Selection of component drug in activating blood flow and removing blood stasis of Chinese herbal medicinal formula for dairy cow mastitis by hemorheological method

2008 ◽  
Vol 116 (2) ◽  
pp. 313-317 ◽  
Author(s):  
Yu Lu ◽  
Yuan-Liang Hu ◽  
Xiang-Feng Kong ◽  
De-Yun Wang
2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Yi Jing Yang ◽  
Jun Peng ◽  
Deng Ying ◽  
Qing Hua Peng

Retinitis pigmentosa (RP) represents a clinically and genetically heterogeneous disease characterized by progressive photoreceptor loss. In recent years, research has been rarely made in blood flow affected in RP. The specific mechanism of blood flow affected in RP is not completely clear. A number of studies indicated that the decreased blood flow was related to RP. According to clinical observation and treatment experience, Chinese medicine considered that blood stasis runs throughout the RP disease progression, and the blood stasis corresponding to Chinese herbal medicine has a positive effect on the clinical treatment of RP. Therefore, we proposed that the decreased blood flow may participate in the lesion. In this article, we will review the findings on the decreased blood flow affected in RP from the perspective of modern medicine and Chinese medicine.


2001 ◽  
Vol 120 (5) ◽  
pp. A248-A248
Author(s):  
N KAWASAKI ◽  
K NARIAI ◽  
M NAKAO ◽  
K NAKADA ◽  
N HANYUU ◽  
...  

2017 ◽  
Vol 63 (5) ◽  
pp. 766-769
Author(s):  
Nikolay Agarkov ◽  
Pavel Tkachenko ◽  
Dmitriy Kicha ◽  
Vitaliy Aksenov ◽  
Aleksandr Ivanov ◽  
...  

Analysis of ultrasonic blood flow changes in uterine and ovarian arteries and veins in 92 patients with ovarian cancer and 87 patients with chronic salpingoophoritis has allowed to identify the leading differential diagnostic criteria, which include minimum diastolic blood flow velocity, resistance index, while fast hyperemia, the index of venous outflow diastolic index and index of peripheral resistance. Based on a selection of leading differential diagnostic criteria for ovarian cancer and chronic salpingoophoritis developed a network model of differentiation of these groups of patients, streamlining the differential diagnostic process


Author(s):  
Hetao Huang ◽  
Jianke Pan ◽  
Yanhong Han ◽  
Lingfeng Zeng ◽  
Guihong Liang ◽  
...  

Aim and Objective: To evaluate the efficacy and safety of Chinese herbal medicines for promoting blood circulation and removing blood stasis (PBCRBSM) in preventing deep venous thrombosis (DVT) after total hip arthroplasty (THA). Materials and Methods: The Databases were searched for studies comparing the preventive abilities of PBCRBSM and Western medicine, such as low molecular weight heparin (LMWH), rivaroxaban, and aspirin, as well as for randomized controlled trials on DVT after THA. Data were analyzed using RevMan 5.3 software. Results: A total of 3254 randomized controlled trials were included, including 1630 cases in the experimental group and 1624 cases in the control group. Meta-analysis showed that compared with Western medicine, PBCRBSM reduced the incidence of DVT (OR=0.38, 95% CI [0.30, 0.48], P < 0.001); prolonged activated partial thromboplastin time (APTT) (SMD=0.44, 95% CI [0.35, 0.53], P < 0.001); reduced D-dimer (SMD=-0.75, 95% CI [-0.84,-0.65], P < 0.001), FIB (SMD=-0.61, 95% CI [-0.72, -0.50], P < 0.001), blood viscosity (P<0.01), circumference difference in lower extremities (P<0.01), venous blood flow velocity (SMD=0.97, 95% CI [0.77, 1.16], P < 0.001), and drainage volume (SMD=-1.53, 95% CI [-1.71, -1.35], P < 0.001); and reduced adverse reactions (OR = 0.32, 95% CI [0.19, 0.56], P < 0.001). There was no significant difference in prolonging prothrombin time (PT) between traditional Chinese medicine and Western medicine (SMD = 0.07, 95% CI [-0.0.01). 3, 0.16], P > 0.05. Conclusion: PBCRBSM is an effective method for preventing DVT after THA and has fewer adverse effects.


