Distribution of bone mineral density with age and gender in the proximal tibia

Objective. Measure bone mineral density (BMD) in healthy Newfoundland adolescents and determine whether BMD is comparable in geographically diverse adolescent populations. Study design. Lumbar spine BMD was measured by dual-energy radiograph absorptiometry in 26 healthy adolescents between ages 8 and 20 years. The age and gender of these subjects were used to predict BMD from equations derived from normative BMD data in six geographically diverse populations. The actual BMD value obtained for each subject was then compared with each of the six predicted BMD values for that adolescent using the Wilcoxon signed-ranks test. Results. Actual lumbar spine BMD in Newfoundland adolescents was not significantly different from that predicted by age and gender if they were from California, Finland, France, North Carolina, and Switzerland. Only the prediction based on the Spanish population resulted in a 4% greater BMD than was actually measured in the Newfoundland adolescents. Conclusions. Lumbar spine BMD measurements for most healthy adolescent populations, as in adults, are comparable despite geographic diversity. Thus, generation of institution-specific normative BMD data may not be necessary for most adolescent populations.

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The relationships between bone mineral density in the spine, hip, distal femur and proximal tibia and medial minimum joint space width in the knees of healthy females

Osteoarthritis and Cartilage ◽

10.1016/j.joca.2005.06.010 ◽

2005 ◽

Vol 13 (10) ◽

pp. 872-878 ◽

Cited By ~ 12

Author(s):

K.A. Beattie ◽

P. Boulos ◽

J. Duryea ◽

J. O'Neill ◽

M. Pui ◽

...

Keyword(s):

Bone Mineral Density ◽

Bone Mineral ◽

Distal Femur ◽

Proximal Tibia ◽

Joint Space Width ◽

Joint Space ◽

Mineral Density ◽

Minimum Joint Space Width ◽

Space Width ◽

Healthy Females

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Protective effect ofGlycyrrhiza glabraroots extract on bone mineral density of ovariectomized rats

BioMedicine ◽

10.1051/bmdcn/2019090208 ◽

2019 ◽

Vol 9 (2) ◽

pp. 8 ◽

Cited By ~ 2

Author(s):

Dimitrios Galanis ◽

Konstantinos Soultanis ◽

Pavlos Lelovas ◽

Alexandros Zervas ◽

Panagiotis Papadopoulos ◽

...

Keyword(s):

Bone Mineral Density ◽

Bone Density ◽

Protective Effect ◽

Bone Mineral ◽

Proximal Tibia ◽

Glycyrrhiza Glabra ◽

Ovariectomized Rats ◽

Mineral Density ◽

Three Point Bending ◽

Significant Difference

Objective: The aim of this study was to evaluate the potential effect of the methanolic extract of plantGlycyrrhiza glabraroots on bone mineral density and femoral bone strength of ovariectomized rats.Methods: Thirty 10-month-old Wistar rats were randomly separated into three groups of ten, Control, Ovariectomy and Ovariectomy-plus-Glycyrrhiza in their drinking water. Total and proximal tibial bone mineral density was measured in all groups before ovariectomy (baseline) and after 3 and 6 months post ovariectomy. Three-point-bending of the femurs and uterine weight and histology were examined at the end of the study.Results: No significant difference was noted in bone density percentage change of total tibia from baseline to 3 months between Control and Ovariectomy-plus-Glycyrrhiza groups (+5.31% ± 4.75 and +3.30% ± 6.31 respectively,P = non significant), and of proximal tibia accordingly (+5.58% ± 6.92 and +2.61% ± 13.62,P = non significant) demonstrating a strong osteoprotective effect. There was notable difference in percentage change of total tibia from baseline to 6 months between groups Ovariectomy and Ovariectomy-plus-Glycyrrhiza (−13.03% ± 5.11 and −0.84% ± 7.63 respectively,P < 0.005), and of proximal tibia accordingly (−27.9% ± 3.69 and −0.81% ± 14.85 respectively,P < 0.001), confirming the protective effect ofGlycyrrhiza glabraextract in preserving bone density of the Ovariectomy-plus-Glycyrrhiza group. Three-point-bending did not reveal any statistically significant difference between Ovariectomy and Ovariectomy-plus-Glycyrrhiza groups. Uterine weights of the Ovariectomy-plus-Glycyrrhiza group ranged between the other two groups with no statistically significant difference to each.Conclusions:Glycyrrhiza glabraroot extract notably protected tibial bone mineral density loss in Ovariectomy-plus-Glycyrrhiza rats in comparison with ovariectomized rats, but did not improve biomechanical strength.

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Bone Mineral Density of Cervical Spine Vertebrae Using Quantitative Computed Tomography

Advances in Bioengineering ◽

10.1115/imece2004-59726 ◽

2004 ◽

Author(s):

Narayan Yoganandan ◽

Frank A. Pintar ◽

Recai Aktay ◽

Glenn Paskoff ◽

Barry S. Shender

Keyword(s):

Computed Tomography ◽

Bone Mineral Density ◽

Cervical Spine ◽

Bone Mineral ◽

Cervical Vertebrae ◽

Quantitative Computed Tomography ◽

Mineral Density ◽

Healthy Human ◽

Computed Tomography Scanning ◽

And Gender

While numerous studies exist quantifying the bone mineral content of the human lumber vertebrae, such information is not available for the cervical spine. This study determined the bone mineral densities of cervical vertebrae. Adult healthy human volunteers, ages ranging from 18 to 40 years, underwent quantitative computed tomography scanning of the neck. BMD data were divided according to subject weight (above and below 50th percentile, termed low and heavy mass) and gender. Low-mass subjects did not consistently have higher bone mineral density at all levels of the cervical column. Bone mineral were higher (259 ± 6 mg/cc) for females than males (247 ± 8 mg/cc); for the entire ensemble the mean density was 253 ± 9 mg/cc. Altered strength of cervical vertebrae coupled with the increased mobility of the disc at the inferior levels of the neck may explain regional biomechanical differences and subsequent physiologic effects secondary to aging. This study quantifies BMD of the human neck vertebrae and offers explanations to the biomechanical behaviors of the human cervical spine.

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