scholarly journals R-wave amplitude changes with posture and physical activity over time in an insertable cardiac monitor

Author(s):  
Matthew Swale ◽  
Sinny Delacroix ◽  
Glenn Young ◽  
Vincent Paul ◽  
Luke McSpadden ◽  
...  
2020 ◽  
Vol 29 ◽  
pp. S255-S256
Author(s):  
M. Swale ◽  
S. Delacroix ◽  
G. Young ◽  
V. Paul ◽  
L. McSpadden ◽  
...  

Heart Rhythm ◽  
2021 ◽  
Vol 18 (8) ◽  
pp. S189
Author(s):  
Bradley M. Pitman ◽  
Rachel Tarone ◽  
Esther Jones ◽  
Kadhim Kadhim ◽  
Ricardo Mishima ◽  
...  

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
B.M Pitman ◽  
R Tarone ◽  
E Jones ◽  
K Kadhim ◽  
D Linz ◽  
...  

Abstract Background P-wave visibility is useful for diagnosis of atrial arrhythmias via insertable cardiac monitors (ICM). Purpose To compare the sensing capability of ICM with different vector length: Medtronic REVEAL LINQ (45mm) vs. Biotronik Biomonitor BMIII (75mm). Methods We accessed de-identified remote monitoring transmissions from n=40 patients with BMIII from Biotronik for comparison with n=80 gender- and body mass index (BMI)-matched patients with REVEAL LINQ. Digital measurement of calibrated ICM electrograms was performed using DigitizeIt© (V2.3.3, Germany) of 5 consecutive P-QRS complexes by 3 investigators independently. P-wave amplitude was measured from baseline to peak and R-wave amplitude was measured from peak-to-peak. Further, we evaluated the impact of BMI on P-wave visibility. Results Patients in both groups are well matched for gender and BMI (53% male, mean BMI 26.7 kg/m2; both p=NS). P-wave and R-wave amplitude were 89% & 20% larger in the BMIII vs. LINQ (0.072±0.039 vs. 0.038±0.022mV, p=0.0001; & 0.83±0.42 vs. 0.69±0.45mV, p=0.095 respectively; Figure). Consequently, the P/R-wave ratio was 44% greater for the BMIII (p=0.002). Multivariate regression analysis showed that increasing BMI, female gender and LINQ were independently associated with lower P-wave amplitude (all P<0.001). Inter-operator reproducibility of P-wave measures was very good (ICC 0.91, P<0.001). Conclusion The longer ICM sensing vector of BMIII yielded considerable larger P-wave amplitude than LINQ, that was not impacted by increasing BMI. Better P-wave visibility may improve clinical decision-making after device-detected arrhythmias while further studies are needed to determine its impact on clinical outcomes. P-wave visibility comparison of ICMs Funding Acknowledgement Type of funding source: None


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Liane D. Heale ◽  
Kristin M. Houghton ◽  
Elham Rezaei ◽  
Adam D. G. Baxter-Jones ◽  
Susan M. Tupper ◽  
...  

Abstract Background Physical activity (PA) patterns in children with juvenile idiopathic arthritis (JIA) over time are not well described. The aim of this study was to describe associations of physical activity (PA) with disease activity, function, pain, and psychosocial stress in the 2 years following diagnosis in an inception cohort of children with juvenile idiopathic arthritis (JIA). Methods In 82 children with newly diagnosed JIA, PA levels, prospectively determined at enrollment, 12 and 24 months using the Physical Activity Questionnaire for Children (PAQ-C) and Adolescents (PAQ-A) raw scores, were evaluated in relation to disease activity as reflected by arthritis activity (Juvenile Arthritis Disease Activity Score (JADAS-71)), function, pain, and psychosocial stresses using a linear mixed model approach. Results in the JIA cohort were compared to normative Pediatric Bone Mineral Accrual Study data derived from healthy children using z-scores. Results At enrollment, PA z-score levels of study participants were lower than those in the normative population (median z-score − 0.356; p = 0.005). At enrollment, PA raw scores were negatively associated with the psychosocial domain of the Juvenile Arthritis Quality of Life Questionnaire (r = − 0.251; p = 0.023). There was a significant decline in PAQ-C/A raw scores from baseline (median and IQR: 2.6, 1.4–3.1) to 24 months (median and IQR: 2.1, 1.4–2.7; p = 0.003). The linear mixed-effect model showed that PAQ-C/A raw scores in children with JIA decreased as age, disease duration, and ESR increased. The PAQ-C/A raw scores of the participants was also negatively influenced by an increase in disease activity as measured by the JADAS-71 (p <  0.001). Conclusion Canadian children with newly diagnosed JIA have lower PA levels than healthy children. The decline in PA levels over time was associated with disease activity and higher disease-specific psychosocial stress.


