scholarly journals POS0998 SPONDYLOARTHRITIS AND SLEEP DISORDERS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 767.2-768
Author(s):  
S. Lahrichi ◽  
K. Nassar ◽  
S. Janani

Background:Spondyloarthropathies (SpA) are a group of chronic and progressive diseases, characterized in particular by a progressive stiffening of the spine, spreading to neighboring joints or to certain tissues, which could lead in the long term to progressive stiffening and functional impairment. This conditioncancauseinsomnia problems and impaired sleep quality.Objectives:To assess the impact of SpA on the quality of sleep.Methods:This is a retrospective study over a period of 4 years from January 2015 to December 2019, including all the medical records of patients with SpA followed in the Department of Rheumatology of the University Hospital of Ibn Rochd, Casablanca. We evaluated for each patient two validated scores: the Epworth somnolence scale rated from 0 to 24, and the Pittsburgh sleep score rated from 0 to 21 with 7 components. Patients with a psychiatric history or who were followed up for neurological pathologies were excluded.Results:178 patients were included. 60.67% were men with an average age of 36.32 years (14-68 years). 45.01% had axial SpA, 29.77% had psoriatic arthritis, and 25.22% were followed for SpA associated with inflammatory bowel disease. 45% had associated comorbidities: there were 18 diabetics and 34 hypertensive, 16.58% were smokers. Clinically, 85.42% presented a back pain initially on examination, 55% presented a polyarthralgia, and 39.88% an oligoarthritis. 63% had radiological sacroiliitis, and 35.14% had bilateral coxitis. 13.48% had a positive HLA B27 and 58.89% had a positive inflammatory assessment with very high activity indices,with a mean of 4.6. 64.66% of the patients received NSAIDs,of which 11% responded well. 57% were treated with csDMARDs, and 17.86% were treated with biologics. At the time of our study, the mean visual analog scale was 5.84 ± 1.7 out of 10 (2-9). The mean Epworth score was 8.38 ± 5.2 (0-21). 56.1% of patients had no sleep debt, 33.3% had a sleep deficit, and only 10.6% had signs of drowsiness. For the overall Pittsburgh score, the mean was 7.02 ± 3.6 (1-18). The mean of “subjective quality of sleep” was 1.12, “sleep latency” was 1.22, “duration of sleep” was 1.06, “usual sleep efficiency” was 0.74, “Sleep disturbance” of 1.28, “use of a sleep medication” of 0.54, and the average of the component concerning “poor shape during the day” was 1.03 out of 3. The LEQUESNE index went from an average of 6 to 8, which corresponds to an average handicap (P = 0.2) over a period of 3 years. 68% of the patients had an alteration in the quality of sleep, starting on average three years after the onset of symptoms. 11% reported having experiencedanxiety and depressive symptoms, and reported having used antidepressants or anxiolytics in the past 5 years.Conclusion:Our study showed the negative impact of SpA on the duration and overall quality of sleep. The degree of pain as well as functional impairment can cause and worsen sleep disturbances in SpA. We have shown that the Pittsburg score increases significantly with the increase of pain.The Lequesne score and that the Epworth score increase with disease activity[1].References:[1]StolwijkC,vanTubergenA,Castillo-OrtizJD,BoonenA.Prevalenceofextra-articularmanifestationsinpatientswithankylosingspondylitis:asystematicreviewandmeta-analysis.AnnRheumDis2015;74:65—73.Disclosure of Interests:None declared.

