020 ◽

pp. 51-55

Author(s):

ASM Areef Ahsan ◽

Rozina Sultana ◽

Kaniz Fatema ◽

Fatema Ahmed ◽

Debasish Kumar Saha ◽

...

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Critically Ill ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Rt Pcr ◽

Demographic Profile ◽

Icu Stay ◽

Length Of Icu Stay

Background: First outbreak of corona virus disease (COVID-19) started in Wuhan, China at December 2019 and since then, it spread globally but information about critically ill patients with COVID-19 is still limited. So, it is important to know the demographic profile and overall outcome of COVID-19 patients. We aimed to describe the clinic-demographic characteristics and outcome of critically ill COVID-19 patients admitted in our intensive care unit. Methods: This prospective observational study was carried out in the intensive care unit of department of Critical Care Medicine of BIRDEM General Hospital, Dhaka, Bangladesh from 11th June to 31st October, 2020. Out of 382 suspected cases, 86 patients were found to be RT-PCR for COVID-19 positive and were included in this study. After admission in ICU, all patients were resuscitated according to ICU protocol. Length of ICU stay were recorded and patient outcomes were mentioned as survival (transferred or discharged) or death. Results: A total of 86 patients (male 53, female 33, mean age 63.6 ± 12.8 years) with RT-PCR for COVID-19 positive were enrolled in this study. Regarding COVID related symptoms, Ninety six percent(83) had respiratory distress, 93.02 % (n=80) had cough, 84.9% (n=73) had history of fever,11.6 % (n=10) had loose motion and 7% (n=6), had anosmia. Diabetes mellitus (DM) was the most common co morbidity (91.9%).For improvement of oxygenation of COVID patient, we treated 7% of patients (n=6) by nasal Cannula, 24.4% (n=21) by Face Mask, 20.9% (n=18) by Non Rebreather Mask, 22.1% (n= 19) by High Flow Nasal Cannula (HFNC) and 25.6% (n= 22) by Mechanical Ventilation. Mean length of ICU stay were 6.9 ± 3.6 days and range of icu stay were 1-20 days. Among 86 COVID patient, 51.16% (n=44) were transferred to the isolation ward or discharged at home and 48.8% (n=42) were died. Conclusion: This study showed the overall demographic and clinical features of critically ill COVID-19 patients, admitted in an icu of a tertiary care hospital. As it is a single centered study, we need more study with multi center approach to know the detail demographic profile and outcome of COVID-19 patients. Birdem Med J 2020; 10, COVID Supplement: 51-55

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Correlation of PeradeniyaOrganophosphorus Poisoning Scale (POP) and outcome of Organophosphorus poisoning

Birat Journal of Health Sciences ◽

10.3126/bjhs.v5i1.29702 ◽

2020 ◽

Vol 5 (1) ◽

pp. 986-989

Author(s):

Gunjan Regmi ◽

Batsalya Arjyal ◽

Kanak Khanal ◽

Kumud Pyakurel ◽

Rejina Shahi

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Assessment Tool ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Intensive Care Admission ◽

Icu Stay ◽

Number Of Patients ◽

Organophosphorus Poisoning

Introduction: Organophosphorus poisoning is one of the common causesfor the intensive care admission in the developing countries.This study was conducted to assess the correlation between Peradeniya Organophosphorus Poisoning (POP) scale and the outcomes in poisoningin a tertiary care hospital in Eastern Nepal. Objective: To assess the severity and outcome of OP compound poisoning with the correlation of POP score. Methodology: This was a prospective observational study conducted over 6 months in the intensive care unit at tertiary care hospital in the eastern part of Nepal. The study includedall OP poisoning patients presenting in the emergency department and finally admitted to intensive care unit who fulfilled the inclusion criteria.Correlation was made between POP scores and outcomes in terms of intensive care unit(ICU) stay, need of ventilation and mortality was assessed. Result: Fifty patients with OP poisoning wereincluded in the study. Suicide attempt was the most common reason for poisoning. The incidence of poisoning was more common among males(72%)and significant majority were aged younger than 35 years (84%). On admission, the number of patients in mild, moderate and severepoisoning group were 52%, 30% and 18% respectively. Rates for ICU stay, respiratory failure requiring ventilator and mortality was significantly (p<0.001) higher in severe POP scale. Conclusion: The POP scale is a useful clinical assessment tool to assess and categorize patients with OP poisoning according to severity and in predicting their clinical outcomes.

