Eating Disorders in Schizophrenia

2017 ◽  
Vol 41 (S1) ◽  
pp. S284-S284 ◽  
Author(s):  
R. Sallemi ◽  
S. Hentati ◽  
I. Feki ◽  
J. Masmoudi ◽  
M. Moala
Keyword(s):  
Eating Disorders ◽  
Negative Impact ◽  
Female Gender ◽  
University Hospital ◽  
Atypical Neuroleptics ◽  
Optimal Care ◽  
Duration Of Disease ◽  
The Mean ◽  
Competing Interest ◽  
Data Collections

BackgroundDue to their frequency and negative impact on quality of life, eating disorders in schizophrenia need to be considered and highlighting.ObjectiveTo identify the risk of eating disorders (ED) and its correlates among mental patients.MethodsIt was a descriptive and analytic study. It included 53 inpatients with DSM-5 diagnoses of schizophrenia or schizoaffective disorder, followed in the department of Psychiatry at the Hedi Chaker University Hospital of Sfax in Tunisia, during the three months of August, September and October 2016. Data collections were conducted using questionnaire exploring sociodemographic and medical data. The SCOFF (sick, control, one, fat, food) Questionnaire was used to screen ED. A total score of ≥ 2 was used as a cutoff point to select persons at risk of ED.ResultsThe average age of our patients was 30.47 ± 9.5 years old. The majority of our patients was male (71.7%) and single (71%). The mean of extra Body mass was 27.9. The mean duration of disease was 9.9 ± 8.1 years and patients were mostly (54%) in atypical neuroleptics. According to the SCOFF Questionnaire, 35.8% had a risk of ED. Female gender and treatment with atypical neuroleptics were significantly associated to ED risk with respectively P = 0.02 and P = 0.038.ConclusionEating disorders remain underestimated among patients suffering from schizophrenia. Yet, its screening prevention and management are crucial and must be multidisciplinary for optimal care.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals POS0998 SPONDYLOARTHRITIS AND SLEEP DISORDERS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 767.2-768
Author(s):  
S. Lahrichi ◽  
K. Nassar ◽  
S. Janani
Keyword(s):  
Functional Impairment ◽  
Sleep Disturbances ◽  
Negative Impact ◽  
University Hospital ◽  
Quality Of Sleep ◽  
The Mean ◽  
Sleep Deficit ◽  
Impaired Sleep ◽  
The Impact

Background:Spondyloarthropathies (SpA) are a group of chronic and progressive diseases, characterized in particular by a progressive stiffening of the spine, spreading to neighboring joints or to certain tissues, which could lead in the long term to progressive stiffening and functional impairment. This conditioncancauseinsomnia problems and impaired sleep quality.Objectives:To assess the impact of SpA on the quality of sleep.Methods:This is a retrospective study over a period of 4 years from January 2015 to December 2019, including all the medical records of patients with SpA followed in the Department of Rheumatology of the University Hospital of Ibn Rochd, Casablanca. We evaluated for each patient two validated scores: the Epworth somnolence scale rated from 0 to 24, and the Pittsburgh sleep score rated from 0 to 21 with 7 components. Patients with a psychiatric history or who were followed up for neurological pathologies were excluded.Results:178 patients were included. 60.67% were men with an average age of 36.32 years (14-68 years). 45.01% had axial SpA, 29.77% had psoriatic arthritis, and 25.22% were followed for SpA associated with inflammatory bowel disease. 45% had associated comorbidities: there were 18 diabetics and 34 hypertensive, 16.58% were smokers. Clinically, 85.42% presented a back pain initially on examination, 55% presented a polyarthralgia, and 39.88% an oligoarthritis. 63% had radiological sacroiliitis, and 35.14% had bilateral coxitis. 13.48% had a positive HLA B27 and 58.89% had a positive inflammatory assessment with very high activity indices,with a mean of 4.6. 64.66% of the patients received NSAIDs,of which 11% responded well. 57% were treated with csDMARDs, and 17.86% were treated with biologics. At the time of our study, the mean visual analog scale was 5.84 ± 1.7 out of 10 (2-9). The mean Epworth score was 8.38 ± 5.2 (0-21). 56.1% of patients had no sleep debt, 33.3% had a sleep deficit, and only 10.6% had signs of drowsiness. For the overall Pittsburgh score, the mean was 7.02 ± 3.6 (1-18). The mean of “subjective quality of sleep” was 1.12, “sleep latency” was 1.22, “duration of sleep” was 1.06, “usual sleep efficiency” was 0.74, “Sleep disturbance” of 1.28, “use of a sleep medication” of 0.54, and the average of the component concerning “poor shape during the day” was 1.03 out of 3. The LEQUESNE index went from an average of 6 to 8, which corresponds to an average handicap (P = 0.2) over a period of 3 years. 68% of the patients had an alteration in the quality of sleep, starting on average three years after the onset of symptoms. 11% reported having experiencedanxiety and depressive symptoms, and reported having used antidepressants or anxiolytics in the past 5 years.Conclusion:Our study showed the negative impact of SpA on the duration and overall quality of sleep. The degree of pain as well as functional impairment can cause and worsen sleep disturbances in SpA. We have shown that the Pittsburg score increases significantly with the increase of pain.The Lequesne score and that the Epworth score increase with disease activity[1].References:[1]StolwijkC,vanTubergenA,Castillo-OrtizJD,BoonenA.Prevalenceofextra-articularmanifestationsinpatientswithankylosingspondylitis:asystematicreviewandmeta-analysis.AnnRheumDis2015;74:65—73.Disclosure of Interests:None declared.

