The relationship of asthma medication use to perinatal outcomes

2004 ◽  
Vol 113 (6) ◽  
pp. 1040-1045 ◽  
Author(s):  
Michael Schatz ◽  
Mitchell P. Dombrowski ◽  
Robert Wise ◽  
Valerija Momirova ◽  
Mark Landon ◽  
...  
Keyword(s):  
Medication Use ◽  
Perinatal Outcomes ◽  
Asthma Medication ◽  
Relationship Of ◽  
The Relationship

Reduced Growth in Non-Small for Gestational Age Fetuses from 35 Weeks of Gestation to Birth and Perinatal Outcomes

2021 ◽  
pp. 1-10
Author(s):  
Peña Dieste Pérez ◽  
Luis M. Esteban ◽  
Ricardo Savirón-Cornudella ◽  
Faustino R. Pérez-López ◽  
Sergio Castán-Mateo ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Perinatal Outcomes ◽  
Entire Study ◽  
Birth Weight Percentile ◽  
Gestational Age At Delivery ◽  
Study Population ◽  
The Difference ◽  
Relationship Of ◽  
The Relationship

<b><i>Objective:</i></b> This study aimed to assess reduced fetal growth between 35 weeks of gestation and birth in non-small for gestational age fetuses associated with adverse perinatal outcomes (APOs). <b><i>Material and Method:</i></b> It is a retrospective cohort study of 9,164 non-small for gestational age fetuses estimated by ultrasound at 35 weeks. The difference between the birth weight percentile and the estimated percentile weight (EPW) at 35 weeks of gestation was calculated, and we studied the relationship of this difference with the appearance of APO. APOs were defined as cesarean or instrumental delivery rates for nonreassuring fetal status, 5-min Apgar score &#x3c;7, arterial cord blood pH &#x3c;7.10, and stillbirth. Fetuses that exhibited a percentile decrease between both moments were classified into 6 categories according to the amount of percentile decrease (0.01–10.0, 10.01–20.0, 20.01–30.0, 30.01–40.0, 40.01–50.0, and &#x3e;50.0 percentiles). It was evaluated whether the appearance of APO was related to the amount of this percentile decrease. Relative risk (RR) was calculated in these subgroups to predict APOs in general and for each APO in particular. Receiver operating characteristic and area under curves (AUC) for the difference in the percentile was calculated, used as a continuous parameter in the entire study population. <b><i>Results:</i></b> The median gestational age at delivery in uncomplicated pregnancies was 40.0 (39.1–40.7) and in pregnancies with APOs 40.3 (49.4–41.0), <i>p</i> &#x3c; 0.001. The prevalence of APOs was greater in the group of fetuses with a decrease in percentile (7.6%) compared to those with increased percentile (4.8%) (<i>p</i> &#x3c; 0.001). The RR was 1.63 (95% CI: 1.365–1.944, <i>p</i> &#x3c; 0.001). Although the differences were significant in all decreased percentile groups, RRs were significantly higher when decreased growth values were &#x3e;40 points (RR: 2.036, 95% CI: 1.581–2.623, <i>p</i> &#x3c; 0.001). The estimated value of the AUC for percentile decrease was 0.58 (0.56–0.61, <i>p</i> &#x3c; 0.001). <b><i>Conclusion:</i></b> Fetuses with a decrease in the EPW between the ultrasound at 35 weeks of gestation and birth have a higher risk of APOs, being double in fetuses with a decrease of &#x3e;40 percentile points.

scholarly journals SA63. Pilot Study Examining the Relationship of Childhood Trauma, Perceived Stress, and Medication Use to Serum Kynurenic Acid and Kynurenine Levels in Schizophrenia

2017 ◽  
Vol 43 (suppl_1) ◽  
pp. S135-S136
Author(s):  
Bridget Shovestul ◽  
Matthew Glassman ◽  
Laura Rowland ◽  
Robert McMahon ◽  
Fang Liu ◽  
...  
Keyword(s):  
Pilot Study ◽  
Childhood Trauma ◽  
Perceived Stress ◽  
Kynurenic Acid ◽  
Medication Use ◽  
Relationship Of ◽  
The Relationship

scholarly journals The Link Between Obesity and Asthma: A Canadian Perspective

2007 ◽  
Vol 14 (4) ◽  
pp. 217-220 ◽  
Author(s):  
Louis-Philippe Boulet ◽  
Annick Des Cormiers
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Medication Use ◽  
Canadian Community Health Survey ◽  
Causal Link ◽  
Asthma Medication ◽  
Community Health Survey ◽  
Canadian Perspective ◽  
Obese Subjects ◽  
The Relationship

Asthma is considered to be more prevalent in obese subjects, and a possible causal link between these two entities has been suggested. In the present study, various observations on this relationship were reviewed, and an analysis of data obtained from the 2000 to 2001 Canadian Community Health Survey on the prevalence of self-reported asthma, medication use and allergy, according to body weight, was reported. Asthma medication use and self-reported asthma were more prevalent in the obese population, particularly in women. Mean body mass index was higher in the asthmatic population compared with the nonasthmatic population. Self-reported nonfood-related allergies were higher in the more obese subjects in the general population, but the prevalence of allergy was not different in obese asthmatic subjects compared with nonobese asthmatic subjects. Smoking did not seem to influence the relationship between asthma and body mass index. Further research should investigate the mechanisms by which obesity may influence the prevalence of asthma or asthma-like symptoms.

