Immediate and long-term effects of bilateral electroconvulsive therapy on cognitive functioning in patients with a depressive disorder

2018 ◽  
Vol 238 ◽  
pp. 659-665 ◽  
Author(s):  
Jasper O. Nuninga ◽  
Thomas F.I. Claessens ◽  
Metten Somers ◽  
René Mandl ◽  
Wendy Nieuwdorp ◽  
...  
Keyword(s):  
Depressive Disorder ◽  
Cognitive Functioning ◽  
Electroconvulsive Therapy ◽  
Long Term Effects

The Long-Term Effects of Mindfulness-Based Cognitive Therapy as a Relapse Prevention Treatment for Major Depressive Disorder

2010 ◽  
Vol 38 (5) ◽  
pp. 561-576 ◽  
Author(s):  
Kate L. Mathew ◽  
Hayley S. Whitford ◽  
Maura A. Kenny ◽  
Linley A. Denson
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Cognitive Therapy ◽  
Relapse Prevention ◽  
Mindfulness Practice ◽  
Long Term Effects ◽  
Major Depressive ◽  
Strong Negative Correlation ◽  
Group 3

Background: Mindfulness-based Cognitive Therapy (MBCT) is a relapse prevention treatment for major depressive disorder. Method: An observational clinical audit of 39 participants explored the long-term effects of MBCT using standardized measures of depression (BDI-II), rumination (RSS), and mindfulness (MAAS). Results: MBCT was associated with statistically significant reductions in depression from pre to post treatment. Gains were maintained over time (Group 1, 1–12 months, p = .002; Group 2, 13–24 months, p = .001; Group 3, 25–34 months, p = .04). Depression scores in Group 3 did begin to worsen, yet were still within the mild range of the BDI-II. Treatment variables such as attendance at “booster” sessions and ongoing mindfulness practice correlated with better depression outcomes (p = .003 and p = .03 respectively). There was a strong negative correlation between rumination and mindful attention (p < .001), consistent with a proposed mechanism of metacognition in the efficacy of MBCT. Conclusion: It is suggested that ongoing MBCT skills and practice may be important for relapse prevention over the longer term. Larger randomized studies of the mechanisms of MBCT with longer follow-up periods are recommended.

Short-term and long-term effects of major depressive disorder subtypes on obesity markers and impact of sex on these associations

2021 ◽  
Author(s):  
Clémentine Ottino ◽  
Marie-Pierre F Strippoli ◽  
Mehdi Gholam ◽  
Aurélie M Lasserre ◽  
Caroline L Vandeleur ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Long Term Effects ◽  
Short Term ◽  
Major Depressive

The long-term effects of cocaine use on cognitive functioning: A systematic critical review

2018 ◽  
Vol 348 ◽  
pp. 241-262 ◽  
Author(s):  
Kirsten M. Frazer ◽  
Qwynten Richards ◽  
Diana R. Keith
Keyword(s):  
Cognitive Functioning ◽  
Critical Review ◽  
Long Term Effects ◽  
Cocaine Use

scholarly journals Long-term effects of intracranial islet grafting on cognitive functioning in a rat metabolic model of sporadic Alzheimer's disease-like dementia

PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0227879
Author(s):  
Konstantin Bloch ◽  
Shay Henry Hornfeld ◽  
Shira Dar ◽  
Alexey Vanichkin ◽  
Irit Gil-Ad ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Functioning ◽  
Metabolic Model ◽  
Long Term Effects ◽  
Sporadic Alzheimer’S Disease

scholarly journals Acute and long-term effects of electroconvulsive therapy on human dentate gyrus

2019 ◽  
Vol 44 (10) ◽  
pp. 1805-1811 ◽  
Author(s):  
Akihiro Takamiya ◽  
Eric Plitman ◽  
Jun Ku Chung ◽  
Mallar Chakravarty ◽  
Ariel Graff-Guerrero ◽  
...  
Keyword(s):  
Dentate Gyrus ◽  
Electroconvulsive Therapy ◽  
Long Term Effects

Citicoline in the Treatment of Mild Cognitive Impairment in Blood Relatives of Patients with Alzheimer’s Disease: Immediate and Long-Term Effects of Course Therapy

Psychiatry ◽  
2021 ◽  
Vol 19 (4) ◽  
pp. 42-51
Author(s):  
N. D. Seleznеva ◽  
I. F. Roshchina ◽  
E. V. Ponomareva ◽  
S. Iv. Gavrilova
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Functioning ◽  
Cognitive Dysfunction ◽  
Therapeutic Effects ◽  
Long Term Effects ◽  
Voluntary Attention

The aim was to study immediate and long-term (post-therapeutic) effects of a three-month course of therapy with citicoline in 1st-degree relatives of patients with Alzheimer’s disease (AD). All the included relatives of patients with AD revealed signs of minimal cognitive dysfunction (MCD) and mild cognitive decline syndrome (MCI — Mild Cognitive Impairment, ICD-10 code F06.7). Study participants: the study involved 90 first-degree relatives: 24 with MCI and 66 with MCD. Study design: an open-label comparative multidisciplinary study of the six-month dynamics of cognitive functioning of two groups of relatives who received a three-month course of citicoline therapy. The baseline indicators of the cognitive functioning of relatives with MCI syndrome and MKD were compared with the indicators at the end of the three-month course of therapy with citicoline at a daily dose of 1000 mg as well as 3 months after the end of the course of treatment. Methods: clinical, psychopathological, neuropsychological, psychometric, genetic, statistical ones. Results: а significant positive effect of the course therapy with citicoline on the cognitive impairment of 1st degree AD-patients’ relatives with minimal cognitive dysfunction and more pronounced cognitive impairments met the diagnostic criteria for MCI syndrome has been found. A significantly greater value of both immediate and long-term therapeutic effect of MKD compared with MCI in relatives was established by psychometric and neuropsychological indicators characterizing voluntary memorization of verbal and visual stimuli, optical and spatial activity, voluntary attention, and associative verbal thinking. Conclusion: the results of the study can be used as the basis for a model of prevention of the progression of cognitive deficit and the development of dementia in persons with a high risk of developing AD, i.e. in individuals with both genetic risk and signs of cognitive impairment.

Mode of action of electroconvulsive therapy: an update

2011 ◽  
Vol 17 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Allan I. F. Scott
Keyword(s):  
Mood Disorders ◽  
Electroconvulsive Therapy ◽  
Mode Of Action ◽  
Imaging Techniques ◽  
Long Term Effects ◽  
Cellular Mechanisms ◽  
Know How ◽  
Antidepressant Treatments ◽  
New Findings

SummaryIt has become acceptable for psychiatrists to say that they simply do not know how electroconvulsive therapy (ECT) works. This frame of mind runs the risk that there will be no expectation that psychiatrists remain familiar with seminal studies on the mode of action of ECT. This article is intended as a reminder of these studies and illustrates how the original theories have evolved. This evolution has been brought about largely by modern brain imaging techniques in human studies and in patients treated with ECT. These new findings will be set in the context of contemporary ideas about the neuroanatomy of mood disorders and the cellular mechanisms of the long-term effects of antidepressant treatments.

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