scholarly journals Pregnancy outcome in women presenting with per vaginal bleeding in first trimester of pregnancy

2021 ◽  
Vol 10 (2) ◽  
pp. 439
Author(s):  
Aisha Moon ◽  
Saima Shabbir
Keyword(s):  
Vaginal Bleeding ◽  
Placenta Previa ◽  
Tertiary Care ◽  
First Trimester ◽  
Fetal Outcome ◽  
Care Hospital ◽  
Wide Range ◽  
Life Threatening ◽  
Red Flag ◽  
First Trimester Of Pregnancy

Background: Approximately 16%-25% of pregnancies are complicated by first trimester bleeding. The wide range of causes of early pregnancy bleeding, threat to loss the pregnancy and fear of having any life threatening cause puts pregnant female with first trimester bleeding into the state of uncertainty which leads to anxiety and depression. The objective of this study was to determine fetal outcome in women presenting with per vaginal bleeding in first trimester of pregnancy.Methods: This prospective observational study was carried out on 75 women presenting with complain of first trimester bleeding at Kulsumbai Valika hospital, a tertiary care hospital located in SITE area Karachi, Pakistan from July 2019 to July 2020 for a period of 1 year. A Performa was designed to collect information and patient followed until pregnancy is terminated.Results: The majority of participants presented at 8th week of gestation. Out of 75 participants who presented with first trimester bleeding 40% ended up in miscarriage. 6% had ectopic, 2% had molar pregnancy, 4% had placenta previa, 6% had preterm birth and 40% had healthy infant at the end of pregnancy.Conclusions: Bleeding in pregnancy is a red flag sign and needs to be addressed with wise approach to have optimal possible maternal and fetal outcomes.

scholarly journals Study of maternal and fetal outcome in various types of placenta previa

2018 ◽  
Vol 7 (11) ◽  
pp. 4652
Author(s):  
Sonal Bhuyar ◽  
Neha Dharmale
Keyword(s):  
Neonatal Outcome ◽  
Tertiary Care Hospital ◽  
Placenta Previa ◽  
Tertiary Care ◽  
Fetal Outcome ◽  
Intrauterine Death ◽  
Care Hospital ◽  
Institutional Deliveries ◽  
Life Threatening ◽  
A Prospective Study

Background: Placenta previa is one of the life-threatening complications in obstetrics which affects maternal and neonatal outcome. Now-a-days its incidence is increasing due to previous operative procedures. The objective of the present study was to study out maternal and fetal outcome in various types of placenta previa.Methods: A prospective study was conducted in our tertiary care hospital on 78 patients in order to know the cause and outcome of placenta previa.Results: Early termination was carried out in major PP group due to APH. 13 out of 17 patients presenting with APH had major degree of PP. Abnormal lie and presentation are commonly seen in cases of PP however cephalic constituted 83.3% cases of fetal presentations in present study followed by breech 10.2%, oblique 3.9%, face 1.3% and transverse 1.3%. In this study, 92.2% neonates were born alive while neonatal death and intrauterine death (IUD) was observed in 5.2% and 2.6% neonates respectively.Conclusions: Combined efforts for prevention of risk factors for PP, timely diagnosis and planned institutional deliveries can only reduce the morbidity and mortality associated with PP.

ANTIBIOTIC SUSCEPTIBILITY PATTERN OF STAPHYLOCOCCOUS AUREUS ISOLATED FROM VARIOUS CLINICAL SPECIMENS OF TERTIARY CARE HOSPITAL IN TIRUPATI.