2021 ◽  
pp. 25-27
Author(s):  
Umesh kr. Mishra ◽  
Sunita Tiwari ◽  
Sumit Rungta ◽  
Pooja Mishra ◽  
Gulam Akhtar

Background: Night time reux has been shown to be associated with fragmented sleep. However, few studies have assessed the quality of sleep on gastroesophageal reux and the impact of gastroesophageal reux on reported quality of sleep and quality of sleep on gastroesophageal reux. The aims of this study were to evaluate the quality of sleep and other parameters in patients with gastroesophageal reux disease.50 Subjects with typical GERD symptoms ≥3 times a week and All subjects were administered 3 questionnaires: PSQI , ESS, GERD-HRQL . All the subjects underwent nocturnal polysomnography and completed a all 3 questionnaire before NPSG. Results: Overall ,the mean percentage of N1 was 9.10±9.74 ,N2 was 83.97±13.81 , N3 was 3.44±4.16 , N4 was 0.60±2.04 , REM was 2.14±3.79 , PSQI was 12.48±1.23 , ESS was 11.80±0.76 , TST (hr) was 5.19±0.74 , SPT(hr) was 6.58±0.77 , sleep efciency(%) was 52.50±27.16 , Latency (mint) was 22.79±30.85 , REM Latency (mints) was 96.99±151.86 ,and Microarousal index was 36.05±25.93 . To assess the potential impact of sleep quality via nocturnal polysomnography on severity of gastroesophageal reux , we performed correlations between the GERD questionnaire and nocturnal polysomnography reports . We observed that PSQI(r= -0.285, p<0.045) , ESS(r=0.206, p=0.05) , N1(r=0.202 , p>0.160) , N2(r=- 0.045 ,p>0.758) , N3(r=-0.079, p>0.583) , N4(r-0.209 ,p>0.145),REM(r=0.045 ,p>0.756) , TST(r=0.036 ,p>0.803), SPT(r=0.015,p>0.917) , Sleep Efciency (r=-0.113,p>0.435) , Sleep Latency (r=-0.045 ,p>0.756), REM Latency (r=0.165, p >0.253), Microarousal index (r=0.058 , p>0.683). Conclusions: Gastroesophageal reux disease and sleep disorders are extremely prevalent conditions, and it seems intuitive that there must be some overlap between the two. Sleep disorders may in fact be one of the most prevalent of the extraesophageal complications of GERD and often goes unrecognized.


2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Fandresena Arilala Sendrasoa ◽  
Naina Harinjara Razanakoto ◽  
Volatantely Ratovonjanahary ◽  
Onivola Raharolahy ◽  
Irina Mamisoa Ranaivo ◽  
...  

Background. Psoriasis is a chronic, inflammatory, and multifactorial dermatosis that impairs quality of life (QoL). Health-related QoL has become an important element in medical decision-making along with the effectiveness and the harmlessness of the treatments. Objective. To assess the impact of psoriasis in the QoL of patients with psoriasis by using the DLQI scales. Methods. A cross-sectional study from January to June 2018 was conducted in the Department of Dermatology of the University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar, including patients more than 18 years old with mild to severe psoriasis. The severity of psoriasis was assessed using the “Psoriasis Area and Severity Index (PASI)”. QoL of patients with psoriasis was evaluated by using the DLQI scales. Results. 80 patients were included, their mean age was 36.5 years, and the male to female was 1.5 : 1. The mean DLQI score was 13.8. Symptoms, feelings, and psychic were the most altered dimensions. QoL was impaired in young patients, single, having medium level education. Even though patients with disease duration more than 5 years had higher DLQI score than other patients, the difference was not statistically significant (p=0.36). Furthermore, the clinical presentation of psoriasis did not influence the patient’s QoL (p=0.73). Patients with nail involvement had QoL impaired but the difference with another localization was not statistically significant (p=0.2). The quality of life was influenced by body area involved. The higher the body surface area involved, the more QoL is impaired (p=0.002). Furthermore, the higher the PASI, the more QoL is altered (p=0.002). Conclusion. Psoriasis has a negative impact in the quality of life in Malagasy patients with psoriasis, especially in younger and single patients. Worse quality of life is correlated to severity of psoriasis.


