Comprehensive properties of photodynamic antibacterial film based on κ-Carrageenan and curcumin-β-cyclodextrin complex

2022 ◽  
pp. 119112
Author(s):  
Danning Lai ◽  
Feng Zhou ◽  
Arong Zhou ◽  
Siti Sarah Hamza ◽  
Yi Zhang ◽  
...  
Keyword(s):  
Cyclodextrin Complex ◽  
Comprehensive Properties

Injectable in-situ Forming Depot Of Doxycycline Hyclate/α-Cyclodextrin Complex using PLGA for Periodontitis Treatment: Preparation, Charac-terization, and In-Vitro Evaluation

2020 ◽  
Vol 17 ◽  
Author(s):  
Elham Khodaverdi ◽  
Farhad Eisvand ◽  
Mohammad Sina Nezami ◽  
Seyedeh Nesa Rezaeian Shiadeh ◽  
Hossein Kamali ◽  
...  
Keyword(s):  
Complex Form ◽  
Docking Studies ◽  
Morphological Properties ◽  
Burst Release ◽  
Cyclodextrin Complex ◽  
Doxycycline Hyclate ◽  
Scanning Calorimetry ◽  
In Situ Forming

Background:: Doxycycline (DOX) is used in treating a bacterial infection, especially for periodontitis treatment. Objective: To reduce irritation of DOX for subgingival administration and increase the chemical stability and against enzy-matic, the complex of α-cyclodextrin with DOX was prepared and loaded into injectable in situ forming implant based on PLGA. Methods:: FTIR, molecular docking studies, X-ray diffraction, and differential scanning calorimetry was performed to char-acterize the DOX/α-cyclodextrin complex. Finally, the in-vitro drug release and modeling, morphological properties, and cellular cytotoxic effects were also evaluated. Results:: The stability of DOX was improved with complex than pure DOX. The main advantage of the complex is the al-most complete release (96.31 ± 2.56 %) of the drug within 14 days of the implant, whereas in the formulation containing the pure DOX and the physical mixture the DOX with α-cyclodextrin release is reached to 70.18 ± 3.61 % and 77.03 ± 3.56 %, respectively. This trend is due to elevate of DOX stability in the DOX/ α-cyclodextrin complex form within PLGA implant that confirmed by the results of stability. Conclusion:: Our results were indicative that the formulation containing DOX/α-cyclodextrin complex was biocompatible and sustained-release with minimum initial burst release.

scholarly journals Failure Analysis on a Collapsed Flat Cover of an Adjustable Ballast Tank Used in Deep-Sea Submersibles

2019 ◽  
Vol 9 (23) ◽  
pp. 5258
Author(s):  
Fang Wang ◽  
Mian Wu ◽  
Genqi Tian ◽  
Zhe Jiang ◽  
Shun Zhang ◽  
...  
Keyword(s):  
Deep Sea ◽  
Material Selection ◽  
High Strength ◽  
External Pressure ◽  
Element Analysis ◽  
Ballast Tank ◽  
Material Inhomogeneity ◽  
Comprehensive Properties ◽  
Ultimate Cause ◽  
Flat Cover

A flat cover of an adjustable ballast tank made of high-strength maraging steel used in deep-sea submersibles collapsed during the loading process of external pressure in the high-pressure chamber. The pressure was high, which was the trigger of the collapse, but still considerably below the design limit of the adjustable ballast tank. The failure may have been caused by material properties that may be defective, the possible stress concentration resulting from design/processing, or inappropriate installation method. The present paper focuses on the visual inspections of the material inhomogeneity, ultimate cause of the collapse of the flat cover in pressure testing, and finite element analysis. Special attention is paid to the toughness characteristics of the material. The present study demonstrates the importance of material selection for engineering components based on the comprehensive properties of the materials.

Rapid Clearance of IR783 and Methyl‐β‐cyclodextrin Complex for Improved Tumor Imaging

2021 ◽  
pp. 2100068
Author(s):  
Wonbong Lim ◽  
Gayoung Jo ◽  
Bo Young Lee ◽  
Min Ho Park ◽  
Hoon Hyun
Keyword(s):  
Tumor Imaging ◽  
Cyclodextrin Complex ◽  
Rapid Clearance

scholarly journals Heat Treatment-Induced Microstructure and Property Evolution of Mg/Al Intermetallic Compound Coatings Prepared by Al Electrodeposition on Mg Alloy from Molten Salt Electrolytes

Materials ◽  
2021 ◽  
Vol 14 (6) ◽  
pp. 1407
Author(s):  
Tianyu Yao ◽  
Kui Wang ◽  
Haiyan Yang ◽  
Haiyan Jiang ◽  
Jie Wei ◽  
...  
Keyword(s):  
Heat Treatment ◽  
Intermetallic Compound ◽  
Intermetallic Compounds ◽  
Mg Alloy ◽  
X Ray Diffraction ◽  
Electron Backscattered Diffraction ◽  
Alloy Matrix ◽  
Comprehensive Properties ◽  
Compound Coatings ◽  
Compound Coating