2021 ◽  
pp. 14-15
Author(s):  
Indira Ananthapadmanab asamy ◽  
V. Pavani Sai Mounika ◽  
K. Vijayakumar ◽  
C.H. Srinivasa Rao
Keyword(s):  
Antimicrobial Susceptibility ◽  
Tertiary Care ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Clinical Specimens ◽  
Antimicrobial Susceptibility Pattern ◽  
Wide Range ◽  
Life Threatening ◽  
Mrsa Infection ◽  
Systemic Infections

INTRODUCTION: Staphylococcus aureus causes a wide range of infections including skin and soft tissue infections to life-threatening systemic infections like sepsis, endocarditis. This study ais to evaluate the antimicrobial susceptibility pattern of S.aurues among various clinical specimens. METHODS: The study included 326 S.aurues, isolated from various clinical specimens which were subjected to antimicrobial susceptibility testing as per CLSI guidelines. RESULTS: Among the 326 isolates, the highest were from pus specimens (47.85%), and was from Orthopaedics department (28.53%). Among the isolates, 219 (67.17%) were Methicilin resistant. All isolates were sensitive to Vancomycin, and all urine isolates were sensitive to Nitrofurantoin. The highest resistance was towards Penicillin (87.42%), Erythromycin (85.28), and Ciprooxacin (83.13%). CONCLUSION: The most effective way to prevent MRSA infection in every hospital is by performing continuous surveillance of antibiotic resistance and by following an effetive antibiotic policy.

scholarly journals Thyroid dysfunction among Indian pregnant women and its effect on the maternal and fetal outcome

2021 ◽  
Vol 10 (3) ◽  
pp. 893
Author(s):  
Aditi Jain ◽  
Raksha M. ◽  
Kanakalatha D. Nakum
Keyword(s):  
Early Pregnancy ◽  
Tertiary Care ◽  
First Trimester ◽  
Antenatal Clinic ◽  
Fetal Outcome ◽  
Overt Hypothyroidism ◽  
Thyroid Disorders ◽  
Care Hospital ◽  
Thyroid Disorder

Background: Screening of thyroid disorders in antenatal women during first trimester, to recommend management of thyroid disorder during pregnancy and to know the maternal and fetal outcome of such pregnancy.Methods: This is a prospective study for the incidence of thyroid disorder in early pregnancy and the outcome of such pregnancy. 100 cases were randomly selected from the antenatal clinic at a tertiary care hospital in India and after fulfilling the inclusion criteria they were subjected to screening for thyroid disorder till 13 weeks of pregnancy. TSH is often considered the “gold standard” for assessing thyroid function. If the participant had normal value then she was not subjected to follow up, but if abnormal, then follow up was done after 4-8 weeks, thyroid profile was repeated and if values were altered, they were medically managed and closely monitored. The obstetric and perinatal outcome of the pregnancy was noted.Results: In this screening study to detect and manage thyroid disorder, 100 antenatal women were selected randomly, from which 49 women where primigravidae and 51 women were multi-gravidae, 17 of them were of <20years, 54 were between 21 to 25 years. There was 5 percent incidence of thyroid disorder in the study group. There were 3 cases of hyperthyroidism and 2 cases of overt hypothyroidism which had poor fetal and maternal outcome on follow up.Conclusions: Our study shows that the evaluation of thyroid disorders in early pregnancy and timely intervention will lead to a decrease in the complications thereby improving the maternal and fetal outcome.

scholarly journals Maternal and fetal outcome in placenta previa: our experience

2020 ◽  
Vol 9 (8) ◽  
pp. 3253
Author(s):  
G. D. Maiti ◽  
M. Adhikary ◽  
P. R. Lele ◽  
Shilpa Gupta ◽  
M. Saha ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Placenta Previa ◽  
Tertiary Care ◽  
Neonatal Morbidity ◽  
Fetal Outcome ◽  
Blood Component ◽  
Care Hospital ◽  
Potential Risks ◽  
Risks Factors

