Assessment of HBEC-5i endothelial cell line cultivated in astrocyte conditioned medium as a human blood-brain barrier model for ABC drug transport studies

Barrier Model ◽

Astrocyte Conditioned Medium

The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2008.05730.x ◽

2008 ◽

Vol 107 (5) ◽

pp. 1358-1368 ◽

Cited By ~ 176

Author(s):

Birk Poller ◽

Heike Gutmann ◽

Stephan Krähenbühl ◽

Babette Weksler ◽

Ignacio Romero ◽

...

Keyword(s):

Endothelial Cell ◽

Human Brain ◽

Cell Line ◽

Blood Brain Barrier ◽

Human Blood ◽

Drug Transport ◽

Brain Endothelial Cell ◽

Transport Studies ◽

Quantitative Targeted Absolute Proteomic Analysis of Transporters, Receptors and Junction Proteins for Validation of Human Cerebral Microvascular Endothelial Cell Line hCMEC/D3 as a Human Blood–Brain Barrier Model

Molecular Pharmaceutics ◽

10.1021/mp3004308 ◽

2012 ◽

Vol 10 (1) ◽

pp. 289-296 ◽

Cited By ~ 131

Author(s):

Sumio Ohtsuki ◽

Chiemi Ikeda ◽

Yasuo Uchida ◽

Yumi Sakamoto ◽

Florence Miller ◽

...

Keyword(s):

Endothelial Cell ◽

Cell Line ◽

Blood Brain Barrier ◽

Human Blood ◽

Proteomic Analysis ◽

Microvascular Endothelial Cell ◽

Endothelial Cell Line ◽

Barrier Model ◽

Junction Proteins

Generation of an Immortalized Murine Brain Microvascular Endothelial Cell Line as an In Vitro Blood Brain Barrier Model

Journal of Visualized Experiments ◽

10.3791/4022 ◽

2012 ◽

Cited By ~ 9

Author(s):

Malgorzata Burek ◽

Ellaine Salvador ◽

Carola Y. Förster

Keyword(s):

Endothelial Cell ◽

Cell Line ◽

Blood Brain Barrier ◽

Brain Barrier ◽

Microvascular Endothelial Cell ◽

Brain Microvascular Endothelial Cell ◽

Endothelial Cell Line ◽

Comparison of a Rat Primary Cell-Based Blood-Brain Barrier Model With Epithelial and Brain Endothelial Cell Lines: Gene Expression and Drug Transport

Frontiers in Molecular Neuroscience ◽

10.3389/fnmol.2018.00166 ◽

2018 ◽

Vol 11 ◽

Cited By ~ 28

Author(s):

Szilvia Veszelka ◽

András Tóth ◽

Fruzsina R. Walter ◽

Andrea E. Tóth ◽

Ilona Gróf ◽

...

Keyword(s):

Gene Expression ◽

Endothelial Cell ◽

Blood Brain Barrier ◽

Cell Lines ◽

Drug Transport ◽

Primary Cell ◽

Brain Barrier ◽

Brain Endothelial Cell ◽

Efflux Pump Substrates Shuttled to Cytosolic or Vesicular Compartments Exhibit Different Permeability in a Quantitative Human Blood–Brain Barrier Model

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.8b00662 ◽

2018 ◽

Vol 15 (11) ◽

pp. 5081-5088 ◽

Cited By ~ 2

Author(s):

John S. Ruano-Salguero ◽

Kelvin H. Lee

Keyword(s):

Blood Brain Barrier ◽

Human Blood ◽

Efflux Pump ◽

Brain Barrier ◽

Blood Brain ◽

Functionalization of liposomes with ApoE-derived peptides at different density affects cellular uptake and drug transport across a blood-brain barrier model

Nanomedicine Nanotechnology Biology and Medicine ◽

10.1016/j.nano.2011.05.004 ◽

2011 ◽

Vol 7 (5) ◽

pp. 551-559 ◽

Cited By ~ 100

Author(s):

Francesca Re ◽

Ilaria Cambianica ◽

Cristiano Zona ◽

Silvia Sesana ◽

Maria Gregori ◽

...

Keyword(s):

Blood Brain Barrier ◽

Cellular Uptake ◽

Drug Transport ◽

Brain Barrier ◽

Blood Brain ◽

Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood–brain barrier model for drug uptake and transport studies

Brain Research ◽

10.1016/s0006-8993(03)03443-7 ◽

2003 ◽

Vol 990 (1-2) ◽

pp. 95-112 ◽

Cited By ~ 162

Author(s):

Yadollah Omidi ◽

Lee Campbell ◽

Jaleh Barar ◽

David Connell ◽

Saeed Akhtar ◽

...

Keyword(s):

Endothelial Cell ◽

Drug Uptake ◽

Capillary Endothelial Cell ◽

Brain Capillary Endothelial Cell ◽

Brain Capillary ◽

Transport Studies ◽

Barrier Model ◽

Uptake And Transport

Brain microvascular endothelial-astrocyte cell responses following Japanese encephalitis virus infection in an in vitro human blood-brain barrier model

Molecular and Cellular Neuroscience ◽

10.1016/j.mcn.2018.04.002 ◽

2018 ◽

Vol 89 ◽

pp. 60-70 ◽

Cited By ~ 14

Author(s):

Adjanie Patabendige ◽

Benedict D. Michael ◽

Alister G. Craig ◽

Tom Solomon

Keyword(s):

Virus Infection ◽

Japanese Encephalitis Virus ◽

Blood Brain Barrier ◽

Japanese Encephalitis ◽

Human Blood ◽

Japanese Encephalitis Virus Infection ◽

Cell Responses ◽

Differential chemokine expression under the control of peripheral blood mononuclear cells issued from Alzheimer’s patients in a human blood brain barrier model

PLoS ONE ◽

10.1371/journal.pone.0201232 ◽

2018 ◽

Vol 13 (8) ◽

pp. e0201232 ◽

Cited By ~ 2

Author(s):

Julie Vérité ◽

Guylène Page ◽

Marc Paccalin ◽

Adrien Julian ◽

Thierry Janet

Keyword(s):

Blood Brain Barrier ◽

Peripheral Blood Mononuclear Cells ◽

Human Blood ◽

Peripheral Blood ◽

Mononuclear Cells ◽

Brain Barrier ◽

Peripheral Blood Mononuclear ◽

Blood Mononuclear Cells ◽

A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources

Scientific Reports ◽

10.1038/srep04160 ◽

2014 ◽

Vol 4 (1) ◽

Cited By ~ 204

Author(s):

Ethan S. Lippmann ◽

Abraham Al-Ahmad ◽

Samira M. Azarin ◽

Sean P. Palecek ◽

Eric V. Shusta

Keyword(s):

Stem Cell ◽

Retinoic Acid ◽

Blood Brain Barrier ◽

Human Blood ◽

Brain Barrier ◽

Blood Brain ◽

Cell Sources ◽