Testosterone Level Does Not Affect the Risk of Admission or Length of Hospital Stay in Patients with Heart Failure — A National Health and Nutrition Examination Survey-Based Study

To examine the associations of heart failure (HF) with five domains of disability while controlling for covariates. Subjects with HF and aged ≥ 50 years were selected from the 1999 to 2018 National Health and Nutrition Examination Survey data. Five domains of disability were measured with 19 physical tasks. Logistic regression with adjustment for covariates was conducted. The prevalence of HF in 27,185 adults aged ≥ 50 years was 6.37%. After controlling for demographics and smoking, logistic regression showed that HF was associated with 2.8 to 3.4 times increased odds of all domains of disability compared to adults without HF, but with additional adjustments of covariates, the association was attenuated indicating the mediating effects of covariates. The future study may examine the mediating effects of covariates when intervening difficulties with lower extremity mobility and activities of daily living while considering in community-dwelling older adults with HF.

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Abstract 15214: Food Insecurity and Cardiovascular Disease in NHANES (National Health and Nutrition Examination Survey) 2011-2016

Circulation ◽

10.1161/circ.142.suppl_3.15214 ◽

2020 ◽

Vol 142 (Suppl_3) ◽

Author(s):

MONICA M DELSON ◽

Janice F Bell ◽

Tequila S Porter ◽

Julie T Bidwell

Keyword(s):

Heart Failure ◽

Cardiovascular Disease ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Food Insecurity ◽

National Health ◽

The United States ◽

Nutrition Examination Survey ◽

Health And Nutrition ◽

Artery Disease

Background: Adherence to a heart-healthy diet is foundational for the prevention, management, and treatment of cardiovascular disease (CVD). Despite the fact that adhering to dietary guidelines may be challenging in the context of food insecurity, little is known about the likelihood of food insecurity in persons with CVD. Hypothesis: We hypothesized that persons with CVD (hypertension, coronary artery disease, heart failure, or stroke) would have significantly higher odds of food insecurity. Methods: This was an analysis of data from the National Health and Nutrition Examination Survey (NHANES), a nationally representative, cross-sectional study of health in the United States. All adults aged 19 years or older with food insecurity data were included across 3 cycles of NHANES (2011-2016). Food insecurity was measured using the 10-item Food Security Scale. CVD diagnosis was measured by self-report. Risk for food insecurity by CVD diagnosis was examined using multivariable logistic regression models, incorporating NHANES sample and person weights, and controlling for common sociodemographic confounders (age, gender, race/ethnicity, education, marital status). Results: The sample consisted of 17,175 persons (weighted study N =229,247,659). Slightly more than half were male (51.9%), and most were non-Hispanic white (65.1%). Just under half (45.6%) were in early adulthood (19-44 years), 35.3% were in middle adulthood (45-64 years), and 18.6% were in late adulthood (≥65 years). One quarter (25.9%) were food insecure. Consistent with our hypothesis, diagnosis of any CVD (stroke, heart failure, coronary artery disease, or hypertension) was significantly associated with higher likelihood for food insecurity (stroke: OR=2.18; 95% CI 1.83-2.60; p<0.001; heart failure OR=1.94, 95% CI 1.46-2.57, p<0.001; coronary artery disease: OR=1.90, 95% CI 1.49-2.43, p<0.001; and hypertension: OR=1.25, 95% CI 1.10-1.42, p=0.001). Conclusions: Diagnoses of hypertension, stroke, coronary artery disease, and heart failure were all significantly associated with higher risk for food insecurity. Given the necessity of dietary modification in CVD, further efforts to study food insecurity in CVD alongside other social determinants of health are urgently needed.

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Elevated Serum Uric Acid and Self-Reported Heart Failure in US Adults: 2007–2016 National Health and Nutrition Examination Survey

Cardiorenal Medicine ◽

10.1159/000502438 ◽

2019 ◽

Vol 9 (6) ◽

pp. 344-353 ◽

Cited By ~ 1

Author(s):

Michelle L. Stone ◽

Michael R. Richardson ◽

Larry Guevara ◽

Bethany G. Rand ◽

James R. Churilla

Keyword(s):

