Experimental transmission of Enteromyxum leei Diamant, Lom and Dykova, 1994 in sharpsnout sea bream, Diplodus puntazzo C. and the effect on some innate immune parameters

Background and Aim: Immune-modulating molecules mainly act on innate immune cells, which are central to early defense against invading pathogens and contribute to developing adaptive immunity. Yeast-extracted β-glucan, a model immune-modulating molecule, is widely used in several animal species; however, its effect on horse immune parameters has not been thoroughly investigated yet. This study aimed to evaluate the effects of orally administered β-glucan on selected innate immune parameters in horses. Materials and Methods: Eighteen thoroughbred horses were assigned equally into three groups as follows: One control group (no β-glucan) and two β-glucan experimental groups (one received 125 mg and the other 2 g of β-glucan per day for 28 days). Blood samples were collected before and at the end of the experiment for hematological analysis, whole blood phagocytosis, respiratory burst assays, and to assess the serum lysozyme and complement hemolytic activities. Results: At the end of the experiment, significant decreases (p<0.05) in monocyte numbers were observed in the control horses (258.8±45.9 vs. 115.3±41.5) and in those fed 125 mg/day of β-glucan (208.8±72.3 vs. 99.2±60.7), whereas a significant increase in numbers was noted in the horses that were fed 2 g/day of β-glucan (303.5±45.8 vs. 429.8±86.0; p<0.05). The natural hemolytic activity of the complement was higher only in horses fed 2 g/day of β-glucan (p=0.018) compared to the other groups. The hemolytic activity in the classical pathway was higher in those fed 125 mg/day (p=0.0035) and 2 g/day of β-glucan (p=0.0001). Conclusion: β-glucan improves important innate immune parameters and might be fed to horses before stressful events.

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Tissue distribution and residue depletion of oxolinic acid in gilthead sea bream (Sparus aurata) and sharpsnout sea bream (Diplodus puntazzo) following multiple in-feed dosing

Aquaculture ◽

10.1016/s0044-8486(03)00213-8 ◽

2003 ◽

Vol 224 (1-4) ◽

pp. 245-256 ◽

Cited By ~ 19

Author(s):

George Rigos ◽

Ioannis Nengas ◽

Maria Alexis ◽

Athanassios E. Tyrpenou ◽

Gera M. Troisi

Keyword(s):

Tissue Distribution ◽

Sparus Aurata ◽

Oxolinic Acid ◽

Gilthead Sea Bream ◽

Sea Bream ◽

Diplodus Puntazzo ◽

Residue Depletion

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Corrigendum to “The modulatory effect of mannanoligosaccharide on oxidative status, selected immune parameters and tolerance against low salinity stress in red sea bream (Pagrus major)” [Aquacult. Rep. 16 March (2020) 100278]

Aquaculture Reports ◽

10.1016/j.aqrep.2020.100317 ◽

2020 ◽

Vol 18 ◽

pp. 100317

Author(s):

Mahmoud A.O. Dawood ◽

Shunsuke Koshio ◽

Sabreen E. Fadl ◽

Hamada A. Ahmed ◽

Amel El Asely ◽

...

Keyword(s):

Red Sea ◽

Salinity Stress ◽

Oxidative Status ◽

Sea Bream ◽

Red Sea Bream ◽

Pagrus Major ◽

Low Salinity ◽

Immune Parameters

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Effects of stocking density on stress response, innate immune parameters, and welfare of turbot (Scophthalmus maximus)

Aquaculture International ◽

10.1007/s10499-019-00413-2 ◽

2019 ◽

Vol 27 (6) ◽

pp. 1599-1612 ◽

Cited By ~ 2

Author(s):

Baoliang Liu ◽

Fan Fei ◽

Xiaotian Li ◽

Xinyi Wang ◽

Bin Huang

Keyword(s):

Stress Response ◽

Stocking Density ◽

Scophthalmus Maximus ◽

Innate Immune ◽

Immune Parameters ◽

Turbot Scophthalmus Maximus

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Acute hypercortisolemia inhibits innate immune parameters in Piaractus mesopotamicus experimentally infected with Aeromonas hydrophila

Aquaculture ◽

10.1016/j.aquaculture.2020.735231 ◽

2020 ◽

Vol 523 ◽

pp. 735231 ◽

Cited By ~ 1

Author(s):

Victor Alexander Cueva-Quiroz ◽

Jefferson Yunis-Aguinaga ◽

Fernando Carlos Ramos-Espinoza ◽

Flávio Ruas de Moraes ◽

Julieta Rodini Engrácia de Moraes

Keyword(s):

Aeromonas Hydrophila ◽

Innate Immune ◽

Piaractus Mesopotamicus ◽

Immune Parameters

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Association study of rs1801282 PPARG gene polymorphism and immune cells and cytokine levels in a Spanish pregnant women cohort and their offspring

Journal of Biomedical Science ◽

10.1186/s12929-020-00694-3 ◽

2020 ◽

Vol 27 (1) ◽

Author(s):

Maria García-Ricobaraza ◽

Mercedes García-Bermúdez ◽

Francisco J. Torres-Espinola ◽

M. Teresa Segura Moreno ◽

Mathieu N. Bleyere ◽

...

Keyword(s):

Immune System ◽

Gene Polymorphism ◽

Cord Blood ◽

Pregnant Women ◽

Venous Blood ◽

Innate Immune ◽

Peroxisome Proliferator ◽

Blood Samples ◽

Inflammatory Reactions ◽

Immune Parameters

Abstract Background Peroxisome proliferator activated receptor gamma (PPARG) belongs to the nuclear receptor superfamily functioning as transcription factors to regulate cellular differentiation, development and metabolism. Moreover, it has been implicated in the regulation of lipid metabolism, as well as the maturation of monocytes/macrophages and the control of inflammatory reactions. The aim of this study was to evaluate the relationship between the Pro12Ala (rs1808212) PPARG gene polymorphism on immune molecular and cellular components in mothers and their offspring participating in the PREOBE study. Methods DNA from maternal venous blood samples at 24, 34 and 40 gestational weeks, plus cord blood samples was extracted. Pro12Ala PPARG polymorphism genotyping was performed, and immune system markers were analyzed by flow cytometry. Results Study findings revealed no effect of rs1808212 PPARG genotypes on innate immune parameters in mothers and their offspring; however, CD4 + /CD8 + ratio were decreased at 24 and 34 weeks in pregnant women carrying the CG (Pro12Ala) rs1808212 polymorphism, (p = 0,012 and p = 0,030; respectively). Only CD19 levels in peripheral blood were significantly higher at delivery in pregnant women carrying the CC (Pro12Pro) genotype (p ≤ 0.001). Moreover, there were statistically significant differences in leukocytes and neutrophils maternal levels at 34 weeks of gestation, being lower in carriers of Pro12Ala genotype (p = 0.028 and p = 0.031, respectively). Conclusions Results suggest that Pro12Ala PPARG polymorphism may have an effect on some cell and immune parameters in pregnant women during pregnancy and at time of delivery. However, newborn innate immune system does not seems to be influenced by PPARG Pro12Ala polymorphism in cord blood.

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