Monitoring the self-assembly of chitosan/glutaraldehyde/cysteamine/Au-colloid and the binding of human serum albumin with hesperidin

Biomaterials ◽  
2004 ◽  
Vol 25 (26) ◽  
pp. 5725-5733 ◽  
Author(s):  
Yingju Liu ◽  
Yanling Li ◽  
Shanchao Liu ◽  
Jia Li ◽  
Shouzhuo Yao
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Self Assembly ◽  
The Self

Paclitaxel-induced formation of 3D nanocrystal superlattices within injectable protein-based hybrid nanoparticles

2018 ◽  
Vol 54 (82) ◽  
pp. 11586-11589
Author(s):  
Jeong Yu Lee ◽  
Ho Yeon Son ◽  
Jae Chul Park ◽  
Jongnam Park ◽  
Yoon Sung Nam
Keyword(s):  
Polyethylene Glycol ◽  
Iron Oxide ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Self Assembly ◽  
Three Dimensional ◽  
Superparamagnetic Iron Oxide ◽  
Hybrid Nanoparticles ◽  
Nanocrystal Superlattices

Self-assembly of monodisperse superparamagnetic iron oxide nanocrystals into a close-packed, three-dimensional (3D) superlattice is designed within cross-linked protein-based nanoparticles composed of human serum albumin and polyethylene glycol.

Microfluidic self-assembly of high cabazitaxel loading albumin nanoparticles

Nanoscale ◽  
2020 ◽  
Vol 12 (32) ◽  
pp. 16928-16933
Author(s):  
Yating Sun ◽  
Robert J. Lee ◽  
Fanchao Meng ◽  
Guiyuan Wang ◽  
Xiaolong Zheng ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Self Assembly ◽  
Promising Method ◽  
Albumin Nanoparticles ◽  
Microfluidic Technology

Microfluidic technology for the preparation of human serum albumin nanoparticles is a promising method.

Self-Assembled N-Succinyl-Chitosan Nanofibers for Reduced Protein Adhesion

2010 ◽  
Vol 76 ◽  
pp. 36-41
Author(s):  
Eyas Dayyoub ◽  
Udo Bakowsky
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Self Assembly ◽  
Adhesion Properties ◽  
Force Microscopy ◽  
Atomic Force ◽  
Biomaterial Surfaces ◽  
Force Curves ◽  
Protein Adhesion

Protein adhesion on biomaterial surfaces plays a major role in determining their biocompatibility and cell responses. The goal of this study was to produce chitosan-based coatings of implant material polyurethane (PUR) for reduced human serum albumin (HSA) adhesion. Succinic anhydride was employed for modifying chitosan and synthesis of N-succinyl-chitosan (NSCS) which was used as a matrix coating of PUR. NSCS showed self-assembly behaviour as nanofiber structures onto PUR surface. Atomic force microscopy (AFM) has emerged as useful tool for the molecular force measurements and therefore it has been chosen to investigate the adhesion properties of Human serum albumin (HSA) on the new matrix coatings and other three implant materials PUR, Silicon and Titanium. HSA molecules were covalently bound to the AFM tip by the use of cyanuric chloride as bivalent linker. Analyzing the force curves demonstrated the antiadhesive properties of the NSCS films in comparison with the uncoated PUR, Silicon and Titanium.

scholarly journals Protein Nanoparticles Formed by Self-assembly of Human Serum Albumin with a Fatty Acid Arm

2020 ◽  
Vol 49 (1) ◽  
pp. 103-106
Author(s):  
Yoshitsugu Morita ◽  
Daiki Takahashi ◽  
Teruyuki Komatsu
Keyword(s):  
Fatty Acid ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Self Assembly ◽  
Protein Nanoparticles

Human Serum Albumin Self-Assembly on Weak Polyelectrolyte Multilayer Films Structurally Modified by pH Changes

Langmuir ◽  
2004 ◽  
Vol 20 (13) ◽  
pp. 5575-5582 ◽  
Author(s):  
Csilla Gergely ◽  
Sophie Bahi ◽  
Balázs Szalontai ◽  
Hector Flores ◽  
Pierre Schaaf ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Self Assembly ◽  
Multilayer Films ◽  
Polyelectrolyte Multilayer ◽  
Ph Changes

scholarly journals Self-assembly of nanoparticles by human serum albumin and photosensitizer for targeted near-infrared emission fluorescence imaging and effective phototherapy of cancer

2019 ◽  
Vol 7 (7) ◽  
pp. 1149-1159 ◽  
Author(s):  
Yan Huang ◽  
Na He ◽  
Yunqing Wang ◽  
Dazhong Shen ◽  
Qi Kang ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Fluorescence Imaging ◽  
Self Assembly ◽  
Near Infrared ◽  
Infrared Emission ◽  
Near Infrared Emission

A self-assembly nanoplatform of HSA@Cy-HPT for targeted near-infrared emission fluorescence imaging and effective phototherapy of cancer.

scholarly journals Detection of thioredoxin-1 using ultra-sensitive ELISA with enzyme-encapsulated human serum albumin nanoparticle

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Myeong-Jun Lee ◽  
Eun-Sol Lee ◽  
Tae-Hwan Kim ◽  
Ju-Won Jeon ◽  
YongTae Kim ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Self Assembly ◽  
Sandwich Elisa ◽  
Protein A ◽  
High Sensitivity ◽  
Enzyme Linked Immunosorbent Assay ◽  
Synthesis Conditions ◽  
Thioredoxin 1

AbstractMany methods for early diagnosis of the disease use biomarker tests, which measure indicators of biological state in body fluids or blood. However, a limitation of these methods is their low sensitivity to biomarkers. In this study, human serum albumin (HSA) based nanoparticles capable of encapsulating excess horseradish peroxidase (HRP) are synthesized and applied to the development of enzyme-linked immunosorbent assay (ELISA) kit with ultra-high sensitivity. The size of the nanoparticles and the amount of encapsulated enzyme are controlled by varying the synthesis conditions of pH and protein concentration, and the surface of the nanoparticles is modified with protein A (proA) to immobilize antibodies to the nanoparticles by self-assembly. Using the synthesized nanoparticles, the biomarker of breast cancer, thioredoxin-1, can be measured in the range of 10 fM to 100 pM by direct sandwich ELISA, which is 105 times more sensitive than conventional methods.

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