Heart Failure ◽

Uric Acid ◽

Serum Uric Acid ◽

National Health ◽

Representative Sample ◽

Elevated Serum ◽

Activity Level ◽

Nutrition Examination Survey ◽

Men And Women ◽

Health And Nutrition

Introduction: There is limited evidence examining the relationship between elevated serum uric acid (sUA) concentration and heart failure (HF) in United States (US) adults. The aim of the present study was to examine the association(s) between elevated sUA and HF using a nationally representative sample of US adults. Methods: The final sample with complete data for this analysis (n = 17,349) included men and women aged ≥40 years who participated in the 2007–2016 National Health and Nutrition Examination Survey. Self-reported diagnosis of HF was assessed via interview. Elevated sUA was defined as values >6.0 mg/dL for women and >7.2 mg/dL for men. Multivariable gender-stratified logistic regression was utilized to examine the odds of self-reported HF. Results: The estimated prevalence of HF was 3.9 and 3.4% among men and women, respectively. Age-adjusted analysis revealed significantly increased odds of HF in men (OR 2.79; 95% CI 2.15–3.84, p < 0.01) and women (OR 3.24; 95% CI 2.37–4.44, p < 0.01) with elevated sUA. This relationship remained statistically significant following adjustment for age, race, education, income, alcohol consumption, smoking status, blood pressure, diabetes, physical activity level, cholesterol, creatinine level, and body mass index in men (OR 1.70; 95% CI 1.13–2.57 p < 0.05) and women (OR 1.74; 95% CI 1.18–2.58, p < 0.05). Conclusions: In a representative sample of US adults, having an elevated sUA concentration was associated with significantly increased odds of HF when compared to adults with normal sUA.

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5 The Impact of Psychiatric Comorbidities on the Length of Hospital Stay in Patients with Heart Failure

Heart ◽

10.1136/heartjnl-2016-309890.5 ◽

2016 ◽

Vol 102 (Suppl 6) ◽

pp. A4-A5

Author(s):

Paul Carter ◽

Andrew Carter ◽

Jennifer Reynolds ◽

Hardeep Uppal ◽

Suresh Chandran ◽

...

Keyword(s):

Heart Failure ◽

Hospital Stay ◽

Length Of Hospital Stay ◽

Psychiatric Comorbidities ◽

Patients With Heart Failure ◽

The Impact

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Heart failure and inflammation: results from the third national health and nutrition examination survey (NHANES III)

Journal of Cardiac Failure ◽

10.1016/j.cardfail.2004.06.275 ◽

2004 ◽

Vol 10 (4) ◽

pp. S93

Author(s):

Amy K. Ferketich ◽

Philip F. Binkley

Keyword(s):

Heart Failure ◽

National Health ◽

Nhanes Iii ◽

Nutrition Examination Survey ◽

The Third ◽

Health And Nutrition

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Efficacy of Tolvaptan in Elderly Patients with Heart Failure and Preserved Ejection Fraction

Journal Of Cardiovascular Emergencies ◽

10.2478/jce-2019-0007 ◽

2019 ◽

Vol 5 (2) ◽

pp. 59-65

Author(s):

Yoriyasu Suzuki ◽

Akira Murata ◽

Satoshi Tsujimoto ◽

Yusuke Ochiumi ◽

Tatsuya Ito

Keyword(s):

Heart Failure ◽

Ejection Fraction ◽

Elderly Patients ◽

Hospital Stay ◽

Clinical Outcomes ◽

Rest Period ◽

Length Of Hospital Stay ◽

Bed Rest ◽

Preserved Ejection Fraction ◽

Patients With Heart Failure

Abstract Background: There is no known therapy with proven efficacy for improving clinical outcomes in elderly patients with heart failure (HF) and preserved ejection fraction (HFpEF). In this study, we aimed to evaluate the efficacy of tolvaptan (TLV) in elderly HFpEF patients. Methods: This retrospective observational study involved 100 consecutive elderly HFpEF patients hospitalized at the Nagoya Heart Center, Japan. Inclusion criteria were: (1) patients aged ≥75 years; (2) first hospitalization secondary to HF; (3) received medical therapy for HF, without invasive treatment; and (4) clinical follow-up for >6 months after discharge. The primary endpoint was rehospitalization due to worsening HF, and the secondary endpoint was worsening renal function (WRF) during hospitalization and at 6 months after discharge. Sixty background-matched HFpEF patients were divided into 2 groups: with TLV therapy (TLV (+), n = 29) and without TLV therapy (TLV (–), n = 31). In the TLV (+) group, TLV therapy was continued after discharge. Clinical outcomes of these patients were evaluated. Results: Bed rest period and length of hospital stay were significantly shorter in the TLV (+) group than in the TLV (−) group. The dose of loop diuretics, mean serum creatinine levels, and incidence of WRF development were significantly lower in the TLV (+) group. Incidence of rehospitalization was also significantly lower in the TLV (+) group (log-rank test; p = 0.018). The multivariate logistic regression analysis demonstrated that TLV therapy reduces the incidence of rehospitalization in elderly patients with HFpEF. Conclusions: TLV therapy reduced the bed rest period, length of hospital stay, and rate of rehospitalization without WRF in elderly HFpEF patients, suggesting that TLV could represent an effective therapy for this group of patients.

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