Psychiatric symptoms and use of psychotropic medication in elderly fall and syncope patients

2017 ◽  
Vol 8 (5-6) ◽  
pp. 419-423 ◽  
Author(s):  
J.J. Walgers ◽  
S.C. de Ruiter ◽  
T. Germans ◽  
M.G. Kat ◽  
J.H. Ruiter ◽  
...  
2021 ◽  
Vol 8 (1) ◽  
pp. 14-18
Author(s):  
Mert Besenek

Objective:   In addition to the core symptoms of Autism Spectrum Disorder (ASD); symptoms such as aggression, self-harm, impulsivity, hyperactivity, anxiety, and mood problems are also often present. Medication use is frequent and studies report that 27-40% of ASD patients use at least one psychotropic medication. We aimed to examine the clinical and sociodemographic features and treatment modalities of ASD patients who were referred to a rural hospital in the last two years. Material and Methods: Age, gender, mean diagnosis age (MDA), type of ASD, psychiatric symptoms, medication (if they use one) types, and doses were recorded for 200 children with ASD (who were referred between August 2018 – August 2020) were retrospectively evaluated. Also, patients who were diagnosed with “childhood autism (CA)” and “other ASD diagnoses” were compared. Results: The majority of the patients were male, the MDA value of the all patients was 4.56 (±2.2) years and there were no significant differences between groups regarding MDA (p = 0.053). Most frequently seen psychiatric symptoms were behavioral (33%) and attention problems (21%) and 52.5% of patients (n=105) were using at least one psychotropic medication. Patients with CA had higher rates of psychotropic medication use (p=0.010) and the most frequently used medication group was antipsychotic drugs (92.4%). Conclusion: Treatment approaches utilized in rural hospitals are in line with the universal trends. However, considerably higher MDA compared to previous studies show that; to provide early diagnosis and better prognosis for ASD patients who live in rural areas, new interventions should be promoted by the local and/or general authorities.


2000 ◽  
Vol 2 (3) ◽  
pp. 177-182

Conventional psychiatric diagnosis is founded on symptom description; this then governs the choice of psychotropic medication. This purely descriptive approach resembles a description of diphtheria from the premicrobiology era. Based on current advances in basic and clinical neuroscience, we propose inserting an intermediate level of analysis between psychiatric symptoms and pharmacologic modes of action. Paradigm 1 is to analyze psychiatric symptoms in terms of which higher brain function(s) is (are) abnormal, ie, symptoms should be analyzed as higher brain dysfunction: a case study in obsessive-compulsive disorder reveals pointers in four common symptoms to the higher functions of working memory, emotional overlay, absence of voluntary control, and the ability to evaluate personal mental phenomena. Paradigm 2 is to view psychotropic drugs as modifying normal higher brain functions, rather than merely treating symptoms, which they do only secondarily: thus depression may respond to agents that act on related aspects of mental life derived from higher brain functions, eg, the ability to enhance bonding. We advocate a strategy in which psychiatric illness is progressively reclassified through knowledge in clinical neuroscience and treatment targets are revised accordingly.


2021 ◽  
Author(s):  
Hedda Soloey-Nilsen ◽  
Kristin Nygaard-Odeh ◽  
Magnhild Gangsoey Kristiansen ◽  
Ole Lars Brekke ◽  
Tom Eirik Mollnes ◽  
...  

