Predictive value of simple clinical and laboratory variables for dengue hemorrhagic fever in adults

2008 ◽  
Vol 42 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Vernon J. Lee ◽  
David C.B. Lye ◽  
Yan Sun ◽  
Gina Fernandez ◽  
Adrian Ong ◽  
...  
Keyword(s):  
Dengue Hemorrhagic Fever ◽  
Predictive Value ◽  
Hemorrhagic Fever ◽  
Laboratory Variables

scholarly journals The Usefulness of Clinical-Practice-Based Laboratory Data in Facilitating the Diagnosis of Dengue Illness

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Jien-Wei Liu ◽  
Ing-Kit Lee ◽  
Lin Wang ◽  
Rong-Fu Chen ◽  
Kuender D. Yang
Keyword(s):  
Clinical Practice ◽  
Predictive Value ◽  
Viral Infections ◽  
Laboratory Data ◽  
Hemorrhagic Fever ◽  
Complementary Role ◽  
Prolonged Aptt ◽  
Laboratory Variables ◽  
Sensitivity Specificity

Alertness to dengue and making a timely diagnosis is extremely important in the treatment of dengue and containment of dengue epidemics. We evaluated the complementary role of clinical-practice-based laboratory data in facilitating suspicion/diagnosis of dengue. One hundred overall dengue (57 dengue fever [DF] and 43 dengue hemorrhagic fever [DHF]) cases and another 100 nondengue cases (78 viral infections other than dengue, 6 bacterial sepsis, and 16 miscellaneous diseases) were analyzed. We separately compared individual laboratory variables (platelet count [PC] , prothrombin time [PT], activated partial thromboplastin time [APTT], alanine aminotransferase [ALT], and aspartate aminotransferase [AST]) and varied combined variables of DF and/or DHF cases with the corresponding ones of nondengue cases. The sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) in the diagnosis of DF and/or DHF were measured based on these laboratory variables. While trade-off between sensitivity and specificity, and/or suboptimal PPV/NPV was found at measurements using these variables, prolonged APTT + normal PT + PC < 100 × 109cells/L had a favorable sensitivity, specificity, PPV, and NPV in diagnosis of DF and/or DHF. In conclusion, these data suggested that prolonged APTT + normal PT + PC < 100 × 109cells/L is useful in evaluating the likelihood of DF and/or DHF.

scholarly journals UJI CEPAT (RAPID TEST) ANTIBODI IgM TERHADAP Salmonella typhi DEMAM TIFOID

2018 ◽  
Vol 14 (3) ◽  
pp. 109
Author(s):  
Rini Riyant ◽  
Prihatini . ◽  
Siti Rochmatoen
Keyword(s):  
Typhoid Fever ◽  
Dengue Hemorrhagic Fever ◽  
Predictive Value ◽  
Rapid Test ◽  
Hemorrhagic Fever ◽  
Diagnostic Value ◽  
Salmonella Typhi ◽  
Diagnostic Efficiency ◽  
Igm Antibodies ◽  
Health Centres

Typhoid fever is caused by Salmonella typhi. The definitive diagnosis can be made by isolation of Salmonella typhi from blood, bone marrow or other body fluids. To support the clinical diagnosis of typhoid fever in Indonesia, where most hospitals and health centres haveno facilities for cultures, a rapid test for the detection of lipopolysaccharides (LPS) Salmonella typhi-specific IgM antibodies was evaluatedon serum samples from patients with typhoid fever. This study is proposed to know the rapid test diagnostic value for the detection oflipopolysaccharides (LPS) Salmonella typhi-specific IgM antibodies. A cross sectional, observational analytical study on 27 typhoidfever and 25 dengue hemorrhagic fever patients of the Dr. Soetomo Hospital, Dr. M Soewandhi General Hospital and Gotong-RoyongClinic has been conducted from January – May 2007. The diagnosis of typhoid fever patients was based on positive gall culture whilethe diagnosis of dengue hemorrhagic fever was based on negative gall culture, positive serology examination for dengue hemorrhagicfever and a recovery from dengue hemorrhagic fever with standard treatment. The sera from patients were examined using a rapid testfor the detection of lipopolysacharides (LPS) Salmonella typhi specific IgM antibodies from Amgenix Onsight of the first blood samples(collected on admission to the hospital) the rapid test for IgM antibodies showed the following: sensitivity 70.4%, specificity 80.0%,positive predictive value 79.2%, negative predictive value 71.4%, diagnostic efficiency 75% respectively. Of the second blood samples(collected 2–3 weeks during the illness) therapid test for IgM antibodies showed the following: sensitivity 88.9%, positive predictive value 82.8%, negative predictive value 87.0%, and diagnostic efficiency 84.6% respectively. The rapid test for IgM antibodies has a high diagnostic value for typhoid fever. The assay uses stabilized components which can be stored at room temperature; the test does notrequire special equipment and may be used in health centres that have no facilities for culture.