Author(s):  
Gökçen Örgül ◽  
Burcu Soyak ◽  
Oytun Portakal ◽  
Meral Beksaç ◽  
M. Sinan Beksaç

<p><strong>Objective:</strong> To investigate the impact of gestational changes on blood lymphocyte count in healthy pregnancies. <br /><strong>Study Design:</strong> This retrospective study is consisted of 108 consecutive normal pregnancies who delivered at our department in December 2015. High-risk pregnancies with poor neonatal outcome and pregnancies with maternal disorders which may affect lymphocyte counts were excluded from the study. “Complete blood count” results of the patients were obtained from the computerized data base system of Hacettepe University Hospital. Blood samples of patients which were withdrawn a) prior to pregnancy (1-6 months before getting pregnant), b) during pregnancy (11-14th gestational weeks) and c) post-partum first day were used in this study.<br /><strong>Results:</strong> The mean blood lymphocyte count was 2049.07 (±758.69) in patients before their pregnancies. The mean lymphocyte count decreased to 1850.93 and 1625 during pregnancy and after delivery respectively. A statistically significant decrease was found between three periods (before, during, and postpartum 1st day) (p:0.003).<br /><strong>Conclusion:</strong> We have shown a significant decrease in total lymphocyte levels during pregnancy, consistent with the data presented in the literature. Pregnancy and related hormones have a negative impact on total blood lymphocyte level.<br /><br /></p>


2019 ◽  
Vol 5 (2) ◽  
pp. 187-195
Author(s):  
Šárka Vévodová ◽  
Filip Havelka ◽  
Jiří Vévoda ◽  
Bronislava Grygová

Introduction: Psoriasis is a chronic skin disease characterized by scaly patches affecting approximately 2-5% of the population. The disease has a negative impact on quality of life and, therefore, psoriatic patients often develop depression. Our work deals with quality of life and depression in psoriasis sufferrers and strives to determine the correlation between their quality of life and depression. Methods: The research took place in the University Hospital Olomouc in 2017 and used questionnaires WHOQOL-BREF and BDI-II. 50 patients with psoriasis were chosen randomly. To process the data we used Mann-Whitney test (the level of significance = 5%) and Spearman´s correlation coefficient (the level of significance = 1%). Results: The results proved that psoriasis has a significant impact on quality of life. The scores for the overall life quality as well as for individual domains were significantly lower in psoriatic patients than in the control group (p&lt;0.001). The degree of depression in patients with psoriasis showed statistically significant correlation in all domains of the quality of life. We proved negative correlation in the overall quality of life (rs =- 0.691**), physical condition (rs =-0.499**), social relations (rs =-0.546**), overall health (rs =-0.396**), and environment (rs =-0.386**). Conclusion: With regard to the ascertained negative correlation between psoriasis and depression and lower quality of life of the sufferers compared to the healthy population, it is essential for healthcare professionals to pay attention not only to somatic manifestations of the disease but also to the patients´ mental health.


2014 ◽  
Author(s):  
Ahmed Waqas ◽  
Spogmai Khan ◽  
Waqar muhammad Sharif ◽  
Uzma khalid ◽  
Asad Ali

Introduction: Medicine is one of the most stressful fields of education because of its highly demanding professional and academic requirements. Psychological stress, anxiety, depression and sleep disturbances are highly prevalent in medical students. Methods: This cross-sectional study was undertaken at CMH Lahore Medical College and Institute of Dentistry in Lahore, Pakistan, and was approved by the CMH LMC Research Ethics Committee. Students enrolled in all yearly courses for the MBBS degree were included. The questionnaire consisted of four sections: 1) demographics 2) a table listing 34 potential stressors, 3) the 14-item Perceived Stress Scale (PSS-14), and 4) the Pittsburgh Quality of Sleep Index (PSQI). Data were analyzed in SPSS v. 20. Logistic regression was run to identify associations between group of stressors, gender, year of study, student’s background, stress and quality of sleep. Results: Total response rate was 93.9% (263/280 respondents returned the questionnaire). The mean PSS-14 score was 30.04 (6.97). Logistic regression analysis showed that cases of high-level stress were associated with year of study and academic-related stressors only. Univariate analysis identified 157 cases with high stress levels (59.7%). The mean PSQI score was 8.09 (3.12). According to PSQI score, 203/263 respondents (77.02%) were poor sleepers. Logistic regression showed that mean PSS-14 score was a significant predictor of PSQI score (OR 1.99, P<0.05). Conclusion: We found a very high prevalence of academic stress and poor sleep quality among medical students. Many medical students reported using sedatives more than once a week. Academic stressors contributed significantly to stress and sleep disorders in medical students.


