The durability, such as chloride ion permeability, freeze-thaw and sulfate attack resistance of ultra-high performance concrete (UHPC) having a large amount, ranged from 42% to 48% by weight of binder, of mineral admixtures including steel slag powder (SS), ultrafine fly ash (UFFA) and silica fume (SF) was studied and the microstructure of selected UHPC compositions was investigated by Mercury porosimetry in this paper. Moreover, the relationship between durability and microstructure of UHPC was analyzed. The mercury porosimetry studies demonstrated the very low porosity and a high proportion of the innocuous pores as well as the very small pore size in UHPCs, whose most probable pore diameter did not exceed 10 nm. This porous structure of UHPCs would definitely enable the material have excellent durability.