Parental Perceptions of Health Status and Psychologic Adjustment of Children With Asthma

PEDIATRICS ◽  
1989 ◽  
Vol 83 (1) ◽  
pp. 26-30
Author(s):  
James M. Perrin ◽  
William E. MacLean ◽  
Ellen C. Perrin
Keyword(s):  
Medication Use ◽  
Objective Measure ◽  
Health Resources ◽  
Severity Of Illness ◽  
Clinical History ◽  
Parental Report ◽  
Children With Asthma ◽  
Two Measures ◽  
Relationship Of ◽  
The Relationship

The relationship between severity of illness and psychologic adjustment was evaluated in 46 children with asthma. Two measures of the severity of asthma were used: the first, a composite objective measure based on clinical history and the second, parental estimates of the severity of their child's illness. Psychologic adjustment was measured by the Health Resources Inventory, a parental report of childhood behavior. Parental estimates of severity were correlated significantly with the objective measure of severity (r = .39; P &lt; .01), although a concordance value of 54% indicated marked lack of agreement between parental and objective ratings. As a group, children in this study achieved apparently normal adjustment scores, although scores ranged widely across all categories of severity. Children whose parents ranked their asthma as mild or severe had significantly lower adjustment scores (F = 3.28; P &lt; .05) than did those children rated by their parents as having moderate asthma. Children's ranks on the composite objective measure of severity were not associated with their adjustment scores, although children with greater use of medication had lower adjustment scores than did children with little or moderate medication use (P &lt; .05). The relationship of severity of illness to psychologic adjustment is complex. Children at all levels of severity may demonstrate problems of adjustment, suggesting that attention to psychologic risk should not be limited only to children with severe asthma.

scholarly journals Pilot study examining the relationship of childhood trauma, perceived stress, and medication use to serum kynurenic acid and kynurenine levels in schizophrenia

2017 ◽  
Vol 185 ◽  
pp. 200-201 ◽  
Author(s):  
Bridget J. Shovestul ◽  
Matthew Glassman ◽  
Laura M. Rowland ◽  
Robert P. McMahon ◽  
Fang Liu ◽  
...  
Keyword(s):  
Pilot Study ◽  
Childhood Trauma ◽  
Perceived Stress ◽  
Kynurenic Acid ◽  
Medication Use ◽  
Relationship Of ◽  
The Relationship

The relationship of the scleractinian corals to the rugose corals

Paleobiology ◽  
1980 ◽  
Vol 6 (02) ◽  
pp. 146-160 ◽  
Author(s):  
William A. Oliver
Keyword(s):  
Critical Points ◽  
Scleractinian Corals ◽  
Convincing Evidence ◽  
Early Triassic ◽  
Rugose Corals ◽  
History Of ◽  
The Subject ◽  
Relationship Of ◽  
The Relationship ◽  
Biologic Factors

The Mesozoic-Cenozoic coral Order Scleractinia has been suggested to have originated or evolved (1) by direct descent from the Paleozoic Order Rugosa or (2) by the development of a skeleton in members of one of the anemone groups that probably have existed throughout Phanerozoic time. In spite of much work on the subject, advocates of the direct descent hypothesis have failed to find convincing evidence of this relationship. Critical points are:(1) Rugosan septal insertion is serial; Scleractinian insertion is cyclic; no intermediate stages have been demonstrated. Apparent intermediates are Scleractinia having bilateral cyclic insertion or teratological Rugosa.(2) There is convincing evidence that the skeletons of many Rugosa were calcitic and none are known to be or to have been aragonitic. In contrast, the skeletons of all living Scleractinia are aragonitic and there is evidence that fossil Scleractinia were aragonitic also. The mineralogic difference is almost certainly due to intrinsic biologic factors.(3) No early Triassic corals of either group are known. This fact is not compelling (by itself) but is important in connection with points 1 and 2, because, given direct descent, both changes took place during this only stage in the history of the two groups in which there are no known corals.

Skeletal elements of crinoid echinoderms: High-resolution structural and microanalytical results

1983 ◽  
Vol 41 ◽  
pp. 194-195
Author(s):  
D. F. Blake ◽  
L. F. Allard ◽  
D. R. Peacor
Keyword(s):  
High Resolution ◽  
Marine Invertebrates ◽  
Sea Urchins ◽  
Structural Features ◽  
Sea Stars ◽  
High Resolution Tem ◽  
Relationship Of ◽  
The Relationship ◽  
Insight Into

Echinodermata is a phylum of marine invertebrates which has been extant since Cambrian time (c.a. 500 m.y. before the present). Modern examples of echinoderms include sea urchins, sea stars, and sea lilies (crinoids). The endoskeletons of echinoderms are composed of plates or ossicles (Fig. 1) which are with few exceptions, porous, single crystals of high-magnesian calcite. Despite their single crystal nature, fracture surfaces do not exhibit the near-perfect {10.4} cleavage characteristic of inorganic calcite. This paradoxical mix of biogenic and inorganic features has prompted much recent work on echinoderm skeletal crystallography. Furthermore, fossil echinoderm hard parts comprise a volumetrically significant portion of some marine limestones sequences. The ultrastructural and microchemical characterization of modern skeletal material should lend insight into: 1). The nature of the biogenic processes involved, for example, the relationship of Mg heterogeneity to morphological and structural features in modern echinoderm material, and 2). The nature of the diagenetic changes undergone by their ancient, fossilized counterparts. In this study, high resolution TEM (HRTEM), high voltage TEM (HVTEM), and STEM microanalysis are used to characterize tha ultrastructural and microchemical composition of skeletal elements of the modern crinoid Neocrinus blakei.

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