Erratum to “Relationships between left atrial pericardial fat and permanent atrial fibrillation: Results of a case-control study” [Diagn. Interv. Imaging. 97 (2016) 307–13]

Abstract Background: Atrial fibrillation (AF) is a common arrhythmia that induces disability or death; however, the underlying pathogenesis is yet unclear. This study aimed to investigate the expression of matrix metalloproteinase-9 (MMP-9) in rheumatic valvular heart disease (RVHD) and its value in predicting AF.Methods: In this single-center, prospective case-control study, 30 patients who received valve replacement for the treatment of RVHD in the Cardiac and Major Vascular Department, Yue Bei People’s Hospital between August 2012 and January 2015 were included in this study. The patients were categorized equally into two groups according to the electrocardiogram characteristics: sinus rhythm (SR) group and chronic atrial fibrillation (AF) group. In patients hospitalized for RVHD, the fasting serum was collected on the following day in the morning, and the tissues of right auricle were collected during the operation. Hematoxylin and eosin staining and Masson staining were performed to assess the pathological structures of myocardial tissues and changes in collagen fibers. Enzyme-linked immunosorbent assay was used to measure the level of MMP-9 in serum, and the distribution of the protein in myocardial tissues was assessed by immunohistochemistry. Echocardiography was performed before the surgery to measure the left atrial diameter and ejection fraction.Results: The MMP-9 expression was significantly higher in the AF group than the SR group (4.2281 ± 0.9165 ng/mg vs. 2.7613 ± 1.2166 ng/mg, p < 0.05). The MMP-9 levels were positively associated with left atrial diameter (LAD) (p < 0.01) and collagen volume fraction (CVF) (p < 0.05).Conclusions: MMP-9 expression is elevated in AF patients and could be one of the major factors involved in the remodeling of atrial structures in AF. MMP-9 influences the metabolism of collagen and promotes the fibrosis of the myocardium, participates in cardiac structural remodeling, and plays a role in the onset and maintenance of AF.

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Left Atrial Mechanical Dispersion Assessed by Strain Echocardiography as an Independent Predictor of New-Onset Atrial Fibrillation: A Case-Control Study

Journal of the American Society of Echocardiography ◽

10.1016/j.echo.2019.06.002 ◽

2019 ◽

Vol 32 (10) ◽

pp. 1268-1276.e3 ◽

Cited By ~ 4

Author(s):

Hiroshi Kawakami ◽

Satish Ramkumar ◽

Mark Nolan ◽

Leah Wright ◽

Hong Yang ◽

...

Keyword(s):

Atrial Fibrillation ◽

Left Atrial ◽

Case Control Study ◽

Independent Predictor ◽

Case Control ◽

Mechanical Dispersion ◽

Onset Atrial Fibrillation ◽

Control Study ◽

Strain Echocardiography ◽

New Onset

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Faculty Opinions recommendation of Non-steroidal anti-inflammatory drug use and risk of atrial fibrillation or flutter: population based case-control study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13274958.14631057 ◽

2011 ◽

Author(s):

Juan Tamargo

Keyword(s):

Atrial Fibrillation ◽

Drug Use ◽

Case Control Study ◽

Population Based ◽

Case Control ◽

Inflammatory Drug ◽

Anti Inflammatory ◽

Control Study

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AB0360 Left atrial dilation is increased in patients with rheumatoid arthritis: a case-control study

10.1136/annrheumdis-2018-eular.7098 ◽

2018 ◽

Cited By ~ 1

Author(s):

D.A. Galarza-Delgado ◽

J.R. Azpiri-López ◽

I.J. Colunga-Pedraza ◽

J.A. Dávila-Jiménez ◽

E.E. Abundis-Márquez ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Left Atrial ◽

Case Control Study ◽

Case Control ◽

Control Study

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Association between anxiety symptoms and atrial fibrillation in a community cohort of Chinese older adults: a case-control study

BMC Cardiovascular Disorders ◽

10.1186/s12872-021-02278-x ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Zhu-Xia Shen ◽

Yu-Min Sun ◽

Hui-Hui Gu ◽

Yan Zhang ◽

Zhi-Wen Shen ◽

...

