scholarly journals WITHDRAWN: Reversible small-molecule polymerizable phosphatidylcholine: Novel disulfide crosslinked micelles for redox-dependent drug delivery

2020 ◽  
Author(s):  
Longbing Ling ◽  
Muhammad Ismail ◽  
Xinsong Li
Keyword(s):  
Drug Delivery ◽  
Small Molecule ◽  
Crosslinked Micelles

scholarly journals Advanced and Innovative Nano-Systems for Anticancer Targeted Drug Delivery

Pharmaceutics ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1151
Author(s):  
Lu Tang ◽  
Jing Li ◽  
Qingqing Zhao ◽  
Ting Pan ◽  
Hui Zhong ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Treatment ◽  
Small Molecule ◽  
Anticancer Agents ◽  
Targeted Drug Delivery ◽  
Treatment Modalities ◽  
Biological Macromolecules ◽  
Passive Targeting ◽  
Efficient Delivery ◽  
Targeted Drug

The encapsulation of therapeutic agents into nano-based drug delivery system for cancer treatment has received considerable attention in recent years. Advancements in nanotechnology provide an opportunity for efficient delivery of anticancer drugs. The unique properties of nanoparticles not only allow cancer-specific drug delivery by inherent passive targeting phenomena and adopting active targeting strategies, but also improve the pharmacokinetics and bioavailability of the loaded drugs, leading to enhanced therapeutic efficacy and safety compared to conventional treatment modalities. Small molecule drugs are the most widely used anticancer agents at present, while biological macromolecules, such as therapeutic antibodies, peptides and genes, have gained increasing attention. Therefore, this review focuses on the recent achievements of novel nano-encapsulation in targeted drug delivery. A comprehensive introduction of intelligent delivery strategies based on various nanocarriers to encapsulate small molecule chemotherapeutic drugs and biological macromolecule drugs in cancer treatment will also be highlighted.

Small Molecule-Based Fluorescent Organic Nanoassemblies with Strong Hydrogen Bonding Networks for Fine Tuning and Monitoring Drug Delivery in Cancer Cells

Small ◽  
2018 ◽  
Vol 14 (38) ◽  
pp. 1802307 ◽  
Author(s):  
Joanna Boucard ◽  
Camille Linot ◽  
Thibaut Blondy ◽  
Steven Nedellec ◽  
Philippe Hulin ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hydrogen Bonding ◽  
Cancer Cells ◽  
Small Molecule ◽  
Fine Tuning ◽  
Monitoring Drug ◽  
Hydrogen Bonding Networks

Light-Cross-linked Enediyne Small-Molecule Micelle-Based Drug-Delivery System

2019 ◽  
Vol 11 (9) ◽  
pp. 8896-8903 ◽  
Author(s):  
Baojun Li ◽  
Yuequn Wu ◽  
Yue Wang ◽  
Mengsi Zhang ◽  
Huimin Chen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Small Molecule

Small-Molecule Probe for Sensing Serum Albumin with Consequential Self-Assembly as a Fluorescent Organic Nanoparticle for Bioimaging and Drug-Delivery Applications

2020 ◽  
Vol 3 (5) ◽  
pp. 3099-3113 ◽  
Author(s):  
Subhajit Guria ◽  
Avijit Ghosh ◽  
Priyanka Upadhyay ◽  
Manas kumar Das ◽  
Tanushree Mishra ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Serum Albumin ◽  
Small Molecule ◽  
Self Assembly ◽  
Drug Delivery Applications ◽  
Small Molecule Probe

Matrix metalloproteinase-sensitive hydrogel microparticles for pulmonary drug delivery of small molecule drugs or proteins

2015 ◽  
Vol 3 (27) ◽  
pp. 5629-5634 ◽  
Author(s):  
Emilie Secret ◽  
Kelsey E. Crannell ◽  
Stefan J. Kelly ◽  
Maria Villancio-Wolter ◽  
Jennifer S. Andrew
Keyword(s):  
Drug Delivery ◽  
Matrix Metalloproteinases ◽  
Matrix Metalloproteinase ◽  
Small Molecule ◽  
Pulmonary Drug Delivery ◽  
Hydrogel Microparticles ◽  
Small Molecule Drugs

Hydrogel microparticles sensitive to matrix metalloproteinases are studied for release of drugs and proteins into the lungs.

Lipoic acid based core cross-linked micelles for multivalent platforms: design, synthesis and application in bio-imaging and drug delivery

2017 ◽  
Vol 15 (22) ◽  
pp. 4798-4802 ◽  
Author(s):  
Jingsheng Huang ◽  
Fang Wu ◽  
Yunlong Yu ◽  
Haolong Huang ◽  
Shiyong Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Small Molecule ◽  
Lipoic Acid ◽  
Design Synthesis ◽  
Bio Imaging

Natural lipoic acid derived small-molecule amphiphiles self-assemble into micelles in water.

Optimized Metal–Organic-Framework Nanospheres for Drug Delivery: Evaluation of Small-Molecule Encapsulation

ACS Nano ◽  
2014 ◽  
Vol 8 (3) ◽  
pp. 2812-2819 ◽  
Author(s):  
Jia Zhuang ◽  
Chun-Hong Kuo ◽  
Lien-Yang Chou ◽  
De-Yu Liu ◽  
Eranthie Weerapana ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Small Molecule ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Organic Framework
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