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Development and Implementation of an e-Learning Program on Glasgow Coma Scale

Indian Journal of Neurotrauma ◽

10.1055/s-0041-1739480 ◽

2021 ◽

Author(s):

Teenu Xavier ◽

Merin Lisa Kuriakose ◽

Metilda Robin ◽

Deepak Agrawal

Keyword(s):

Nursing Education ◽

Online Education ◽

Glasgow Coma Scale ◽

Effective Means ◽

Tertiary Care ◽

Care Hospital ◽

Learning Program ◽

Coma Scale ◽

E Learning ◽

The Mean

Abstract Background With the advancement in technology, e-learning is an attractive platform to facilitate online continuing medical education. The aim of the study was to develop a web-based nursing education program on the Glasgow coma scale (GCS) and to assess the effectiveness of this module in improving the knowledge of nurses. Methods A one-group pretest posttest study was conducted among nurses working in a tertiary care hospital in New Delhi, India, from November 2015 till July 2016. Before administering the GCS module, an online questionnaire was used to assess the baseline knowledge. After the completion of the module, a posttest questionnaire was administered and assessed. Results A total of 3500 users completed the e-learning GCS module. The mean pretest score was 4.2 ±2.1, and the mean posttest score was 7.3 ± 2.5. The mean difference in the score was statistically highly significant (p < 0.05). Conclusion The e-learning module is an effective means of providing continuing online education to the nurses, so that they can update their knowledge.

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Demographic Variables, Co morbidities and Clinical Presentation of Spontaneous Intracerebral Hemorrhage (ICH) in a tertiary Care Hospital in Bangladesh: A Cross Sectional Study

10.36811/jcri.2021.110023 ◽

2021 ◽

pp. 27-37

Author(s):

Shoriful Islam ◽

Richmond Ronald Gomes ◽

Monjur Hasan

Keyword(s):

Blood Pressure ◽

Glasgow Coma Scale ◽

Intracerebral Hemorrhage ◽

Clinical Presentation ◽

Blood Pressure Reduction ◽

Tertiary Care ◽

Care Hospital ◽

Spontaneous Intracerebral Hemorrhage ◽

Cross Sectional ◽

Coma Scale

Spontaneous intracerebral hemorrhage (ICH) has remained the least treatable form of stroke despite recent improvements in medical treatment. Treatment usually supportive and medical such as ventilatory support, blood pressure reduction, osmotherapy, fever control, seizure control and nutritional support and treatment of co morbidconditions. This study was carried out to see demographic variability, clinical presentation, causes and outcome of spontaneous intracerebral hemorrhage. Methods and Materials: This was a cross sectional observational prospective in study on 50 spontaneous ICH patients admitted in Medicine department of Khulna Medical College Hospital from November 2020 to April, 2021. Result: The study showed that spontaneous ICH was most common in between 41-70 years. Their age frequency were 14 (28%) in 41-50 years, 15 (30%) in 51-60 years, 12 (24%) in 61-70 years, 5 (10%) in 71- 80 years and 4 (8%) in more than 81 years age group. Among the patients, 64% (32) were male and 36% (18) were female. Headache, vomiting and seizure was present in 28, 27 and 8 patients respectively. Diabetes mellitus was present in 22% (11) of patients and absent in 78% (39) patients. Range of blood pressure at presentation –<140/90 in 24%(12), Systolic BP:140-159/Diastolic BP:90-99 (mm Hg) in 10%(5), Systolic BP:160-179/Diastolic BP:100-109 (mm Hg) in 22%(11),Systolic BP:180 or more/Diastolic BP:110 or more (mm Hg) in 44%(22) patients. Dyslipidemia was present in 30% (15) & absent in 70% (35) patients. Glasgow Coma Scale Score was 8 or less in 42% (21) and 9 or more in 58% (29) patients. Conclusion: Spontaneous ICH is common in Indian subcontinent. As our study showed that death occur due to ICH itself, associated co morbidities or complications, facilities for stroke care unit, high dependency unit and Intensive care unit is required in tertiary care health settings. Keyword: Spontaneous; Intracerebral Hemorrhage; Osmotherapy; Seizure; Glasgow Coma Scale

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