Severity of traumatic events in patients with eating disorders. A case-control study

2016 ◽  
Vol 33 (S1) ◽  
pp. S165-S166
Author(s):  
A.M. Pignatelli ◽  
C. Loriedo ◽  
M. Biondi ◽  
P. Girardi ◽  
J. Vanderlinden ◽  
...  
Keyword(s):  
Eating Disorders ◽  
Childhood Abuse ◽  
Emotional Abuse ◽  
Traumatic Events ◽  
University Hospital ◽  
Traumatic Experiences ◽  
Emotional Neglect ◽  
Psychiatric Outpatient Clinic ◽  
Competing Interest ◽  
Age Range

IntroductionA high proportion of individuals with eating disorders (EDs) report childhood abuse and neglect. The prevalence of traumatic events in ED patients has been extensively investigated; less is known about their self-perceived–and reported–severity. Objectives/Aims: We aimed to assess in ED patients vs. healthy controls the severity, i.e., duration, perpetrator, and subjective impact, of sexual, physical, and emotional traumas suffered from 0 to 18 years, paying particular attention to emotional neglect.MethodsFifty-seven consecutive DSM-V ED patients (91.2% females; age range: 18–42 years) were recruited at the Psychiatric Outpatient Clinic of our University Hospital. Ninety controls (78.9% females; age range: 20–39 years) were also recruited. Among ED patients, 43.9% had restrictive anorexia nervosa (AN), 29.8% binge/purging AN, 26.3% bulimia nervosa. Individuals completed the Eating Disorder Inventory-2 (EDI-2) and the Traumatic Experiences Checklist (TEC).ResultsThe severity of all traumatic events, according to the TEC total score, was significantly higher in ED patients than controls (P < 0.001). Moreover, ED patients showed significantly higher scores with regard to emotional neglect (P < 0.001) and emotional abuse (P < 0.001). The same can be said for physical traumas (P < 0.01) and physical abuse (P < 0.01), although with a lower significance, and for sexual abuse (P < 0.05), with an even lower significance. No difference in the severity of sexual harassment was found.ConclusionsAll types of traumas, especially neglect, can occur in ED patients and controls, however they are reported as more severe by ED patients.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Total Blood Lymphocyte Count Alteration During and after Pregnancy

2016 ◽  
pp. 1 ◽  
Author(s):  
Gökçen Örgül ◽  
Burcu Soyak ◽  
Oytun Portakal ◽  
Meral Beksaç ◽  
M. Sinan Beksaç
Keyword(s):  
Lymphocyte Count ◽  
Blood Lymphocyte ◽  
Complete Blood Count ◽  
Negative Impact ◽  
Post Partum ◽  
University Hospital ◽  
Base System ◽  
Total Blood ◽  
The Mean ◽  
The Impact