2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S193-S194
Author(s):  
Sanne Brederoo ◽  
Jacqueline De Vries ◽  
Janna De Boer ◽  
Mascha Linszen ◽  
Maya Schutte ◽  
...  

Abstract Background Although previous studies reported a link between sleep dysfunction and psychotic symptoms, more detailed information is needed to translate this association into clinical practice. This study investigates the impact of different aspects of sleep quality on prevalence, type and severity of psychotic-like experiences, in a large general population sample. In doing so, we distinguish between hallucinations in the auditory (AH) and visual (VH) domains and delusions, to arrive at a more comprehensive understanding of the detrimental effects of impaired sleep. Methods An online survey was used to gather information on self-reported psychotic-like experiences and sleep quality in a sample of 10.301 Dutch participants (median age 32 yrs; 68.9% females). The Questionnaire for Psychotic Experiences (QPE) was used to assess aspects of AH and VH. A subset of the participants also filled-out a second part of the QPE regarding occurrence of delusion. Furthermore, a measure of general sleep quality was derived based on seven sleep domains as assessed using the Pittsburgh Sleep Quality Index (PSQI). Binomial logistic regression was used to investigate the effects of the seven sleep domains on the likelihood that participants had experienced hallucinations in the preceding week, using 3324 participants with and a random subsample of 3391 participants without such experiences. The same analysis was performed on the data regarding delusions, using 438 participants with and a random subsample of 445 participants without delusions in the past week. Reported odds ratios (OR) reflect the increment in likelihood of occurrence of hallucinations and delusions. To further assess whether impaired sleep affects the level of distress caused by hallucinations, participants were divided into ‘good’ and ‘poor’ sleepers using a cut-off score of 5 points on the total PSQI score. Chi-square tests were then used to compare the two groups on occurrence of distressing vs non-distressing AH and VH. Results Impaired sleep showed to entail significant predictors of the prevalence of hallucinations. Specifically, sleeping less than 5 hours a night (OR 1.88), having sleep disturbances more than 3 times a week (OR 5.81), the use of sleep medication more than 2 times a week (OR 1.61) and decreased daytime functioning more than 3 times a week (OR 1.87) increased the odds to experience hallucinations, as compared to participants without these sleep difficulties. Furthermore, experiencing sleep disturbances more than 2 times a week (OR 9.24) and decreased daytime functioning more than 2 times a week (OR 5.53) also strongly increased the odds to experience delusions. Subjective sleep quality, sleep latency, and sleep efficiency were not significant predictors for the prevalence of hallucinations or delusions. Importantly, sleep impairment also affected the experienced distress as caused by hallucinations. A larger proportion of the poor sleepers than of the good sleepers experienced distressing AH (p &lt; .001) and reported that the AH had a negative impact on their functioning (p &lt; .001). Likewise, a larger proportion of the poor sleepers than of the good sleepers reported distressing VH (p &lt; .001) and reported a negative impact of VH on their functioning (p &lt; .001). Discussion Sleep impairments were associated with increased prevalence of psychotic-like experiences, and with more severe distress as caused by hallucinations. Sleep restoration should be explored as a first line intervention for people suffering from psychotic-like experiences. In case of delusions, such interventions should be directed at decreasing the number of nightly disturbances, while for individuals suffering from hallucinations additional focus should be put on increasing the achieved hours of sleep.


