Triple positivity for nonstructural antigen 1, immunoglobulin M and immunoglobulin G is predictive of severe thrombocytopaenia related to dengue infection

2020 ◽  
Vol 129 ◽  
pp. 104509
Author(s):  
Sanjay de Mel ◽  
Basuru Uvindu Thilakawardana ◽  
Primesh de Mel ◽  
Choong Shi Hui Clarice ◽  
Malka Shalindi ◽  
...  
1979 ◽  
Vol 9 (4) ◽  
pp. 498-502
Author(s):  
D Dittmar ◽  
T J Cleary ◽  
A Castro

An enzyme-linked immunosorbent assay for the detection of antibodies to dengue virus is described. This method correlates well with a hemagglutination inhibition technique. The enzyme-linked immunosorbent assay can also be specific for human immunoglobulin M antibodies when a mu-chain-specific antiglobulin-enzyme conjugate and fractionated serum are employed. By using this technique, dengue immunoglobulin M antibodies were demonstrated in an infant suspected of having a recent dengue infection.


2020 ◽  
Vol 2 (1) ◽  
pp. 1-12
Author(s):  
Putri Ulandari ◽  
Vina Z. Latuconsina ◽  
Halidah Rahawarin

The dengue virus that has been injected through the bite of the Aedes mosquito will spread through the blood and cause primary viremia. This situation will stimulate the body's immune system to eliminate dengue infection, including the secretion of immunoglobulin M (IgM) and immunoglobulin G (IgG). Different immune system mechanisms will have an impact on the severity of dengue infection. This study aims to determine the relationship between IgM and IgG with the severity of dengue infection patients in RSUD. Dr. M. Haulussy and RS. Sumber Hidup Ambon in 2018. This research is an analytic cross-sectional approach that uses secondary data. The number of samples was 26 patients with purposive sampling. The result showed primary infections were at mild severity, while the secondary infection was found all severity. The analytic concluded there is no relation between IgM and IgG with the severity of dengue infection (p=0,237).


2020 ◽  
Vol 101 ◽  
pp. 497
Author(s):  
V. Abeysuriya ◽  
C. Choong Shi Hui ◽  
B.U. Thilakawardana ◽  
P. de Mel ◽  
C. de Mel ◽  
...  

2020 ◽  
Vol 57 (12) ◽  
pp. 1131-1134
Author(s):  
Mohan D. Gupte ◽  
Manish Gupte ◽  
Suchit Kamble ◽  
Arati Mane ◽  
Suvarna Sane ◽  
...  

2021 ◽  
Vol 9 (2) ◽  
pp. 51-57
Author(s):  
Safia S. I. Blbas ◽  
Hiwa A. Ahmad ◽  
Dawan J. Hawezy ◽  
Hemn Shawgery ◽  
Hersh N. Bahadin

Coronavirus is a pandemic disease. In most cases, the exact infection rate cannot be determined as not everybody can be tested for the virus, even though some of them carry the virus silently. Therefore, detection of antibodies of this virus is more practical to give us a better clue about the rate of infection because the asymptomatic people can be tested too. The serological detection of anti-Severe Acute Respiratory Syndrome-Coronavirus (SARS-COV-2) antibodies among asymptomatic and moderate symptomatic individuals gives us the vital point to understanding the prevalence rate of COVID-19 among the population. Total of (436) volunteers were participated, (96) from teaching staff, (172) employee, and (168) students. Anti-SARS-COV-2 immunoglobulin G (IgG) and Immunoglobulin M (IgM) were detected in the serum by ELISA technique, and complete blood count was performed for all participants. The number of seropositive of anti-SARS-COV-2/IgG was (159), whereas IgM was (66). The highest prevalence rate of IgG detected among participants with family member infected with coronavirus (42.7%). Total WBCs count significantly increased among IgM positive participants. Many asymptomatic people were infected with coronavirus, which lead to more spreading of the virus among the population. Therefore, mass screening of the population for specific antibody against coronavirus is important to reduce the infection rate.


1979 ◽  
Vol 9 (1) ◽  
pp. 120-127
Author(s):  
D W Bradley ◽  
H A Fields ◽  
K A McCaustland ◽  
J E Maynard ◽  
R H Decker ◽  
...  

A competitive binding radioimmunoassay (CBA) for antibody to hepatitis A virus (HAV) was evaluated and compared with a standard solid-phase radioimmunoassay for anti-HAV, CBA was found to be sensitive and specific for the detection of anti-HAV, as demonstrated by the 98% concordance of CBA and solid-phase radioimmunoassay test results. The standard CBA test was modified for the differential detection of acute (immunoglobulin M) and convalescent (immunoglobulin G) anti-HAV by incorporation of a step in which immunoglobulin G anti-HAV was preferentially absorbed with S. aureus cells (protein A). The modified CBA test was shown to be capable of differentiating between acute- and convalescent-phase sera. The modified CBAM test was able to detect immunoglobulin M anti-HAV up to approximately 4 weeks after the onset of illness.


2019 ◽  
Vol 220 (9) ◽  
pp. 1435-1443 ◽  
Author(s):  
Bridget E Barber ◽  
Matthew J Grigg ◽  
Kim Piera ◽  
Fiona H Amante ◽  
Timothy William ◽  
...  

Anti-phosphatidylserine antibodies (PS-Abs) are elevated in Malaysian patients with vivax and falciparum malaria and are highest in vivax malaria. In vivax and falciparum malaria, PS-Abs correlate inversely with admission and nadir hemoglobin, suggesting that PS-Abs contribute to anemia from these species.


1978 ◽  
Vol 87 (3) ◽  
pp. 412-415 ◽  
Author(s):  
Arnold E. Katz ◽  
John O. Nysather ◽  
Lee A. Harker

— Serum immunoglobulin A (IgA), immunoglobulin G (IgG), and immunoglobulin M (IgM) levels were determined on 245 patients with carcinoma of the head and neck and on 92 controls. Ratios of these levels were calculated for each subject. The patients with cancer demonstrated elevated serum IgA levels ( P <.0001) and elevated IgA/IgM and IgA/IgG ratios ( P <.05). No differences were noted when the IgM/IgG ratios were compared between the cancer and the control groups. These observations are offered as evidence that previously reported elevations of serum IgA levels in patients with carcinoma of the head and neck are not merely an index of nonspecific increased immunoglobulin production in these patients.


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