<p><strong>Objective:</strong> To investigate the impact of gestational changes on blood lymphocyte count in healthy pregnancies. <br /><strong>Study Design:</strong> This retrospective study is consisted of 108 consecutive normal pregnancies who delivered at our department in December 2015. High-risk pregnancies with poor neonatal outcome and pregnancies with maternal disorders which may affect lymphocyte counts were excluded from the study. “Complete blood count” results of the patients were obtained from the computerized data base system of Hacettepe University Hospital. Blood samples of patients which were withdrawn a) prior to pregnancy (1-6 months before getting pregnant), b) during pregnancy (11-14th gestational weeks) and c) post-partum first day were used in this study.<br /><strong>Results:</strong> The mean blood lymphocyte count was 2049.07 (±758.69) in patients before their pregnancies. The mean lymphocyte count decreased to 1850.93 and 1625 during pregnancy and after delivery respectively. A statistically significant decrease was found between three periods (before, during, and postpartum 1st day) (p:0.003).<br /><strong>Conclusion:</strong> We have shown a significant decrease in total lymphocyte levels during pregnancy, consistent with the data presented in the literature. Pregnancy and related hormones have a negative impact on total blood lymphocyte level.<br /><br /></p>

Clinical profile of patients hospitalized for delirium

2017 ◽  
Vol 41 (S1) ◽  
pp. S704-S704
Author(s):  
F. Smaoui ◽  
M. Frikha ◽  
I. Bouchhima ◽  
O. Hdiji ◽  
N. Farhat ◽  
...  
Keyword(s):  
Sex Ratio ◽  
Descriptive Study ◽  
Clinical Syndrome ◽  
Clinical Profile ◽  
University Hospital ◽  
First Episode ◽  
Memory Disorder ◽  
The Mean ◽  
Competing Interest ◽  
Medical Histories

IntroductionDelirium is a common clinical syndrome characterized by acute disruption of all cognitive and behavioural functions.Objectives– Draw up an epidemiological and clinical profile of patients hospitalised for delirium;– Assess different pathologies involved.MethodsWe conducted a retrospective and descriptive study, in the neurology department at Habib Bourguiba university hospital, Sfax, Tunisia, at the period from 2009 to 2013. We included 52 patients hospitalised for delirium. Socio-demographic and clinical data were collected from patient files.ResultsThe mean age was 66.5 years. The majority (73.1%) were elderly patients (> = 60 years). Sex-ratio (M/F) was 1.73. It was the first episode in 96.2%.Medical histories were cardiovascular in 55.8%, endocrinal in 25%, neurological in 11.5% and psychiatric in 13.5%. The beginning of the signs was brutal in 55.8% of cases. The reported symptoms were: disorientation in time and space (76.9%) and behaviour disturbance (63.5%), memory disorder (23.1%), headaches (26.9%) and hallucinations (17.3%). Organic etiologies were noted in 75% of cases: vascular 42.30%, metabolic 11.50%, infectious 11.5%, tumoral 3.9% and iatrogenic 3.8%. Delirium grafted on dementia was retained in 5.8% of cases.ConclusionDelirium is associated with increased mortality. Its prevention is essential and requires recognition of risk situations.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Psychotropic Polypharmacy among Elderly Patients with Mental Illness in a Malaysian University Hospital: A 10-Year Review of Hospital Databases

2021 ◽  
Vol 16 (2) ◽  
pp. 249-262
Author(s):  
Luke Sy-Cherng Woon ◽  
Keyword(s):  
Elderly Patients ◽  
Psychiatric Diagnosis ◽  
Female Gender ◽  
Median Number ◽  
Multiple Regression Model ◽  
University Hospital ◽  
Sociocultural Factors ◽  
Medical Comorbidities ◽  
The Mean ◽  
Data Length

Psychotropic polypharmacy among elderly patients is problematic due to their multiple comorbidities. This study investigated psychotropic polypharmacy among elderly patients discharged from a Malaysian university hospital and its associated factors. Discharges of patients aged 65 years or above from the psychiatric wards from 2010 to 2019 were reviewed. Sociodemographic data, length of stay (LOS), psychiatric and other diagnoses, and psychotropic prescription upon discharge were extracted from electronic databases. Multiple logistic regression was conducted with age, gender, race, marital status, main psychiatric diagnosis, LOS, and the number of medical comorbidities as independent variables, and polypharmacy (>2 psychotropics) as the dependent variable. There were 354 discharges in this period. The mean age was 72.4 years (SD=5.9 years); 63.0% were female and 39.8% were Malays. Most were married (84.2%). The commonest category of psychiatric diagnosis was mood disorders (54.5%). A total of 76.8% of the discharges involved one or more medical comorbidities. The median number of psychotropics was two, with 38.1% prescribed three or more psychotropics. In the multiple regression model, female gender, Malay race, and being married were significantly associated with psychotropic polypharmacy. Sociocultural factors may contribute to psychotropic polypharmacy among elderly patients. Such factors require further investigations to elucidate their roles.

