The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin

2007 ◽  
Vol 45 (2) ◽  
pp. 286-295 ◽  
Author(s):  
Rose Hayeshi ◽  
Isaac Mutingwende ◽  
William Mavengere ◽  
Vimbai Masiyanise ◽  
Stanley Mukanganyama
2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Ayed S. Amr ◽  
Mousa N. Ahmad ◽  
Jalal A. Zahra ◽  
Mai A. Abdullah

Tannins are natural polyphenolic compounds widely distributed in the plant kingdom in the leaves, bark, fruits, and other parts. They have various biological functions in humans and animals and are used mainly in the pharmaceutical and cosmetic industries. The aim of this work was to isolate, extract, purify, and identify the tannins from the root bark of a common oak tree (Quercus aegilops L.) in Jordan and around the Mediterranean. The results showed that at least one form of ellagitannin (ellagic acid ester), quercitrin, afzelechin, valoneic acid, trigalloyl glucose, and catechin was identified in addition to two unidentified compounds. Results of this work can help in developing an ESI MS/MS search library for the constituents of the tannins of oak (Quercus aegilops L.) root bark.


Food Research ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 343-348
Author(s):  
M.M. Ali ◽  
K.S. Ahmed ◽  
H. Hossain ◽  
B. Roy ◽  
B. Rokeya ◽  
...  

Jute leaves (Corchorus spp.) have been used as a medicinal plant for the treatment of various diseases. The study was investigated on the antioxidant activities and HPLC profiling of polyphenolic compounds in ethanol extract of Corchorus olitorius (C. olitorius) and Corchorus capsularis (C. capsularis) leaves. The total antioxidant capacity was evaluated by phosphomolybdenum method and Identification and quantification of polyphenolic compounds were performed using HPLC-DAD system. The results indicated that eight polyphenolic compounds were found in the C. capsularis leaves but C. olitorius leaves contain six polyphenolic compounds. In fact, major identified polyphenolic compounds of C. capsularis leaves were caffeic acid (CA), 55.93±0.13; trans-ferulic acid (FA), 58.02±0.18; rutin hydrate (RH), 32.16±0.08; ellagic acid (EA), 53.65±0.11 and quercetin hydrate (QU), 46.17±0.09 mg/100 g of dry extract respectively. Whereas in C. olitorius leaves which were rutin hydrate (RH), 152.17±0.51; ellagic acid (EA), 143.27±0.58 and quercetin hydrate (QU), 292.83±0.73 mg/100 g of dry extract respectively. The results showed that C. capsularis leaves contained high level of total antioxidant capacity (214.32±1.95 mg of ascorbic acid/g of dry extract) than that of C. olitorius (165.66±1.30 mg of ascorbic acid/g of dry extract) leaves. The overall data suggested that C. olitorius and C. capsularis leaves contain a significant amount of several polyphenolic compounds that could be used as a natural antioxidant for functional foods.


2019 ◽  
Vol 18 (5) ◽  
pp. 131-140 ◽  
Author(s):  
Katarzyna Karczmarz ◽  
Agnieszka Szmagara ◽  
Elżbieta Anna Stefaniak

Ellagic acid (EA) is a natural antioxidant, belonging to the group of polyphenolic compounds. It displays a broad spectrum of pro-health effects, ranging from the prevention of cancer to antiviral properties. It is present in many fruit from the rose family (Rosaceae): strawberries, raspberries, blackberries and walnuts as well as cranberries and grapes. The available literature states that the fruit of roses, in addition to their aesthetic and functional applications, also show therapeutic properties, which, among other things, are associated with a high content of polyphenols, including ellagic acid derivatives. The aim of this research was to determine the differences in the content of free ellagic acid in the fruit of selected rose species. The test material consisted of freeze-dried sublimation and ground fruit from the following species of roses: R. canina, R. moyesii, R. pendulina. The fruit was separated into two fractions: flesh and seeds. Quantitative analysis of free ellagic acid was carried out by spectrofluorimetry. The free EA was present both in the flesh and in the seeds of the studied species of roses. Its content in the mentioned fractions varied depending on the species. The flesh of R. pendulina was characterised by the highest level of EA in free form (247.72 μg·g–1 of dry weight). The seeds of R. moyesii proved to be the most abundant in free EA (105.69 μg·g–1 of dry weight.


Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
D Sohretoglu ◽  
S Atasayar Sabuncuoglu ◽  
MK Sakar ◽  
H Ozgunes ◽  
O Sterner

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
A Lavaud ◽  
R Soletti ◽  
P Richomme ◽  
R Andriantsitohaina ◽  
D Guilet

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