Background: Placenta previa contributes substantial maternal and neonatal morbidity including management challenges for obstetrician. This study was to evaluate the potential risks factors and feto-maternal, outcome in placenta previa. This study was done with the intent of developing insight into risk factors, clinical presentation, various interventions and management for overall improvement in maternal and fetal outcome in placenta previa.Methods: A prospective observational study, where 30 cases of placenta previa confirmed after 28 weeks POG, treated in a public sector tertiary care hospital from June 2016 to June 2018 were included. Authors analyzed the data to evaluate the potential risks factors and maternal and fetal outcome in placenta previa.Results: In this study, major contributing risk factors for placenta previa were associated with multiparity (76.7%), maternal age >30 in 50%, previous LSCS in 46.7%, repeated uterine procedure like suction evacuation/curretage. There was a high rate of maternal morbidity mainly due to haemorrhage. Perioperative uterine artery embolization (UAE) in 3 (10%), intra-operative procedures namely devascularization, internal iliac ligation in 66.6% cases, peripartum hysterectomy in 2 (6.66%) were done to control haemorrhage. Blood and blood products transfusion required in 26.7% of cases. Fetal morbidity included prematurity in 9 (33.3%), NICU admission in 11 (36.6%) majority of which included 8 (26.7%) babies of birth weight <2000 grams.Conclusions: Placenta previa contributes to significant maternal and neonatal morbidity. Multiparity, post LSCS pregnancy constitute major factor for placenta previa. Management requires high-risk obstetrical care with frequent antenatal visits. Serial ultrasonography in reported cases of low-lying placenta to mandatory exclude overdiagnosis or migration. All cases of placenta previa need to be managed in a higher centre facility of blood component therapy and neonatal intensive care unit. Prematurity and low birth weight remain a significant cause for neonatal morbidity.

scholarly journals Prevalence of Dengue, Chikungunya, and Zika Viruses in Febrile Pregnant Women: An Observational Study at a Tertiary Care Hospital in North India

2021 ◽  
Author(s):  
Akanksha Gupta ◽  
Parul Jain ◽  
Vimala Venkatesh ◽  
Anjoo Agarwal ◽  
D. Himanshu Reddy ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Rural Areas ◽  
Vaginal Bleeding ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Fetal Outcome ◽  
North India ◽  
Care Hospital ◽  
Delivery Outcome ◽  
The Difference

Dengue virus (DENV), chikungunya virus (CHIKV), and Zika virus (ZIKV) are arboviruses that can affect maternal and fetal outcome if acquired during pregnancy. This study was done to estimate the positivity of DENV, CHIKV, and ZIKV in febrile pregnant women attending a tertiary care hospital in north India. Symptomatic pregnant women were tested for these viruses by IgM ELISA and/or by Trioplex real-time polymerase chain reaction. Their symptoms and laboratory parameters were recorded and were followed up till delivery to know their immediate delivery outcome. Of 104 women tested, 50 (48.1%) were positive for viral markers. Of these, evidence of infection by DENV, CHIKV, and both was found in 34 (32.7%), 10 (9.6%), and 6 (5.8%), respectively. ZIKV was not detected in any woman. Maximum DENV positivity occurred in the third trimester of pregnancy and in women residing in urban than rural areas. Chills and rigors, arthralgia, retro-orbital pain, anemia, and vaginal bleeding were more commonly associated with DENV positivity. Backache, arthralgia, jaundice, and vaginal bleeding were more common in CHIKV positives but the difference between positives and nonpositives regarding these symptoms was not statistically significant. Dengue infections were associated with more frequent hospitalizations (OR = 8.38, 95% confidence intervals [CI] = 3.29–21.30) and mortality (OR = 19.0, 95% CI = 1.01–357.10). Hence, to conclude, in India wherever possible, all symptomatic pregnant women should be screened for DENV, CHIKV, and ZIKV as part of sentinel surveillance for ZIKV.

scholarly journals The bleeding mother and her baby: a study to determine the fetomaternal outcome in cases of placenta previa

