Triterpenoids and iridoids from Patrinia scabiosaefolia

Fitoterapia ◽  
2017 ◽  
Vol 119 ◽  
pp. 130-135 ◽  
Author(s):  
Zhen-Hua Liu ◽  
Rui-Jing Ma ◽  
Liu Yang ◽  
Jin-Yu Li ◽  
Bo Hou ◽  
...  
Keyword(s):  
Patrinia Scabiosaefolia

Phytochemical and Pharmacological Review on Two Herbs of Baijiangcao: Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss

2020 ◽  
Vol 17 (5) ◽  
pp. 496-517
Author(s):  
Yangcheng Liu ◽  
Wei Liu ◽  
Jiaqi Wang ◽  
Yang Liu ◽  
Changlan Chen ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Volatile Components ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Comprehensive Review ◽  
Scientific Databases ◽  
The Past ◽  
Current State ◽  
Patrinia Scabiosaefolia ◽  
Antiviral Activities

Patrinia scabiosaefolia Fisch. Trev. and Patrinia villosa (Thunb.) Juss, are two species of Patrinia recorded in the Chinese Pharmacopoeia with the same Chinese name “Baijiangcao” and similar therapeutic effect in traditional Chinese medicine. The present article is the first comprehensive review on the chemical composition and pharmacological activities of these herbs. In this review, data on chemical constituents and pharmacological profile of the two herbs are provided. This review discusses all the classes of the 223 compounds (phenylpropanoids, flavonoids, terpenes, saponins and volatile components, etc.) detected in the two herbs providing information on the current state of knowledge of the phytochemicals present in them. In the past three years, our research group has isolated and identified about more than 100 ingredients from the two herbs. Therefore, we published a systematic review of our research papers and studies on the two herbs were carried out using resources such as classic books about Chinese herbal medicine and scientific databases including Pubmed, Web of Science, SciFinder, CNKI. etc. The present review discusses the most thoroughly studied pharmacological activities (antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, antitumor and antiviral activities) of the two herbs. This comprehensive review will be informative for scientists searching for new properties of these herbs and will be important and significant for the discovery of bioactive compounds from the two herbs and in complete utilization of Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss.

scholarly journals Patrinia scabiosaefolia inhibits the proliferation of colorectal cancer in vitro and in vivo via G1/S cell cycle arrest

2014 ◽  
Vol 33 (2) ◽  
pp. 856-860 ◽  
Author(s):  
MINGYUE ZHANG ◽  
GUODONG SUN ◽  
ALING SHEN ◽  
LIYA LIU ◽  
JINGZHEN DING ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Cycle Arrest ◽  
Patrinia Scabiosaefolia

Effects and mechanisms of iridoid glycosides from Patrinia scabiosaefolia on improving insulin resistance in 3T3-L1 adipocytes

2019 ◽  
Vol 134 ◽  
pp. 110806 ◽  
Author(s):  
Zhenhua Liu ◽  
Lanting Xu ◽  
Xiaoqing Xu ◽  
Yun Niu ◽  
FatmaS.A. Saadeldeen ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Iridoid Glycosides ◽  
Patrinia Scabiosaefolia

New triterpenoid saponins from Patrinia scabiosaefolia

2011 ◽  
Vol 346 (18) ◽  
pp. 2881-2885 ◽  
Author(s):  
Liang Gao ◽  
Lin Zhang ◽  
Nan Li ◽  
Jiang-Yun Liu ◽  
Pei-lie Cai ◽  
...  
Keyword(s):  
Triterpenoid Saponins ◽  
Patrinia Scabiosaefolia

scholarly journals Patrinia scabiosaefolia inhibits colorectal cancer growth through suppression of tumor angiogenesis

2013 ◽  
Vol 30 (3) ◽  
pp. 1439-1443 ◽  
Author(s):  
LIWU CHEN ◽  
LIYA LIU ◽  
LING YE ◽  
ALING SHEN ◽  
YOUQIN CHEN ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Tumor Angiogenesis ◽  
Cancer Growth ◽  
Patrinia Scabiosaefolia

Anti-inflammatory effects of methanol extract of Patrinia scabiosaefolia in mice with ulcerative colitis

