Relationship between upper limb physical performance tests and muscle strength of scapular, shoulder and spine stabilizers: a cross-sectional study

Impaired physical performance is common in patients on hemodialysis (HD) and is associated with poor prognosis. A patient relevant marker of adequacy of dialysis is lacking. Previous studies evaluated uremic toxicity by assessing the impact of different uremic toxins separately. However, such an approach is most likely not reflective of true uremic toxicity. Therefore, this cross-sectional study aimed to examine if the uremic syndrome, estimated as one composite of different uremic toxins (facilitated by ridge regression method) to reflect the kinetic behavior during dialysis, is associated with physical performance in patients on HD. Levels of p-cresyl glucuronide and sulfate, indole-acetic acid, indoxyl sulfate, uric acid, hippuric acid, and 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid were assessed and associated by ridge regression to muscle strength, functional exercise capacity, and measures of balance and coordination. 75 HD patients were included (mean age 68 years, 57% male). The composite of different uremic toxins (i.e., uremic load) explained 22% of the variance in handgrip strength. Although there was an association between full body muscle strength and the composite uremic load independent of nutritional status, age and gender, the predictive power of composite uremic load for muscle weakness is limited. Single uremic toxins as well as composite uremic load were not associated with exercise capacity, coordination, and balance, indicating that the degree of uremia does not predict physical performance in patients on HD.

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The Structural Index Score and its relation to foot function, disability and physical performance tests in rheumatoid arthritis (RA) – a cross-sectional study

The Foot ◽

10.1016/j.foot.2021.101876 ◽

2021 ◽

pp. 101876

Author(s):

Juliana Zonzini Gaino ◽

Manoel Barros Bértolo ◽

Caroline Silva Nunes ◽

Zoraida Sachetto ◽

Síbila Floriano Landim ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Physical Performance ◽

Cross Sectional Study ◽

Index Score ◽

Performance Tests ◽

Sectional Study ◽

Structural Index ◽

Cross Sectional ◽

Foot Function

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Sarcopenia-related features and factors associated with lower muscle strength and physical performance in older Chinese: a cross sectional study

BMC Geriatrics ◽

10.1186/s12877-016-0220-7 ◽

2016 ◽

Vol 16 (1) ◽

Cited By ~ 13

Author(s):

Ping Zeng ◽

Yiwen Han ◽

Jing Pang ◽

Sinan Wu ◽

Huan Gong ◽

...

Keyword(s):

Muscle Strength ◽

Physical Performance ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Factors Associated ◽

Older Chinese

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Relationship of anabolic and catabolic biomarkers with muscle strength and physical performance in older adults: a population-based cross-sectional study

BMC Musculoskeletal Disorders ◽

10.1186/s12891-015-0654-7 ◽

2015 ◽

Vol 16 (1) ◽

Cited By ~ 13

Author(s):

Yongxia Meng ◽

Hongmei Wu ◽

Yi Yang ◽

Huanmin Du ◽

Yang Xia ◽

...

Keyword(s):

Older Adults ◽

Muscle Strength ◽

Physical Performance ◽

Population Based ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Relationship Of

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Effect of vitamin D status on muscle function and physical performance among saudi postmenopausal women: a cross-sectional study

Bone Abstracts ◽

10.1530/boneabs.1.pp301 ◽

2013 ◽

Author(s):

Khulood Hussein

Keyword(s):

Vitamin D ◽

Postmenopausal Women ◽

Physical Performance ◽

Muscle Function ◽

Cross Sectional Study ◽

Vitamin D Status ◽

Sectional Study ◽

Cross Sectional

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Increased modifiable cardiovascular risk factors in patients with Takayasu arteritis: a multicenter cross-sectional study

Advances in Rheumatology ◽

10.1186/s42358-020-00157-1 ◽

2021 ◽

Vol 61 (1) ◽

Author(s):

Alexandre Moura dos Santos ◽

Rafael Giovani Misse ◽

Isabela Bruna Pires Borges ◽

Bruno Gualano ◽

Alexandre Wagner Silva de Souza ◽

...

Keyword(s):

Quality Of Life ◽

Risk Factors ◽

Muscle Strength ◽

Aerobic Capacity ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Metabolic Equivalent ◽

Handgrip Test

Abstract Background Modifiable cardiovascular risk factors (MCRFs), such as those related to aerobic capacity, muscle strength, physical activity, and body composition, have been poorly studied in Takayasu arteritis (TAK). Therefore, the aim of the study was to investigate MCRFs and their relationships with disease status and comorbidities among patients with TAK. Methods A multicenter cross-sectional study was conducted between 2019 and 2020, in which 20 adult women with TAK were compared with 16 healthy controls matched by gender, age, and body mass index. The following parameters were analyzed: aerobic capacity by cardiopulmonary test; muscle function by timed-stands test, timed up-and-go test, and handgrip test; muscle strength by one-repetition maximum test and handgrip test; body composition by densitometry; physical activity and metabolic equivalent by IPAQ, quality of life by HAQ and SF-36; disease activity by ITAS2010 and NIH score; and presence of comorbidities. Results Patients with TAK had a mean age of 41.5 (38.0–46.3) years, disease duration of 16.0 (9.5–20.0) years, and a mean BMI of 27.7±4.5 kg/m2. Three out of the 20 patients with TAK had active disease. Regarding comorbidities, 16 patients had systemic arterial hypertension, 11 had dyslipidemia, and two had type 2 diabetes mellitus, while the control group had no comorbidities. TAK had a significant reduction in aerobic capacity (absolute and relative VO2 peak), muscle strength in the lower limbs, increased visceral adipose tissue, waist-to-hip ratio, reduced walking capacity, decreased weekly metabolic equivalent, and quality of life (P< 0.05) as compared to controls. However, there were no correlations between these MCRFs parameters and disease activity. Conclusions TAK show impairment in MCRFs; therefore, strategies able to improve MCRF should be considered in this disease.

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