Sleep disturbances and low psychological well-being are associated with an increased risk of autoimmune diabetes in adults. Results from the Nord-Trøndelag Health Study

2012 ◽  
Vol 98 (2) ◽  
pp. 302-311 ◽  
Author(s):  
Lisa Olsson ◽  
Anders Ahlbom ◽  
Valdemar Grill ◽  
Kristian Midthjell ◽  
Sofia Carlsson
Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Amit J Shah ◽  
Robert Carney ◽  
Elsayed Z Soliman ◽  
Viola Vaccarino

Background: Abnormal frontal T-axis is an independent predictor of mortality, and may be influenced by increased sympathetic tone and cardiovascular disease risk factors. Factors related to poor psychological health, such as depression, are associated with increased risk of CVD morbidity, although the mechanisms are not clear. We tested the hypothesis that: 1) reduced psychological wellness is associated with abnormal T-axis and 2) this association may help to explain the excess risk of CVD morbidity and mortality related to poor psychological health. Methods: We studied 4485 community-based adults aged 25–65 years without a history of CVD from NHANES I (1971–75) who were monitored for CVD hospitalization and death until 1993. Those with ECG evidence of previous MI, left ventricular hypertrophy, and major ventricular conduction defects (QRS interval ≥ 120 ms) were excluded. Frontal T-axis was obtained through 12-lead ECG, and a deviation of ≥ 30° from normal (45°) was considered abnormal. Psychological well-being was measured with the General Well-Being Scale (GWB). Results: The mean ± SD age was 43.1 ± 11.5 years and 55% were women. The mean ± SD GWB score was 80.5 ± 17.3, the median frontal T-axis was 51°, and 13% had an abnormal T-axis. In cross-sectional analysis adjusting for age, sex, and race, a 1-SD decrease in GWB was associated with an OR of 1.12 for abnormal T-axis (p=0.01). This effect was unchanged after adjusting for systolic blood pressure, smoking, diabetes, total cholesterol, and BMI. Abnormal T-axis was associated with CVD hospitalization/death (adjusted HR 1.29, p=0.01), as was GWB (adjusted HR 1.104 per 1-SD decrease, p=0.01). When both factors were included in the model, the HR of GWB decreased by 8% to 1.096 (p=0.02). Conclusion: Abnormal frontal T-axis is modestly but significantly associated with reduced psychological wellness. Although this association may help understand neurocardiac relationships, it does not substantially explain morbidity and mortality associated with reduced psychological wellness.


2013 ◽  
Vol 2013 ◽  
pp. 1-14 ◽  
Author(s):  
T. Feicht ◽  
M. Wittmann ◽  
G. Jose ◽  
A. Mock ◽  
E. von Hirschhausen ◽  
...  

Background. As distress in society increases, including work environments, individual capacities to compete with stress have to be strengthened.Objective. We examined the impact of a web-based happiness training on psychological and physiological parameters, by self-report and objective means, in an occupational health setting.Methods. Randomized controlled trial with 147 employees. Participants were divided into intervention (happiness training) and control groups (waiting list). The intervention consisted of a seven-week online training. Questionnaires were administered before, after, and four weeks after training. The following scales were included: VAS (happiness and satisfaction), WHO-5 Well-being Index, Stress Warning Signals, Freiburg Mindfulness Inventory, Recovery Experience Questionnaire, and Flourishing Scale. Subgroup samples for saliva cortisol and alpha-amylase determinations were taken, indicating stress, and Attention Network Testing for effects on attention regulation.Results. Happiness (P=0.000;d=0.93), satisfaction (P=0.000;d=1.17), and quality of life (P=0.000;d=1.06) improved; perceived stress was reduced (P=0.003;d=0.64); mindfulness (P=0.006;d=0.62), flourishing (P=0.002;d=0.63), and recovery experience (P=0.030;d=0.42) also increased significantly. No significant differences in the Attention Network Tests and saliva results occurred (intergroup), except for one saliva value.Conclusions. The web-based training can be a useful tool for stabilizing health/psychological well-being and work/life balance.