PENGARUH PELATIHAN PENGENDALIAN VEKTOR DEMAM BERDARAH TERHADAP MAYA INDEX PADA SISWA SEKOLAH DASAR DI MAJALENGKA

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Wawan Kurniawan
Keyword(s):  
Vector Control ◽  
Dengue Fever ◽  
Dengue Hemorrhagic Fever ◽  
Intervention Group ◽  
Hemorrhagic Fever ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Quasi Experimental ◽  
Dengue Vector Control

ABSTRAK  Latar belakang: Demam Berdarah Dengue (DBD) disebabkan oleh virus Dengue dapat menyebabkan kematian. Pencegahan DBD yang dianggap paling tepat adalah Pemberantasan Sarang Nyamuk (PSN). Penelitian ini bertujuan untuk mengetahui pengaruh pelatihan pengendalian vektor Demam Berdarah pada siswa sekolah dasar terhadap Maya Index di Majalengka. Metode: Penelitian ini menggunakan desain quasi experiment (pretest-posttest control group design). Sebanyak 4 sekolah terpilih sebagai kelompok intervensi dan 4 sekolah lainnya sebagai kontrol. Subyek penelitian adalah siswa kelas IV-VI yang terdiri dari 171 siswa pada kelompok intervensi dan 163 pada kelompok kontrol. Instrumen yang digunakan adalah formulir pemantauan jentik berkala. Hasil: Jumlah rumah dengan kategori Maya Index tinggi berkurang dari 27,5% menjadi 9,4%. Terjadi penurunan angka BRI kategori tinggi pada kelompok intervensi dari 20,5% menjadi 1,8%. Pada kelompok kontrol tidak terjadi penurunan angka BRI kategori tinggi (22,1%), sebaliknya terjadi penurunan kategori rendah dari 34,4% menjadi 3,7%. Tidak terjadi penurunan angka HRI pada kelompok intervensi maupun kontrol. Kesimpulan: Pelatihan pengendalian vektor Demam Berdarah dapat menurunkan nilai BRI dan Maya Index, tetapi tidak berpengaruh terhadap nilai HRI. Tidak adanya perubahan nilai HRI menunjukkan bahwa kebersihan dan sanitasi lingkungan merupakan faktor yang berpengaruh terhadap probabilitas kejadian demam berdarah. Kata Kunci : Demam Berdarah, Maya Index, pelatihan, pengendalian vektor   ABSTRACT Background: Dengue Hemorrhagic Fever (DHF) caused by Dengue virus could cause death. The most appropriate prevention of Dengue is eradication of mosquito nests (PSN). This study aims to determine the effect of Dengue vector control training on elementary students towards Maya Index in Majalengka. Method: This study used quasi-experimental design (pretest-posttest control group design). A total of 4 schools were selected as intervention groups and 4 other schools as controls. The subjects were students in grades IV-VI consisting of 171 students in the intervention group and 163 in the control group. The instrument used was periodic larva monitoring form. Results: The number of houses with a high Maya Index category in the intervention group decreased from 27.5% to 9.4%. There was a decrease in the high BRI category in the intervention group from 20.5% to 1.8%. In the control group, there was no decrease in the high BRI category (22.1%), on the contrary, there was a decrease in the low category from 34.4% to 3.7%. There was no decrease in HRI rates both of intervention or control groups. Conclusion: Dengue Fever vector control training could decrease the value of BRI and Maya Index, but does not affect the value of HRI. The absence of changes in HRI  indicate that environmental hygiene and sanitation are factors that influence the probability of dengue fever occurrence. Keywords: Dengue Hemorrhagic Fever, Maya Index, training, vector control

SISTEM PAKAR MENDIAGNOSA VIRUS MAYORA DENGAN METODE VARIABLE CENTERED INTELLIGENT RULE SYSTEM (VCIRS)

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Siti Nurhena ◽  
Nelly Astuti Hasibuan ◽  
Kurnia Ulfa
Keyword(s):  
Artificial Intelligence ◽  
Immune System ◽  
Expert System ◽  
Expert Systems ◽  
Dengue Hemorrhagic Fever ◽  
Hemorrhagic Fever ◽  
Visual Basic ◽  
Artificial Intelligence Techniques ◽  
Individual Needs ◽  
Rule System