2021 ◽  
pp. 039139882110130
Author(s):  
Guang-Mao Liu ◽  
Fu-Qing Jiang ◽  
Xiao-Han Yang ◽  
Run-Jie Wei ◽  
Sheng-Shou Hu

Blood flow inside the left ventricle (LV) is a concern for blood pump use and contributes to ventricle suction and thromboembolic events. However, few studies have examined blood flow inside the LV after a blood pump was implanted. In this study, in vitro experiments were conducted to emulate the intraventricular blood flow, such as blood flow velocity, the distribution of streamlines, vorticity and the standard deviation of velocity inside the LV during axial blood pump support. A silicone LV reconstructed from computerized tomography (CT) data of a heart failure patient was incorporated into a mock circulatory loop (MCL) to simulate human systemic circulation. Then, the blood flow inside the ventricle was examined by particle image velocimetry (PIV) equipment. The results showed that the operating conditions of the axial blood pump influenced flow patterns within the LV and areas of potential blood stasis, and the intraventricular swirling flow was altered with blood pump support. The presence of vorticity in the LV from the thoracic aorta to the heart apex can provide thorough washing of the LV cavity. The gradually extending stasis region in the central LV with increasing blood pump support is necessary to reduce the thrombosis potential in the LV.


2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Tai-Yuan Chuang ◽  
Chia-Ying Lien ◽  
Chih-Hsiang Hsu ◽  
Chen-Wen Lu ◽  
Chung-Hsin Wu

Hypothyroidism frequently causes cardiopulmonary dysfunction, such as heart failure and respiratory and metabolic deficiencies. This study investigated the effects of Chinese herbal formula B307 on thyroidectomy-induced cardiopulmonary exercise dysfunction in rats. Twenty male rats were equally divided into four groups: negative control with sham treatment, positive control with oral B307 treatment only, thyroidectomy treatment only, and thyroidectomy with B307 posttreatment groups. The feeding dose of B307 was 50 mg/kg per day for 14 days. We examined and then compared the thyroid-stimulating hormone (TSH), free triiodothyronine (T3), free thyroxine (T4), and reactive oxygen species (ROS) from the blood of these four groups. Also, we compared the body weight, neck subcutaneous blood flow, cardiac ejection function, cardiopulmonary exercise function of oxygen consumption (VO2), carbon dioxide production (VCO2), and respiratory quotient (RQ = VCO2/VO2) among the four groups. Our results indicated that thyroidectomized rats had significantly decreased body weight, neck subcutaneous blood flow, cardiac ejection function, serum T3 and T4, and VO2 and VCO2, but had significantly increased ROS and TSH levels and RQ values compared with sham rats (P<0.01–0.05). In addition, thyroidectomized rats receiving oral B307 treatment had significantly increased body weight, neck subcutaneous blood flow, cardiac ejection function, and VO2, but significantly decreased ROS and TSH levels and VCO2 and RQ values compared with thyroidectomized rats (P<0.01–0.05). We suggest that the B307 could be a protective and beneficial alternative treatment for thyroidectomy-induced cardiopulmonary exercise dysfunction.


1990 ◽  
Vol 110 (7) ◽  
pp. 504-508 ◽  
Author(s):  
Tamotsu NIKAIDO ◽  
Taichi OHMOTO ◽  
Takashi KUGE ◽  
Akiko YANAGISAWA ◽  
Kiyomi TEINOZAWA ◽  
...  

2016 ◽  
Vol 36 (suppl_1) ◽  
Author(s):  
Kaoru Tateno ◽  
Yoshihide Fujimoto ◽  
Hiroshi Hasegawa ◽  
Toshio Nagai ◽  
Yoshio Kobayashi

Background: Clinical trials of therapeutic angiogenesis that treat chronic critical limb ischemia (CLI) are revealing mixed results. This may partly be due to unapt patient selection or suboptimal study protocols. Here, from our registry, we report demographic and procedural characteristics of patients who underwent major limb amputation despite therapeutic angiogenesis. Methods: Registry of CLI patients who were treated by peripheral blood mononuclear cell (PBMNC) implantation was retrospectively analyzed. Cases that underwent major limb amputation within 6 months of the therapy were further investigated to clarify any features that might have affected their limb outcomes. Results and Discussions: Among total of 112 patients in the registry, eight cases lost to follow up and were excluded from this study. Sixteen patients (16/104, 15.4%) underwent major limb amputation within 6 months after therapeutic angiogenesis. Six amputees had active infection in the treated limb. Unlike excellent outcome by bone marrow derived cells, any patients with systemic sclerosis treated by PBMNC had poor limb salvage. However, half (8/16) of the amputees had experienced blood flow recovery, at least for transient period of two weeks. Among these patients, five limbs showed significant recovery of crural blood flow, while in the ipsilateral foot, distal blood flow deteriorated, indicating the flow steal phenomenon induced by cell therapy, which induces strong vasodilatation. Excluding patients with active infection or systemic sclerosis halved the limb amputation rate. Careful selection of sites to implant cells according to anatomical distribution of arterial blood flow could even have improved the limb salvage rate. Conclusion: When designing a clinical trial of therapeutic angiogenesis, (1) excluding patients with active infections, (2) proper treatment site considering anatomical distribution of arterial blood flow to avoid steal phenomenon, and (3) selection of cell source according to etiology of CLI, may clarify the efficacy of therapeutic angiogenesis.


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