2011 ◽  
Vol 136 (3) ◽  
pp. 428-435 ◽  
Author(s):  
Eu-jin Cho ◽  
Ji-Sun Shin ◽  
Young-Su Noh ◽  
Young-Wuk Cho ◽  
Seung-Jae Hong ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Methanol Extract ◽  
Patrinia Scabiosaefolia ◽  
Anti Inflammatory

scholarly journals Metabolomic Study on the Preventive Effect ofPatrinia scabiosaefoliaFisch on Multipathogen Induced Pelvic Inflammatory Disease in Rats

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Wei Zou ◽  
Xiaoke Wen ◽  
Yi Zheng ◽  
Zuoqi Xiao ◽  
Jieying Luo ◽  
...  
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Genital Tract ◽  
Sugar Metabolism ◽  
Tca Cycle ◽  
Inflammatory Cells ◽  
Preventive Effect ◽  
Elevated Expression ◽  
Patrinia Scabiosaefolia ◽  
Metabolomic Study

Patrinia scabiosaefoliaFisch (PSF), a well-known traditional Chinese medicine (TCM), has been used as a “heat-clearing and detoxifying” agent. The present study was to illustrate the preventive effect of PSF on pelvic inflammatory disease (PID) in rats. The PID model was constructed by multipathogen infection of the upper genital tract with reference to the method previously reported. Urine metabolomic analysis was conducted with a GC-MS coupled with derivatization method. In this study, PID rats showed obvious infiltration of inflammatory cells and elevated expression of cytokines (IL-1βand IL-6) in upper genital tract, compared with control rats. Sixteen differentiating metabolites contributed to the alteration of metabolic profile in PID rats, including two amino acids, three fat acids, nine organic acids, and two types of sugars. The rats, infected by multipathogen and administered with PSF, showed decreased infiltration of inflammatory cells and lowered expression of cytokines in upper genital tract, compared with PID rats. Meanwhile, PSF intervened in the PID-associated alterations in TCA cycle, sugar metabolism, amino acid metabolism, and other uncertain metabolic pathways. These results indicate that PSF has preventive effect on multipathogen induced PID and holistic interventional effect on disease-associated metabolomic change.

scholarly journals Nine Unique Iridoids and Iridoid Glycosides From Patrinia scabiosaefolia

2021 ◽  
Vol 9 ◽  
Author(s):  
Zhenhua Liu ◽  
Yun Niu ◽  
Li Zhou ◽  
Lijun Meng ◽  
Sitan Chen ◽  
...  
Keyword(s):  
Spectroscopic Analysis ◽  
Chemical Constituents ◽  
Iridoid Glycosides ◽  
Chinese Herb ◽  
2D Nmr ◽  
Iridoid Glycoside ◽  
Cytotoxic Activities ◽  
Medicinal Value ◽  
Patrinia Scabiosaefolia ◽  
Mcf 7

Patrinia scabiosaefolia is a medical and edible Chinese herb with high nutritional and medicinal value. The continuing study of its chemical constituents led to the discovery of nine unique iridoids and iridoid glycosides, including three new iridoids (1-3) and six previously unknown irioid glycosides (5-10), and one known compound (4). Among them, compound 1 was a deformed iridoid, while compounds 3, 5-7, and 10 formed a new ring in their skeletons which was uncommon in this genus. For compound 3, the new ring existed between C-3 and C-10, while a 1,3-dioxane appeared between C-7 and C-10 in compounds 5-7 and 10. Moreover, compound 10 was a bis-iridoid glycoside, which was the first reported in P. scabiosaefolia. And the sugar of irioid glycosides (5-10) was glucose at C-11, except in 9 which had a 5-deoxyglucose moiety. All their structures were confirmed based on the extensive spectroscopic analysis, including IR, UV, HR-ESI-MS, ECD, and 1D- and 2D-NMR experiments. Their cytotoxic activities against HL-60, A-549, SMMC-7721, MCF-7, SW480 were also tested.

scholarly journals Patrinoside, a new iridoid glycoside from Patrinia scabiosaefolia.

1974 ◽  
Vol 22 (8) ◽  
pp. 1935-1937 ◽  
Author(s):  
HEIHACHIRO TAGUCHI ◽  
TOHRU ENDO
Keyword(s):  
Iridoid Glycoside ◽  
Patrinia Scabiosaefolia
Sign in / Sign up

Export Citation Format

Share Document