A method of forming an Mg/Al intermetallic compound coating enriched with Mg17Al12 and Mg2Al3 was developed by heat treatment of electrodeposition Al coatings on Mg alloy at 350 °C. The composition of the Mg/Al intermetallic compounds could be tuned by changing the thickness of the Zn immersion layer. The morphology and composition of the Mg/Al intermetallic compound coatings were characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD), and electron backscattered diffraction (EBSD). Nanomechanical properties were investigated via nano-hardness (nHV) and the elastic modulus (EIT), and the corrosion behavior was studied through hydrogen evolution and potentiodynamic (PD) polarization. The compact and uniform Al coating was electrodeposited on the Zn-immersed AZ91D substrate. After heat treatment, Mg2Al3 and Mg17Al12 phases formed, and as the thickness of the Zn layer increased from 0.2 to 1.8 μm, the ratio of Mg2Al3 and Mg17Al12 varied from 1:1 to 4:1. The nano-hardness increased to 2.4 ± 0.5 GPa and further improved to 3.5 ± 0.1 GPa. The Mg/Al intermetallic compound coating exhibited excellent corrosion resistance and had a prominent effect on the protection of the Mg alloy matrix. The control over the ratio of intermetallic compounds by varying the thickness of the Zn immersion layer can be an effective approach to achieve the optimal comprehensive performance. As the Zn immersion time was 4 min, the obtained intermetallic compounds had relatively excellent comprehensive properties.

Effects of Sintering Conditions on Properties of a Warm Compacted Stainless Steel Powder

2012 ◽  
Vol 217-219 ◽  
pp. 483-486
Author(s):  
Mei Yuan Ke
Keyword(s):  
Tensile Strength ◽  
Stainless Steel ◽  
Sintered Density ◽  
Sintering Temperature ◽  
Steel Powder ◽  
Stainless Steel Powder ◽  
Sintering Atmosphere ◽  
Comprehensive Properties ◽  
Ammonia Atmosphere ◽  
Sintering Conditions

Effects of Sintering atmosphere and temperature on properties of warm compacted 410L stainless steel powder were studied. Sintered density, hardness, tensile strength and elongation were measured. Results showed that in order to achieve high comprehensive properties, the optimal sintering temperature was 1230°C for 410L stainless steel powder. At the same sintering temperature, density and hardness sintered in vacuum were much higher than that sintered in cracked ammonia while tensile strength sintered in cracked ammonia were much higher than that in vacuum. When sintered in vacuum at 1230°C, sintered density was 7.45 g•cm-3, hardness was 65 HRB, tensile strength was 410 MPa and elongation was 29.5%. When sintered in cracked ammonia atmosphere at 1230°C, sintered density was 7.26 g•cm-3, hardness was 97 HRB, tensile strength was 515 MPa and elongation was 3.8%.

Riboflavin sensitized photodegradation of Furaneol in a β-cyclodextrin complex

2021 ◽  
Vol 411 ◽  
pp. 113188
Author(s):  
Carolina Gambetta ◽  
Agustina Reynoso ◽  
José Natera ◽  
Matías I. Sancho ◽  
Paulina Montaña ◽  
...  
Keyword(s):  
Cyclodextrin Complex

scholarly journals Mechanism of Electromagnetic Field in the Sub-RapidSolidification of High-Strength Al-Cu-Li Alloy Produced by Twin-Roll Casting

Metals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 952
Author(s):  
Shiju Li ◽  
Bowen Wei ◽  
Wei Yu ◽  
Chen He ◽  
Yong Li ◽  
...  
Keyword(s):  
Body Force ◽  
High Strength ◽  
Solidification Structure ◽  
Experimental Characterization ◽  
Alloy Plate ◽  
Twin Roll Casting ◽  
Comprehensive Properties ◽  
Roll Casting ◽  
Mold Casting ◽  
Twin Roll

In this work, a Al-Cu-Li alloy plate with outstanding mechanical properties was successfully prepared with electromagnetic twin-roll casting (TRC) technology. The microstructure of Al-Cu-Li alloy manufactured by conventional mold casting, TRC, and electromagnetic TRC was studied in detail. The action mechanism of electromagnetic oscillation field (EOF) in the TRC process was studied by systematic experimental characterization and numerical simulation. The results show that the EOF will enlarge the circumfluence area in the cast-rolling zone, accelerate the mass transfer and heat transfer in the molten pool, and make the solute field and flow field in the liquid cavity tend to be evenly distributed. Further, the introduction of the EOF will produce the electromagnetic body force F with the maximum strength of 14 N/m3. The F acting on the solidification front will eliminate the accumulation and deposition of Cu2+, Li+, Mg2+, Zn2+, Mn2+ at the dendrite tip and inhibit the growth of dendrites. At the same time, the F can refine the microstructure of the TRC plate, promote the formation of equiaxed crystals, improve the supersaturated solid solubility of solute elements in the a(Al) matrix, and avoid the appearance of obvious solute segregation area or the formation of excessive solute enrichment area. Therefore, the macro-segregation in TRC plate was significantly reduced, the solidification structure was dramatically refined, and the comprehensive properties of the alloy were remarkably improved.

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