Agarose drug delivery systems upgraded by surfactants inclusion: Critical role of the pore architecture

2014 ◽  
Vol 103 ◽  
pp. 359-368 ◽  
Author(s):  
T. Marras-Marquez ◽  
J. Peña ◽  
M.D. Veiga-Ochoa
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Critical Role ◽  
Delivery Systems ◽  
Pore Architecture

scholarly journals Nanotechnology-Based Drug Delivery to Improve the Therapeutic Benefits of NRF2 Modulators in Cancer Therapy

Antioxidants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 685
Author(s):  
Zerrin Sezgin-Bayindir ◽  
Sonia Losada-Barreiro ◽  
Carlos Bravo-Díaz ◽  
Matej Sova ◽  
Julijana Kristl ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery Systems ◽  
Critical Role ◽  
Delivery Systems ◽  
Related Factor ◽  
New Horizons ◽  
Therapeutic Benefits ◽  
Anticancer Treatment

The disadvantages of conventional anticancer drugs, such as their low bioavailability, poor targeting efficacy, and serious side effects, have led to the discovery of new therapeutic agents and potential drug delivery systems. In particular, the introduction of nano-sized drug delivery systems (NDDSs) has opened new horizons for effective cancer treatment. These are considered potential systems that provide deep tissue penetration and specific drug targeting. On the other hand, nuclear factor erythroid 2-related factor 2 (NRF2)-based anticancer treatment approaches have attracted tremendous attention and produced encouraging results. However, the lack of effective formulation strategies is one of the factors that hinder the clinical application of NRF2 modulators. In this review, we initially focus on the critical role of NRF2 in cancer cells and NRF2-based anticancer treatment. Subsequently, we review the preparation and characterization of NDDSs encapsulating NRF2 modulators and discuss their potential for cancer therapy.

Emerging Role of Colloidal Drug Delivery Systems (CDDS) in NSAID Topical Administration

2013 ◽  
Vol 20 (14) ◽  
pp. 1847-1857 ◽  
Author(s):  
Carmelo Puglia ◽  
Giorgia Tirendi ◽  
Francesco Bonina
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Topical Administration ◽  
Delivery Systems

Role of novel drug delivery systems in coronavirus disease-2019 (covid-19): time to act now

2020 ◽  
Vol 17 ◽  
Author(s):  
Neeraj Mittal ◽  
Varun Garg ◽  
Sanjay Kumar Bhadada ◽  
O. P. Katare
Keyword(s):  
Drug Delivery ◽  
Targeted Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
World Health ◽  
Ongoing Research ◽  
Standard Drug ◽  
Corona Virus ◽  
Novel Drug

: The corona virus disease 2019 (COVID-19) has found its roots from Wuhan (China). COVID-19 is caused by a novel corona virus SARS-CoV2, previously named as 2019-nCoV. COVID-19 has spread across the globe and declared as pandemic by World health organization (WHO) on 11th March, 2020. Currently, there is no standard drug or vaccine available for the treatment, so repurposing of existing drugs is the only solution. Novel drug delivery systems (NDDS) will be boon for the repurposing of drugs. The role of various NDDS in repurposing of existing drugs for treatment of various viral diseases and their relevance in COVID-19 has discussed in this paper. It focuses on the currently ongoing research in the implementation of NDDS in COVID-19. Moreover it describes the role of NDDS in vaccine development for COVID-19. This paper also emphasizes how NDDS will help to develop the improved delivery systems (dosage forms) of existing therapeutic agents and also explore the new insights to find out the void spaces for a potential targeted delivery. So in these tough times, NDDS and nanotechnology can be a safeguard to humanity.

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