2021 ◽  
Vol 10 (2) ◽  
pp. 215-220
Author(s):  
Claudio Marcio Rodrigues Santana Junior ◽  
Victor Augusto Alves Bento ◽  
Edilson José Zafalon ◽  
Maria Cristina Mesquita ◽  
Daisilene Baena Castillo

Objective: To evaluate the quality of life and the impact of pain in patients with Temporomandibular Disorder (TMD) Muscle/joint TMJ of a public institution in Brazil. Methods: The study consisted of two stages: the first step was the application of the Ohip-14 questionnaires, Fonseca's Anamnestic Questionnaire and the McGill Questinionaire (Br-MPQ). In the next step, after the clinical treatment, only the Ohip-14 questionnaire was applied to compare the results after the treatment. The significance level was set at α = 0,05. Results: Overall, 100 individuals were examined and diagnosis with TMD Muscle/joint TMJ. The score OHIP-14 scale before the treatment was 30.02 ± 1.26 (mean ± standard error of the mean) points, being that after treatment it was 8.94 ± 0.63 points, statistically significant (p<0,001). The mean score in the Fonseca scale was 73.25 ± 1.93 points. Regarding the Br-MPQ, the results showed that TMD pain affects the patient in the area of work, leisure, home activities, family relationships, relationships with friends, sleep and appetite. Conclusion: SERDOF-DTM patients had severe TMD with a negative impact on quality of life, directly affecting their daily activities. The treatment proved to be effective in improving this condition.


2020 ◽  
Author(s):  
Fandresena Arilala Sendrasoa ◽  
Ratovonjanahary Volatantely ◽  
Razanakoto Naina Harinjara ◽  
Raharolahy Onivola ◽  
Rakotoarisaona Mendrika Fifaliana ◽  
...  

Abstract BACKGROUND: Psoriasis is a chronic, inflammatory and multifactorial dermatosis that impairs quality of life (QoL). Health-related QoL has become an important element in medical decision making along with the effectiveness and the harmlessness of the treatments.OBJECTIVE: To assess the impact of psoriasis in the QoL of patients with psoriasis by using the DLQI scales.METHODS: A cross-sectional study, during ten months, was conducted in the Department of Dermatology of the University Hospital Joseph Raseta Befelatanana Antananarivo Madagascar including patients more than 15 years-old with moderate to severe psoriasis. The severity of psoriasis was assessed using the “Psoriasis Area and Severity Index (PASI)”. QoL of patients with psoriasis was evaluated by using the DLQI scales.RESULTS: 80 patients were included, their mean age was 36.52 years and the male to female was 1.5:1. The mean DLQI score was 13.85. Symptoms, feelings and psychic were the most altered dimensions. QoL was impaired in young patients, single, having medium level education. Even though patients with disease duration more than 5 years had higher DLQI score than other patients, the difference was not statistically significant (p=0.36). Furthermore, clinical presentation of psoriasis didn’t influence patient’s QoL (p=0.73). Patients with nail involvement had QoL impaired but the difference with another localization was not statistically significant (p=0.2).The quality of life was influenced by body area involved. The higher the body surface area involved, the more QoL is impaired (p=0.002). Furthermore, the higher the PASI, the more QoL is altered (p=0.002).CONCLUSION: Psoriasis has a negative impact in the quality of life in Malagasy patients with psoriasis, especially in younger and single patients. Worse quality of life is correlated to severity of psoriasis.