scholarly journals ESSENTIAL HYPERTENSION

2018 ◽  
Vol 25 (06) ◽  
pp. 854-859
Author(s):  
Imran Khan ◽  
Abdul Ghaffar Dars ◽  
Nisar Ahmed Shah ◽  
Syed Zulfiquar Ali Shah
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Systolic Blood Pressure ◽  
Postpartum Hemorrhage ◽  
Female Gender ◽  
University Hospital ◽  
Cross Sectional ◽  
Male And Female ◽  
Treatment Status ◽  
The Mean

Objectives: To determine the frequency of microalbuminuria in patients withessential hypertension for postpartum hemorrhage. Study Design: Cross sectional study.Setting: Department of Medicine at Liaquat University Hospital Hyderabad. Period: Six months(from January 2015 to June 2015). Patients and Methods: All the patients ≥35 years of age bothgender had essential hypertension were enrolled and explored for microalbuminuria by urineexamination while the data was analyzed in SPSS 16. Results: Total one hundred subjects withessential hypertension were studied and explored for microalbuminuria. The mean age ±SDof for overall population was 52.82±7.85 and it was 51.23±8.21 and 53.32±6.52 in male andfemale gender respectively. The overall mean ± SD for systolic blood pressure was 170±12.62whereas it was 160.82±10.82 and 165±11.92 in male and female gender respectively. Themean ±SD for blood pressure (diastolic) was 105±71 while it was 95.01±7.21 and 100.82±6.42in male and female sex respectively. The duration of hypertension as mean ±SD was 3.72±2.52in overall population. The microalbuminuria was identified in 59 (59%) patients with statisticalsignificance in relation to age (p=0.00), gender (p=0.00), duration of hypertension (p=0.01),treatment status (p= 0.04), hypertension (p=0.002), BMI (p=0.05) and residence (p=0.00).Conclusion: In present series the prevalence for microalbuminuria in essential hypertensionwas detected as 59% and correlate with age, gender and duration and treatment status of thepatients along with raised systolic and diastolic blood pressure

scholarly journals Clinical Characteristics of Atrial Fibrillation in Saudi Women Cohort and Its Clinical Impact in a Tertiary University Hospital

2015 ◽  
Vol 22 (2) ◽  
pp. 11-17
Author(s):  
Kamal W. AlGhalayini
Keyword(s):  
Atrial Fibrillation ◽  
Negative Impact ◽  
Blood Pressure Measurement ◽  
Density Lipoprotein ◽  
International Normalized Ratio ◽  
Thyroid Stimulating Hormone ◽  
University Hospital ◽  
Saudi Women ◽  
The Mean ◽  
Stimulating Hormone

A retrospective study was conducted to evaluate the characteristics of atrial fibrillation in a cohort of Saudi women, and its impact on morbidity. A complete medical history was obtained and all participants underwent a complete review of clinical data including electrocardiogram, echocardiogram, blood pressure measurement, and thyroid examination. The following laboratory examinations were performed: international normalized ratio; thyroid stimulating hormone; triiodothyronine; thyroxine; total cholesterol; triglyceride; low-density and high-density lipoprotein. A history of hospitalizations, stroke and in-hospital mortality were recorded. We recruited 84 women; the mean age was 61.8 years and the mean body mass index was 28.45 kg/m2. The mean hemoglobin level of the patients was 12.2 g/dL and the mean thyroid stimulating hormone level was 3.75 mIU/L. The target international normalized ratio was achieved in 58% of treated patients; 70% of the under target International Normalized Ration patients had been hospitalized more than once and 19% had suffered a stroke. Overall, international normalized ratio demonstrates gaps in the management of women with atrial fibrillation, and the negative impact on patient outcome, indicating the need to tailor treatment plans to the goals and requirements of these patients.  

scholarly journals Association of autoimmune diseases with celiac disease and its risk factors

2019 ◽  
Vol 35 (6) ◽  
Author(s):  
Yusuf Kayar ◽  
Ramazan Dertli
Keyword(s):  
Risk Factors ◽  
Celiac Disease ◽  
Autoimmune Diseases ◽  
Age At Onset ◽  
Female Gender ◽  
Turkish Population ◽  
Hashimoto Thyroiditis ◽  
Dietary Compliance ◽  
Duration Of Disease ◽  
The Mean

