Evaluation of coagulation abnormalities among women with vaginal bleeding in the first trimester of pregnancy

2012 ◽  
Vol 118 (3) ◽  
pp. 202-204 ◽  
Author(s):  
Vilma Kovač ◽  
Veljko Vlaisavljević ◽  
Milan Reljič
Keyword(s):  
Vaginal Bleeding ◽  
First Trimester ◽  
Coagulation Abnormalities ◽  
First Trimester Of Pregnancy

scholarly journals Patterns and Predictors of Vaginal Bleeding in the First Trimester of Pregnancy

2010 ◽  
Vol 20 (7) ◽  
pp. 524-531 ◽  
Author(s):  
Reem Hasan ◽  
Donna D. Baird ◽  
Amy H. Herring ◽  
Andrew F. Olshan ◽  
Michele L. Jonsson Funk ◽  
...  
Keyword(s):  
Vaginal Bleeding ◽  
First Trimester ◽  
First Trimester Of Pregnancy

scholarly journals NICE guideline “Ectopic pregnancy and miscarriage”: new changes and importance for the clinicist

2021 ◽  
pp. 48-52
Author(s):  
- -
Keyword(s):  
Ectopic Pregnancy ◽  
Clinical Guidelines ◽  
Vaginal Bleeding ◽  
Recurrent Miscarriage ◽  
First Trimester ◽  
Current Data ◽  
Nice Guideline ◽  
Threatened Miscarriage ◽  
Patients At Risk ◽  
First Trimester Of Pregnancy

The purpose of this publication is to summarize the current data on the effectiveness of progestogens in patients with threatened miscarriage (vaginal bleeding in the first trimester of pregnancy) and to review the updated UK National Institute for Health and Care Excel (NICE) clinical guidelines on ectopic pregnancy and miscarriage.In accordance with the opinion of the Cochrane Society experts and the updated NICE clinical guidelines for 2021, vaginal progesterone at a dose of 800 mg/day is the only intervention that has been shown to be effective in increasing live births compared to placebo for women with one or more previous miscarriages and early vaginal bleeding (relative risk 1.08, 95% confidence interval 1.02–1.15, high certainty evidence). Upon confirmation of fetal heartbeat, this treatment should be extended until 16 weeks of gestation.There is still uncertainty over the effectiveness and safety of alternative progestogen treatments (as dydrogesterone) for threatened and recurrent miscarriage. There is also no evidence of benefit of any other preparations or doses of progesterone in patients at risk of miscarriage.

Pelvic Pain and/or Vaginal Bleeding in the First Trimester of Pregnancy

1999 ◽  
Vol 6 (6) ◽  
pp. 283-294
Author(s):  
MARIBEL U. LOCKWOOD ◽  
FRANZ E. VELARDE ◽  
JOSEPH CERNIGLIARO
Keyword(s):  
Pelvic Pain ◽  
Vaginal Bleeding ◽  
First Trimester ◽  
First Trimester Of Pregnancy

scholarly journals ASSESSMENT OF VAGINAL BLEEDING IN FIRST TRIMESTER OF PREGNANCY BY COMPARATIVE STUDY OF CLINICAL AND ULTRASONOGRAPHIC EVALUATION

2019 ◽  
Vol 3 (12) ◽  
Author(s):  
Aakarsh Sinha ◽  
Kumar Amit
Keyword(s):  
Comparative Study ◽  
Vaginal Bleeding ◽  
First Trimester ◽  
Abnormal Pregnancy ◽  
Medical College ◽  
Non Invasive ◽  
First Trimester Pregnancy ◽  
Obstetrics And Gynaecology ◽  
History Of ◽  
First Trimester Of Pregnancy

Bleeding per vaginum in the first trimester of pregnancy is one of the most common obstetric problems. Bleeding in early pregnancy is an indicator of an abnormality interrupting the normal development and is a common cause of hospital admission. If the viability or non viability of pregnancy can be made on USG, then hormonal therapy and hospitalization can be avoided. This is usually impossible with history and clinical examination and can be established only by USG. Hence based on above findings the present study was planned for Assessment of Vaginal Bleeding in First Trimester of Pregnancy by Comparative Study of Clinical and Ultrasonographic Evaluation. The present study was planned in Department of Obstetrics and Gynaecology, Madhubani Medical College and Hospital, Madhubani, Bihar. In the present study 30 females having history of bleeding per vaginum in the first trimester of pregnancy were enrolled. The data generated from the present study concludes that USG is an extremely valuable non invasive tool in the identifying the causes of first trimester vaginal bleeding. It is also helpful in the decision-making algorithm about the safe continuation of the pregnancy and timely intervention for abnormal pregnancy. High incongruity was seen in our study between clinical diagnosis and USG diagnosis. Keywords: Vaginal Bleeding, First Trimester, Pregnancy, Clinical, Ultrasonographic Evaluation, etc.

scholarly journals Pregnancy outcome in women presenting with per vaginal bleeding in first trimester of pregnancy