The diagnosis process is the first step to knowing a type of disease. This type of disease caused by mosquitoes is one of the major viruses (MAVY), dengue hemorrhagic fever (DHF) and malaria. Sometimes not everyone can find the virus that is carried by this mosquito, usually children who are susceptible to this virus because the immune system that has not been built perfectly is perfect. To know for sure which virus is infected by mosquitoes, it can diagnose by seeing symptoms perceived symptoms. Expert systems are one of the most used artificial intelligence techniques today because expert systems can act as consultations. In this case the authors make a system to start a diagnosis process with variable centered intelligent rule system (VCIRS) methods through perceived symptoms. With the facilities provided for users and administrators, allowing both users and administrators to use this system according to their individual needs. This expert system is made with the Microsoft Visual Basic 2008 programming language.Keywords: Expert System, Mayora Virus, Variable Centered Intelligent Rule System (VCIRS)The diagnosis process is the first step to knowing a type of disease. This type of disease caused by mosquitoes is one of the major viruses (MAVY), dengue hemorrhagic fever (DHF) and malaria. Sometimes not everyone can find the virus that is carried by this mosquito, usually children who are susceptible to this virus because the immune system that has not been built perfectly is perfect. To know for sure which virus is infected by mosquitoes, it can diagnose by seeing symptoms perceived symptoms.Expert systems are one of the most used artificial intelligence techniques today because expert systems can act as consultations. In this case the authors make a system to start a diagnosis process with variable centered intelligent rule system (VCIRS) methods through perceived symptoms.With the facilities provided for users and administrators, allowing both users and administrators to use this system according to their individual needs. This expert system is made with the Microsoft Visual Basic 2008 programming language.Keywords: Expert System, Mayora Virus, Variable Centered Intelligent Rule System (VCIRS)

Difusi dan Pola Spasial Sebaran Penyakit Demam Berdarah Dengue (DBD) Di Kota Bandar Lampung

2018 ◽  
Vol 1 (1) ◽  
pp. 87-95
Author(s):  
Nurul Qamila ◽  
Agel Vidian Krama
Keyword(s):  
Public Health ◽  
Spatial Analysis ◽  
Aedes Aegypti ◽  
Dengue Virus ◽  
Spatial Pattern ◽  
Dengue Hemorrhagic Fever ◽  
Health Problem ◽  
Public Health Problem ◽  
Hemorrhagic Fever ◽  
Descriptive Method

Dengue hemorrhagic fever (DHF) is a contagious disease caused by the dengue virus and is transmitted by the mosquito Aedes aegypti (Aa.aegypti). The population is still a public health problem that increases the number of sufferers and also widespread, with population and education. This study aims to reveal the spatial pattern and distribution of Dengue Hemorrhagic Fever (DHF) with the spatial pattern and the spread of Dengue Hemorrhagic Fever (DHF) can result in different locations of these allegations. From the map that can be used for the prevention of Dengue Hemorrhagic Fever (DBD) in Bandar Lampung City. This study aims to reveal the spatial pattern and distribution of Dengue Hemorrhagic Fever (DHF) with the descriptive method and spatial pattern of Dengue Hemorrhagic Fever (DHF) can result in different locations of these allegations. From the map that can be used for the prevention of Dengue Hemorrhagic Fever (DBD) in Bandar Lampung City. Keywords: DHF, Spatial Analysis

scholarly journals Hyperventilation in Children with Dengue Hemorrhagic Fever (DHF)

2019 ◽  
Vol 31 (9-10) ◽  
pp. 245-56
Author(s):  
Kasim Y. A. ◽  
Anky Tri Rini K. E. ◽  
Sumarmo S. P. S.
Keyword(s):  
Dengue Hemorrhagic Fever ◽  
Dengue Shock Syndrome ◽  
Hemorrhagic Fever ◽  
Lung Edema ◽  
Respiratory Problems ◽  
Ventilatory Pattern ◽  
Grade Ii ◽  
Plasma Leakage ◽  
The Difference ◽  
Respiratory Disturbance

Many studies of Dengue Hemorrhagic Fever (DHF) have been done but only a few revealed the respiratory status. Respiratory problems arise. because of plasma leakage through the 'damaged capillaries, causing lung edema and in turn result in hypoxemia. This later on will be compensated by a hyperventilation state. During a 6-month-period (May to September 1988), two aspects were studied in 85 patients hospitalized with DHF. First, the ventilatory pattern and second, the result of giving oxygen support in improving the respiratory disturbance, in this case alveolar hyperventilation. The incidence of alveolar hyperventilation in DHF grade II (DHF II) and Dengue Shock Syndrome (DSS) differed significantly. Hypoxemia occurred in DHF II and DSS with no significant differences. The difference of the incidence of metabolic acidosis in DHF II and DSS were significant. In DHF II patients having had hyperventilation state, oxygen therapy decreased respiration rate significantly and increased the PaC02 though not significantly.

scholarly journals Immunopathogenesis of Dengue Hemorrhagic Fever

Virology ◽  
1999 ◽  
Vol 257 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Alan L. Rothman ◽  
Francis A. Ennis
Keyword(s):  
Dengue Hemorrhagic Fever ◽  
Hemorrhagic Fever
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