Bisphenol A alters volatile fatty acids accumulation during sludge anaerobic fermentation by affecting amino acid metabolism, material transport and carbohydrate-active enzymes

2021 ◽  
Vol 323 ◽  
pp. 124588
Author(s):  
Xiupeng Jiang ◽  
Yuanyuan Yan ◽  
Leiyu Feng ◽  
Feng Wang ◽  
Yingqing Guo ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Amino Acid ◽  
Bisphenol A ◽  
Amino Acid Metabolism ◽  
Volatile Fatty Acids ◽  
Acid Metabolism ◽  
Anaerobic Fermentation ◽  
Material Transport ◽  
Carbohydrate Active Enzymes

scholarly journals Effect of Huangqin Tang on Urine Metabolic Profile in Rats with Ulcerative Colitis Based on UPLC-Q-Exactive Orbitrap MS

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Dunfang Wang ◽  
Xuran Ma ◽  
Shanshan Guo ◽  
Yanli Wang ◽  
Tao Li ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Fatty Acids ◽  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Unsaturated Fatty Acids ◽  
Tricarboxylic Acid Cycle ◽  
Tca Cycle ◽  
Q Exactive ◽  
Therapeutic Mechanisms

As a classic prescription, Huangqin Tang (HQT) has been widely applied to treat ulcerative colitis (UC), although its pharmacological mechanisms are not clear. In this study, urine metabolomics was first analysed to explore the therapeutic mechanisms of HQT in UC rats induced by TNBS. We identified 28 potential biomarkers affected by HQT that might cause changes in urine metabolism in UC rats, mapped the network of metabolic pathways, and revealed how HQT affects metabolism of UC rats. The results showed that UC affects amino acid metabolism and biosynthesis of unsaturated fatty acids and impairs the tricarboxylic acid cycle (TCA cycle). UC induced inflammatory and gastrointestinal reactions by inhibiting the transport of fatty acids and disrupting amino acid metabolism. HQT plays key roles via regulating the level of biomarkers in the metabolism of amino acids, lipids, and so on, normalizing metabolic disorders. In addition, histopathology and other bioinformatics analysis further confirm that HQT altered UC rat physiology and pathology, ultimately affecting metabolic function of UC rats.

Essential polyunsaturated fatty acids in plasma and erythrocytes of children with inborn errors of amino acid metabolism

2006 ◽  
Vol 88 (2) ◽  
pp. 159-165 ◽  
Author(s):  
H. Vlaardingerbroek ◽  
G. Hornstra ◽  
T.J. de Koning ◽  
J.A.M. Smeitink ◽  
H.D. Bakker ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Amino Acid ◽  
Polyunsaturated Fatty Acids ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
Inborn Errors

Effect of bisphenol A exposure during gestation and lactation on amino acid metabolism in the rat brain of offspring

2010 ◽  
Vol 68 ◽  
pp. e119 ◽  
Author(s):  
Hirokazu Mizokawa ◽  
George Kokubu ◽  
Shinichi Sakamoto ◽  
Tomoyuki Kanamatsu
Keyword(s):  
Amino Acid ◽  
Bisphenol A ◽  
Rat Brain ◽  
Amino Acid Metabolism ◽  
Acid Metabolism

Dose–response effects of free fatty acids on amino acid metabolism and ureagenesis

2008 ◽  
Vol 192 (3) ◽  
pp. 369-379 ◽  
Author(s):  
L. C. Gormsen ◽  
J. Gjedsted ◽  
S. Gjedde ◽  
H. Nørrelund ◽  
J. S. Christiansen ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Amino Acid ◽  
Free Fatty Acids ◽  
Dose Response ◽  
Amino Acid Metabolism ◽  
Acid Metabolism

Amino Acid Metabolism

1979 ◽  
Vol 7 (1) ◽  
pp. 261-262
Author(s):  
E. V. ROWSELL
Keyword(s):  
Amino Acid ◽  
Amino Acid Metabolism ◽  
Acid Metabolism
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