2021 ◽  
Vol 10 (2) ◽  
pp. 439
Author(s):  
Aisha Moon ◽  
Saima Shabbir
Keyword(s):  
Vaginal Bleeding ◽  
Placenta Previa ◽  
Tertiary Care ◽  
First Trimester ◽  
Fetal Outcome ◽  
Care Hospital ◽  
Wide Range ◽  
Life Threatening ◽  
Red Flag ◽  
First Trimester Of Pregnancy

Background: Approximately 16%-25% of pregnancies are complicated by first trimester bleeding. The wide range of causes of early pregnancy bleeding, threat to loss the pregnancy and fear of having any life threatening cause puts pregnant female with first trimester bleeding into the state of uncertainty which leads to anxiety and depression. The objective of this study was to determine fetal outcome in women presenting with per vaginal bleeding in first trimester of pregnancy.Methods: This prospective observational study was carried out on 75 women presenting with complain of first trimester bleeding at Kulsumbai Valika hospital, a tertiary care hospital located in SITE area Karachi, Pakistan from July 2019 to July 2020 for a period of 1 year. A Performa was designed to collect information and patient followed until pregnancy is terminated.Results: The majority of participants presented at 8th week of gestation. Out of 75 participants who presented with first trimester bleeding 40% ended up in miscarriage. 6% had ectopic, 2% had molar pregnancy, 4% had placenta previa, 6% had preterm birth and 40% had healthy infant at the end of pregnancy.Conclusions: Bleeding in pregnancy is a red flag sign and needs to be addressed with wise approach to have optimal possible maternal and fetal outcomes.

scholarly journals Ultrasonographic evaluation of first trimester bleeding

2017 ◽  
Vol 6 (8) ◽  
pp. 3614
Author(s):  
Awdhut Tiparse ◽  
Birwa Gandhi ◽  
Arpita Patel
Keyword(s):  
Clinical Diagnosis ◽  
Vaginal Bleeding ◽  
First Trimester ◽  
Diagnostic Process ◽  
Life Threatening ◽  
Threatened Abortion ◽  
First Trimester Of Pregnancy ◽  
General Physical ◽  
A Prospective Study ◽  
Maternity Home

Background: Vaginal bleeding in the first trimester is a common obstetric situation ranging from an insignificant episode to life threatening emergency. The major causes are abortion, ectopic, and molar pregnancy. Ultrasonography is playing an increasing role in the diagnostic process. This study was taken up to evaluate its utility vis-à-vis clinical examination findings.Methods: A Prospective study was carried out on all inpatients admitted to Gopnath Maternity Home, Sir T. Hospital, Bhavnagar with complaints of bleeding per vaginum in the first trimester of pregnancy during the study period from December 2016 to May 2017. A complete general physical and pelvic examination was done to arrive at a clinical diagnosis. Patients were then subjected to ultrasound examination. Clinical diagnosis and ultrasound diagnosis were correlated.Results: Among these 200 cases, threatened abortion was the commonest cause of bleeding. This was observed in 74 cases (37%). There were 40 (20%) cases of missed abortion in the present study. Incomplete abortion and complete abortion in 14 and 6 cases respectively. There were 26 (13%) cases of ectopic pregnancy.Conclusions: Ultrasound is a valuable tool in the differentiation of causes of first trimester vaginal bleeding. Ultrasound is helpful in the decision-making algorithm about the safe continuation of the pregnancy, timely intervention for abnormal pregnancy.

FRACTIONAL DETERMINATIONS OF URINARY 17-KETOSTEROIDS IN HYPEREMESIS GRAVIDARUM

1962 ◽  
Vol 41 (1) ◽  
pp. 123-128 ◽  
Author(s):  
Pentti A. Järvinen ◽  
Sykkö Pesonen ◽  
Pirkko Väänänen
Keyword(s):  
Hyperemesis Gravidarum ◽  
First Trimester ◽  
Control Group ◽  
Before And After ◽  
Daily Urine ◽  
First Trimester Of Pregnancy ◽  
The Difference

ABSTRACT The fractional determination of 17-ketosteroids in the daily urine was performed in nine cases of hyperemesis gravidarum and in four control cases, in the first trimester of pregnancy both before and after corticotrophin administration. The excretion of total 17-KS is similar in the two groups. Only in the hyperemesis group does the excretion of total 17-KS increase significantly after corticotrophin administration. The fractional determination reveals no difference between the two groups of patients with regard to the values of the fractions U (unidentified 17-KS), A (androsterone) and Rest (11-oxygenated 17-KS). The excretion of dehydroepiandrosterone is significantly higher in the hyperemesis group than in the control group. The excretion of androstanolone seems to be lower in the hyperemesis group than in the control group, but the difference is not statistically significant. The differences in the correlation between dehydroepiandrosterone and androstanolone in the two groups is significant. The high excretion of dehydroepiandrosterone and low excretion of androstanolone in cases of hyperemesis gravidarum is a sign of adrenal dysfunction.

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