2021 ◽  
Vol 36 (6) ◽  
pp. 1061-1061
Author(s):  
Ni Sun-Suslow ◽  
C Wei-Ming Watson ◽  
Jennifer Iudicello ◽  
Robert K Heaton ◽  
Erin E Morgan

Abstract Objective People with HIV (PWH) are more likely to experience problematic emotions and are at increased risk for frailty. In the general population, frailty is broadly associated with worse social–emotional functioning. However, the extent of this dysfunction has largely been isolated to depression and these relationships have yet to be examined among PWH. Thus, this study examined associations between frailty and summary factor scores developed from the National Institutes of Health Toolbox Emotion Battery (NIH-TB-EB) among PWH. Method Participants were 320 PWH (mean age = 52.3, SD = 12.7). Three previously validated composite scores from the NIH-TB-EB were used to assess social–emotional functioning: negative affect, social satisfaction, and psychological well-being. Using the Fried Phenotype, the sample was dichotomized into non-frail (n = 155) and prefrail/frail (n = 165) groups. Multiple regression was used to examine the association between frailty and social–emotional functioning. Covariates included age, estimated duration of HIV infection, antiretroviral therapy (ART) status, and antidepressant medication count. Results Being prefrail/frail was associated with increased negative affect (B = 0.26, p < 0.001), decreased social satisfaction (B = -0.18, p = 0.002), and decreased psychological well-being (B = -0.25, p < 0.001). Increased age was associated with decreased negative affect (B = -0.17, p = 0.002), and was unrelated to social satisfaction and psychological well-being. Estimated duration of infection, ART status, and antidepressant use were not associated with social–emotional functioning. Conclusions Pre-frail/frail PWH have worse social–emotional functioning, above and beyond age, duration of HIV disease, ART status, and antidepressant use. This suggests both frailty and poor social–emotional functioning may be important targets to screen and treat in order to improve prognosis and quality of life for PWH.


1989 ◽  
Vol 10 (1) ◽  
pp. 72-85 ◽  
Author(s):  
WILLIAM J. DOHERTY ◽  
SUSAN SU ◽  
RICHARD NEEDLE

This study offers prospective data on the psychological well-being of men and women before and after a marital separation, in comparison with a control group who remained married during the same period. Data were gathered as part of the Minnesota Family Health Study on a primarily middle-class White sample. Primary variables were current psychological well-being, self-esteem, mastery, substance use, and family income. Findings were quite different for men and women. Prior to separation, men in the disrupted group had lower psychological well-being scores than the continuously married group had, but showed no declines in any of the measures in the follow-up period. Separated women scored lower than did women from continuing marriages on psychological well-being prior to the separation, and they declined further afterwards. Separated women also increased their use of alcohol and other substances, and experienced a decline in family income. Findings are discussed in terms of the social causation hypothesis and the social selection hypothesis for understanding the relationship between divorce and mental health in adults.


Author(s):  
Kate A Leger ◽  
Tessa R Blevins ◽  
Leslie J Crofford ◽  
Suzanne C Segerstrom

Abstract Background Disturbed sleep is prevalent in older adulthood and particularly among women. Greater psychological well-being (PWB) is associated with better sleep, but intraindividual variability in PWB has not been examined. Purpose The current study examined whether mean levels and variability in PWB were associated with sleep disturbances in midlife and older women. Methods Participants (N = 189) completed up to seven daily diaries and an end of the week assessment every 3 months for nine waves. Participants answered questions about their nightly sleep disturbances and reported their PWB using Ryff’s six dimensions of PWB. Results Regression models indicated that greater variability in one aspect of PWB, positive relations with others, was related to greater sleep disturbance even after adjusting for mean levels of well-being. Greater variability in environmental mastery, purpose in life, and self-acceptance were also associated with sleep disturbance, but these associations were no longer significant after adjusting for mean levels of well-being. Conclusions Results suggest that fluctuations in positive relations with others are related to sleep in adult women above and beyond mean levels of well-being. Results highlight the importance of considering variability in addition to mean levels of PWB.


2005 ◽  
Vol 35 (3) ◽  
pp. 499-528 ◽  
Author(s):  
Gunnar Aronsson ◽  
Margareta Dallner ◽  
Tomas Lindh ◽  
Sara Göransson

The aim of the study was to investigate the financial circumstances of a group of temporary employees and whether personal financial strain is related to an increased risk of ill-health. The study group consisted of 778 on-call employees. The response rate to a mailed questionnaire was 56 percent. Twenty percent of respondents stated that they had experienced economic difficulties of some kind. More than 50 percent regarded their form of employment as an impediment to obtaining a loan, and approximately 40 percent regarded it as a barrier to acquiring a housing contract. The study group is strongly polarized with regard to personal financial matters. There is a clear connection between poverty and health. Individuals who were both worried about their personal finances and objectively poor had far lower levels of psychological well-being (as measured by GHQ-12), more stomach, back, and neck complaints, more headaches, and greater tiredness and listlessness. Sleep disturbances acted as a mediating variable between financial pressure and stomach problems.


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