Correlation of past tuberculosis with current screening for female genital tuberculosis in infertile women in a tertiary care hospital

Author(s):  
Maruti Sinha ◽  
Rekha Rani ◽  
Poonam Bagga
2016 ◽  
Vol 16 (2) ◽  
pp. 101-108 ◽  
Author(s):  
Jai Bhagwan Sharma ◽  
Jayaramaiah Sneha ◽  
Urvashi B. Singh ◽  
Sunesh Kumar ◽  
Kallol Kumar Roy ◽  
...  

2021 ◽  
pp. 73-76
Author(s):  
Vinita Sarbhai ◽  
Aafreen Naaz ◽  
Vikram Sarbhai

INTRODUCTION: Female genital tuberculosis (FGTB) is difcult to diagnose due to asymptomatic presentation and paucity of denitive investigations. Hysteroscopy can be utilized for the diagnosis of genital tuberculosis in infertile women. This study was done to study the role of hysteroscopy in the diagnosis of genital tuberculosis. METHODS: Prospective observational study was performed on 50 infertile women after basic evaluation of infertility. The women with tubal factors for infertility or unexplained infertility were selected for the study. Premenstrual endometrial biopsy (EB) was done for mycobacteria (AFB) detection. Hysteroscopy was performed in the next cycle if no AFB was detected on EB. ATT was given if genital TB was diagnosed on EB, and hysteroscopy was performed after completion of ATT. Hysteroscopic observations were compared with endometrial biopsy results. RESULTS: A total of 4 (8%) cases were diagnosed as bacteriologically positive for genital tuberculosis in endometrial samples. They were given anti-tubercular treatment. On hysteroscopy, pale endometrium (16%), Intrauterine adhesions (46%), and osteal obliteration (18%) were the common abnormal observations. 12 patients had mild adhesions, 6 had moderate and 5 patients had severe adhesions. Overall, 26 (52%) patients had features of intrauterine brosis, like intra-uterine adhesions or ostial obliteration, which could be suggestive of chronic infection like tuberculosis. Hysteroscopic adhesiolysis was performed in 46% and the cavity was restored. CONCLUSION: Endometrial Biopsy and Hysteroscopy are complementary procedures that together can help in the diagnosis of FGTB. Hysteroscopy is not only the gold standard for diagnosing uterine adhesions, distortion of the uterine cavity and tubal ostia, but it can also be a prognostic and therapeutic tool.


Author(s):  
Aafreen Naaz ◽  
Vikram Sarbhai ◽  
Vinita Sarbhai

Background: The diagnosis of female genital TB is challenging due to low sensitivity of conventional diagnostic modalities. The new GeneXpert Test on endometrial biopsy is studied for its role in diagnosis of female genital TB.Methods: This is an observational cross-sectional study on 50 infertile women. Premenstrual endometrial biopsy was performed and sent for AFB Smear, M. TB (LJ) medium culture, CB-NAAT by GeneXpert, and histopathology. The results were compared for diagnosis of FGTB.Results: Endometrial Biopsy (EB) could confirm diagnosis of genital TB in 4 cases (8%) out of 50 infertile women. Amongst these 4 cases, GeneXpert was positive in two, AFB were detected on smear in three while one showed both AFB on smear and positive GeneXpert. GeneXpert adds additional value but surely cannot replace any of the other gold standard investigations.Conclusions: GeneXpert is a rapid diagnostic method which is accurate, feasible and affordable. It is useful adjunct to the existing armamentarium in diagnosis of female genital tuberculosis.


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