2020 ◽  
Vol 9 (9) ◽  
pp. 3775
Author(s):  
Preeti Frank Lewis ◽  
Sana Tarannum Bijapur ◽  
Deepika Gurnani
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Uterine Artery ◽  
Placenta Previa ◽  
Tertiary Care ◽  
Previous History ◽  
Fetal Outcome ◽  
Care Hospital ◽  
Artery Ligation ◽  
Uterine Artery Ligation

Background: Placenta previa is one of the major causes for obstetric hemorrhagic morbidity and mortality with increasing incidence in recent times. This study aims at determining risk factors, maternal and fetal outcome associated with placenta previa.Methods: This was an observational, retrospective study conducted at a tertiary care hospital in Mumbai from May 2017 to March 2020. A total of 102 women with placenta previa during the study period were included, their case records critically analyzed to identify risk factors, maternal outcome in relation with blood transfusion required, ICU admission, obstetric hysterectomy and fetal outcome pertaining to prematurity, asphyxia and mortality.Results: A total of 102 patients were analyzed. Placenta previa was more common in >26 years of age, multipara (64.7%), with previous history of caesarean sections (21.5%) and previous curettage (11.7%), 44.2% babies born were preterm, 4.4% stillbirths and 8.5% neonatal deaths. Maternal complications like antepartum hemorrhage was seen in 58.8% patients and postpartum hemorrhage in 33.3%, blood transfusion was required in only 18 patients post operatively, bladder rent was seen in 3 patients and there was no maternal mortality. 44 patients required uterine artery ligation, Ashok Anand stitch was taken in 37 patients, uterus compression sutures in 10, obstetric hysterectomy in 7 patients and internal iliac artery ligation in 2 patients.Conclusions: Early identification of women at risk, obstetric preparedness and simple techniques like uterine artery ligation, Ashok Anand stitch and uterine compression sutures can help in effectively reducing need for multiple blood transfusions and morbidity.

scholarly journals Maternal and Fetal Outcome in Eclampsia: A Study From Tertiary Care Hospital

2017 ◽  
Vol 15 (2) ◽  
pp. 6-9
Author(s):  
Husneyara Haque ◽  
Kalpana Kumari Thapa
Keyword(s):  
Early Recognition ◽  
Tertiary Care ◽  
Fetal Outcome ◽  
Morbidity And Mortality ◽  
Care Hospital ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Medical College ◽  
Life Threatening ◽  
Study Population

Introduction: Eclampsia is an acute and life-threatening complication of pregnancy associated with elevated maternal and fetal morbidity and mortality. This study was done with the aim to evaluate the maternal and fetal outcome in eclampsia patients and to observe various factors affecting its occurrence and outcome. Methods: A retrospective cross-sectional hospital based study carried out in Nepalgunj Medical College, Nepalgunj from January 2015 to December 2016. Details and data obtained from maternity register were analysed. All patients with eclampsia were included and fetomaternal outcomes measured in terms of complications. Simple descriptive statistical method was applied for analysis. Result: Out of 6056 pregnant women, 46 had eclampsia with the incidence of 7.59 per 1000 deliveries. 58.7% of study population belonged to age group of 21-30 years followed by 36.96% from age less than 20 years. 78.26% cases were unbooked. 73.91% eclamptic patients were primi gravida and 60.87% had gestational age less than 37 weeks. Half of pregnancies with eclampsia underwent ceasarian for delivery and 30.44% required ICU care. One third women developed eclampsia related complications and 2(4.35%) died. Common complications were atonic postpartum heamorrhage (15.21%), psychosis (8.71%) acute renal failure (4.35%). 60.86% newborn were preterm and 56.52% were low birth weight. In 50% newborn, Apgar score at 5 minutes was less than 7. Fetal death was 10.85%. Conclusion: Eclampsia continues to be one of the prime etiological factors for maternal and fetal morbidity and mortality. Therefore early recognition and proper management are vital to tackle this challenge.