Abstract BackgroundThere is evidence that brain-derived neurotropic factor (BDNF) plays a protective role in the brain. Peripheral levels of BDNF correlate with its concentration in the brain. Previous studies have revealed lower serum BDNF levels in patients with mental illnesses. In most studies serum BDNF correlates negatively with psychiatric disorders and disease severity. Most studies in this field are on psychiatric diagnosis and personality traits. The aim of our study is to explore associations between general psychiatric symptoms, independent of diagnostic groups, and serum BDNF as well as the inflammatory biomarker high-sensitive CRP (hs-CRP). Comparison between the group regularly using psychotropic medication and those not using psychotropic medication is conducted. Methods The study is a cross sectional study with 132 participants from a general open inpatient psychiatric ward at the Nordland Hospital Trust, Bodø, Norway. Participants were assessed on serum levels of BDNF and hs-CRP. Psychiatric symptoms were assessed by a self-rating scale (Symptom check list, SCL-90- R). Multiple linear regression model was used for statistical analyses of associations between levels of BDNF, hs-CRP and symptoms. Results We found a positive association (p < 0.05), for most SCL-90 symptom clusters with BDNF in the psychotropic medication-free group. No associations were found in the group of patients using psychotropic medication, except one, the Paranoid Ideation cluster (p 0.022). No associations were found between hs-CRP and symptom clusters. Conclusion: We found no relation between symptom clusters and the inflammatory biomarker hs-CRP. Serum BDNF levels were positively associated with intensity of psychiatric symptoms in the group of patients not using psychotropic medication. In the group on psychotropic medication no associations for BDNF were seen. Our findings are in conflict with several previous studies reporting increased hs-CRP as well as decreased rather than increased BDNF in mental suffering.


2000 ◽  
Vol 44 (6) ◽  
pp. 666-676 ◽  
Author(s):  
J. Robertson ◽  
E. Emerson ◽  
N. Gregory ◽  
C. Hatton ◽  
S. Kessissoglou ◽  
...  

Crisis ◽  
2005 ◽  
Vol 26 (4) ◽  
pp. 160-169 ◽  
Author(s):  
Paul S. Links ◽  
Rahel Eynan ◽  
Jeffrey S. Ball ◽  
Aiala Barr ◽  
Sean Rourke

Abstract. Assertive community treatment appears to have limited impact on the risk of suicide in persons with severe and persistent mental illness (SPMI). This exploratory prospective study attempts to understand this observation by studying the contribution of suicidality to the occurrence of crisis events in patients with SPMI. Specifically, an observer-rated measure of the need for hospitalization, the Crisis Triage Rating Scale, was completed at baseline, crisis occurrence, and resolution to determine how much the level of suicidality contributed to the deemed level of crisis. Second, observer-ratings of suicidal ideation, the Modified Scale for Suicide Ideation, and psychopathology and suicidality, Brief Psychiatric Rating Scale, were measured at baseline, crisis occurrence, and resolution. A self-report measure of distress, the Symptom Distress Scale, was completed at baseline, crisis occurrence, and resolution. Finally, the patients' crisis experiences were recorded qualitatively to compare with quantitative measures of suicidality. Almost 40% of the subjects experienced crisis events and more than a quarter of these events were judged to be severe enough to warrant the need for hospitalization. Our findings suggest that elevation of psychiatric symptoms is a major contributor to the crisis occurrences of individuals with SPMI; although the risk of suicide may have to be conceived as somewhat separate from crisis occurrence.


Crisis ◽  
2019 ◽  
Vol 40 (5) ◽  
pp. 326-332
Author(s):  
Ivonne Andrea Florez ◽  
Devon LoParo ◽  
Nakia Valentine ◽  
Dorian A. Lamis

Abstract. Background: Early identification and appropriate referral services are priorities to prevent suicide. Aims: The aim of this study was to describe patterns of identification and referrals among three behavioral health centers and determine whether youth demographic factors and type of training received by providers were associated with identification and referral patterns. Method: The Early Identification Referral Forms were used to gather the data of interest among 820 youth aged 10–24 years who were screened for suicide risk (females = 53.8%). Descriptive statistics and binary logistic regressions were conducted to examine significant associations. Results: Significant associations between gender, race, and age and screening positive for suicide were found. Age and race were significantly associated with different patterns of referrals and/or services received by youths. For providers, being trained in Counseling on Access to Lethal Means was positively associated with number of referrals to inpatient services. Limitations: The correlational nature of the study and lack of information about suicide risk and comorbidity of psychiatric symptoms limit the implications of the findings. Conclusion: The results highlight the importance of considering demographic factors when identifying and referring youth at risk to ensure standard yet culturally appropriate procedures to prevent suicide.


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