scholarly journals Sarcopenia-related features and factors associated with lower muscle strength and physical performance in older Chinese: a cross sectional study

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Ping Zeng ◽  
Yiwen Han ◽  
Jing Pang ◽  
Sinan Wu ◽  
Huan Gong ◽  
...  
PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0119914 ◽  
Author(s):  
Suxing Shen ◽  
Jing Li ◽  
Qi Guo ◽  
Wen Zhang ◽  
Xiuyang Wang ◽  
...  

Toxins ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 135
Author(s):  
Karsten Vanden Wyngaert ◽  
Amaryllis H. Van Craenenbroeck ◽  
Els Holvoet ◽  
Patrick Calders ◽  
Wim Van Biesen ◽  
...  

Impaired physical performance is common in patients on hemodialysis (HD) and is associated with poor prognosis. A patient relevant marker of adequacy of dialysis is lacking. Previous studies evaluated uremic toxicity by assessing the impact of different uremic toxins separately. However, such an approach is most likely not reflective of true uremic toxicity. Therefore, this cross-sectional study aimed to examine if the uremic syndrome, estimated as one composite of different uremic toxins (facilitated by ridge regression method) to reflect the kinetic behavior during dialysis, is associated with physical performance in patients on HD. Levels of p-cresyl glucuronide and sulfate, indole-acetic acid, indoxyl sulfate, uric acid, hippuric acid, and 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid were assessed and associated by ridge regression to muscle strength, functional exercise capacity, and measures of balance and coordination. 75 HD patients were included (mean age 68 years, 57% male). The composite of different uremic toxins (i.e., uremic load) explained 22% of the variance in handgrip strength. Although there was an association between full body muscle strength and the composite uremic load independent of nutritional status, age and gender, the predictive power of composite uremic load for muscle weakness is limited. Single uremic toxins as well as composite uremic load were not associated with exercise capacity, coordination, and balance, indicating that the degree of uremia does not predict physical performance in patients on HD.


Author(s):  
Agnes Ramos Guirelli ◽  
Júlia Maria dos Santos ◽  
Estêvão Mállon Gomes Cabral ◽  
João Pedro Camilo Pinto ◽  
Gabriel Alves De Lima ◽  
...  

BMJ Open ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. e019775 ◽  
Author(s):  
Yanfeng Zhou ◽  
Jiang Wu ◽  
Shenchao Zhang ◽  
Shijiao Yan ◽  
Liping He ◽  
...  

ObjectiveInvestigations on physical inactivity are common around the world; however, little is known about the status of physical inactivity in mainland China. The aim of this study was to examine the prevalence and risk factors associated with physical inactivity in Shenzhen in Southern China.DesignA community-based, cross-sectional study.SettingA multistage-stratified, random cluster survey was conducted in Xixiang Street, Bao’an District of Shenzhen in Southeast China.Participants3920 adults aged 40 years or more were recruited to the study and completed the International Physical Activity Questionnaire Short Form between 1 March 2015 and 30 July 2016.Main outcome measuresPhysical inactivity was defined as engaging in physical activity levels insufficient to reach the current guidelines. Bivariate and multivariate analyses were undertaken to assess the prevalence and risk factors associated with physical inactivity.ResultsThe prevalence of physical inactivity was 63.1% for all participants, 63.9% for women and 61.9% for men, respectively. Participants who were older (OR=1.31, 95% CI 1.11 to 1.54), who were female (OR=1.22, 95% CI 1.04 to 1.43), who had higher education experience (OR=1.38, 95% CI 1.19 to 1.61), who are under economic pressure (OR=2.17, 95% CI 1.48 to 3.17), who ever smoked a cigarette (OR=1.44, 95% CI 1.13 to 1.82) and drank alcohol (OR=1.42, 95% CI 1.14 to 1.77), and participants in the lowest body mass index category (OR=1.40, 95% CI 1.03 to 1.89), were more likely to report physical inactivity.ConclusionsThese findings indicate that physical inactivity is prevalent in Southern China. Interventions and programmes aimed at increasing physical activity among middle-aged and older Chinese adults may also be tailored to participants under economic pressure and those with unhealthy behaviours such as smoking and drinking.


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