2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Eliane S. Engels ◽  
Michael Mutz ◽  
Yolanda Demetriou ◽  
Anne K. Reimers

Abstract Background Latest studies indicated that the general mental health level is low during the pandemic. Probably, this deterioration of the mental health situation is partly due to declines in physical activity. The aim of this study was to investigate differences in and the association between affective wellbeing and levels of different domains of physical activity at three time points before and during the pandemic. Method We used a nationwide online panel with a trend data design encompassing a total sample of N = 3517, representing the German population (> 14 years). Four different activity domains (sport and exercise, light outdoor activity, housework/gardening, active travel) and affective wellbeing (positive and negative affect) were assessed at three time points before and during the Covid-19 pandemic (October 2019, March 2020, October 2020). Results Multivariate analyses of variance (MANOVA) indicate differences regarding affective wellbeing over the three time points with the lowest values at the second time point. Levels of activity in the four domains differed significantly over time with the strongest decrease for sport and exercise from the first to the second time point. Partial correlations indicated that the relationships between sport and exercise and positive affect were most consistent over time. Conclusions Overall, our findings suggest that physical activity plays a particularly important role in the pandemic period as a protective factor against poor mental health. Especially sports and exercise seem to be supportive and should be encouraged, e.g. by providing additional support in finding adequate outdoor, home-based or digital substitutes.


2021 ◽  
pp. bjsports-2020-103140
Author(s):  
Rodney K Dishman ◽  
Cillian P McDowell ◽  
Matthew Payton Herring

ObjectiveTo explore whether physical activity is inversely associated with the onset of depression, we quantified the cumulative association of customary physical activity with incident depression and with an increase in subclinical depressive symptoms over time as reported from prospective observational studies.DesignSystematic review and meta-analysis.Data sourcesMEDLINE, PsycINFO, PsycARTICLES and CINAHL Complete databases, supplemented by Google Scholar.Eligibility criteriaProspective cohort studies in adults, published prior to January 2020, reporting associations between physical activity and depression.Study appraisal and synthesisMultilevel random-effects meta-analysis was performed adjusting for study and cohort or region. Mixed-model meta-regression of putative modifiers.ResultsSearches yielded 111 reports including over 3 million adults sampled from 11 nations in five continents. Odds of incident cases of depression or an increase in subclinical depressive symptoms were reduced after exposure to physical activity (OR, 95% CI) in crude (0.69, 0.63 to 0.75; I2=93.7) and adjusted (0.79, 0.75 to 0.82; I2=87.6) analyses. Results were materially the same for incident depression and subclinical symptoms. Odds were lower after moderate or vigorous physical activity that met public health guidelines than after light physical activity. These odds were also lower when exposure to physical activity increased over time during a study period compared with the odds when physical activity was captured as a single baseline measure of exposure.ConclusionCustomary and increasing levels of moderate-to-vigorous physical activity in observational studies are inversely associated with incident depression and the onset of subclinical depressive symptoms among adults regardless of global region, gender, age or follow-up period.


Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 634 ◽  
Author(s):  
Andrea Greco ◽  
Agostino Brugnera ◽  
Roberta Adorni ◽  
Marco D’Addario ◽  
Francesco Fattirolli ◽  
...  

Cardiovascular disease is one of the most common causes of hospitalization and is associated with high morbidity and mortality rates. Among the most important modifiable and well-known risk factors are an unhealthy diet and sedentary lifestyle. Nevertheless, adherence to healthy lifestyle regimes is poor. The present study examined longitudinal trajectories (pre-event, 6-, 12-, 24-, 36-, and 60-month follow-ups) of protein intake (fish, legumes, red/processed meat) and physical activity in 275 newly-diagnosed patients with acute coronary syndrome. Hierarchical Generalized Linear Models were performed, controlling for demographic and clinical variables, the season in which each assessment was made, and the presence of anxiety and depressive symptoms. Significant changes in protein intake and physical activity were found from pre-event to the six-month follow-up, suggesting the adoption of healthier behaviors. However, soon after the six-month follow-up, patients experienced significant declines in their healthy behaviors. Both physical activity and red/processed meat intake were modulated by the season in which the assessments took place and by anxiety symptoms over time. The negative long-term trajectory of healthy behaviors suggests that tailored interventions are needed that sustain patients’ capabilities to self-regulate their behaviors over time and consider patient preference in function of season.


Heart Rhythm ◽  
2021 ◽  
Vol 18 (8) ◽  
pp. S121-S122
Author(s):  
Yuanzhen Liu ◽  
Xusheng Zhang ◽  
Paul J. DeGroot ◽  
Christopher Wiggenhorn ◽  
Samuel Liang ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yoshihiro Osawa ◽  
Kaho Nomura ◽  
Yoshifumi Kimira ◽  
Seiji Kushibe ◽  
Ken-ichi Takeyama ◽  
...  

AbstractActive collagen oligopeptides (ACOP) are bioactive collagen-derived peptides detected by a recently-established ELISA. To facilitate studies of the function and metabolism of these products, this study aims to determine which of these peptides is recognized by a novel anti-ACOP antibody used in this ELISA. We then investigate the effect of collagen peptide (CP) ingestion and exercise on urinary ACOP concentrations in a cohort of university student athletes using colorimetric, LC–MS/MS, and ELISA. We observed that the antibody showed strong cross-reactivity to Pro-Hyp and Gly-Pro-Hyp and weak cross-reactivity to commercial CP. CP ingestion increased the urinary level of ACOP over time, which correlated highly with urinary levels of peptide forms of Hyp and Pro-Hyp. Physical activity significantly decreased the urinary ACOP level. This study demonstrates changes in urinary ACOP following oral CP intake and physical activity using ELISA with the novel anti-ACOP antibody. Thus, ACOP may be useful as a new biomarker for collagen metabolism.


Sign in / Sign up

Export Citation Format

Share Document