Subclinical Hypothyroidism (SCH) in the First Trimester of Pregnancy: A Cross-Sectional Study at a Tertiary Care Hospital

2021 ◽  
Vol 15 (8) ◽  
pp. 1855-1857
Author(s):  
Israr-Ul- Haq ◽  
Junaid Mushtaq ◽  
Atiq Ahmad ◽  
Waqas Mahmood ◽  
Mujtaba Hasan Siddiqui ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Subclinical Hypothyroidism ◽  
Neonatal Death ◽  
Tertiary Care ◽  
First Trimester ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
First Trimester Of Pregnancy

Aim: To evaluate and assess the prevalence along with its related complications of subclinical hypothyroidism in pregnant ladies during the 1st trimester of pregnancy in Pakistani population. Study design: Cross sectional study Place and duration of study: Department of Medicine, Unit-1 of Lahore General Hospital, Lahore, Pakistan from 11th February 2019 to 29th December 2019. Methodology: Four hundred and fifty seven pregnant women with a gestational age up to 12th week with an age group between 18-45 years were included in this study. Blood samples were collected for free triiodothyronine, free thyroxine and thyroid stimulating hormone levels. Patients were regularly followed at an interval of 4 weeks for their entire pregnancy period. Adverse events and complications were noted. Results: One hundred and sixty nine subjects had TSH levels above the normal range i.e., 4.6-10mIU/L. 288 subjects were having TSH below 4 mIU/L levels. The overall prevalence of subclinical hypothyroidism (SCH) was found to be 37% in pregnant women during their first trimester of pregnancy. Pregnant women having subclinical hypothyroidism (SCH) were having higher risks of loss of pregnancy, abruptio placentae and neonatal death rates as compared to euthyroid pregnant women. Conclusion: Higher prevalence of subclinical hypothyroidism (SCH) in the first trimester of pregnancy indicates that these women are at increased risks of loss of pregnancy, placental abruption and neonatal death as compared to euthyroid pregnant women. Keywords: First trimester; pregnancy; subclinical hypothyroidism

scholarly journals A study on presentation and management of ectopic pregnancy at tertiary care hospital

2021 ◽  
Vol 10 (5) ◽  
pp. 1997
Author(s):  
Tarini Singh ◽  
Sanil Mohan ◽  
Shikha Aggarwal ◽  
Debkalyan Maji
Keyword(s):  
Ectopic Pregnancy ◽  
Tertiary Care ◽  
First Trimester ◽  
Severe Form ◽  
Successful Outcome ◽  
Care Hospital ◽  
Northern India ◽  
Pain Abdomen ◽  
Life Threatening ◽  
A Prospective Study

Background: Ectopic pregnancy and its consequences are the most severe form of obstetric emergency during first trimester of pregnancy. It is a kind of life threatening emergency leading to significant maternal morbidity and even mortality.Methods: A prospective study was conducted at a tertiary care teaching hospital of Northern India from 01 Jan 2020 to 31 Mar 2020. All cases of ectopic pregnancy which were admitted and managed during this study period were included in the study. All collected data were analysed with Epitable 6.04 version and SPSS version 20 software.Results: During the study period total 32 cases of ectopic pregnancy were studied. Classical symptoms of amenorrhoea, pain abdomen and bleeding per vaginum were observed in 62.50% cases whereas 93.75% cases were associated with pain abdomen only and 71.88% cases had the symptoms of bleeding per vaginum only. All cases were managed surgically. The incidence of ectopic pregnancy was one in 200 delivered pregnancy. Most case were multiparas and common in 27 -32 yr age group (53.13%). Tubal ectopic pregnancy was common in right side (63%).   Approximately 81% cases presented with haemoperitoneum and 63% cases required blood transfusion.Conclusions: Ectopic pregnancy mostly presents as an obstetrics emergency in our hospital especially with rupture ectopic pregnancy with haemoperitoneum. Early diagnosis and intervention suited best for the situation is mainstay for favourable and successful outcome.

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