2021 ◽  
Vol 1 ◽  
pp. 1531-1535
Author(s):  
Indah Nurfazriah ◽  
Ayu Fitriani

AbstractThe quality of sleep in pregnant women is very important for the health of both mother and fetus. The cause of sleep disturbances in pregnant women is due to the increased weight of the fetus, shortness of breath, fetal movement and back pain. To overcome this, it is necessary to do pregnancy exercises that increase the comfort of pregnant women. The purpose of this article is to determine the effect of pregnancy exercise on the quality of sleep of tird trimester pregnant women. The method used is a literature review which tries to dig up information about the effect of pregnancy exercise on the quality of sleep of pregnant women. Sources for conducting this literature review include systematic search studies of computerized databases (Scopus and Google Scholar) in the form of research journals totaling 3 journals. Writing scientific articles using the American Psychological Association bibliography (APA Format 6th Ed). The results showed that the mean value of sleep quality for pregnant women before doing pregnancy exercise was 12.43 and the mean value after pregnancy exercise was 6.43 (p = 0.000), thus there was an effect of pregnancy exercise on the sleep quality of pregnant women in the third trimester. The conclusion is based on the above review that pregnancy exercise can be an effort that can be done to improve the quality of sleep in pregnant womenKeywords: Pregnant Women, Sleep Quality, Pregnant Exercise AbstrakKualitas tidur pada ibu hamil sangat penting untuk kesehatan ibu dan janin. Penyebab gangguan tidur ibu hamil karena bertambahnya berat janin, sesak nafas, pergerakan janin dan nyeri punggung. Untuk mengatasi hal tersebut diperlukan senam hamil yang meningkatkan kenyamanan pada ibu hamil.Tujuan artikel ini untuk mengetahui pengaruh senam hamil terhadap kualitas tidur ibu hamil trimester III. Metode yang digunakan adalah studi tinjauan literatur (literature review) yang mencoba menggali informasi mengenai pengaruh senam hamil terhadap kualitas tidur ibu hamil. Hasil penelitian menunjukan bahwa nilai mean kualitas tidur ibu hamil sebelum melakukan senam hamil adalah 12.43 dan nilai mean setelah pemberian senam hamil 6.43(p= 0.000),dengan demikian ada pengaruh senam hamil terhadap kualitas tidur ibu hamil trimester III. Simpulan berdasarkan ulasan di atas bahwa aktivitas senam hamil dapat menjadi salah satu upaya yang dapat dilakukan untuk meningkatkan kualitas tidur pada ibu hamil.Kata kunci: Ibu hamil; Kualitas tidur; Senam hamil


Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2252
Author(s):  
Ahmad Salman ◽  
Kennedy Ouma Sigodo ◽  
Fatima Al-Ghadban ◽  
Badreya Al-Lahou ◽  
Maha Alnashmi ◽  
...  

The Coronavirus disease (COVID-19) pandemic has brought about drastic measures that have significantly altered the norms of daily living. These measures have affected human behaviors in disparate ways. This study seeks to understand the impact of the pandemic on physical activity and dietary behavior among adults living in Kuwait. A cross-sectional survey was conducted between 18 June and 15 July 2020, using a questionnaire disseminated through social media, including WhatsApp and Facebook. The target population was individuals aged 21 years or older living in the State of Kuwait. The study included 679 respondents; 57.9% were females, and 67.7% were Kuwaiti nationals. Both genders reported an increased consumption of vegetables, fruits, and carbohydrates, and a decreased consumption of fish and sugary drinks. Compared to males, females reported eating more during the outbreak than their pre-pandemic eating behaviors (32.3% vs. 35.9%, p < 0.05). Approximately one-third of respondents (33.1%) reported performing less than 30 min of physical activity or exercise in a week, and 36.4% of respondents rated their quality of sleep as ‘poor’ or ‘very poor’. The rate of smoking cigarettes among males was significantly higher than in females (40.6% vs. 5.3%, p < 0.001). Physical activity was positively correlated with vegetable consumption and quality of sleep. Quality of sleep was negatively correlated with the consumption of sweets and snacks, just as the consumption of vegetables was negatively correlated with the consumption of sugary drinks. The overall negative impact of the COVID-19 pandemic in Kuwait necessitates the development of health promotion interventions to support positive physical activity and dietary behaviors using alternative coping strategies among the residents of Kuwait.


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