438. Outcome of radical cholecystectomy for gallbladder cancer patients in a tertiary care oncology centre in Northern India

2016 ◽  
Vol 42 (9) ◽  
pp. S165-S166
Author(s):  
A. Mishra ◽  
S. Bhoriwal ◽  
M. Sultania ◽  
S. Deo ◽  
N. Shukla ◽  
...  
2020 ◽  
pp. 1-9
Author(s):  
S. Suhani ◽  
Mufaddal Kazi ◽  
Rajinder Parshad ◽  
Vathulru Seenu ◽  
Eshan Verma ◽  
...  

HPB ◽  
2018 ◽  
Vol 20 ◽  
pp. S711
Author(s):  
A. Pandey ◽  
K. Noman ◽  
S. Masood ◽  
S. Chauhan ◽  
A. Gupta ◽  
...  

2020 ◽  
Vol 5 (S1) ◽  
pp. 51-57
Author(s):  
Dharmendra Singh ◽  
Pritanjali Singh ◽  
Avik Mandal ◽  
Amrita Rakesh ◽  
Manika Verma

Introduction: The novel coronavirus disease 2019 (COVID-19), is caused by the severe acute respiratory syndrome cronavirus 2 (SARS-CoV2). The management of cancer patients is very challenging during the COVID-19 pandemic. Cancer itself as well as anticancer treatment leads to compromised immunity of patients with increased risk of infection. This is turn leads to increased hospital visits. It forms a vicious cycle that increases the risk of COVID-19 susceptibility to cancer patients. Patients on anticancer treatment alongwith COVID-19 infection have higher risk of morbidity and mortality. Aim: To compare the epidemiological characteristics and management decisions in gallbladder cancer patients during COVID-19 pandemic. Methods: This retrospective study was conducted at All India Institute of Medical Sciences (AIIMS), Patna. Patients were divided into two group pre-COVID (patients attending radiotherapy department from December 2019 to February 2020) and established-COVID group patients (patients attending radiotherapy department from March 2020 to May 2020) with histopathological confirmed diagnosis of gallbladder cancer. Results: Histopathological confirmed cases of gallbladder cancer (n=85) were analyzed, 56 patients from pre-COVID timeline and 29 patients from established-COVID timeline were selected. During the pre-COVID timeline, 55.4% of the patients directly visited the radiotherapy department while, 24.1% patients directly attended the radiotherapy department during the established-COVID time. This reduction of number of patients at radiotherapy department was statistically significant (p = 0.006). There was statistically significant reduction (p = 0.014) in number of patients attending from rural areas during established-COVID time. Chemotherapy regimen used during pre-COVID and establishedCOVID timeline was significantly (p < 0.001) different. Conclusion: Cancer patient management during COVID-19 pandemic is an important issue. Chemotherapy increases the risk of COVID-19 infection by reducing the immunity. Single agent oral capecitabine is a good option for patients of gallbladder cancer in the adjuvant or palliative settings with less toxicity and requiring less hospital visits compared to intravenous chemotherapy. 


2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 19675-19675
Author(s):  
H. Singh ◽  
S. Chawla ◽  
A. J. Joshi ◽  
D. Marwaha ◽  
R. R. Saggar ◽  
...  

19675 Background: Psoas abscess is regarded as a rare disease in medical literature, more so as primary presentation of malignancy or its recurrence. We describe a series of 10 cancer patients who presented with psoas abscess seen in a 18 month period at a large tertiary care cancer hospital in northern India. They were subsequently diagnosed as having malignancy or recurrence of a past malignancy. Methods: A retrospective study of cancer patients who presented with psoas abscess was undertaken. We reviewed clinical data from patients who presented in the period from April 2005 to December 2006 at the Patel Cancer & Superspeciality hospital, Jalandhar, India. Results: In this period 10 cases of cancer met the diagnosis of psoas abscess at presentation. The average age was 51 years (range 20 to 85) with a male female ratio of 4:1. In 7 patients psoas abscess was the presentation at initial diagnosis while in 3 patients it was the presentation of recurrence/relapse. None of the patients had any predisposing conditions like IV drug use, diabetes mellitus, hematoma or HIV positivity.. Majority (7/10) of primary tumors were genito- urinary cancers (Renal - 2, Ureter - 1, Cervix - 1, Prostate - 1, Dysgerminoma - 1, Penis-1) while 3 were of unknown origin. Squamous cell carcinoma was the commonest histology (4/10), followed by metastatic adenocarcinoma (3/10). Majority of the abscess were left sided (7/10) corresponding to the side of primary lesion. Under lying destruction of iliac bone with metastasis was found in only 2 patients. Most of the patients (9/10) responded poorly to treatment ie chemotherapy and radiotherapy, all of them dying of disease progression within a year. Conclusions: Psoas abscess can be a rare presentation of intra abdominal malignancy. Pre disposing factors may not necessarily be present. Genito-urinary malignancies should be kept in the differential diagnosis of unexplained psoas abscesses. Development of psoas abscess does not always signify metastatic disease but portends a poor prognosis to treatment. No significant financial relationships to disclose.


2021 ◽  
Vol 27 (45) ◽  
pp. 7813-7830
Author(s):  
Shaifali Goel ◽  
Abhishek Aggarwal ◽  
Assif Iqbal ◽  
Vineet Talwar ◽  
Swarupa Mitra ◽  
...  

2017 ◽  
Vol 06 (04) ◽  
pp. 171-175 ◽  
Author(s):  
Randeep Singh ◽  
Nitesh Rohtagi

Abstract Aims: The primary objective of this study was to estimate the clinicopathological and molecular profile of lung cancer patients along with the evaluation of their clinical characteristics at a tertiary care hospital in Northern India. Subjects and Methods: A total of 421 patients with lung cancer histology who were treated at Max Super Speciality Hospitals were included in the study. The study protocol conforms to the ethical guidelines of the 1975 Declaration of Helsinki and permission was obtained from the Ethics Committee before the start of the study. Clinical characteristics and molecular profiling data were collected from the patient's medical records. Results: There were 330 (78.4%) men and 91 (21.6%) women with a median age of 62 years (range: 30–93 years). Of the 421 patients, 388 (92.2%) patients had the nonsmall cell lung cancer (NSCLC) histology whereas 33 (7.8%) patients were of SCLC histology. Histology and gender had a significant association with NSCLC and SCLC (P < 0.05). Epidermal growth factor receptor (EGFR) and echinoderm microtubule-associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene testing was done in 120 and 93 patients, respectively. Of the 120 patients, 24 (20%) cases were positive for EGFR mutations whereas EML4-ALK fusion gene was present in 8 (8.6%) out of 93 patients. Conclusions: Our study confirms the importance of molecular testing in the NSCLC patient subgroup with an aim to identify the exact molecular targets that can benefit from the newer generation of targeted therapies.


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