Keyword(s):

Atrial Fibrillation ◽

Older Adults ◽

Heart Disease ◽

Odds Ratio ◽

Case Control Study ◽

Case Control ◽

Anxiety Symptoms ◽

Control Group ◽

Community Based ◽

Control Study

Abstract Background The association between anxiety and atrial fibrillation (AF) remains unclear. Moreover, this association has rarely been studied in Chinese individuals aged 60 years or older. This study investigated the association between anxiety and AF in a community-based case-control study of older adult residents in urban China. Methods The cases and controls were from a community-based study conducted in the Jingansi community in Shanghai, China, between January 2010 and December 2012. A total of 3622 residents aged 60 years or older without severe vision, hearing, or speaking impairments were eligible to participate in the physical examinations and questionnaire survey. AF was assessed based on a previous physician’s diagnosis, electrocardiogram, ambulatory electrocardiogram, or echocardiogram. Anxiety was evaluated using the Zung Self-Rating Anxiety Scale (ZSAS). Using the AF group as a reference, the control group consisted of randomly selected age- and sex-matched individuals in a 1:5 ratio (case:control = 1:5). The association between anxiety and AF in the AF group and the multifactor-matched control group was explored using logistic regression. Results In the AF and control groups, after adjusting for a history of coronary heart disease, valvular heart disease, hypertension, stroke, hyperlipidemia, and diabetes, as well as depression score, ZSAS scores (odds ratio 1.07; 95% confidence interval 1.02–1.12; p = 0.003), and anxiety symptoms (odds ratio 3.94; 95% confidence interval 1.06–14.70; p = 0.041) were associated with AF. Conclusions Anxiety symptoms were associated with AF in a Chinese older population. This suggests that older adults who have anxiety symptoms may need psychological intervention or treatment in daily life and care.

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Does Parkinson's Disease Increase the Risk of Atrial Fibrillation? Insights From Electrocardiogram and Risk Scores From a Case-Control Study

Frontiers in Neurology ◽

10.3389/fneur.2021.633900 ◽

2021 ◽

Vol 12 ◽

Author(s):

Mariana Alves ◽

Ana Mafalda Abrantes ◽

Gonçalo Portugal ◽

M. Manuela Cruz ◽

Sofia Reimão ◽

...

Keyword(s):

Atrial Fibrillation ◽

Case Control Study ◽

Case Control ◽

P Wave ◽

Risk Scores ◽

Wave Duration ◽

P Wave Duration ◽

Increased Risk ◽

The Mean ◽

Control Study

Background: Previous studies suggested that Parkinson's Disease (PD) patients could have an increased risk of atrial fibrillation. However, data supporting this association is not robust. We aimed to compare the potential risk of atrial fibrillation associated with PD in an age and gender matched case-control study, comparing the p-wave indexes from electrocardiograms and clinical risk scores among groups.Methods: A cross-sectional case-control study was performed. All subjects included in the analysis were clinically evaluated and subjected to a 12-lead electrocardiogram. Two blinded independent raters measured the p-wave duration. Subjects were classified as having normal P-wave duration (<120 ms), partial IAB (P-wave duration ≥ 120 ms, positive in inferior leads), and advanced IAB (p-wave duration ≥ 120 ms with biphasic morphology in inferior leads). Atrial fibrillation risk scores (CHARGE-AF, HATCH, and HAVOC) were calculated.Results: From 194 potential participants, three were excluded from the control group due to a previous diagnosis of atrial fibrillation. Comparing the PD patients (n = 97) with controls (n = 95), there were no statistically significant differences regarding the mean p-wave duration (121 ms vs. 122 ms, p = 0.64) and proportion of advanced interatrial block (OR = 1.4, 95%CI = 0.37–5.80, p = 0.58). All patients had a low or medium risk of developing atrial fibrillation based on the clinical scores. There were no differences between the PD patients and controls regarding the mean values of CHARGE-AF, HATCH, and HAVOC.Conclusions: Our results do not support the hypothesis that PD patients have an increased risk of atrial fibrillation based on the p-wave predictors and atrial fibrillation clinical scores.

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