Objectives: Autoimmune Diseases (AIDs) are detected in celiac patients. Our purpose was to determine the AIDs that are associated with celiac disease and related risk factors in the Turkish population. Methods: The study included 230 celiac patients who were diagnosed and followed-up in our clinics between 2015-2019. All AIDs that accompanied the celiac disease were recorded, and their association with risk factors was analyzed. Results: The mean age of the patients was 35.6±10.6 years (age range:18-72). A total of 58(25.2%) patients were male and the mean age at onset of disease was 29.1±6.5 years. The duration of disease follow-up was 6.5±4.6 years. One hundred and twenty two (53%) patients were on a strict diet, and 72(31.3%) patients had accompanying AID. Hashimoto thyroiditis was found in 39(17%) patients, asthma in 16(7%) patients as the most common comorbidities. There was a significant relation between AID and female gender, age of diagnosis being <40 years, duration of disease, non-GIS symptoms at the time of admission, and non-employment status. Conclusion: Screening other AIDs in celiac patients are important, especially in individuals who have risk factors. Considering that many AIDs may develop in the future despite dietary compliance, patients should be followed with a multidisciplinary approach. doi: https://doi.org/10.12669/pjms.35.6.821 How to cite this:Kayar Y, Dertli R. Association of autoimmune diseases with celiac disease and its risk factors. Pak J Med Sci. 2019;35(6):1548-1553.   doi: https://doi.org/10.12669/pjms.35.6.821 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The Effects of Hopelessness and Some Variables on Metabolic Syndrome in Schizophrenia Patients

2021 ◽  
pp. 105477382110572
Author(s):  
Yadigar Çevik Durmaz ◽  
Tuğba Menekli ◽  
Berna Ersoy Özcan
Keyword(s):  
Metabolic Syndrome ◽  
Drug Treatment ◽  
Atypical Antipsychotics ◽  
Personal Information ◽  
Descriptive Study ◽  
University Hospital ◽  
Clinical Variables ◽  
Psychiatry Clinic ◽  
Duration Of Disease ◽  
The Mean

This is a descriptive study conducted to determine the prevalence of Metabolic Syndrome (MetS) in Schizophrenia patients and identify the effects of hopelessness and some variables on MetS. The study was conducted at the Psychiatry Clinic of a university hospital in Turkey between May and August 2020 with 105 schizophrenia patients receiving treatment as inpatients. The data of the study were collected by a Personal Information Form, a Physiological Measurements Form and (BHS). The data were analyzed by using SPSS 25. The mean age of the patients was 35.31 ± 9.07, their mean duration of disease was 11.35 ± 9.07 years, and 60.0% of the patients were using atypical antipsychotics as their latest drug treatment. 42.9% of the patients had MetS, while the mean hopelessness level of those with MetS was 10.84 ± 3.81. It was determined that hopelessness levels and some sociodemographic (age) and clinical variables significantly predicted the MetS status in the schizophrenia patients.

scholarly journals To Determine the Frequency of Thrombocytopenia in Pre Eclamptic Presented at Isra University Hospital

2021 ◽  
pp. 242-247
Author(s):  
Hafiza Khatoon ◽  
Rukhsana Ahmed ◽  
Ambreen Naz ◽  
Nousheen Mushtaq ◽  
Asma Irfan ◽  
...  
Keyword(s):  
Gestational Age ◽  
High Frequency ◽  
Urban Areas ◽  
Maternal Age ◽  
Descriptive Study ◽  
University Hospital ◽  
Cross Sectional ◽  
Preeclamptic Patient ◽  
Duration Of Disease ◽  
The Mean

Objective: To determine the frequency of thrombocytopenia in pre-eclamptic women presented at Isra University Hospital Hyderabad. Patients and Methods: This cross sectional descriptive study of six months study was conducted at Isra university hospital from April 2019 to September 2019. All the patients between ≥18 - 45 years of age diagnosed preeclampsia were admitted and evaluated for thrombocytopenia. Results: During six month study period, total of 177 patients with preeclampsia were evaluated for thrombocytopenia. The majority of patients were from urban areas 125/177 (70.6%). The mean ±SD for maternal and gestational age of the preeclamptic patient was 32.75±8.85 and 28.75±7.63 whereas the mean platelet count was 93200±10.74 respectively. The majority of the patients were 21-30 years of age (54.8%) and the finding was statistically significant with gestational age [p=0.002]. The thrombocytopenia was observed in 99/177 (55.9%) and is statistically with relation to maternal age, gestational age and parity while in context to gravida and duration of disease it is non significant. Conclusion: A significantly high frequency of thrombocytopenia (55.9%) was recorded in the patients with preeclampsia and is statistically with relation to maternal and gestational age and parity.

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